{"id":3548,"date":"2018-12-28T20:11:11","date_gmt":"2018-12-29T01:11:11","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=3548"},"modified":"2025-10-03T10:57:52","modified_gmt":"2025-10-03T14:57:52","slug":"praluent-vs-repatha","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/","title":{"rendered":"Praluent vs. Repatha: Similarities, differences, and which is better for you"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/praluent\"><span style=\"font-weight: 400;\">Praluent<\/span><\/a><span style=\"font-weight: 400;\"> (alirocumab) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/repatha\"><span style=\"font-weight: 400;\">Repatha<\/span><\/a><span style=\"font-weight: 400;\"> (evolocumab) are injectable drugs used to treat high cholesterol, typically when statins or other medications haven\u2019t worked well enough. They belong to a drug class called <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/pcsk9-inhibitors\/\"><span style=\"font-weight: 400;\">PCSK9 inhibitors<\/span><\/a><span style=\"font-weight: 400;\">, which work in the liver to prevent the breakdown of LDL receptors. As a result, it helps the body remove more LDL cholesterol linked to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/heart-disease-statistics\/\"><span style=\"font-weight: 400;\">heart disease<\/span><\/a><span style=\"font-weight: 400;\">, heart attacks, and strokes. While they\u2019re part of the same class of drugs, they have several differences.<\/span><\/p>\n<h2 id=\"what-are-the-main-differences-between-praluent-and-repatha\"><span style=\"font-weight: 400;\">What are the main differences between <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Praluent and Repatha differ in their active ingredients, dosage forms, and age restrictions.<\/span><\/p>\n<h3 id=\"different-ingredients\"><span style=\"font-weight: 400;\">D<\/span><span style=\"font-weight: 400;\">ifferent ingredients<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Though they work the same to increase the liver\u2019s ability to remove LDL from the blood, Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> contain different active ingredients: <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> contains <\/span><span style=\"font-weight: 400;\">alirocumab,<\/span><span style=\"font-weight: 400;\"> while <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> contains <\/span><span style=\"font-weight: 400;\">evolocumab<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"different-strengths-and-formulations\"><span style=\"font-weight: 400;\">Different s<\/span><span style=\"font-weight: 400;\">trengths and formulations<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Both <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are given as <\/span><span style=\"font-weight: 400;\">subcutaneous<\/span><span style=\"font-weight: 400;\"> injections (delivered just under the skin). However, <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> come in different strengths and forms.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/praluent\/what-is\"><span style=\"font-weight: 400;\">Praluent<\/span><\/a><span style=\"font-weight: 400;\"> comes as a 75 mg\/mL or 150 mg\/mL prefilled pen that delivers a single dose at a time. The usual <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> dosage is 75 mg once every two weeks or 300 mg every month for adults with heart disease or primary hyperlipidemia. The dosage can go up to <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2024\/125559s039lbl.pdf\"><span style=\"font-weight: 400;\">150 mg every two weeks<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/repatha\/what-is\"><span style=\"font-weight: 400;\">Repatha<\/span><\/a><span style=\"font-weight: 400;\"> comes in one strength as a 140 mg\/mL <\/span><span style=\"font-weight: 400;\">prefilled syringe<\/span><span style=\"font-weight: 400;\"> or SureClick <\/span><span style=\"font-weight: 400;\">autoinjector<\/span><span style=\"font-weight: 400;\">. The recommended dosage of <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> is 140 mg every two weeks or 420 mg every month. In some cases, the dosage could go up to <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2025\/125522s045lbl.pdf\"><span style=\"font-weight: 400;\">420 mg every two weeks<\/span><\/a><span style=\"font-weight: 400;\">. Repatha was also once available as a Pushtronex system (420 mg\/3.5 mL on-body infusor), but this device was discontinued in 2024.<\/span><\/p>\n<h3 id=\"age-limits\"><span style=\"font-weight: 400;\">Age limits<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Praluent is FDA-approved for use starting at age 8, while Repatha is approved for use starting at age 10. Both are also approved for adults and are used along with a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-cholesterol-diet\/\"><span style=\"font-weight: 400;\">balanced diet<\/span><\/a><span style=\"font-weight: 400;\"> and other cholesterol-lowering medications when needed.