{"id":37393,"date":"2021-07-22T09:30:44","date_gmt":"2021-07-22T13:30:44","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=37393"},"modified":"2026-07-10T18:47:04","modified_gmt":"2026-07-10T22:47:04","slug":"medications-that-cause-heat-intolerance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/medications-that-cause-heat-intolerance\/","title":{"rendered":"14 medications that make you sensitive to the heat"},"content":{"rendered":"<p>Summer is in full swing\u2014and there\u2019s <i>another <\/i>heat wave slamming your area. You\u2019re ready to hit the beach to cool off from the extreme heat. As long as you remember to reapply sunscreen and stay hydrated, you\u2019re enjoying the hot temperatures safely&#8230;right? Not so fast! If you take any daily pills\u2014prescription or over-the-counter\u2014check with your pharmacist first. Certain medications that cause sun sensitivity and heat illness can ruin a day of fun in the sun, and have dangerous side effects as temperatures skyrocket.\u00a0<\/p>\n<h2 id=\"what-is-heat-intolerance\">What is heat intolerance?<\/h2>\n<p>Also known as hypersensitivity to the heat, heat intolerance is more than just feeling uncomfortable when temperatures rise. It\u2019s a condition that occurs when your body can\u2019t regulate its temperature properly.\u00a0<\/p>\n<p>As it gets hotter outside, the hypothalamus in your brain sends messages through your nerves that tell your skin to cool off by sweating. When the moisture evaporates off your skin, it decreases your core temperature. If something disrupts this process, your body is unable to cool down\u2014and that can lead to unpleasant symptoms like nausea, dizziness, or even a heat-related illness.<\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/heat-illness\/\"><b>6 heat-related illnesses you should watch out for this summer<\/b><\/a><\/p>\n<p>Heat intolerance has many causes: <a href=\"https:\/\/www.singlecare.com\/blog\/hot-weather-health-risks\/\">certain health conditions<\/a>, age, weight, and the medications that you take.\u00a0<\/p>\n<h2 id=\"14-medications-that-cause-heat-intolerance\">14 medications that cause heat intolerance<\/h2>\n<p>There are several types of common medications that can increase your sensitivity to the heat:<\/p>\n<ol>\n<li>Blood pressure medication<\/li>\n<li>Antihistamines<\/li>\n<li>Decongestants<\/li>\n<li>Anticholinergics<\/li>\n<li>Stimulants<\/li>\n<li>Psychiatric medications<\/li>\n<li>Steroids<\/li>\n<li>Thyroid medications<\/li>\n<li>Chemotherapy drugs<\/li>\n<li>Muscle relaxants<\/li>\n<li>Hormonal medications<\/li>\n<li>Cholesterol-lowering medications<\/li>\n<li>Antibiotics<\/li>\n<li>Retinoids<\/li>\n<\/ol>\n<p>Additionally, there are many combination drugs, so even if your medication doesn\u2019t make this list, it\u2019s always a good idea to check with a provider before heading out on a hot day.<\/p>\n<h3 id=\"1-blood-pressure-medications\">1. Blood pressure medications<\/h3>\n<p>Certain prescription treatments for high blood pressure, also known as hypertension, can put you at higher risk of heat intolerance. This is especially true for two types of medications: thiazide diuretics and beta blockers.<\/p>\n<h4 id=\"thiazide-diuretics\">Thiazide diuretics\u00a0<\/h4>\n<p>\u201cCertain medications, called diuretics, force fluid out of our bodies through our kidneys to control high blood pressure and heart failure,\u201d says <a href=\"https:\/\/www.providence.org\/doctors\/profile\/199050-david-michael-cutler\">David Cutler, MD<\/a>, family medicine physician at Santa Monica Family Physicians in California. \u201cThese medications could cause dehydration, a potentially grave danger in hot weather.\u201d Thiazide diuretics, such as <a href=\"https:\/\/www.singlecare.com\/prescription\/chlorthalidone\">chlorthalidone<\/a> and <a href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide\">Microzide (hydrochlorothiazide)<\/a>, are known to have this effect. Additionally, recent <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6436572\/\">studies<\/a> have found that hydrochlorothiazide, as well as combination drugs, may increase the risk of certain types of skin cancer.