{"id":38274,"date":"2021-08-05T09:00:12","date_gmt":"2021-08-05T13:00:12","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=38274"},"modified":"2024-09-19T11:57:06","modified_gmt":"2024-09-19T15:57:06","slug":"mirtazapine-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/","title":{"rendered":"Mirtazapine side effects and how to avoid them"},"content":{"rendered":"<p><a href=\"#side-effects\">Mirtazapine side effects<\/a> | <a href=\"#suicide\">Suicide<\/a> | <a href=\"#serotonin-syndrome\">Serotonin syndrome<\/a> | <a href=\"#angle-closure-glaucoma\">Angle-closure glaucoma<\/a> | <a href=\"#weight-changes\">Weight changes<\/a> | <a href=\"#how-long-do-side-effects-last\">How long do side effects last?<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a><\/p>\n<p><span style=\"font-weight: 400;\">Mirtazapine (brand names: Remeron and Remeron SolTab) is a generic prescription drug used to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">major depressive disorder<\/span><\/a><span style=\"font-weight: 400;\"> (MDD) in adults. Mirtazapine is classified as an atypical or tetracyclic <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">antidepressant<\/span><\/a><span style=\"font-weight: 400;\">. The exact way in which mirtazapine works is not clear. However, it is believed to increase the production of two neurotransmitters in the brain, serotonin, and norepinephrine. These neurotransmitters activate nerve pathways involved with mood, anxiety, and other emotions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although it is considered a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5972123\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">highly effective antidepressant<\/span><\/a><span style=\"font-weight: 400;\">, mirtazapine does cause side effects. Some side effects can be mild while others can affect your daily quality of life and lead to serious complications. Before taking mirtazapine, take some time to review its side effects, drug interactions, and warnings, as well as potential ways to minimize problems when taking this drug.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/mirtazapine\/what-is\"><b>Learn more about mirtazapine<\/b><\/a><\/p>\n<h2 id=\"side-effects\">Common side effects of mirtazapine<\/h2>\n<p><span style=\"font-weight: 400;\">The most common side effects of mirtazapine <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/117105\/mirtazapine\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">include<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sleepiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/high-triglycerides-treatment-options\/\"><span style=\"font-weight: 400;\">High triglyceride levels<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal dreams<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal thoughts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the hands and feet<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated liver enzymes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Frequent urination<\/span><\/li>\n<\/ul>\n<h2>Serious side effects of mirtazapine<\/h2>\n<p><span style=\"font-weight: 400;\">Mirtazapine can cause serious side effects including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suicidal thoughts and behaviors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Worsening of depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Serotonin syndrome<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low white blood cell counts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mania or hypomania<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Angle-closure glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low sodium levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in heart rhythm<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle damage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe skin reactions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Withdrawal symptoms upon discontinuation of the medicine<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Mental Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"suicide\">Mirtazapine and suicide<\/h2>\n<p><span style=\"font-weight: 400;\">Mirtazapine, like other antidepressants, carries an increased risk of causing worsened depression and provoking suicidal behaviors in children, teens, and young adults. For antidepressants in general, there is an increased <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=711aa80b-8fc6-49e6-9494-3db31d9b53a4#ID_19552647-d1b1-40c0-952d-633a01e92be5\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">suicide risk<\/span><\/a><span style=\"font-weight: 400;\"> of 1.4% in patients younger than 18 and 0.5% in patients aged 18 to 24. However, people older than 24 taking antidepressants are at a lower risk of suicidality than patients not taking antidepressants. All people on mirtazapine should be watched for signs of suicidality such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suicide attempts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thoughts about suicide or death<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">New or worse depression, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/anxiety-treatment-and-medications\"><span style=\"font-weight: 400;\">anxiety<\/span><\/a><span style=\"font-weight: 400;\">, or