{"id":29040,"date":"2021-04-26T13:42:18","date_gmt":"2021-04-26T17:42:18","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=29040"},"modified":"2021-05-13T12:36:30","modified_gmt":"2021-05-13T16:36:30","slug":"sumatriptan-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/sumatriptan-side-effects\/","title":{"rendered":"Sumatriptan side effects and how to avoid them"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#sumatriptan-side-effects\">Sumatriptan side effects<\/a> | <a href=\"#serious-side-effects\">Serious side effects <\/a>| <a href=\"#how-long-do-side-effects-last\">How long do side effects last?<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sumatriptan succinate is a generic prescription drug used for the treatment of acute migraine and cluster headaches. Migraine symptoms are due to the widening of blood vessels in the head when the trigeminal nerve is overstimulated. Drugs like sumatriptan, known as triptans or 5HT receptor agonists, relieve migraine symptoms by tightening blood vessels in the head.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many people achieve significant relief from migraine symptoms using sumatriptan in its various formats, but this medication is not right for everyone. Side effects can sometimes be serious, and sumatriptan can worsen underlying medical conditions or interact with other medications being taken.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/sumatriptan\/what-is\"><b>Learn more about sumatriptan<\/b><\/a><\/p>\n<h2 id=\"sumatriptan-side-effects\"><span style=\"font-weight: 400;\">Common side effects of sumatriptan<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like all drugs, sumatriptan can produce unwanted side effects. The most likely adverse effects will depend on how sumatriptan is taken: as a tablet, nasal spray, nasal powder, or subcutaneous injection. Side effects <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/168010\/sumatriptan\/Monograph\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">common to all formats<\/span><\/a><span style=\"font-weight: 400;\"> of sumatriptan include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual sensations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Burning or prickling feeling in the hands or feet<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hot or cold sensation on the skin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Neck, throat, or jaw pain\/tightness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain or tightness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feeling of heaviness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In addition, <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4e26764d-ce26-e5ac-e6db-0f1f7a1d5c2b\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">sumatriptan injections<\/span><\/a><span style=\"font-weight: 400;\"> may also commonly cause side effects such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness or vertigo\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flushing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Injection site reactions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">When taken as a nasal spray or powder, sumatriptan produces very common additional side effects:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bad or unusual taste<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal passage discomfort<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Runny nose or nasal congestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness or vertigo<\/span><\/li>\n<\/ul>\n<h2 id=\"serious-side-effects\"><span style=\"font-weight: 400;\">Serious side effects of sumatriptan<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because sumatriptan tightens blood vessels, it can produce serious and even life-threatening adverse effects involving the heart and blood vessels, as well as the body systems they support. Many serious side effects are due to the overtightening of blood vessels, called vasospasms. Sumatriptan\u2019s most serious side effects include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/a><span style=\"font-weight: 400;\"> including hypertensive crisis (blood pressure greater than 180\/120 mmHg)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Spasms of the heart\u2019s blood supply (coronary artery vasospasm or Prinzmetal\u2019s angina)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Serious heart problems such as:\u00a0<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Ventricular tachycardia (speeding up of the ventricular heartbeats)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Ventricular fibrillation (highly irregular ventricular heartbeats)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Arrhythmias (irregular heartbeats)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Heart tissue death (myocardial ischemia)<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cerebrovascular problems such as:<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Bleeding in the brain (cerebral hemorrhage or subarachnoid hemorrhage)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><a href=\"https:\/\/www.singlecare.com\/blog\/signs-of-a-stroke\/\"><span style=\"font-weight: 400;\">Stroke<\/span><\/a><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood vessel problems such as:<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Death of tissues due to blockage of the arteries to the limbs (peripheral vascular ischemia), digestive system (intestinal ischemia), or spleen (splenic infarction)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Vision loss or blindness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><a href=\"https:\/\/www.singlecare.com\/conditions\/raynauds-treatment-and-medications\"><span style=\"font-weight: 400;\">Raynaud\u2019s syndrome<\/span><\/a><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Serotonin syndrome<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medication-overuse headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions including anaphylaxis and angioedema<\/span><\/li>\n<\/ul>\n<h2 id=\"how-long-do-side-effects-last\"><span style=\"font-weight: 400;\">How long do sumatriptan side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Sumatriptan is a short-acting medication with a half-life of around <\/span><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Sumatriptan\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">two hours<\/span><\/a><span style=\"font-weight: 400;\">. A sumatriptan dose will be completely cleared from the body in 10 hours. Minor side effects will typically fade by then. Some side effects, such as serotonin syndrome or medication-overuse headache, will require sumatriptan to be discontinued at least temporarily. Recovery may take a few days. More serious side effects caused by vascular problems, such as stroke, heart attack, or tissue death (ischemia), may result in chronic or even lifelong medical conditions.