{"id":3342,"date":"2018-12-05T15:51:36","date_gmt":"2018-12-05T20:51:36","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=3342"},"modified":"2022-11-30T13:51:54","modified_gmt":"2022-11-30T18:51:54","slug":"celexa-vs-zoloft","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/celexa-vs-zoloft\/","title":{"rendered":"Celexa vs. Zoloft: Differences, similarities, and which is better for you"},"content":{"rendered":"

Drug overview & main differences<\/a> | Conditions treated<\/a> | Efficacy<\/a> | Insurance coverage and cost comparison<\/a> | Side effects<\/a> | Drug interactions<\/a> | Warnings<\/a> | FAQ<\/a><\/p>\n

Celexa<\/span> and <\/span>Zoloft<\/span> are two prescription medications used in the treatment of major depression disorder (MDD), sometimes simply referred to as depression. Depression is one of the most prevalent <\/span>mental health conditions<\/span> in the United States, and it is characterized by prolonged (2 weeks or more) feelings of low mood and decreased energy levels. Patients may not find joy in things they enjoyed previously. The Anxiety and Depression Association of America (<\/span>ADAA<\/span><\/a>) estimate that over 20% of adults in the United States will develop MDD at some point in their life. <\/span>Mental health conditions<\/span> are not always adequately treated or treated at all. Many factors contribute to that trend including an inability to recognize signs and symptoms and stereotypes about the conditions. <\/span>Celexa<\/span> (citalopram) and <\/span>Zoloft<\/span> (<\/span>sertraline<\/span>) are two <\/span>antidepressant medications<\/span> that treat the symptoms of depression.<\/span><\/p>\n

What are the main differences between Celexa and Zoloft?<\/h2>\n

Celexa<\/span><\/a> is a prescription medication indicated in the <\/span>treatment of depression<\/span>. It belongs to a class of drugs known as <\/span>selective serotonin reuptake inhibitors<\/span> (<\/span>SSRIs<\/span><\/a>) and is available generically as citalopram. Neurotransmitters like serotonin move between neurons via selective pumps. <\/span>Celexa<\/span> blocks the reuptake of serotonin by the pump. By blocking serotonin reuptake by the transport pump, the drug is effectively leaving more free serotonin in the neuron synapse. Higher levels of serotonin are associated with improved mood and energy levels. The active ingredient, <\/span>citalopram<\/span><\/a>, has two isomers in its formulation, R-citalopram and S-citalopram. The S-isomer is primarily responsible for the serotonin blockade that makes citalopram effective. Another <\/span>SSRI<\/span>, <\/span>Lexapro<\/span><\/a> (<\/span>escitalopram<\/span>), is composed only of the S-isomer of citalopram.<\/span><\/p>\n

Celexa<\/span> is available in an oral tablet formulation in strengths of 10 mg, 20 mg, and 40 mg. It is also available in an oral liquid solution in concentrations of 10 mg\/5 ml and 20 mg\/5 ml.<\/span><\/p>\n

Zoloft<\/span><\/a>\u00a0 (<\/span>sertraline<\/span>) is also a prescription medication in the <\/span>SSRI<\/span> class indicated in the <\/span>treatment of depression<\/span>. <\/span>Zoloft<\/span> also works by blocking the reuptake of only serotonin at the neuronal synapse. Other <\/span>SSRIs<\/span> you may be familiar with include <\/span>Prozac<\/span><\/a> (<\/span>fluoxetine<\/span>), and <\/span>Paxil<\/span><\/a> (<\/span>paroxetine<\/span>).\u00a0<\/span><\/p>\n