irritability<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Panic attacks<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aggressive behaviors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual behaviors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Risk-taking behaviors<\/span><\/li>\n<\/ul>\n<h2 id=\"serotonin-syndrome\">Mirtazapine and serotonin syndrome<\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/serotonin-syndrome-symptoms\/\"><span style=\"font-weight: 400;\">Serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\"> is a rare condition that can develop when more than one serotonergic drug is being taken at the same time, causing high levels of serotonin in the brain. In most cases, symptoms will be mild and the condition will pass in a few days after the drugs are stopped. Severe cases, however, can be life-threatening. Get medical help if you experience any <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=98ad1917-a094-44f5-a28f-a64a8cfcd887\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">signs of serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\"> such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Agitation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of coordination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased sweating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin flushing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea or vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rigid muscles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hallucinations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coma<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Mirtazapine and low white blood cell counts<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Mirtazapine, like other antidepressants, often causes a decrease in white blood cells. White blood cells fight off infections and cancers, so low white blood cell counts leave patients vulnerable to infections. Consult a healthcare provider immediately if you notice signs of infection such as:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flu-like symptoms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chills<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/sore-throat-treatment-and-medications\"><span style=\"font-weight: 400;\">Sore throat<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mouth sores<\/span><\/li>\n<\/ul>\n<h2 id=\"angle-closure-glaucoma\">Mirtazapine and angle-closure glaucoma<\/h2>\n<p><a href=\"https:\/\/www.health.harvard.edu\/diseases-and-conditions\/narrow_angles_a_tip-off_to_eyesight_risk\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Angle-closure glaucoma<\/span><\/a><span style=\"font-weight: 400;\"> is a serious condition that happens suddenly and can quickly cause serious or total vision loss. People with uncorrected \u201cnarrow angles\u201d between the iris and the cornea, the area that drains fluid from the eye, are most vulnerable. Mirtazapine can cause this \u201cnarrow angle\u201d to close, resulting in a rapid build-up of fluid in the eye. Immediately stop using the medication and go to an emergency room if you experience signs of angle-closure glaucoma such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eye pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vision changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling or redness in or around the eye<\/span><\/li>\n<\/ul>\n<h2 id=\"weight-changes\">Mirtazapine and weight changes<\/h2>\n<p><span style=\"font-weight: 400;\">Two of the most common side effects of mirtazapine are increased appetite and weight gain. In clinical trials, <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=711aa80b-8fc6-49e6-9494-3db31d9b53a4\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">17%<\/span><\/a><span style=\"font-weight: 400;\"> of participants experienced increased appetite and 12% gained weight. If weight gain is noticed while taking mirtazapine, get advice from your healthcare provider. Managing weight may require dietary and lifestyle changes.<\/span><\/p>\n<h2 id=\"how-long-do-side-effects-last\">How long do side effects last?<\/h2>\n<p><span style=\"font-weight: 400;\">Most common side effects of mirtazapine are temporary. They usually go away as your body adjusts to the medication after a few days to a couple of weeks. Severe side effects can take weeks to resolve and should be managed by a healthcare provider. Left untreated, severe side effects like angle-closure glaucoma could have lifelong consequences.\u00a0<\/span><\/p>\n<h2 id=\"warnings\">Mirtazapine contraindications &amp; warnings<\/h2>\n<p><span style=\"font-weight: 400;\">Although mirtazapine is considered a highly effective antidepressant, not everyone should take it. Mirtazapine may worsen pre-existing medical conditions. Tell your doctor if you have a history of medical conditions like bipolar disorder, glaucoma, heart problems, seizures, high cholesterol levels, kidney or liver problems, or low blood pressure before starting treatment with mirtazapine.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The U.S. Food and Drug Administration (FDA) <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=13bb8267-1cab-43e5-acae-55a4d957630a\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">does not classify<\/span><\/a><span style=\"font-weight: 400;\"> mirtazapine as a controlled substance, meaning that it does not carry a high risk of abuse. Doctors are not advised to monitor patients for signs of mirtazapine abuse or diversion.