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"praluent-vs-repatha-key-differences-comparison\"><span class=\"title\">Praluent vs. Repatha key differences comparison<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Praluent<\/b><\/td>\n<td><b>Repatha<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">PCSK9 inhibitor<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">PCSK9 inhibitor<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">No generic version available<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No generic version available<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Alirocumab<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Evolocumab<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Prefilled pen<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Prefilled syringe<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prefilled <\/span><span style=\"font-weight: 400;\">autoinjector<\/span><span style=\"font-weight: 400;\"> (SureClick)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults with <\/span><span style=\"font-weight: 400;\">heart disease<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">primary hyperlipidemia<\/span><span style=\"font-weight: 400;\">:\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">75 mg every 2 weeks or 300 mg every month<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Certain adults with <\/span><span style=\"font-weight: 400;\">heterozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HeFH<\/span><span style=\"font-weight: 400;\">) or those with <\/span><span style=\"font-weight: 400;\">homozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HoFH<\/span><span style=\"font-weight: 400;\">):\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">150 mg every 2 weeks<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The dosage in children depends on weight<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults with <\/span><span style=\"font-weight: 400;\">heart disease<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">primary hyperlipidemia<\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">140 mg every 2 weeks or 420 mg every month<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Adults and children with <\/span><span style=\"font-weight: 400;\">heterozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HeFH<\/span><span style=\"font-weight: 400;\">):\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">140 mg every 2 weeks or 420 mg every month<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Adults and children with <\/span><span style=\"font-weight: 400;\">homozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HoFH<\/span><span style=\"font-weight: 400;\">):\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">420 mg every month or once every 2 weeks<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Long-term<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children aged 8 years and older<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children aged 10 years and older<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h2 id=\"conditions-treated-by-praluent-and-repatha\"><span style=\"font-weight: 400;\">Conditions treated by <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are prescription injectable drugs used to manage high <\/span><span style=\"font-weight: 400;\">LDL-cholesterol levels<\/span><span style=\"font-weight: 400;\">. These drugs are both approved to treat high <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-long-does-it-take-to-lower-cholesterol\/\"><span style=\"font-weight: 400;\">LDL-cholesterol levels<\/span><\/a><span style=\"font-weight: 400;\"> in people with <\/span><span style=\"font-weight: 400;\">cardiovascular disease<\/span><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK559182\/\"><span style=\"font-weight: 400;\">primary hyperlipidemia<\/span><\/a><span style=\"font-weight: 400;\">, a genetic condition where cholesterol and other blood fats like triglycerides are too high.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Primary hyperlipidemia<\/span><span style=\"font-weight: 400;\"> includes two different types of familial hyperlipidemia: <\/span><span style=\"font-weight: 400;\">heterozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HeFH<\/span><span style=\"font-weight: 400;\">) and <\/span><span style=\"font-weight: 400;\">homozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HoFH<\/span><span style=\"font-weight: 400;\">). These conditions cause extremely high LDL levels that often need stronger treatment than lifestyle changes or <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/statins\"><span style=\"font-weight: 400;\">statins<\/span><\/a><span style=\"font-weight: 400;\"> alone.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People with <\/span><span style=\"font-weight: 400;\">high cholesterol levels<\/span><span style=\"font-weight: 400;\"> are at <\/span><span style=\"font-weight: 400;\">high risk<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">cardiovascular events<\/span><span style=\"font-weight: 400;\">, including heart attacks (<\/span><span style=\"font-weight: 400;\">myocardial infarctions<\/span><span style=\"font-weight: 400;\">), strokes, and severe chest pain (<\/span><span style=\"font-weight: 400;\">unstable angina<\/span><span style=\"font-weight: 400;\">). <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are used alongside an exercise and diet plan, as well as other medications, to reduce the risk of these complications.