{"id":27277,"date":"2021-04-22T13:00:33","date_gmt":"2021-04-22T17:00:33","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=27277"},"modified":"2021-04-12T16:19:57","modified_gmt":"2021-04-12T20:19:57","slug":"neurontin-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/neurontin-side-effects\/","title":{"rendered":"Neurontin side effects and how to avoid them"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#neurontin-side-effects\">Neurontin side effects<\/a> | <a href=\"#how-long-do-side-effects-last\">How long do side effects last?<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Neurontin is a brand-name prescription medicine for the generic drug gabapentin. It is FDA approved to prevent and control seizures in adults and children with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/epilepsy-treatment-and-medications\"><span style=\"font-weight: 400;\">epilepsy<\/span><\/a><span style=\"font-weight: 400;\"> and to treat postherpetic neuralgia, which is nerve pain caused by <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/shingles-treatment-and-medications\"><span style=\"font-weight: 400;\">shingles<\/span><\/a><span style=\"font-weight: 400;\"> (herpes zoster). It is also sometimes prescribed to treat other kinds of <a href=\"https:\/\/www.singlecare.com\/conditions\/neuropathy-treatment-and-medications\">neuropathy<\/a><\/span><span style=\"font-weight: 400;\">, <a href=\"https:\/\/www.singlecare.com\/conditions\/fibromyalgia-treatment-and-medications\">fibromyalgia<\/a>, and alcohol withdrawal.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like any other medication, it is important to be aware of side effects and other drug interactions. Let&#8217;s look at what you should know before taking Neurontin.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/neurontin\/what-is\"><b>What is Neurontin?<\/b><\/a><b> | <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/neurontin\"><b>Free Neurontin discounts<\/b><\/a><\/p>\n<h2 id=\"neurontin-side-effects\"><span style=\"font-weight: 400;\">Common side effects of Neurontin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like all medications, Neurontin may cause minor and temporary side effects. According to the manufacturer, the <\/span><a href=\"http:\/\/labeling.pfizer.com\/ShowLabeling.aspx?id=630\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">most common side effects<\/span><\/a><span style=\"font-weight: 400;\"> include:\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Fatigue, drowsiness, or somnolence (sleepiness)<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Dizziness\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Nystagmus, or involuntary eye movements\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Lack of coordination<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Swelling in legs and feet<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Viral infection (children)<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Nausea and vomiting (children)<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Hostility (children)<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Other possible side effects<\/span><\/h3>\n<p><a href=\"https:\/\/online.epocrates.com\/drugs\/102205\/Neurontin\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Additional adverse effects<\/span><\/a><span style=\"font-weight: 400;\"> may include:\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Double or decreased vision<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Infection<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Asthenia, or weakness<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Abnormal thinking<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Impotence<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Amnesia or memory loss<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Trouble speaking<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Upset stomach<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Back pain<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Hyperactivity (children)<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Serious side effects of Neurontin<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some side effects of Neurontin are more serious and may require medical attention. These include:\u00a0<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Depression, unusual moods or behaviors<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Suicidal thoughts or thoughts of hurting yourself<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Anaphylaxis, a life-threatening allergic reaction<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Angioedema, swelling beneath the skin from an allergic reaction<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Slow, shallow, or difficult breathing<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Serious or unusual skin rash<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Seizures or serious side effects when the drug is stopped quickly<\/span><\/li>\n<\/ul>\n<h2 id=\"how-long-do-side-effects-last\"><span style=\"font-weight: 400;\">How long do Neurontin side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some side effects, such as dizziness and drowsiness, are more likely to occur when you first start taking the drug. Most side effects are temporary and will lessen over a period of days and weeks as the body adjusts to the medication.\u00a0<\/span><\/p>\n<h2 id=\"warnings\"><span style=\"font-weight: 400;\">Neurontin contraindications and warnings<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Neurontin has a relatively low risk for physical addiction, but it may create a psychological dependence in some people. According to <\/span><a href=\"https:\/\/www.pfizermedicalinformation.com\/en-us\/patient\/neurontin?tab=pi&amp;section=description\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Pfizer,<\/span><\/a><span style=\"font-weight: 400;\"> most people who misuse Neurontin have a history of drug abuse so it is important for patients to tell their healthcare provider about any past drug use. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27265421\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Studies<\/span><\/a><span style=\"font-weight: 400;\"> show that that the incidence of misuse was only in 1% of the population taking it, and that the primary reason was for recreational purposes or intentional self-harm.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The effects of Neurontin (gabapentin) may range from an elevated mood or euphoria to a sense of calm or relaxation. These effects are amplified when taken with other substances such as alcohol or opioids like heroin, fentanyl, and prescription painkillers, and are more lethal when taken in combination. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-and-alcohol\/\"><span style=\"font-weight: 400;\">Gabapentin and alcohol<\/span><\/a><span style=\"font-weight: 400;\"> each cause central nervous system (CNS) depression and respiratory depression. Combining alcohol and gabapentin can worsen either or both effects. Patients should not drink alcohol or consume marijuana while taking Neurontin.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Withdrawal<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Patients should not stop taking Neurontin without talking with their healthcare provider, and abrupt cessation of Neurontin is not recommended. Slowly titrating the dose down can help reduce the risk of withdrawal symptoms.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Withdrawal symptoms of Neurontin include anxiety, difficulty falling asleep or staying asleep, nausea, pain, and sweating. People taking Neurontin who experience worsening of these symptoms should seek medical attention. A <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2000\/21216lbl.pdf\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">placebo-controlled study<\/span><\/a><span style=\"font-weight: 400;\"> showed that abruptly discontinuing the use of Neurontin and other anti-epileptic drugs leads to the possibility of increasing seizure frequency, even if Neurontin is not being used to treat seizures.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The half-life of Neurontin is relatively short, generally between five and seven hours. While everyone reacts to Neurontin differently, for most people, withdrawal symptoms begin about 12 hours after the last dose is taken. Common withdrawal symptoms include anxiety, irritability, fatigue, headache, dizziness, nausea, abdominal pain, and seizures. Stopping the medication too quickly may cause seizures to worsen or cause a different kind of seizure.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The typical recommended adult daily dosage of Neurontin is 1,800 mg, although some patients are prescribed up to 3,600 mg per day. Since everyone responds to medication differently, it is possible for individuals to overdose on smaller amounts. Patients should not take a larger dose of Neurontin than prescribed by their doctor or pharmacist. Symptoms of overdose included double vision, tremor, slurred speech, drowsiness, altered mental status, dizziness, lethargy, and diarrhea. According to <\/span><a href=\"https:\/\/www.pfizermedicalinformation.com\/en-us\/patient\/neurontin?tab=pi&amp;section=overdose\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Pfizer<\/span><\/a><span style=\"font-weight: 400;\">, fatal respiratory depression has been reported in individuals who have overdosed on Neurontin. Patients should seek medical advice right away if they have pale or blue lips, fingernails, or skin, difficult or troubled breathing, or irregular, fast, slow, or shallow breathing, as these are all signs of respiratory depression.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Restrictions<\/span><\/h3>\n<ul>\n<li><span style=\"font-weight: 400;\">Patients should tell their healthcare provider if they have a history of depression, suicidal thoughts, or drug abuse. Anti-epileptic drugs (AEDs), including Neurontin, may increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication. Patients treated with any AED for any indication should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and any unusual changes in mood or behavior.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">People with a history of lung problems or breathing disorders should consult their healthcare professional before taking Neurontin. Gabapentin can cause life-threatening breathing problems, especially in older adults or people with chronic obstructive pulmonary disease (COPD). Patients who experience shallow or slow breathing, vomiting, or abnormal breath sounds should seek medical attention as these are signs of respiratory depression, a potentially fatal condition.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Seniors, children, people with certain medical conditions such as liver or kidney problems, heart disease, diabetes, and seizures are more at risk of developing a wider range of side effects.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">In seniors, there is an increased risk of dizziness, which can lead to falls.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">People who have had an allergic reaction to gabapentin in the past should not take it. Patients should seek medical help if they experience signs of a serious allergic reaction such as hives, swelling in the face, lips, or tongue, or sudden weakness, confusion, nausea, or vomiting.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">People should not drive or operate heavy machinery until they know how Neurontin affects them.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">The risks and benefits of taking Neurontin and all AEDs need to be carefully considered for pregnant and breastfeeding patients. Notify your healthcare provider if you are pregnant, breastfeeding, or think you may become pregnant before taking Neurontin.