{"id":17476,"date":"2020-12-10T12:20:35","date_gmt":"2020-12-10T17:20:35","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=17476"},"modified":"2025-08-25T12:27:44","modified_gmt":"2025-08-25T16:27:44","slug":"common-drug-classes-2020","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/common-drug-classes-2020\/","title":{"rendered":"These were the most-filled drug classes on SingleCare in 2020"},"content":{"rendered":"

When it comes to saving money at the pharmacy, SingleCare users know they can present their card for discounts on more than 10,000 prescriptions. And over the past year, cardholders have taken full advantage of these savings, filling prescriptions that ran the gamut from thyroid medications to topical acne treatments.\u00a0<\/span><\/p>\n

When it came to the most common drug classes of 2020, a number of trends emerged. Antihypertensives were popular\u2014unsurprising given the prevalence of heart attack and stroke among Americans\u2014as were thyroid agents and antidiabetics. Vitamins, pain relievers, and antihistamines were also necessities for 2020. And with depression on the rise due to the COVID-19 global pandemic, antidepressants ranked high, too.\u00a0<\/span><\/p>\n

The most-filled drug classes of 2020*<\/span><\/h2>\n

There are many more findings to be had in the full list. So without further ado, here are the 10 most common drug classes (and the top five medications in each category) on SingleCare in 2020:<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Drug class<\/b><\/td>\nPopular Rx<\/b><\/td>\n<\/tr>\n
1. Antihypertensives<\/span><\/td>\nGet lisinopril coupon<\/span><\/a><\/td>\n<\/tr>\n
Get losartan coupon<\/span><\/a><\/td>\n<\/tr>\n
Get lisinopril\/hydrochlorothiazide coupon<\/span><\/a><\/td>\n<\/tr>\n
Get enalapril coupon<\/span><\/a><\/td>\n<\/tr>\n
Get <\/span>losartan\/hydrochlorothiazide coupon\u00a0<\/span><\/a><\/td>\n<\/tr>\n
2. Antidepressants<\/span><\/td>\nGet trazodone coupon<\/span><\/a><\/td>\n<\/tr>\n
Get escitalopram coupon<\/span><\/a><\/td>\n<\/tr>\n
Get sertraline coupon<\/span><\/a><\/td>\n<\/tr>\n
Get fluoxetine coupon<\/span><\/a><\/td>\n<\/tr>\n
Get citalopram coupon<\/span><\/a><\/td>\n<\/tr>\n
3. Thyroid agents<\/span><\/td>\nGet levothyroxine <\/span>coupon<\/span><\/a><\/td>\n<\/tr>\n
Get armour thyroid coupon<\/span><\/a><\/td>\n<\/tr>\n
Get Synthroid coupon<\/span><\/a><\/td>\n<\/tr>\n
Get Euthyrox coupon<\/span><\/a><\/td>\n<\/tr>\n
Get methimazole coupon<\/span><\/a><\/td>\n<\/tr>\n
4. Analgesics\/anti-inflammatories<\/span><\/td>\nGet ibuprofen coupon<\/span><\/a><\/td>\n<\/tr>\n
Get meloxicam coupon<\/span><\/a><\/td>\n<\/tr>\n
Get naproxen coupon<\/span><\/a><\/td>\n<\/tr>\n
Get ketorolac coupon<\/span><\/a><\/td>\n<\/tr>\n
Get diclofenac sodium coupon<\/span><\/a><\/td>\n<\/tr>\n
5. Antidiabetics<\/span><\/td>\nGet metformin coupon<\/span><\/a><\/td>\n<\/tr>\n
Get glipizide coupon<\/span><\/a><\/td>\n<\/tr>\n
Get metformin ER coupon<\/span><\/a><\/td>\n<\/tr>\n
Get glimepiride coupon<\/span><\/a><\/td>\n<\/tr>\n
Get Lantus Solostar coupon<\/span><\/a><\/td>\n<\/tr>\n
6. Vitamins<\/span><\/td>\nGet vitamin D coupon<\/span><\/a><\/td>\n<\/tr>\n
Get vitamin D3 coupon<\/span><\/a><\/td>\n<\/tr>\n
Get vitamin C coupon<\/span><\/a><\/td>\n<\/tr>\n
Get vitamin B-6 coupon<\/span><\/a><\/td>\n<\/tr>\n
Get vitamin B-1 coupon<\/span><\/a><\/td>\n<\/tr>\n
7. Penicillins<\/span><\/td>\nGet amoxicillin coupon<\/span><\/a><\/td>\n<\/tr>\n
Get amoxicillin\/clavulanate coupon<\/span><\/a><\/td>\n<\/tr>\n
Get penicillin v potassium coupon<\/span><\/a><\/td>\n<\/tr>\n
Get dicloxacillin coupon<\/span><\/a><\/td>\n<\/tr>\n
Get ampicillin coupon<\/span><\/a><\/td>\n<\/tr>\n
8. Dermatologicals<\/span><\/td>\nGet triamcinolone acetate coupon<\/span><\/a><\/td>\n<\/tr>\n
Get diclofenac sodium coupon<\/span><\/a><\/td>\n<\/tr>\n
Get mupirocin coupon<\/span><\/a><\/td>\n<\/tr>\n
Get tretinoin coupon<\/span><\/a><\/td>\n<\/tr>\n
Get hydrocortisone coupon<\/span><\/a><\/td>\n<\/tr>\n
9. Beta blockers<\/span><\/td>\nGet metoprolol succinate ER coupon<\/span><\/a><\/td>\n<\/tr>\n
Get metoprolol tartrate coupon<\/span><\/a><\/td>\n<\/tr>\n
Get carvedilol coupon<\/span><\/a><\/td>\n<\/tr>\n
Get atenolol coupon<\/span><\/a><\/td>\n<\/tr>\n
Get Bystolic coupon<\/span><\/a><\/td>\n<\/tr>\n
10. Antihistamines<\/span><\/td>\nGet cetirizine coupon<\/span><\/a><\/td>\n<\/tr>\n
Get loratadine coupon<\/span><\/a><\/td>\n<\/tr>\n
Get fexofenadine coupon<\/span><\/a><\/td>\n<\/tr>\n
Get promethazine coupon<\/span><\/a><\/td>\n<\/tr>\n
Get banophen coupon<\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