\u00a0\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-praluent-vs-repatha-conditions-treated\"><span class=\"title\">Compare Praluent vs. Repatha conditions treated<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Condition<\/b><\/td>\n<td><b>Praluent<\/b><\/td>\n<td><b>Repatha<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">High <\/span><span style=\"font-weight: 400;\">LDL-cholesterol levels<\/span><span style=\"font-weight: 400;\"> in people with heart<\/span><span style=\"font-weight: 400;\"> disease<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">High <\/span><span style=\"font-weight: 400;\">LDL-cholesterol levels<\/span><span style=\"font-weight: 400;\"> in people with <\/span><span style=\"font-weight: 400;\">primary hyperlipidemia<\/span><span style=\"font-weight: 400;\">, such as <\/span><span style=\"font-weight: 400;\">heterozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HeFH<\/span><span style=\"font-weight: 400;\">) or <\/span><span style=\"font-weight: 400;\">homozygous familial hypercholesterolemia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">HoFH<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<h2 id=\"is-praluent-or-repatha-more-effective\"><span style=\"font-weight: 400;\">Is <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> more effective?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are both effective medications that can help <\/span><span style=\"font-weight: 400;\">lower cholesterol<\/span><span style=\"font-weight: 400;\">. There aren\u2019t any large studies that directly compare the two drugs side by side, but <\/span><span style=\"font-weight: 400;\">clinical trials<\/span><span style=\"font-weight: 400;\"> show they\u2019re both effective when compared to a <\/span><span style=\"font-weight: 400;\">placebo<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10626223\/\"><span style=\"font-weight: 400;\">2023 meta-analysis<\/span><\/a><span style=\"font-weight: 400;\"> of more than 76,000 patients found that both medications lower LDL cholesterol and help prevent heart attacks, strokes, and the need for procedures like stent placement. Both drugs were also safe without any serious side effects. However, Praluent may lower the risk of death slightly more than Repatha.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most recent American College of Cardiology and American Heart Association <\/span><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIR.0000000000001309\"><span style=\"font-weight: 400;\">guidelines<\/span><\/a><span style=\"font-weight: 400;\"> recommend more aggressive cholesterol-lowering for people who\u2019ve had a recent heart attack or other acute coronary event. If LDL goals aren\u2019t met with statins alone, or if someone can\u2019t take statins, adding a PCSK9 inhibitor like Praluent or Repatha is recommended.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Before using <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">, it\u2019s important to get <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> and discuss all <\/span><span style=\"font-weight: 400;\">treatment options<\/span><span style=\"font-weight: 400;\"> with a <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider.\u00a0<\/span><\/p>\n<h2 id=\"coverage-and-cost-comparison-of-praluent-vs-repatha\"><span style=\"font-weight: 400;\">Coverage and cost comparison of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> vs. <\/span><span style=\"font-weight: 400;\">Repatha<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many Medicare and commercial insurance plans may help cover the cost of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\">. However, there is no generic version of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> available, and the average retail price is around $710. A SingleCare discount card may help lower the <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/praluent\"><span style=\"font-weight: 400;\">price of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Medicare and commercial insurance plans also provide coverage for <\/span><span style=\"font-weight: 400;\">Repatha, although it depends on the plan<\/span><span style=\"font-weight: 400;\">. Without insurance, the average price for Repatha is around $795. A SingleCare discount card is a potential <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/repatha\"><span style=\"font-weight: 400;\">savings option for Repatha<\/span><\/a><span style=\"font-weight: 400;\"> for someone without insurance or adequate insurance coverage.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-cost-and-coverage-of-praluent-vs-repatha\"><span class=\"title\">Compare cost and coverage of Praluent vs. Repatha<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Praluent<\/b><\/td>\n<td><b>Repatha<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">1 supply of 2, 75 mg\/mL pens<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 supply of 2, 140 mg\/mL syringes\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost*<\/b><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/praluent\"><span style=\"font-weight: 400;\">$512<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/repatha\"><span style=\"font-weight: 400;\">$498<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><i><span style=\"font-weight: 400;\">*Cost at time of publication. Prices fluctuate and vary by pharmacy and location.<\/span><\/i><\/h5>\n<h2 id=\"common-side-effects-of-praluent-vs-repatha\"><span style=\"font-weight: 400;\">Common side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> vs. <\/span><span style=\"font-weight: 400;\">Repatha<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> cause similar side effects. The most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are reactions at the <\/span><span style=\"font-weight: 400;\">injection site<\/span><span style=\"font-weight: 400;\">. Reactions might include mild redness, swelling, or soreness around the area where the injection is given.