<\/span><\/p>\n<h2 id=\"warnings\"><span style=\"font-weight: 400;\">Sumatriptan contraindications &amp; warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Sumatriptan does not cause physical or psychological dependence. However, overusing sumatriptan or any headache medication can produce medication-overuse headache (MOH), a condition in which <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538150\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">headaches increase in frequency and intensity<\/span><\/a><span style=\"font-weight: 400;\">, producing a vicious cycle of medication overuse followed by more rebound headaches.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Taking more than the recommended dose should always be avoided. Sumatriptan narrows blood vessels, so an overdose could cause tremors, reduced breathing, loss of coordination, vision problems, or seizures. Treatment for overdose consists of monitoring and observation for at least 10 hours.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Sumatriptan has significant and sometimes dramatic effects on blood vessels, so many people may not be able to take the medication, including children 17 years or younger. People older than 65, however, can take sumatriptan at normal doses, as can people with kidney problems (renal impairment) or with mild to moderate liver problems (hepatic impairment).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People exhibiting risk factors for heart disease such as high blood pressure, high cholesterol, diabetes, excess weight, smoking habit, or a family history of heart disease should not be given sumatriptan until a complete heart examination has determined the heart is healthy. Pregnancy, breastfeeding, and any history of seizures are also reasons to be cautious about taking sumatriptan.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because of potentially dangerous side effects, sumatriptan can never be taken by people with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart problems or a history of heart problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of cerebrovascular problems (stroke) including transient ischemic attacks (TIA)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Narrowing of blood vessels to the arms, legs, kidneys, or stomach (peripheral vascular disease)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uncontrolled hypertension (high blood pressure)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hemiplegic migraines or migraines with brainstem aura (basilar migraines)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ischemic bowel disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypersensitivity to the drug<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">A doctor can help identify if migraines are hemiplegic migraines or migraines with brainstem aura. It was once believed that these migraines were caused by a narrowing of arteries, so triptans, which narrow arteries even more, are avoided as a treatment for these types of migraines.\u00a0<\/span><\/p>\n<h2 id=\"interactions\"><span style=\"font-weight: 400;\">Sumatriptan interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Combining sumatriptan with certain types of drugs can cause side effects, some potentially life-threatening, such as high blood pressure, blood vessel contractions (vasospasms), or serotonin syndrome.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because of the risk for hazardous drug interactions, sumatriptan is never taken with:<\/span><\/p>\n<ul>\n<li><b>MAO inhibitors<\/b><span style=\"font-weight: 400;\"> (MAOIs) such as Marplan (isocarboxazid), phenelzine, tranylcypromine, linezolid, isoniazid, procarbazine, and selegiline\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Other <\/span><b>triptans<\/b><span style=\"font-weight: 400;\"> such as naratriptan, almotriptan, rizatriptan, zolmitriptan, eletriptan, or frovatriptan<\/span><\/li>\n<li><b>Ergot migraine drugs<\/b><span style=\"font-weight: 400;\"> such as ergotamine, dihydroergotamine, methysergide, or methylergonovine<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Because of potential side effects, combining sumatriptan with other common prescription or over-the-counter drugs may require caution:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Serotonergic drugs:<\/b><span style=\"font-weight: 400;\"> Drugs like sumatriptan that raise serotonin levels in the brain are called serotonergic drugs. Too much serotonin, though, can be detrimental and lead to <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/serotonin-syndrome-treatment-and-medications\"><span style=\"font-weight: 400;\">serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\">. This condition can range from a barely noticeable problem to a life-threatening one. Triptans taken by themselves only rarely cause serotonin syndrome. However, combining two or more serotonergic drugs can significantly raise the risk of serotonin syndrome. Serotonergic drugs that should be avoided when taking sumatriptan include antidepressants, antipsychotic medications, bipolar disorder medications, amphetamines, opioid pain relievers, seizure medications, some cough medicines, and drugs that treat the symptoms of Parkinson\u2019s disease.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Ergot derivatives:<\/b><span style=\"font-weight: 400;\"> Sumatriptan should never be combined with ergot drugs, but several types of drugs are ergot derivatives and may need to be avoided. As with serotonergic drugs, combining sumatriptan with ergot derivatives raises the risk of serotonin syndrome as well as depression or loss of coordination.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Stimulants:<\/b><span style=\"font-weight: 400;\"> Sumatriptan causes blood vessels to narrow, raising blood pressure. In fact, sumatriptan taken all by itself can produce hypertensive crisis, a medical emergency in which blood pressure is raised too high. For this reason, it is not a good idea to combine sumatriptan with stimulants. Drugs such as<\/span> <span style=\"font-weight: 400;\">amphetamines, wakefulness agents, ADHD medications, nasal decongestants, bronchodilators, and appetite suppressants also raise blood pressure, so the combination could be hazardous. Also, people are advised not to overdo common stimulants such as caffeine on the days they take a dose of sumatriptan.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Other drugs that raise blood pressure<\/b><span style=\"font-weight: 400;\">: Other drugs that raise blood pressure should also be avoided or taken with caution. These include NSAIDs, birth control pills, sympathomimetic drugs (such as epinephrine), and weight loss medications.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Blood pressure medications: <\/b><span style=\"font-weight: 400;\">Because sumatriptan raises blood pressure, the effectiveness of blood-pressure-lowering drugs will be compromised when taking sumatriptan.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Depressants: <\/b><span style=\"font-weight: 400;\">Sumatriptan can cause side effects such as drowsiness, dizziness, or loss of coordination. This can be a serious problem when driving or engaging in hazardous activities. Drug impairment can be worsened when sumatriptan is combined with depressants such as alcohol, sedatives, benzodiazepines, barbiturates, and seizure medications.