<\/p>\n<h4 id=\"beta-blockers\">Beta blockers<\/h4>\n<p>Beta blockers, such as <a href=\"https:\/\/www.singlecare.com\/prescription\/metoprolol-succinate-er\">Toprol XL (metoprolol)<\/a> and <a href=\"https:\/\/www.singlecare.com\/prescription\/propranolol-hcl\">Inderal (propranolol)<\/a>, can decrease blood flow to the skin, which can inhibit sweating. \u201cIt mainly has to do with how the blood flows to the skin,\u201d says <a href=\"https:\/\/www.doximity.com\/pub\/dawn-shill-pharmacist\">Dawn Shill<\/a>, Pharm.D., a pharmacist for the Veterans Affairs Healthcare System in Anchorage, Alaska. \u201cThe blood vessels don\u2019t dilate as they should to allow heat to escape with certain blood pressure medications. By constricting blood flow, the body can\u2019t regulate temperature as much.\u201d<\/p>\n<p>Both effects make it harder for your body to cool off.<\/p>\n<h4 id=\"other-blood-pressure-medications\">Other blood pressure medications<\/h4>\n<p>In addition to these medications, other medications used to lower blood pressure can cause severe sunburn and skin irritation. They include:<\/p>\n<ul>\n<li>Calcium channel blockers like <a href=\"https:\/\/www.singlecare.com\/prescription\/amlodipine-besylate\">amlodipine<\/a><\/li>\n<li>Angiotensin II receptor blockers (ARBs) like <a href=\"https:\/\/www.singlecare.com\/prescription\/losartan-potassium\">losartan<\/a><\/li>\n<li>ACE inhibitors like <a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril\">lisinopril<\/a><\/li>\n<\/ul>\n<p>If you\u2019re taking one of these medications and can\u2019t avoid sun exposure, it is recommended that you use sunscreen with an SPF of over 30 and wear protective clothing.<\/p>\n<h3 id=\"2-antihistamines\">2. Antihistamines<\/h3>\n<p>You take a daily dose of an antihistamine such as <a href=\"https:\/\/www.singlecare.com\/prescription\/benadryl-allergy\">Benadryl (diphenhydramine)<\/a> to manage your seasonal allergies. This over-the-counter treatment is very effective at stopping sniffling, sneezing, and itchy eyes. But did you know some of the same medications can prevent you from sweating? Combine that with the summer sun, and it can increase your chances of overheating. This effect is more common with first-generation antihistamines, like Benadryl. Second-generation antihistamines, such as Claritin, Zyrtec, and Allegra, are less likely to have this effect.<\/p>\n<p>\u201cAntihistamines produce an anticholinergic effect commonly referred to as a \u2018drying\u2019 effect,\u201d explains <a href=\"https:\/\/www.singlecare.com\/blog\/author\/kristi-torres\/\">Kristi Torres<\/a>, Pharm.D., a member of the SingleCare Medical Review Board. \u201cThe same mechanism that allows antihistamines to slow mucus production is also responsible for your body producing less sweat. When your body is not able to sweat, it is difficult to regulate your internal temperature in the face of high external temperatures.\u201d If this is a concern, ask your healthcare provider or pharmacist to help you select an appropriate antihistamine.<\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/taking-antihistamines-daily\/\"><b>Can I take antihistamines every day?<\/b><\/a><\/p>\n<h3 id=\"3-decongestants\">3. Decongestants<\/h3>\n<p>Getting sick is likely the last thing you\u2019re thinking about in the summer. But, <a href=\"https:\/\/www.singlecare.com\/blog\/summer-cold\/\">colds can strike year-round<\/a>, even in warm weather. If you\u2019re all stuffed up and reaching for the <a href=\"https:\/\/www.singlecare.com\/prescription\/sudafed-sinus-congestion-24hr\">Sudafed (pseudoephedrine)<\/a>, you may need to postpone your pool day for some good old-fashioned rest and relaxation.\u00a0<\/p>\n<p>\u201cDecongestants work the same way as blood pressure medications, decreasing the blood flow to the skin,\u201d Dr. Shill says. That can be dangerous on an already hot day.<\/p>\n<h3 id=\"4-overactive-bladder-treatments\">4. Overactive bladder treatments<\/h3>\n<p>Anticholinergics block the action of involuntary muscle movements that can make you feel like you need the restroom when you don\u2019t. That\u2019s a positive when you\u2019re dealing with incontinence or poor bladder control. Unfortunately, they have a side effect that can spell trouble in the summer. Medications like <a href=\"https:\/\/www.singlecare.com\/prescription\/oxybutynin-chloride\">Ditropan (oxybutynin)<\/a> or <a href=\"https:\/\/www.singlecare.com\/prescription\/tolterodine-tartrate\">Detrol (tolterodine)<\/a> can reduce sweating, which reduces your ability to cool off.