Zoloft<\/span> is available as an oral tablet in strengths of 25 mg, 50 mg, and 100mg. It is also available in an oral concentrated solution that is 20 mg\/ ml.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
Main differences between Celexa and Zoloft <\/span><\/th>\n<\/tr>\n<\/thead>\n
<\/td>\nCelexa<\/b><\/td>\nZoloft<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nSelective serotonin reuptake inhibitor<\/span><\/td>\nSelective serotonin reuptake inhibitor<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nBrand and generic available<\/span><\/td>\nBrand and generic available<\/span><\/td>\n<\/tr>\n
What is the generic name?<\/b><\/td>\nCitalopram<\/span><\/td>\nSertraline<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nOral tablet and oral solution<\/span><\/td>\nOral tablets and solution<\/span><\/td>\n<\/tr>\n
What is the standard dosage?<\/b><\/td>\n20 mg once per day<\/span><\/td>\n50 mg once per day<\/span><\/td>\n<\/tr>\n
How long is the typical treatment?<\/b><\/td>\nLong-term (months to years)<\/span><\/td>\nLong-term (months to years)<\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nAdolescents and adults<\/span><\/td>\nChildren, adolescents, and adults<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Conditions treated by Celexa and Zoloft<\/h2>\n

Celexa<\/span> and <\/span>Zoloft<\/span> are each <\/span>Food and Drug Administration<\/span> (<\/span>FDA<\/span>) approved to treat <\/span>major depressive disorder<\/span>. They also each have some unique indications for use. <\/span>Zoloft<\/span> is approved by the <\/span>FDA<\/span>) in the treatment of <\/span>social anxiety disorder<\/span> and <\/span>obsessive-compulsive disorder<\/span> (<\/span>OCD<\/span><\/a>). Both <\/span>Celexa<\/span> and <\/span>Zoloft<\/span> are used <\/span>off-label<\/span> in <\/span>generalized anxiety disorder<\/span> (GAD), <\/span>panic disorder<\/span>, and premature <\/span>ejaculation<\/span>.\u00a0\u00a0<\/span><\/p>\n

This table of indications is for informational purposes only and is not meant to be official <\/span>medical advice<\/span>. Please visit your <\/span>healthcare<\/span> professional to determine which treatment is best for your condition.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Condition<\/b><\/td>\nCelexa<\/b><\/td>\nZoloft<\/b><\/td>\n<\/tr>\n
Major depressive disorder<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Aggression disorder (dementia associated)<\/span><\/td>\nOff-label<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Binge eating disorder<\/span><\/td>\nOff-label<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Generalized anxiety disorder<\/span><\/td>\nOff-label<\/span><\/td>\nOff-label<\/span><\/td>\n<\/tr>\n
Obsessive-compulsive disorder<\/span><\/td>\nOff-label<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Panic disorder<\/span><\/td>\nOff-label<\/span><\/td>\nOff-label<\/span><\/td>\n<\/tr>\n
Posttraumatic stress disorder<\/span><\/td>\nOff-label<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Premature <\/span>ejaculation<\/span><\/td>\nOff-label<\/span><\/td>\nOff-label<\/span><\/td>\n<\/tr>\n
Premenstrual dysphoric disorder<\/span><\/td>\nOff-label<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Hot flashes due to menopause<\/span><\/td>\nNo<\/span><\/td>\nOff-label<\/span><\/td>\n<\/tr>\n
Social anxiety disorder<\/span><\/td>\nOff-label<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Separation <\/span>anxiety disorder<\/span><\/td>\nNo<\/span><\/td>\nOff-label<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Is Celexa or Zoloft more effective?<\/h2>\n

Celexa<\/span> and <\/span>Zoloft<\/span> have been studied head to head in <\/span>clinical trials<\/span>. A <\/span>double-blind, randomized trial<\/span><\/a> for a six-week period found both drugs to be effective at treating depression. They also were both tolerated well. However, <\/span>Celexa<\/span> showed earlier signs of symptom improvement, providing relief of depressive symptoms more quickly than <\/span>Zoloft<\/span>. The delay in symptom relief can be a factor in the early discontinuation of therapy because patients don\u2019t realize a benefit fast enough. An earlier onset of relief can be a significant contributing factor to medication compliance. Your <\/span>psychiatry<\/span> professional will help decide what is right for you.<\/span><\/p>\n