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> can also cause cold and flu-like symptoms. After using <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">, a person may experience side effects like nasal congestion, cough, muscle pain, and diarrhea.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> may also cause side effects like high blood sugar levels, back pain, headache, and dizziness.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h3 id=\"compare-side-effects-of-praluent-vs-repatha\"><span class=\"title\">Compare side effects of Praluent vs. Repatha<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td colspan=\"2\"><b>Praluent<\/b><\/td>\n<td colspan=\"2\"><b>Repatha<\/b><\/td>\n<\/tr>\n<tr class=\"header-row\">\n<td><b>Side effect<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Frequency<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Frequency<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Injection site<\/span><span style=\"font-weight: 400;\"> reactions<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">7%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">6%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Cold and flu symptoms<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Diarrhea<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">High blood sugar levels<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">&#8211;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Back pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">&#8211;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">6%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Muscle pain<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Headache\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">&#8211;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Dizziness<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No<\/span><\/td>\n<td><span style=\"font-weight: 400;\">&#8211;<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<td><span style=\"font-weight: 400;\">4%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h5><i><span style=\"font-weight: 400;\">Frequency is not based on data from a head-to-head trial. This may not be a complete list of adverse effects that can occur. Please refer to your <\/span><\/i><i><span style=\"font-weight: 400;\">healthcare<\/span><\/i><i><span style=\"font-weight: 400;\"> provider to learn more.<\/span><\/i><\/h5>\n<h5><span style=\"font-weight: 400;\">Source: DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=7bcfbac2-e8ac-4569-8edc-bcde3b1fd172\"><span style=\"font-weight: 400;\">Praluent<\/span><\/a><span style=\"font-weight: 400;\">), DailyMed (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=cd61e902-166d-4aa6-9f3c-a18c1008d07e\"><span style=\"font-weight: 400;\">Repatha<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/h5>\n<h2 id=\"drug-interactions-of-praluent-vs-repatha\"><span style=\"font-weight: 400;\">Drug interactions of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> vs. <\/span><span style=\"font-weight: 400;\">Repatha<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Combining <\/span><span style=\"font-weight: 400;\">statin<\/span><span style=\"font-weight: 400;\"> medications with <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> may cause <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8635697\/\"><span style=\"font-weight: 400;\">reduced blood levels<\/span><\/a><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">. However, despite possible reduced levels, <\/span><span style=\"font-weight: 400;\">clinical trials<\/span><span style=\"font-weight: 400;\"> have not found any evidence that <\/span><span style=\"font-weight: 400;\">statin therapy<\/span><span style=\"font-weight: 400;\"> has an impact on how <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> works. <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> is often used in combination with a <\/span><span style=\"font-weight: 400;\">statin<\/span><span style=\"font-weight: 400;\"> medication. There are no known drug interactions between <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> and other drugs.\u00a0<\/span><\/p>\n<h2 id=\"warnings-of-praluent-and-repatha\"><span style=\"font-weight: 400;\">Warnings of <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Both <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> carry warnings for possible <\/span><a href=\"https:\/\/www.researchgate.net\/publication\/326592338_Are_Injection_Site_Reactions_in_Monoclonal_Antibody_Therapies_Caused_by_Polysorbate_Excipient_Degradants\"><span style=\"font-weight: 400;\">allergic reactions<\/span><\/a><span style=\"font-weight: 400;\"> after injection. Signs and symptoms of an <\/span><span style=\"font-weight: 400;\">allergic reaction<\/span><span style=\"font-weight: 400;\"> can include rash, hives, redness, and itching. Contact a <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider if signs or symptoms of an <\/span><span style=\"font-weight: 400;\">allergic reaction<\/span><span style=\"font-weight: 400;\"> develop after using <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> syringes and <\/span><span style=\"font-weight: 400;\">autoinjectors<\/span><span style=\"font-weight: 400;\"> may contain dry natural rubber. People who are allergic to latex or rubber may need to use <\/span><span style=\"font-weight: 400;\">the<\/span><span style=\"font-weight: 400;\"> syringes and <\/span><span style=\"font-weight: 400;\">autoinjectors that don\u2019t contain natural rubber latex<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There isn\u2019t enough research to determine whether <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> is safe in women who are pregnant or <\/span><span style=\"font-weight: 400;\">breastfeeding<\/span><span style=\"font-weight: 400;\">. Although some <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40790812\/\"><span style=\"font-weight: 400;\">case reports<\/span><\/a><span style=\"font-weight: 400;\"> suggest PCSK9 inhibitors may be safe, there may still be potential risks to an unborn baby or <\/span><span style=\"font-weight: 400;\">breastfeeding<\/span><span style=\"font-weight: 400;\"> infant. Discuss <\/span><span style=\"font-weight: 400;\">treatment options<\/span><span style=\"font-weight: 400;\"> with a <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider while pregnant or <\/span><span style=\"font-weight: 400;\">breastfeeding<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2 id=\"frequently-asked-questions-about-praluent-vs-repatha\"><span style=\"font-weight: 400;\">Frequently asked questions about <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> vs. <\/span><span style=\"font-weight: 400;\">Repatha<\/span><\/h2>\n<h3 id=\"are-praluent-and-repatha-the-same\"><span style=\"font-weight: 400;\">Are <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> the same?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are both <\/span><span style=\"font-weight: 400;\">PCSK9 inhibitors<\/span><span style=\"font-weight: 400;\">, but they contain different ingredients. <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> contains <\/span><span style=\"font-weight: 400;\">alirocumab,<\/span><span style=\"font-weight: 400;\"> while <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> contains <\/span><span style=\"font-weight: 400;\">evolocumab<\/span><span style=\"font-weight: 400;\">. They also have different manufacturers: <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> is manufactured by <\/span><span style=\"font-weight: 400;\">Regeneron,<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> is manufactured by <\/span><span style=\"font-weight: 400;\">Amgen<\/span><span style=\"font-weight: 400;\">. They also have different dosages and potential side effects.\u00a0<\/span><\/p>\n<h3 id=\"is-praluent-or-repatha-better\"><span style=\"font-weight: 400;\">Is <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> better?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Both <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> are effective for lowering <\/span><span style=\"font-weight: 400;\">LDL cholesterol<\/span><span style=\"font-weight: 400;\"> and reducing the <\/span><span style=\"font-weight: 400;\">risk of heart attack<\/span><span style=\"font-weight: 400;\">, stroke, or chest pain. They are similarly effective when used along with <\/span><span style=\"font-weight: 400;\">statin<\/span><span style=\"font-weight: 400;\"> medications or other <\/span><span style=\"font-weight: 400;\">cholesterol<\/span><span style=\"font-weight: 400;\">-lowering drugs.\u00a0<\/span><\/p>\n<h3 id=\"can-i-use-praluent-or-repatha-while-pregnant\"><span style=\"font-weight: 400;\">Can I use <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> while pregnant?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">It is not known whether <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> is safe to use while pregnant. <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> were not found to cause significant adverse effects in <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK582695\/\"><span style=\"font-weight: 400;\">animal studies<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">However, <\/span><span style=\"font-weight: 400;\">caution should be taken before using <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> while pregnant. Discuss the potential benefits and risks with a <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider.\u00a0<\/span><\/p>\n<h3 id=\"can-i-use-praluent-or-repatha-with-alcohol\"><span style=\"font-weight: 400;\">Can I use <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\"> with alcohol?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Alcohol is not known to interact with <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">. It is likely safe to drink alcohol in moderation while using <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Repatha<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"is-praluent-effective-without-a-statin\"><span style=\"font-weight: 400;\">Is <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> effective without a <\/span><span style=\"font-weight: 400;\">statin<\/span><span style=\"font-weight: 400;\">?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Praluent is most often prescribed alongside a statin to help lower cholesterol. However, it can also be effective when used on its own, especially for people who can\u2019t take statins. For people with very high cholesterol levels, Praluent may offer better results when used with a statin.