<\/span><\/li>\n<\/ul>\n<h2 id=\"interactions\"><span style=\"font-weight: 400;\">Neurontin interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Neurontin is an anti-epileptic drug (AED), also called an anticonvulsant. It affects chemicals and nerves in the body and suppresses the excessive rapid firing of neurons during seizures. Neurontin can be used in combination with other commonly used antiepileptic drugs, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/gralise\"><span style=\"font-weight: 400;\">Gralise<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The risk of serious side effects, such as shallow breathing and severe drowsiness, may be increased if this medication is taken with <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/102204\/Neurontin\/Drug-Interactions\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">other products<\/span><\/a><span style=\"font-weight: 400;\"> that cause drowsiness or breathing problems. Do not combine Neurontin with:<\/span><\/p>\n<ul>\n<li><b>Antidepressants and anxiolytics<\/b><span style=\"font-weight: 400;\">, including bupropion<\/span><\/li>\n<li><b>Antiemetics<\/b><span style=\"font-weight: 400;\">, including metoclopramide\u00a0\u00a0<\/span><\/li>\n<li><b>Antihistamines,<\/b><span style=\"font-weight: 400;\"> sedatives, or anything else that will make you drowsy\u00a0<\/span><\/li>\n<li><b>Alcohol and marijuana, <\/b><span style=\"font-weight: 400;\">which may increase the risk of CNS and respiratory depression and psychomotor impairment\u00a0<\/span><\/li>\n<li><b>CNS Depressants<\/b>\u2014<span style=\"font-weight: 400;\">according to the <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-warns-about-serious-breathing-problems-seizure-and-nerve-pain-medicines-gabapentin-neurontin\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Food and Drug Administration<\/span><\/a><span style=\"font-weight: 400;\">, people who have respiratory risk factors may have trouble breathing when taking Neurontin combined with CNS depressants<\/span><\/li>\n<li><b>Immunosuppressants<\/b><span style=\"font-weight: 400;\">, including muromonab-CD3<\/span><\/li>\n<li><b>Multiple sclerosis agents<\/b><span style=\"font-weight: 400;\">, including dalfampridine and amifampridine\u00a0<\/span><\/li>\n<li><b>Opioid medications<\/b><span style=\"font-weight: 400;\">, such as hydrocodone, can increase the risk of respiratory depression<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Antacids containing aluminum or magnesium may interfere with the absorption of this medication. Therefore, if you are also taking an antacid, it is best to take gabapentin at least two hours after taking the antacid.<\/span><\/p>\n<h2 id=\"how-to-avoid-side-effects\"><span style=\"font-weight: 400;\">How to avoid Neurontin side effects<\/span><\/h2>\n<h3><span style=\"font-weight: 400;\">1. Take Neurontin as prescribed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Neurontin is available as a capsule, tablet, extended-release tablet, and oral solution. It can be taken by mouth with or without food.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For patients 12 years of age and older, the starting dosage is 300 mg three times a day, and the maintenance dose is typically 300 to 600 mg three times a day. During the first few days of treatment, your doctor may gradually increase your dose so your body can adjust to the medication. In general, dose selection for older patients should be cautious, usually starting at the low end of the dosing range. Dosage for children younger than 12 is based on weight.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/gabapentin-dosage\/\"><b>See gabapentin dosages<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">The time between doses should not exceed 12 hours. Take a missed dose as soon as possible. Do not take extra medicine to make up for a missed dose. If you have epilepsy, do not allow more than 12 hours to pass between doses.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2. Discuss your full medical history with your healthcare provider<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tell your doctor of any medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. Let them know if you are pregnant or breastfeeding. Tell your provider if you have a history of kidney or lung disease. It&#8217;s also important to discuss a history of depression or mental health issues and if you&#8217;ve ever experienced suicidal ideation, as Neurontin may increase these thoughts.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3. Monitor effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Neurontin may cause dizziness and tiredness. Tell your provider if you use anything else that makes you sleepy, such as allergy medicine, narcotic pain medicine, and alcohol. Do not use more than the recommended dose of gabapentin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Make sure to get plenty of rest and stick to a regular sleep routine.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Avoid alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Alcohol and anticonvulsants both slow brain activity and can cause drowsiness, dizziness, and difficulty concentrating. Taking these together can worsen these effects, making you feel extra drowsy and dizzy with the potential for impaired thinking. There is also an increased risk of seizures with excess alcohol use or alcohol withdrawal. Therefore, you should not take alcohol while taking Neurontin. Talk to a healthcare professional if you have any questions or concerns.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Neurontin side effects | How long do side effects last? | Warnings | Interactions | How to avoid side effects Neurontin is a brand-name prescription medicine for the generic drug gabapentin. It is FDA approved to prevent and control seizures in adults and children with epilepsy and to treat postherpetic neuralgia, which is nerve pain [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":27290,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12752],"coauthors":[8861],"class_list":["post-27277","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Neurontin side effects and how to avoid them | SingleCare<\/title>\n<meta name=\"description\" content=\"Drowsiness, dizziness, and fatigue are common Neurontin side effects. 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