Related: Celexa vs. Lexapro<\/a><\/strong><\/p>\n

Coverage and cost comparison of Celexa vs. Zoloft<\/h2>\n

Celexa<\/span> is a prescription medication that is covered by both commercial and Medicare drug insurance plans. The out-of-pocket price of <\/span>Celexa<\/span> can be more than $400 for a one-month supply. With a<\/span> coupon<\/span><\/a> from SingleCare, you could obtain the generic medication for as low as $4.<\/span><\/p>\n

Zoloft<\/span> is also a prescription drug that is generally covered by both Medicare and commercial drug plans. The out-of-pocket price of <\/span>brand-name<\/span> Zoloft<\/span> may be more than $500, but with a coupon from SingleCare, you could pay less than $10 for the <\/span>generic form<\/span><\/a>.<\/span><\/p>\n\n\n\n\n\n\n\n\n
<\/td>\nCelexa<\/b><\/td>\nZoloft<\/b><\/td>\n<\/tr>\n
Typically covered by insurance?<\/b><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Typically covered by Medicare Part D?<\/b><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Quantity<\/b><\/td>\n30, 20 mg tablets<\/span><\/td>\n30, 50mg tablets<\/span><\/td>\n<\/tr>\n
Typical Medicare copay<\/b><\/td>\nLess than $10<\/span><\/td>\nLess than $10<\/span><\/td>\n<\/tr>\n
SingleCare cost<\/b><\/td>\n$4+<\/span><\/td>\n$6+<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Common side effects of Celexa vs. Zoloft<\/h2>\n

Celexa<\/span> and <\/span>Zoloft<\/span> each work by the same mechanism to increase serotonin, and their adverse event profiles are similar as well. Both medications are linked to instances of <\/span>dry mouth<\/span>, nausea, vomiting, diarrhea, and sweating. Somnolence, or excessive <\/span>drowsiness<\/span>, is also a potential <\/span>side effect<\/span> the two <\/span>antidepressants<\/span> share.\u00a0<\/span><\/p>\n

There are some differences that may be important for clinicians to consider. <\/span>Celexa<\/span> is not linked to <\/span>constipation<\/span> or decreased appetite, but <\/span>Zoloft<\/span> is. This would be an important consideration in patients with preexisting treatments or disorders which may also affect the gastrointestinal function of <\/span>your body<\/span> or appetite. Decreased libido (<\/span>sex drive<\/span>) is slightly more common with <\/span>Zoloft<\/span> and is a concern that should be addressed prior to starting therapy with either drug.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\nCelexa<\/b><\/td>\nZoloft<\/b><\/td>\n<\/tr>\n
Side Effect<\/b><\/td>\nApplicable?<\/b><\/td>\nFrequency<\/b><\/td>\nApplicable?<\/b><\/td>\nFrequency<\/b><\/td>\n<\/tr>\n
Nausea<\/span><\/td>\nYes<\/span><\/td>\n21%<\/span><\/td>\nYes<\/span><\/td>\n26%<\/span><\/td>\n<\/tr>\n
Dry mouth<\/span><\/td>\nYes<\/span><\/td>\n20%<\/span><\/td>\nYes<\/span><\/td>\n14%<\/span><\/td>\n<\/tr>\n
Sweating<\/span><\/td>\nYes<\/span><\/td>\n11%<\/span><\/td>\nYes<\/span><\/td>\n7%<\/span><\/td>\n<\/tr>\n
Vomiting<\/span><\/td>\nYes<\/span><\/td>\n4%<\/span><\/td>\nYes<\/span><\/td>\n4%<\/span><\/td>\n<\/tr>\n
Diarrhea<\/span><\/td>\nYes<\/span><\/td>\n8%<\/span><\/td>\nYes<\/span><\/td>\n4%<\/span><\/td>\n<\/tr>\n
Constipation<\/span><\/td>\nNo<\/span><\/td>\nn\/a<\/span><\/td>\nYes<\/span><\/td>\n6%<\/span><\/td>\n<\/tr>\n
Dyspepsia<\/span><\/td>\nYes<\/span><\/td>\n5%<\/span><\/td>\nYes<\/span><\/td>\n8%<\/span><\/td>\n<\/tr>\n
Dizziness<\/span><\/td>\nNo<\/span><\/td>\nn\/a<\/span><\/td>\nYes<\/span><\/td>\n12%<\/span><\/td>\n<\/tr>\n
Somnolence<\/span><\/td>\nYes<\/span><\/td>\n18%<\/span><\/td>\nYes<\/span><\/td>\n11%<\/span><\/td>\n<\/tr>\n
Agitation<\/span><\/td>\nYes<\/span><\/td>\n3%<\/span><\/td>\nYes<\/span><\/td>\n8%<\/span><\/td>\n<\/tr>\n
Decreased appetite<\/span><\/td>\nNo<\/span><\/td>\nn\/a<\/span><\/td>\nYes<\/span><\/td>\n3%<\/span><\/td>\n<\/tr>\n
Decreased libido<\/span><\/td>\nYes<\/span><\/td>\n2%<\/span><\/td>\nYes<\/span><\/td>\n6%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Source: DailyMed (<\/span>Celexa<\/span><\/a>) Dailymed (<\/span>Zoloft<\/span><\/a>)<\/span><\/p>\n