1. Antihypertensives<\/span><\/h3>\n

High blood pressure medications were the most common drug class among SingleCare card users in 2020, which isn\u2019t surprising to Bethesda, Maryland\u2013based primary care physician and internist<\/span> Matthew Mintz, MD, FACP<\/span><\/a>. \u201c<\/span>The single leading cause of death in the U.S. (even with COVID-19) is heart attacks,\u201d Dr. Mintz says. \u201cOne of the major contributors to heart attacks is high blood pressure or hypertension.\u201d High blood pressure also increases the risk of stroke (the second leading cause of death in the U.S.), which is why it\u2019s so important to maintain healthy levels, defined as a <\/span>blood pressure below 120\/80 mmHg., <\/span>according to the<\/span> American College of Cardiology<\/span><\/a>.\u00a0<\/span><\/p>\n

Unfortunately, many Americans are falling short: 45% have hypertension, according to the<\/span> Centers for Disease Control and Prevention<\/span><\/a> (CDC), and only about 1 in 4 have their condition under control. While lifestyle changes like exercising more and eating a healthy diet can go a long way toward lowering blood pressure, they sometimes aren\u2019t enough on their own, and that\u2019s when a medication may be necessary\u2014especially for older Americans.\u00a0<\/span><\/p>\n

\u201c<\/span>High blood pressure is very much affected by age,\u201d Dr. Mintz says. \u201cAs we get older, our blood vessels age and stiffen, causing a rise in blood pressure. At one time, hypertension was thought to be a natural aging process, but we now know that treating high blood pressure can reduce heart attacks and strokes in seniors.\u201d<\/span><\/p>\n

RELATED: <\/b>How to lower blood pressure quickly and naturally<\/b><\/a><\/p>\n

2. Antidepressants<\/span><\/h3>\n

Despite their name, medicines that fall in the antidepressant category treat a host of mental illnesses, including generalized anxiety disorder (GAD), obsessive compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and social anxiety disorder.\u00a0<\/span><\/p>\n

Approximately 40 million adults in the U.S. have some sort of anxiety disorder, according to the<\/span> Anxiety and Depression Association of America<\/span><\/a>, yet only <\/span>37% of those people are being treated. Another potential factor driving antidepressant use in 2020 may very well be the pandemic. For many, mental health issues have been a particular challenge during quarantine, with<\/span> one study<\/span><\/a> suggesting depression rates have tripled among U.S. adults this past year.<\/span><\/p>\n

RELATED: <\/b>Medications that treat anxiety and depression<\/b><\/a><\/p>\n

3. Thyroid agents<\/span><\/h3>\n

Another common ailment among Americans is thyroid disease\u2014more than 12% of the population will develop some sort of thyroid condition during their lifetime, according to the<\/span> American Thyroid Association<\/span><\/a>. Women, in particular, are susceptible; they are five to eight times more likely than men to develop an issue.\u00a0<\/span><\/p>\n

