{"id":19290,"date":"2021-02-19T09:30:16","date_gmt":"2021-02-19T14:30:16","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=19290"},"modified":"2021-03-31T12:58:08","modified_gmt":"2021-03-31T16:58:08","slug":"prozac-and-pregnancy","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/prozac-and-pregnancy\/","title":{"rendered":"Is it safe to take Prozac (fluoxetine) during pregnancy?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Pregnancy expands your health considerations to include your growing baby. That\u2019s why finding a pregnancy-safe medication to treat depression and anxiety is a top priority for many expectant parents\u2014 especially since several<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/safe-medication-during-pregnancy\/\"><span style=\"font-weight: 400;\">drugs<\/span><\/a><span style=\"font-weight: 400;\">, including antidepressants, pose some risk to mother and baby during pregnancy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But when you consider that <\/span><a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2724195\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">1 in 7 women<\/span><\/a><span style=\"font-weight: 400;\"> experience a depressive episode during pregnancy or following childbirth, having access to treatment, including antidepressant medications like Prozac (fluoxetine), is critical.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to the<\/span> <a href=\"https:\/\/www.acog.org\/en\/Womens%20Health\/FAQs\/Depression\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">American College of Obstetricians and Gynecologists<\/span><\/a><span style=\"font-weight: 400;\"> (ACOG), depression during pregnancy can have adverse health effects on both the mom-to-be and baby. This includes problems with the growth of the fetus, premature birth, low birth weight, and complications after birth.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Deciding whether to start or continue taking an antidepressant to treat<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/perinatal-depression-antidepressants\/\"><span style=\"font-weight: 400;\">perinatal depression<\/span><\/a><span style=\"font-weight: 400;\"> is something you need to discuss with your healthcare provider. They can help you determine if you should continue taking Prozac while pregnant. Here are the basics you need to know.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What is Prozac?<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/prozac\/what-is\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> is a brand name for the drug fluoxetine, which belongs to a class of antidepressants called selective serotonin reuptake inhibitors or SSRIs.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">SSRIs work by increasing the amount of serotonin, a normal chemical found in the brain. Providers often prescribe it for depression, panic disorder, obsessive-compulsive disorder, anxiety disorders, and post-traumatic stress disorder.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Prozac and pregnancy: Is it safe?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many expectant parents taking Prozac worry about the risk of birth defects. But the good news is despite a slight increased risk of certain birth defects from some SSRIs, including fluoxetine, the actual risk among babies born to women taking one of these antidepressants is still very low, according to a U.S. Centers for Disease Control and Prevention (CDC) <\/span><a href=\"https:\/\/www.bmj.com\/content\/351\/bmj.h3190\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A<\/span> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5595931\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">systematic review and meta-analysis<\/span><\/a><span style=\"font-weight: 400;\"> found that fluoxetine during pregnancy is associated with a slightly increased risk of cardiovascular malformations in infants. Although the risk is small, <\/span><a href=\"https:\/\/www.communitypsychiatry.com\/providers\/dr-priyanka-m-d\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Priyanka Priyanka<\/span><\/a><span style=\"font-weight: 400;\">, MD, psychiatrist and medical director at Community Psychiatry, says it\u2019s important to talk with your doctor about the pros and cons of taking Prozac during pregnancy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cUntreated depression poses a significant risk during pregnancy, so it&#8217;s always worth reviewing risks and benefits of using medications,\u201d Dr. Priyanka says. Overall, research suggests that the benefits of using an antidepressant like Prozac outweighs the risk associated with untreated depression or anxiety during pregnancy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019re taking Prozac, you might be wondering if the drug can make it harder to get pregnant or increase the risk of miscarriage once you are pregnant. More research is required, but <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4965341\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">one study<\/span><\/a><span style=\"font-weight: 400;\"> suggested a mild reduction in fertility when taking antidepressants.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There\u2019s also minimal information about the risk of miscarriage. That said, one<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25198261\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">study<\/span><\/a><span style=\"font-weight: 400;\"> found that the risk of miscarriage was similar between women exposed to SSRIs during early pregnancy and women who discontinued SSRI treatment before pregnancy.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Can you suddenly stop taking Prozac when you find out you\u2019re pregnant?