<\/p>\n<h3 id=\"5-stimulant-medications-for-adhd\">5. Stimulant medications for ADHD<\/h3>\n<p>Certain prescriptions that treat attention deficit hyperactivity disorder (ADHD) fall into a class of medications known as stimulants. This includes well-known medications such as <a href=\"https:\/\/www.singlecare.com\/prescription\/adderall-xr\">Adderall (amphetamine\/dextroamphetamine)<\/a> and <a href=\"https:\/\/www.singlecare.com\/prescription\/ritalin\">Ritalin (methylphenidate)<\/a>. These drugs raise your body temperature, increasing the risk of heat intolerance.\u00a0<\/p>\n<p>On top of that, they physically constrict blood vessels and reduce blood flow to the skin. \u201cIn the heat, blood flow needs to be increased to the skin in order to cool the body down,\u201d explains Anthony Puopolo, MD, board-certified physician and chief medical officer of LifeMD. Stimulant medications can prevent that reaction.<\/p>\n<h3 id=\"6-psychiatric-medications\">6. Psychiatric medications<\/h3>\n<p>Medications used to treat certain mental health conditions and Parkinson\u2019s disease all have one thing in common: They affect the hypothalamus. Since this region of the brain is essential to cooling, it can inhibit your ability to reduce body temperature on hot days. These medications can also decrease your thirst reflex, increasing dehydration.<\/p>\n<p>There are many different types of <a href=\"https:\/\/www.state.nj.us\/humanservices\/dmhas\/publications\/miscl\/Sum_%20Ht_SunRisks_bw.pdf\">psychiatric<\/a> prescriptions that can lead to heat intolerance or an exaggerated reaction to the sun:<\/p>\n<ul>\n<li>Antipsychotics such as <a href=\"https:\/\/www.singlecare.com\/prescription\/haloperidol\">Haldol (haloperidol)<\/a> or<a href=\"https:\/\/www.singlecare.com\/prescription\/chlorpromazine-hcl\"> Thorazine (chlorpromazine)<\/a><\/li>\n<li>Dopaminergics such as <a href=\"https:\/\/www.singlecare.com\/prescription\/carbidopa-levodopa\">Sinemet (carbidopa\/levodopa)<\/a>\u00a0<\/li>\n<li>Tricyclic antidepressants such as <a href=\"https:\/\/www.singlecare.com\/prescription\/amitriptyline-hcl\">Elavil (amitriptyline)<\/a> and <a href=\"https:\/\/www.singlecare.com\/prescription\/pamelor\">Pamelor (nortriptyline)<\/a><\/li>\n<li>Certain other antidepressants, such as <a href=\"https:\/\/www.singlecare.com\/prescription\/wellbutrin-xl\">Wellbutrin (bupropion)<\/a>\u00a0<\/li>\n<\/ul>\n<h3 id=\"7-steroids\">7. Steroids<\/h3>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15910167\/\">Corticosteroids<\/a>, like <a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\">prednisone<\/a>, can cause us to sweat more or change how blood circulates in our skin, dysregulating how our bodies control temperature. For people on long-term steroid treatment, this often means feeling extra sensitive to heat and a higher risk of heat-related issues.<\/p>\n<h3 id=\"8-thyroid-medications\">8. Thyroid medications<\/h3>\n<p>If you\u2019re taking <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/8808101\/\">medications for thyroid disorders<\/a>, such as <a href=\"https:\/\/www.singlecare.com\/prescription\/levothyroxine-sodium\">Synthroid (levothyroxine<\/a>) for hypothyroidism, you might notice you\u2019re more intolerant to heat. These medications can boost your metabolism and energy use, which sometimes leads to too much thyroid hormone in the body. The result? You experience excessive sweating and feel warmer than usual, even in places where you\u2019d typically be comfortable.<\/p>\n<h3 id=\"9-chemotherapy-drugs\">9. Chemotherapy drugs<\/h3>\n<p>Some <a href=\"https:\/\/www.sciencedaily.com\/releases\/2023\/08\/230816134651.htm\">chemotherapy drugs<\/a>, like <a href=\"https:\/\/www.singlecare.com\/prescription\/doxorubicin-hcl-liposomal\">Doxil (doxorubicin)<\/a> or cyclophosphamide, can interfere with internal heat regulation. They may affect the hypothalamus, harm the cells that help with thermoregulation, and cause fevers and other reactions that make you more sensitive to heat. Patients going through chemotherapy often struggle with heat, especially during their treatment cycles.