\u00a0<\/span><\/p>\n<h3 id=\"does-praluent-cause-weight-gain\"><span style=\"font-weight: 400;\">Does <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> cause weight gain?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Weight gain is not a listed side effect based on data from the <\/span><span style=\"font-weight: 400;\">Praluent<\/span> <span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\"> label. Some people may see weight gain while taking <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> due to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/medications-that-cause-weight-gain\/\"><span style=\"font-weight: 400;\">other medications<\/span><\/a><span style=\"font-weight: 400;\"> or health conditions. Talk to a <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider if weight gain becomes a problem while using <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"how-long-can-you-take-praluent\"><span style=\"font-weight: 400;\">How long can you take <\/span><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\">?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Praluent<\/span><span style=\"font-weight: 400;\"> is a long-term <\/span><span style=\"font-weight: 400;\">treatment option<\/span><span style=\"font-weight: 400;\"> for high <\/span><span style=\"font-weight: 400;\">LDL-cholesterol levels<\/span><span style=\"font-weight: 400;\">. It is injected under the skin every two or four weeks. <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Praluent (alirocumab) and Repatha (evolocumab) are injectable drugs used to treat high cholesterol, typically when statins or other medications haven\u2019t worked well enough. They belong to a drug class called PCSK9 inhibitors, which work in the liver to prevent the breakdown of LDL receptors. As a result, it helps the body remove more LDL cholesterol [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":11644,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[790,737,20952,4350],"coauthors":[8669],"class_list":["post-3548","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-chronic-disease","tag-heart-health","tag-high-cholesterol","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Praluent vs. Repatha: Which is better for you?<\/title>\n<meta name=\"description\" content=\"Praluent and Repatha treat high cholesterol but work in different ways. Compare the side effects and cost of these drugs to find out which is best for you.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Praluent vs. Repatha: Similarities, differences, and which is better for you\" \/>\n<meta property=\"og:description\" content=\"Praluent and Repatha treat high cholesterol but work in different ways. Compare the side effects and cost of these drugs to find out which is best for you.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2018-12-29T01:11:11+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-10-03T14:57:52+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2018\/12\/Praluent-vs-Repatha.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Gerardo Sison, Pharm.D.\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Gerardo Sison, Pharm.D.\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/\"},\"author\":{\"name\":\"SingleCare Team\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\"},\"headline\":\"Praluent vs. Repatha: Similarities, differences, and which is better for you\",\"datePublished\":\"2018-12-29T01:11:11+00:00\",\"dateModified\":\"2025-10-03T14:57:52+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/\"},\"wordCount\":1687,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2018\\\/12\\\/Praluent-vs-Repatha.png\",\"keywords\":[\"Chronic disease\",\"Heart health\",\"High cholesterol\",\"Prescription savings\"],\"articleSection\":[\"Drug vs. Drug\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/\",\"name\":\"Praluent vs. Repatha: Which is better for you?\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2018\\\/12\\\/Praluent-vs-Repatha.png\",\"datePublished\":\"2018-12-29T01:11:11+00:00\",\"dateModified\":\"2025-10-03T14:57:52+00:00\",\"description\":\"Praluent and Repatha treat high cholesterol but work in different ways. Compare the side effects and cost of these drugs to find out which is best for you.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2018\\\/12\\\/Praluent-vs-Repatha.png\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2018\\\/12\\\/Praluent-vs-Repatha.png\",\"width\":1024,\"height\":576,\"caption\":\"Two syringes representing Praluent vs Repatha comparison\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/praluent-vs-repatha\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Praluent vs. Repatha: Similarities, differences, and which is better for you\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"name\":\"The Checkup, a health blog by SingleCare\",\"description\":\"Read the latest in prescription, wellness, and healthcare news\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\",\"name\":\"SingleCare\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"width\":1200,\"height\":630,\"caption\":\"SingleCare\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/singlecare\",\"https:\\\/\\\/x.com\\\/SingleCare\",\"https:\\\/\\\/www.instagram.com\\\/singlecare\\\/?hl=en\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/singlecare\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCd9kiPIjCQw95-2BHCYePKA\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\",\"name\":\"SingleCare Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=gcda8e0f4c5718cb7f68c0ee812f6fafb\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g\",\"caption\":\"SingleCare Team\"},\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/author\\\/singlecareteam\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Praluent vs. Repatha: Which is better for you?","description":"Praluent and Repatha treat high cholesterol but work in different ways. Compare the side effects and cost of these drugs to find out which is best for you.