Thyroid conditions vary\u2014from hyperthyroidism, in which the thyroid produces too many hormones\u2014to hypothyroidism, in which the thyroid produces too few hormones. \u201c<\/span>There are many causes for hypothyroidism but the most common cause is an autoimmune disease known as Hashimoto’s thyroiditis,\u201d says Dr. Mintz. \u201cPatients whose thyroids don’t make enough thyroid hormone usually need a thyroid replacement, like levothyroxine. Without it, patients can develop symptoms of low thyroid which include weight gain, dry skin, constipation, and hair loss.\u201d<\/span><\/p>\n

RELATED: <\/b>Hypothyroidism treatments and medications<\/b><\/a><\/p>\n

4. Analgesics\/anti-inflammatories<\/span><\/h3>\n

Commonly referred to as pain relievers, analgesics come in multiple forms, from over-the-counter pills (Tylenol) to prescription medications (meloxicam). The most popular analgesic among SingleCare card users in 2020 was, perhaps unsurprisingly, ibuprofen.\u00a0<\/span><\/p>\n

Typically branded as Advil or Motrin, ibuprofen is a <\/span>nonsteroidal anti-inflammatory drug (NSAID) used to treat fever and pain and is available without a prescription. (Doctors may also prescribe ibuprofen at a higher dose.) Among the over-the-counter NSAIDs, ibuprofen is considered to be the most gentle on the GI tract.<\/span><\/p>\n

RELATED: <\/b>Is Tylenol an NSAID?<\/b><\/a><\/p>\n

5. Antidiabetics<\/span><\/h3>\n

Hovering near the middle of SingleCare\u2019s 2020 list are antidiabetics, the most popular of which was metformin (typically branded as Glucophage, Riomet, or Glumetza).\u00a0<\/span><\/p>\n

\u201c<\/span>Metformin works in multiple ways to help control blood sugar levels,\u201d <\/span>says Kristi C. Torres, Pharm.D. in Austin, Texas, a member of SingleCare\u2019s Medical Review Board.<\/span> \u201cIt slows the production of glucose. It also decreases the intestinal absorption of glucose. Finally, it improves insulin sensitivity by increasing peripheral glucose utilization. The end result of these actions are lower blood sugar levels and better glycemic control for diabetic patients.\u201d<\/span><\/p>\n

The CDC estimates<\/span><\/a> that 34.2 million Americans (of all ages) have diabetes, with diabetes rates increasing with age.\u00a0 <\/span>\u00a0\u00a0<\/span><\/p>\n

RELATED: <\/b>Diabetes statistics<\/b><\/a><\/p>\n

6. Vitamins<\/span><\/h3>\n

Vitamins were another popular purchase among SingleCare users in 2020, with vitamin D (in various forms) far and away outpacing its competitors. Vitamin D plays a number of roles in the body, including aiding in calcium absorption, immune functions, and muscle and nerve activities, according to the\u00a0<\/span>National Institutes of Health<\/span><\/a>. Too little vitamin D can lead to brittle bones, a condition known as rickets in children and osteomalacia in adults. In addition to supplements, vitamin D can be acquired through exposure to sunshine and fatty fish like salmon and tuna. After vitamin D, vitamin C was the most popular purchase, followed by vitamin B-6 and vitamin B-1.\u00a0\u00a0<\/span><\/p>\n

RELATED: <\/b>What vitamins should I take?<\/b><\/a><\/p>\n

7. Penicillins<\/span><\/h3>\n

Scottish researcher Sir Alexander Fleming discovered penicillin in 1928, and over the ensuing century, the drug has become the most-prescribed antibiotic around the world. \u201c<\/span>Even though penicillin-derived antibiotics have been around a very long time, they still work in a variety of infections and thus remain quite popular,\u201d explains Dr. Mintz. \u201cOther than causing an allergic reaction, which sometimes can be serious, penicillin antibiotics are usually well tolerated by most people.\u201d<\/span><\/p>\n

Penicillin, and its relative amoxicillin<\/span><\/a>, are used to treat a number of bacterial infections, including ear, lower respiratory, urinary tract, and skin infections. As far as efficacy goes, amoxicillin is able to treat a broader range of bacteria than penicillin. However, neither drug\u2014nor any that fall in the penicillin family\u2014can or should be used to treat viral infections.<\/span><\/p>\n

RELATED: <\/b>Do you really have a penicillin allergy? Check again.<\/b><\/a><\/p>\n

8. Dermatologicals<\/span><\/h3>\n

As the name would suggest, dermatologicals are used to treat skin conditions, and among SingleCare user<\/span>s, triamcinolone cream was the most popular. \u201c<\/span>Topical triamcinolone is used to treat a variety of skin conditions including exfoliative dermatitis, hypersensitivity reactions, and reactions related to lupus and Stevens-Johnson syndrome,\u201d Dr. Torres says. \u201c[The dental paste] can also be used topically in the mouth for oral inflammation.\u201d\u00a0<\/span><\/p>\n