<\/p>\n<h3 id=\"10-muscle-relaxants\">10. Muscle relaxants<\/h3>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK507838\/\">Muscle relaxants<\/a> such as <a href=\"https:\/\/www.singlecare.com\/prescription\/cyclobenzaprine-hcl-er\">Amrix (cyclobenzaprine)<\/a> and <a href=\"https:\/\/www.singlecare.com\/prescription\/baclofen\">Fleqsuvy (baclofen)<\/a> can lead to heat intolerance because they affect the central nervous system, which regulates temperature. These drugs might make it harder for your body to sweat or change how you perceive temperature, making you feel uncomfortable in warm conditions.\u00a0<\/p>\n<h3 id=\"11-hormonal-medications\">11. Hormonal medications<\/h3>\n<p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8237993\/\">Hormonal treatments<\/a>, including <a href=\"https:\/\/www.singlecare.com\/resources\/estrogen\">estrogen replacement therapy<\/a> and certain <a href=\"https:\/\/www.singlecare.com\/resources\/birth-control\">contraceptives<\/a>, can influence how your body handles heat. Estrogen can affect blood flow and sweating, increasing heat sensitivity, especially when starting treatment. Women on hormone therapy may experience hot flashes and other symptoms that make them feel uncomfortably warm during physical activity or in hot environments.<\/p>\n<h3 id=\"12-cholesterol-lowering-medications\">12. Cholesterol-lowering medications<\/h3>\n<p>Statins, such as simvastatin, atorvastatin, pravastatin, and lovastatin,\u00a0 are commonly prescribed to treat high cholesterol and lower the risk of heart attack. These medications can cause <a href=\"https:\/\/www.geisinger.org\/health-and-wellness\/wellness-articles\/2024\/08\/08\/13\/40\/sun-drug-interactions\">photosensitivity<\/a>, resulting in an itchy, painful rash after sun exposure and increasing sunburn risk.\u00a0<\/p>\n<p>If you take any of the above, talk to your healthcare provider or pharmacist before planning a picnic in the heat of the day.<\/p>\n<h3 id=\"13-antibiotics\">13. Antibiotics<\/h3>\n<p>While they won\u2019t make you sensitive to high temperatures, certain antibiotics can make you more sensitive to the sun and likely to burn. Examples include tetracyclines, sulfa antibiotics, and quinolones like <a href=\"https:\/\/www.singlecare.com\/prescription\/ciprofloxacin\">ciprofloxacin<\/a> or <a href=\"https:\/\/www.singlecare.com\/prescription\/levofloxacin\">levofloxacin<\/a>. If you are taking an antibiotic, check with your healthcare provider to see if you need to take any precautions regarding sun exposure.<\/p>\n<h3 id=\"14-retinoids\">14. Retinoids<\/h3>\n<p>Retinoids, including both prescription-strength retinoic acid and over-the-counter retinol, can increase your skin\u2019s sensitivity to sunlight. They work by speeding up cell turnover, which can thin the outer layer of skin and reduce its natural protective barrier. As a result, skin becomes more prone to sunburn, irritation, and heat-related reactions. This heightened sensitivity is why it\u2019s often recommended to apply retinoids at night and use broad-spectrum sunscreen daily.<\/p>\n<h2 id=\"what-signs-of-heat-intolerance-should-you-watch-for\">What signs of heat intolerance should you watch for?<\/h2>\n<p>The first sign of heat intolerance is feeling hot and uncomfortable. In addition, you might experience symptoms such as:<\/p>\n<ul>\n<li>Headache<\/li>\n<li>Dizziness<\/li>\n<li>Cramps<\/li>\n<li>Nausea or vomiting<\/li>\n<li>Weakness<\/li>\n<li>Flushed skin<\/li>\n<\/ul>\n<h2 id=\"what-to-do-if-you-experience-heat-intolerance\">What to do if you experience heat intolerance<\/h2>\n<p>When these signs appear, take steps to go indoors and cool off as soon as possible. Remove excess clothing, drink cool water, and apply cool compresses to your body.\u00a0<\/p>\n<p>If you remain in the heat, you could develop symptoms such as rapid breathing, decreased sweating, or altered mental state. \u201cA person should seek medical care if they are experiencing the aforementioned symptoms,\u201d Dr. Puopolo says. These symptoms can mean that your heat intolerance is progressing to a heat-related illness, such as heat stroke, which may be fatal when untreated.