Drug interactions of Celexa vs. Zoloft<\/h2>\n

Due to their chemical similarities, <\/span>Celexa<\/span> and <\/span>Zoloft<\/span> cause similar concerns for <\/span>drug interactions<\/span>. Both drugs are metabolized through the cytochrome P450 enzyme system. <\/span>Celexa<\/span> and <\/span>Zoloft<\/span> may increase the serum concentrations of antipsychotics, such as aripiprazole, through their inhibition of CYP2D6. If the use of these two drugs together is necessary, patients should be monitored for the effects of higher concentrations of the antipsychotics. In some patients, a dose decrease of the antipsychotic may be necessary.<\/span><\/p>\n

Celexa<\/span> and <\/span>Zoloft<\/span> have the potential to cause <\/span>serotonin syndrome<\/span> when mixed with other drugs with serotonergic actions. <\/span>Serotonin syndrome<\/span><\/a> is the result of abnormally high levels of free serotonin and can result in agitation, dizziness, and increased <\/span>heart rate<\/span>. Drugs such as the migraine medication almotriptan, <\/span>tramadol<\/span> for pain, or <\/span>St. John\u2019s Wort<\/span> supplement may cause this interaction.<\/span><\/p>\n

Zoloft<\/span> may cause a specific type of cardiac arrhythmia known as a prolonged QTc interval when taken with certain classes of medication.\u00a0 It is important that your <\/span>healthcare<\/span> professional and pharmacist have a complete list of medications you are taking in order to appropriately screen for potential interactions.<\/span><\/p>\n