Runners-up in the dermatologicals category include tretinoin, a vitamin A derivative otherwise known as Retin-A, which treats acne and sun-damaged skin; finasteride, otherwise known as Propecia, which is an oral tablet used to treat hair loss in men; and hydrocortisone, which is used to treat itchy, swollen skin and can ease eczema symptoms.<\/span><\/p>\n

RELATED: <\/b>Psoriasis vs. eczema: Can you treat them the same way?<\/b><\/a><\/p>\n

9. Beta blockers<\/span><\/h3>\n

Beta blockers are the second blood pressure medication class to rank among SingleCare users this year. They work by blocking \u201cbeta adrenergic receptors in the heart and vasculature, which causes a decrease in heart rate and cardiac output,\u201d Dr. Torres says. \u201cThey can be prescribed for a variety of reasons including hypertension, angina (chest pain), and heart failure.\u201d\u00a0<\/span><\/p>\n

Beta blockers are often also prescribed to patients who have had a heart attack, adds Dr. Torres, as they have been shown to decrease mortality levels.<\/span><\/p>\n

RELATED: <\/b>What is a beta blocker?<\/b><\/a>\u00a0<\/span><\/p>\n

10. Antihistamines<\/span><\/h3>\n

Rounding out the top 10 list are antihistamines, which block histamine receptors and are used for a number of allergy-related conditions. \u201cThese can include allergic rhinitis (runny nose), itching, and hypersensitivity reactions,\u201d Dr. Torres says. Antihistamines can also be used for bug bite reactions and, in some cases, as a short-term insomnia antidote. \u201cBenadryl (diphenhydramine) is known to cause significant drowsiness as a side effect, and is sometimes used with the intent to help with sleep,\u201d Dr. Torres says. Check with your doctor before using Benadryl, though, because certain conditions are not compatible with the medication.\u00a0<\/span><\/p>\n

RELATED: <\/b>Non-drowsy Benadryl: What are your options?<\/b><\/a><\/p>\n

*The most-filled drug classes were ranked by net prescription fills through SingleCare from Jan. 1, 2020 through Oct. 31, 2020, excluding opioids and weight-loss drugs. <\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"

When it comes to saving money at the pharmacy, SingleCare users know they can present their card for discounts on more than 10,000 prescriptions. And over the past year, cardholders have taken full advantage of these savings, filling prescriptions that ran the gamut from thyroid medications to topical acne treatments.\u00a0 When it came to the […]<\/p>\n","protected":false},"author":85,"featured_media":17344,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[20601],"coauthors":[8215],"class_list":["post-17476","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-company","tag-singlecare-year-in-review","wpautop"],"acf":[],"yoast_head":"\n10 most common drug classes filled on SingleCare in 2020<\/title>\n<meta name=\"description\" content=\"What types of medications did Americans take in 2020? Antihypertensives, antidepressants, and thyroid agents were some of the most common drug classes.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/common-drug-classes-2020\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"These are most-filled drug classes on SingleCare in 2020\" \/>\n<meta property=\"og:description\" content=\"What medications did Americans take this year? Learn the most common.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/common-drug-classes-2020\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2020-12-10T17:20:35+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-08-25T16:27:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/12\/Blog_121020_Most_filled_drugs_2020.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Amy Wilkinson\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"These are most-filled drug classes on SingleCare in 2020\" \/>\n<meta name=\"twitter:description\" content=\"What medications did Americans take this year? Learn the most common.\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Amy Wilkinson\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/\"},\"author\":{\"name\":\"Janice Rodden\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/169a1d8c8b88282cc3b792a394fc3575\"},\"headline\":\"These were the most-filled drug classes on SingleCare in 2020\",\"datePublished\":\"2020-12-10T17:20:35+00:00\",\"dateModified\":\"2025-08-25T16:27:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/\"},\"wordCount\":1638,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/12\\\/Blog_121020_Most_filled_drugs_2020.png\",\"keywords\":[\"SingleCare: Year in Review\"],\"articleSection\":[\"Company\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/\",\"name\":\"10 most common drug classes filled on SingleCare in 2020\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/common-drug-classes-2020\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/12\\\/Blog_121020_Most_filled_drugs_2020.png\",\"datePublished\":\"2020-12-10T17:20:35+00:00\",\"dateModified\":\"2025-08-25T16:27:44+00:00\",\"description\":\"What types of medications did Americans take in 2020? 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