<\/p>\n<h2 id=\"how-to-prevent-heat-intolerance\">How to prevent heat intolerance<\/h2>\n<p>Prevention is always the best treatment. If you are on any of the medications known to increase the risk of heat intolerance, take extra precautions before you head outdoors:<\/p>\n<ul>\n<li>Carry water with you and drink it regularly to stay hydrated.<\/li>\n<li>Wear a hat to keep excess sun off your body.<\/li>\n<li>Avoid spending prolonged periods outdoors during the heat of the day.<\/li>\n<li>Wear loose-fitting, lightweight clothing.<\/li>\n<li>Avoid exerting yourself too much when it\u2019s hot.<\/li>\n<\/ul>\n<p>When in doubt, drink a glass of water and sit down for a minute indoors. If your symptoms don\u2019t subside quickly, it may be time to seek medical treatment. Be sure to keep a list of medications you are currently taking handy so that your treating healthcare provider can respond appropriately.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Summer is in full swing\u2014and there\u2019s another heat wave slamming your area. You\u2019re ready to hit the beach to cool off from the extreme heat. As long as you remember to reapply sunscreen and stay hydrated, you\u2019re enjoying the hot temperatures safely&#8230;right? Not so fast! If you take any daily pills\u2014prescription or over-the-counter\u2014check with your [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":51280,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8029],"tags":[788,8905],"coauthors":[9053],"class_list":["post-37393","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-education","tag-drug-safety","tag-seasonal","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.0 (Yoast SEO v28.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>14 types of medications that cause heat intolerance<\/title>\n<meta name=\"description\" content=\"Some meds increase dehydration and decrease sweat production. Check this list of medications that cause heat intolerance and stay safe this summer.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/medications-that-cause-heat-intolerance\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Can your Rx make you heat-sensitive?\" \/>\n<meta property=\"og:description\" content=\"Keep an eye out for these 14 types of medication\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/medications-that-cause-heat-intolerance\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-22T13:30:44+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-10T22:47:04+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/05\/Blog_070221_Medication_heat_stroke.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Leah Campbell\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Can your Rx make you heat-sensitive?\" \/>\n<meta name=\"twitter:description\" content=\"Keep an eye out for these 14 types of medication\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/05\/Blog_070221_Medication_heat_stroke.png\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Leah Campbell\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/\"},\"author\":{\"name\":\"Mariusz Labedzki\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/232380d21234706e6360acfa9c895934\"},\"headline\":\"14 medications that make you sensitive to the heat\",\"datePublished\":\"2021-07-22T13:30:44+00:00\",\"dateModified\":\"2026-07-10T22:47:04+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/\"},\"wordCount\":1848,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/Blog_070221_Medication_heat_stroke.png\",\"keywords\":[\"Drug safety\",\"Seasonal\"],\"articleSection\":[\"Health Education\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/\",\"name\":\"14 types of medications that cause heat intolerance\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/medications-that-cause-heat-intolerance\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/05\\\/Blog_070221_Medication_heat_stroke.png\",\"datePublished\":\"2021-07-22T13:30:44+00:00\",\"dateModified\":\"2026-07-10T22:47:04+00:00\",\"description\":\"Some meds increase dehydration and decrease sweat production. 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