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you\u2019re considering coming off of Prozac during pregnancy, it\u2019s critical that you<\/span> <a href=\"https:\/\/www.nimh.nih.gov\/health\/publications\/perinatal-depression\/index.shtml\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">do not stop taking it suddenly<\/span><\/a><span style=\"font-weight: 400;\">. It\u2019s also important to discuss this with your provider before making any decision regarding medications. They will be able to advise you on the safest options for your pregnancy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The sudden discontinuation of antidepressants during pregnancy is not recommended. \u201cThis could potentially lead to worsening mood and anxiety symptoms, which could adversely affect both mom and baby,\u201d explains <\/span><a href=\"https:\/\/www.communitypsychiatry.com\/providers\/leela-magavi-m-d\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Leela R. Magavi,<\/span><\/a> <span style=\"font-weight: 400;\">MD, psychiatrist and regional medical director at Community Psychiatry.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Magavi points to research that indicates that fluoxetine, or Prozac, is one of the safest antidepressants you can take during pregnancy and breastfeeding. If you would rather discontinue medications during pregnancy, Dr. Magavi recommends consulting with a physician who can evaluate your mood state as the dose is gradually decreased over time.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How much Prozac is safe to take during pregnancy?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In general, the recommended<\/span> <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/018936s108lbl.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">dose of Prozac<\/span><\/a><span style=\"font-weight: 400;\"> ranges from 10 mg per day for panic disorder to 60 mg per day for bulimia nervosa. The initial dose for depression is 20 mg per day, but your provider may adjust that dosage up or down depending on symptoms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Dr. Priyanka, the general recommendation is to stay on the dose that provides good control of symptoms of depression. If you take a higher than average dose, Dr. Priyanka says there may be a reason to adjust the dose during pregnancy, but this should be discussed in detail with your provider before making any decisions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIf it\u2019s decided that lowering the dose is a relatively safe option, it should be done under close monitoring and possibly may require augmentation with non-pharmacological treatment options like psychotherapy,\u201d she says.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Is Prozac safe to take while breastfeeding?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Medications that are relatively safe during pregnancy are often safe to take while breastfeeding. Antidepressants like Prozac are generally considered<\/span> <a href=\"https:\/\/www.singlecare.com\/blog\/antidepressants-breastfeeding-nursing-moms\/\"><span style=\"font-weight: 400;\">safe to take while breastfeeding<\/span><\/a><span style=\"font-weight: 400;\">; however, <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK501186\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">research<\/span><\/a><span style=\"font-weight: 400;\"> shows that <\/span><span style=\"font-weight: 400;\">the average amount of the drug in breastmilk is higher with fluoxetine than with most other SSRIs such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-and-breastfeeding\/\"><span style=\"font-weight: 400;\">sertraline (Zoloft)<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Adverse effects from taking fluoxetine while breastfeeding include an increase in colic, fussiness, and drowsiness. If you have concerns about using Prozac while breastfeeding, make sure to talk to your healthcare provider about the risks and benefits before making any decisions.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What antidepressants are safe to take during pregnancy and breastfeeding?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The SSRIs<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/celexa\"><span style=\"font-weight: 400;\">Celexa<\/span><\/a><span style=\"font-weight: 400;\"> (citalopram),<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><span style=\"font-weight: 400;\"> (sertraline), and<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/prozac\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> (fluoxetine) are often the go-to antidepressants to use during pregnancy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">That said, your doctor may also talk to you about serotonin-norepinephrine reuptake inhibitors (SNRIs) like<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/cymbalta\"><span style=\"font-weight: 400;\">Cymbalta<\/span><\/a><span style=\"font-weight: 400;\"> (duloxetine),<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/lexapro\"><span style=\"font-weight: 400;\">Lexapro<\/span><\/a><span style=\"font-weight: 400;\"> (escitalopram), and<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/effexor-xr\"><span style=\"font-weight: 400;\">Effexor<\/span><\/a><span style=\"font-weight: 400;\"> (venlafaxine).\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/zoloft-during-pregnancy\/\"><b>Is it safe to take Zoloft during pregnancy?<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">You should always discuss the risks and benefits with your doctor regarding any of these medications while pregnant or during the postpartum period.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pregnancy expands your health considerations to include your growing baby. That\u2019s why finding a pregnancy-safe medication to treat depression and anxiety is a top priority for many expectant parents\u2014 especially since several drugs, including antidepressants, pose some risk to mother and baby during pregnancy. But when you consider that 1 in 7 women experience a [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":18689,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[8970,788,8615],"coauthors":[20330],"class_list":["post-19290","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-breastfeeding","tag-drug-safety","tag-pregnancy","franchise-maternal-matters","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Prozac and pregnancy: Is it safe to take Prozac while pregnant?<\/title>\n<meta name=\"description\" content=\"There are risks when mixing Prozac and pregnancy, but the impact of untreated depression may be greater. 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