The following list is not intended to be a complete list of <\/span>drug interactions<\/span>. Your doctor or pharmacist can provide a complete list.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Drug<\/b><\/td>\nDrug Class<\/b><\/td>\nCelexa<\/b><\/td>\nZoloft<\/b><\/td>\n<\/tr>\n
Almotriptan<\/span>
\nEletriptan<\/span>
\nOxitriptan<\/span><\/td>\n		5HT Agonist\/Triptans (antimigraine agents)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Dexmethylphenidate<\/span>
\nMethylphenidate<\/span><\/td>\n		Amphetamines<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Alosetron<\/span>
\nOndansetron<\/span>
\nRamosetron<\/span><\/td>\n		5HT3 Antagonists<\/span>
\n(anti-nausea agents)<\/span><\/td>\n		Yes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Aripiprazole<\/span><\/td>\nAntipsychotic<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Aspirin<\/span>
\nIbuprofen<\/span>
\nNaproxen<\/span>
\nDiclofenac<\/span><\/td>\n		Nonsteroidal anti-inflammatory drugs (NSAIDs)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Bemiparin<\/span>
\nEnoxaparin<\/span>
\nHeparin<\/span><\/td>\n		Anticoagulants<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Bupropion<\/span><\/td>\nDopamine\/norepinephrine reuptake inhibitor<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Buspirone<\/span><\/td>\nAntianxiety<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Carbamazepine<\/span><\/td>\nAnticonvulsant<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Esomeprazole<\/span>
\nOmeprazole<\/span><\/td>\n		Proton pump inhibitor<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Fluconazole<\/span><\/td>\nAntifungal<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Fluoxetine<\/span>
\nDuloxetine<\/span>
\nParoxetine<\/span>
\nSertraline<\/span><\/td>\n		SSRIs<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Hydroxychloroquine<\/span><\/td>\nAminoquinoline\/<\/span>Antimalarial<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Linezolid<\/span><\/td>\nAntibiotic<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Cyclobenzaprine<\/span>
\nMetaxalone<\/span><\/td>\n		Muscle relaxers<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Pimozide<\/span><\/td>\nAntipsychotic<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Selegiline<\/span>
\nPhenelzine<\/span>
\nRasagiline<\/span><\/td>\n		Monoamine oxidase inhibitors<\/span> (<\/span>MAOIs<\/span>)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
St. John\u2019s Wort<\/span><\/td>\nHerbal supplement<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Hydrochlorothiazide<\/span>
\nChlorthalidone<\/span>
\nMetolazone<\/span><\/td>\n		Thiazide diuretics<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Tramadol<\/span><\/td>\nOpiate pain reliever<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Amitriptyline<\/span>
\nClomipramine<\/span>
\nDoxepin<\/span>
\nNortriptyline<\/span><\/td>\n		Tricyclic<\/span> antidepressants<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Venlafaxine<\/span><\/td>\nSelective norepinephrine reuptake inhibitor (<\/span>SNRI<\/span>)<\/span><\/td>\nYes\u00a0<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Warnings of Celexa and Zoloft<\/h2>\n

You should not take <\/span>Celexa<\/span> or <\/span>Zoloft<\/span> if you have ever had <\/span>allergic reactions<\/span> to any other <\/span>SSRIs<\/span>.<\/span><\/p>\n

Celexa<\/span> and <\/span>Zoloft<\/span> will not start resolving depressive symptoms immediately. Typically, changes in symptoms take a minimum of two weeks to observe, with most patients needing at least four to six weeks to see if the drug is having an impact on their symptoms.<\/span><\/p>\n

Adults and children who suffer from MDD are more likely to suffer from suicidal ideation. This can get worse if MDD is not adequately treated, or not treated at all. Some studies have shown that <\/span>antidepressant<\/span> drugs, including <\/span>SSRIs<\/span>, can increase <\/span>suicidal thoughts<\/span> in children and young adults. All patients taking <\/span>SSRIs<\/span> should be monitored closely, and <\/span>SSRIs<\/span> should only be used in children and young adults when the benefit clearly outweighs the risk.<\/span><\/p>\n

You should never stop <\/span>Celexa<\/span> or <\/span>Zoloft<\/span> abruptly. You may experience withdrawal symptoms and <\/span>adverse effects<\/span> such as nausea, vomiting, dizziness, and headache. Your <\/span>healthcare<\/span> provider should be consulted before stopping these medications, and they should provide you with a safe manner to taper off of the drug.<\/span><\/p>\n

Celexa<\/span> and <\/span>Zoloft<\/span> have been known to cause QT prolongation, a <\/span>potentially very serious <\/span>side effect<\/span> and can lead to death<\/span>. This is an abnormality in the electrocardiogram characterized by <\/span>Torsade de Pointes (TdP) and ventricular tachycardia. The risk of heart problems goes up with dose. It is important you adhere to the dosage limits set by your prescriber.<\/span><\/p>\n