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/","og_locale":"en_US","og_type":"article","og_title":"Praluent vs. Repatha: Similarities, differences, and which is better for you","og_description":"Praluent and Repatha treat high cholesterol but work in different ways. Compare the side effects and cost of these drugs to find out which is best for you.","og_url":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/","og_site_name":"The Checkup","article_publisher":"https:\/\/www.facebook.com\/singlecare","article_published_time":"2018-12-29T01:11:11+00:00","article_modified_time":"2025-10-03T14:57:52+00:00","og_image":[{"width":1024,"height":576,"url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2018\/12\/Praluent-vs-Repatha.png","type":"image\/png"}],"author":"Gerardo Sison, Pharm.D.","twitter_card":"summary_large_image","twitter_creator":"@SingleCare","twitter_site":"@SingleCare","twitter_misc":{"Written by":"Gerardo Sison, Pharm.D.","Est. reading time":"8 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#article","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/"},"author":{"name":"SingleCare Team","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/403ef50a9f402fb9ce49c429659555f5"},"headline":"Praluent vs. Repatha: Similarities, differences, and which is better for you","datePublished":"2018-12-29T01:11:11+00:00","dateModified":"2025-10-03T14:57:52+00:00","mainEntityOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/"},"wordCount":1687,"commentCount":0,"publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2018\/12\/Praluent-vs-Repatha.png","keywords":["Chronic disease","Heart health","High cholesterol","Prescription savings"],"articleSection":["Drug vs. Drug"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/","url":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/","name":"Praluent vs. Repatha: Which is better for you?","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#primaryimage"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2018\/12\/Praluent-vs-Repatha.png","datePublished":"2018-12-29T01:11:11+00:00","dateModified":"2025-10-03T14:57:52+00:00","description":"Praluent and Repatha treat high cholesterol but work in different ways. Compare the side effects and cost of these drugs to find out which is best for you.","breadcrumb":{"@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#primaryimage","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2018\/12\/Praluent-vs-Repatha.png","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2018\/12\/Praluent-vs-Repatha.png","width":1024,"height":576,"caption":"Two syringes representing Praluent vs Repatha comparison"},{"@type":"BreadcrumbList","@id":"https:\/\/www.singlecare.com\/blog\/praluent-vs-repatha\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.singlecare.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Praluent vs. Repatha: Similarities, differences, and which is better for you"}]},{"@type":"WebSite","@id":"https:\/\/www.singlecare.com\/blog\/#website","url":"https:\/\/www.singlecare.com\/blog\/","name":"The Checkup, a health blog by SingleCare","description":"Read the latest in prescription, wellness, and healthcare news","publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.singlecare.com\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.singlecare.com\/blog\/#organization","name":"SingleCare","url":"https:\/\/www.singlecare.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","width":1200,"height":630,"caption":"SingleCare"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/singlecare","https:\/\/x.com\/SingleCare","https:\/\/www.instagram.com\/singlecare\/?hl=en","https:\/\/www.linkedin.com\/company\/singlecare\/","https:\/\/www.youtube.com\/channel\/UCd9kiPIjCQw95-2BHCYePKA"]},{"@type":"Person","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/403ef50a9f402fb9ce49c429659555f5","name":"SingleCare Team","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=gcda8e0f4c5718cb7f68c0ee812f6fafb","url":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g","caption":"SingleCare Team"},"url":"https:\/\/www.singlecare.com\/blog\/author\/singlecareteam\/"}]}},"_links":{"self":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/3548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/comments?post=3548"}],"version-history":[{"count":0,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/3548\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media\/11644"}],"wp:attachment":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media?parent=3548"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/categories?post=3548"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/tags?post=3548"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/coauthors?post=3548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}