{"id":2923,"date":"2018-07-30T22:43:04","date_gmt":"2018-07-31T02:43:04","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=2923"},"modified":"2025-10-07T13:15:59","modified_gmt":"2025-10-07T17:15:59","slug":"eliquis-vs-xarelto","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/eliquis-vs-xarelto\/","title":{"rendered":"Xarelto vs. Eliquis: Which is better for blood clots?"},"content":{"rendered":"

Eliquis and Xarelto are two brand-name medications used to prevent and treat various clotting disorders. Both drugs are oral anticoagulants and are subclassified as NOACs (novel oral anticoagulants) or DOACs (direct oral anticoagulants), based on their direct inhibition of the clotting protein <\/span>factor Xa<\/span><\/a>. Unlike Coumadin (warfarin), an older anticoagulant medication, patients taking Eliquis or Xarelto do not need regular blood tests to monitor levels. This convenience and their consistent blood-thinning action have made them popular amongst patients and healthcare providers. When choosing between Eliquis and Xarelto, the medical advice of your healthcare team is critical, but it can be helpful to enter into the conversation with more background knowledge.<\/span><\/p>\n

RELATED: <\/b>Are new blood thinners better than Coumadin (warfarin)?<\/b><\/a><\/p>\n

What are the main differences between Eliquis and Xarelto?<\/span><\/h2>\n

Brand-name versions are typically the only option for Eliquis and Xarelto. Generic rivaroxaban is available as a 2.5 mg tablet only. Otherwise, no generic is available yet for either drug; however, a <\/span>generic Eliquis<\/span><\/a> is expected to be available in April 2028. Eliquis is made by Bristol-Myers Squibb in tablet form only, whereas Xarelto is made by Janssen Pharmaceuticals in both tablet and liquid suspension form. Both drugs are used by adults, but Xarelto is also used in children. Regardless of which DOAC is used, dosages vary by indication.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Main differences between Xarelto vs. Eliquis<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n

<\/td>\nXarelto<\/b><\/td>\nEliquis<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nFactor Xa inhibitor<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nBrand (except 2.5 mg rivaroxaban tablets)<\/span><\/td>\n<\/tr>\n
What is the active ingredient?<\/b><\/td>\nRivaroxaban<\/span><\/td>\nApixaban<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nTablet, starter pack, oral suspension<\/span><\/td>\nTablet, starter pack<\/span><\/td>\n<\/tr>\n
What is the standard dosage?<\/b><\/td>\nAdults: 2.5 mg to 15 mg twice daily or 10 mg to 20 mg once daily<\/span><\/p>\n

Dosage varies by indication<\/span><\/p>\n

Children: Dosage varies by weight and indication<\/span><\/td>\n

2.5 mg to 10 mg twice a day<\/span><\/p>\n

Dosage varies by indication<\/span><\/td>\n<\/tr>\n

How long is the typical treatment?<\/b><\/td>\nVaries<\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nAdults and children<\/span><\/td>\nAdults<\/span><\/td>\n<\/tr>\n
More information<\/b><\/td>\nWhat is Xarelto?<\/span><\/a><\/td>\nWhat is Eliquis?<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Conditions treated by Xarelto and Eliquis<\/span><\/h2>\n

According to their drug labels, <\/span>Eliquis<\/span><\/a> and <\/span>Xarelto<\/span><\/a> have several indications that are the same\u2014to reduce the risk of stroke and embolism in patients with nonvalvular atrial fibrillation (AFib, or irregular heartbeat), prevent deep vein thrombosis (DVT) in patients who have had hip or knee replacement, treat DVT, treat pulmonary embolism (PE), and to reduce the risk of recurrent DVT or PE following initial therapy. Both of the drugs are indicated for the following health conditions:<\/span><\/p>\n