Serotonin syndrome<\/span><\/a> has been reported with all <\/span>SSRIs<\/span>. This is a condition related to abnormally high levels of serotonin, and can result in the patient feeling agitated, dizzy, and having an increased <\/span>heart rate<\/span>. This can be brought on by the use of two serotonergic drugs together. It is important to refer to the manufacturer\u2019s information on <\/span>drug interactions<\/span> when <\/span>prescribing<\/span> these drugs.<\/span><\/p>\n

Frequently asked questions about Celexa vs. Zoloft<\/h2>\n

What is <\/span>Celexa<\/span>?<\/span><\/h3>\n

Celexa<\/span> is a prescription <\/span>antidepressant medication<\/span>. It belongs to a class of medications known as <\/span>selective serotonin reuptake inhibitors<\/span>. It is prescribed to treat <\/span>major depressive disorder<\/span>, and it works by increasing available serotonin in the neuron synapse. <\/span>Celexa<\/span> is available in 10 mg, 20 mg, and 40 mg strengths.<\/span><\/p>\n

What is <\/span>Zoloft<\/span>?<\/span><\/h3>\n

Zoloft<\/span> is a prescription <\/span>antidepressant medication<\/span> used in the treatment of <\/span>major depressive disorder<\/span> as well as other anxiety and psychiatric disorders. <\/span>Zoloft<\/span> is in a class of drugs known as <\/span>selective serotonin reuptake inhibitors<\/span> (<\/span>SSRIs<\/span>). <\/span>Zoloft<\/span> is available as oral tablets in 25 mg, 50 mg, and 100 mg strengths, as well as an oral liquid concentrate.<\/span><\/p>\n

Are <\/span>Celexa<\/span> and <\/span>Zoloft<\/span> the same?<\/span><\/h3>\n

Celexa<\/span> and <\/span>Zoloft<\/span> are both <\/span>antidepressants<\/span> in the same class, but they are not the same drug. They have different active ingredients, and while both are approved in the <\/span>treatment of depression<\/span>, each carries some unique indications for use in other <\/span>mental health conditions<\/span> as well.<\/span><\/p>\n

Is <\/span>Celexa<\/span> or <\/span>Zoloft<\/span> better?<\/span><\/h3>\n

Celexa<\/span> and <\/span>Zoloft<\/span> have both been shown to be valuable, efficacious, and tolerable treatments for depression. However, <\/span>Celexa<\/span> shows an earlier onset of symptom relief which may be a significant factor in drug choice.<\/span><\/p>\n

Can I use <\/span>Celexa<\/span> or <\/span>Zoloft<\/span> while pregnant?<\/span><\/h3>\n

Celexa<\/span> and <\/span>Zoloft<\/span> are pregnancy category C, meaning there have not been adequate human studies to determine efficacy. The use of <\/span>SSRIs<\/span> must be weighed against the potential harm to the fetus while also considering the well-being of the mother.<\/span><\/p>\n

Can I use <\/span>Celexa<\/span> or <\/span>Zoloft<\/span> with alcohol?<\/span><\/h3>\n

Patients on <\/span>SSRIs<\/span> are cautioned to avoid alcohol as it can increase the toxic effects of <\/span>SSRIs<\/span> and cause significant psychomotor impairment. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Drug overview & main differences | Conditions treated | Efficacy | Insurance coverage and cost comparison | Side effects | Drug interactions | Warnings | FAQ Celexa and Zoloft are two prescription medications used in the treatment of major depression disorder (MDD), sometimes simply referred to as depression. Depression is one of the most prevalent […]<\/p>\n","protected":false},"author":15,"featured_media":11607,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[9777,451,450],"coauthors":[10437],"class_list":["post-3342","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-anxiety","tag-depression","tag-mental-health","wpautop"],"acf":[],"yoast_head":"\nCelexa vs. Zoloft: Differences, similarities, and which is better for you<\/title>\n<meta name=\"description\" content=\"Celexa and Zoloft treat depression but work in different ways. 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