<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-avoid-side-effects\"><span style=\"font-weight: 400;\">How to avoid sumatriptan side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Sumatriptan can effectively end migraine attacks in many people, but side effects are always a risk. There are, however, a few practical guidelines that can help minimize the likelihood of adverse effects while helping to maximize the benefits of sumatriptan.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">1. Tell the doctor about all medical conditions and medications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Before sumatriptan is prescribed, tell the prescribing doctor or healthcare professional about:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any current medical conditions, particularly heart problems, circulation problems, high blood pressure, high cholesterol, diabetes, kidney problems, or liver problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any history of seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any family history of heart problems or stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy, nursing, or any pregnancy plans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Smoking<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">All prescription and over-the-counter medications, supplements, and herbal remedies being taken, particularly monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, SSRIs (selective serotonin reuptake inhibitors), or SNRIs (selective serotonin and norepinephrine reuptake inhibitors)<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">2. Take sumatriptan as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Take the dose as prescribed. Do not increase or change the dose. Above all, do not take more than two doses in a single 24-hour period. If the first dose doesn\u2019t work at all, do not take a second dose until consulting a doctor or other healthcare professional. There is a possibility that the symptoms are not being caused by a migraine.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3. Understand the dosing instructions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Make sure to understand and master the instructions for taking a sumatriptan dose. While it\u2019s relatively easy to take sumatriptan tablets, other formats can be a bit more complex or confusing to take. When sumatriptan is first prescribed, a healthcare provider will most likely demonstrate the proper way to take a dose. Sometimes patients will take the first dose in the office under the supervision of a healthcare professional. Even with a demonstration, it\u2019s always a good idea to review the detailed and often illustrated instructions that come with the medicine regularly to make sure it\u2019s being taken correctly.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Take a sumatriptan dose as soon as symptoms begin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Sumatriptan can be taken at any time when <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/migraine-treatment-and-medications\"><span style=\"font-weight: 400;\">migraine symptoms<\/span><\/a><span style=\"font-weight: 400;\"> are experienced, but it is most effective at warding off symptoms when taken near the onset of symptoms.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">5. Do not take sumatriptan or other migraine medications more than 10 times a month<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People who use sumatriptan and other prescription or over-the-counter migraine medications 10 or more times per month are at risk for medication-overuse headaches. If four or more headaches are experienced each month, seek medical advice from a doctor or other healthcare professional before taking too much medication.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">6. Avoid risky or complex activities<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Sumatriptan can cause drowsiness and affect coordination. When first taking sumatriptan, avoid driving or activities that are risky or require focus. Once certain that sumatriptan is not causing impairment, engage in those activities cautiously whenever a dose has been taken. Avoid alcohol or any medication that causes drowsiness or impairment after taking a dose of sumatriptan.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">7. Avoid overtaking stimulants<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To lower the risk of high blood pressure, don\u2019t overtake stimulants such as caffeine when a dose of sumatriptan has been taken.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Resources:<\/span><\/h2>\n<ul>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=584abe73-8290-4484-ff8e-5890831c095e\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Imitrex tablets prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK538150\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Medication-overuse headache<\/span><\/a><span style=\"font-weight: 400;\">, StatPearls<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=a8a9889e-69b9-4a57-b8c0-d40b1025c559\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Onzetra Xsail prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/online.epocrates.com\/drugs\/168010\/sumatriptan\/Monograph\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Sumatriptan<\/span><\/a><span style=\"font-weight: 400;\">, Epocrates<\/span><\/li>\n<li><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/Sumatriptan\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Sumatriptan compound information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=6d521807-e5ce-498d-a224-5534c5ea61fa\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Sumatriptan nasal spray prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4e26764d-ce26-e5ac-e6db-0f1f7a1d5c2b\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-weight: 400;\">Sumatriptan succinate injection 6 mg prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Sumatriptan side effects | Serious side effects | How long do side effects last? | Warnings | Interactions | How to avoid side effects Sumatriptan succinate is a generic prescription drug used for the treatment of acute migraine and cluster headaches. Migraine symptoms are due to the widening of blood vessels in the head when [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":29063,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12752,4316],"coauthors":[8861],"class_list":["post-29040","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-medication-side-effects","tag-migraine","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Sumatriptan side effects and safety information | SingleCare<\/title>\n<meta name=\"description\" content=\"Fatigue, chest pain, and burning in hands or feet are common sumatriptan side effects. 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