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People who suddenly stop taking mirtazapine may experience withdrawal symptoms such as anxiety, agitation, dizziness, confusion, weird or prickling skin sensations, bizarre dreams, headache, sweating, nausea, and vomiting. When it\u2019s time to stop taking mirtazapine, a healthcare provider will prescribe a gradually tapering dose to prevent withdrawal.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">An overdose of mirtazapine can cause symptoms such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Disorientation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Impaired memory<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast heartbeat<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Seek emergency medical treatment if a mirtazapine overdose is suspected.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Restrictions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Because of the risk of severe allergic reactions, anyone with allergies to mirtazapine should not take the medication. Other people may experience side effects or other problems when taking mirtazapine, so the drug will be prescribed under the guidance of a healthcare provider.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Because of the risk of suicidal thoughts and behaviors, <\/span><b>people younger than the age of 25<\/b><span style=\"font-weight: 400;\"> taking mirtazapine should be monitored by healthcare providers and caretakers for signs of worsening depression or suicidality.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mirtazapine can provoke manic or hypomanic episodes in people with <\/span><b>bipolar disorder<\/b><span style=\"font-weight: 400;\">, so people with a history of mania will need to be watched for signs of mania or hypomania.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mirtazapine will require careful dosing and monitoring in people with <\/span><b>liver<\/b><span style=\"font-weight: 400;\">,<\/span><b> renal<\/b><span style=\"font-weight: 400;\">, or<\/span><b> heart problems<\/b><span style=\"font-weight: 400;\">. People with a history of unusual heart rhythms, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/congestive-heart-failure-treatment-and-medications\"><span style=\"font-weight: 400;\">congestive heart failure<\/span><\/a><span style=\"font-weight: 400;\">, or heart attack may require regular ECGs to keep track of mirtazapine\u2019s effects on the heart. In some cases, dosages may be modified.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mirtazapine may cause <\/span><b>low sodium levels<\/b><span style=\"font-weight: 400;\">, especially in the elderly, people taking diuretics, and those who have low blood volume. Electrolyte levels may need to be monitored to prevent adverse effects.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mirtazapine makes people more vulnerable to seizures, so people with <\/span><b>a history of seizures <\/b><span style=\"font-weight: 400;\">may require monitoring.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">People with<\/span><b> uncorrected narrow angles<\/b><span style=\"font-weight: 400;\"> are at a higher risk of narrow-angle glaucoma, so they should closely monitor any eye problems when taking mirtazapine.<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Pregnancy and nursing<\/span><\/h3>\n<p><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=711aa80b-8fc6-49e6-9494-3db31d9b53a4#ID_19552647-d1b1-40c0-952d-633a01e92be5\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">There is no evidence<\/span><\/a><span style=\"font-weight: 400;\"> that mirtazapine increases the risk of birth defects, miscarriage, or other problems when taken during pregnancy. However, mirtazapine should only be taken while pregnant if the potential benefits outweigh the potential risks.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although mirtazapine is present in breast milk in very small amounts, there is no evidence of any harm to a breastfeeding infant when the mother is taking mirtazapine. Consult a healthcare provider before taking mirtazapine while pregnant or breastfeeding.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The Food and Drug Administration (FDA) <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=7d6c31e2-b5a4-4279-8013-a8dad37ea73b\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">has not approved<\/span><\/a><span style=\"font-weight: 400;\"> mirtazapine as safe and effective for children. Mirtazapine may, however, be prescribed off-label to children if deemed appropriate by a healthcare provider. Antidepressants, however, are associated with a high risk of worsening depression and suicidality when given to children.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Mirtazapine should be used with caution in the elderly, and the lowest effective dose should be started if treatment with mirtazapine is recommended. Mirtazapine levels may be higher in the elderly than in other people, which can lead to an increased risk of drowsiness, confusion, and low sodium levels, among other side effects.<\/span><\/p>\n<h2 id=\"interactions\">Mirtazapine interactions<\/h2>\n<p><span style=\"font-weight: 400;\">Most mirtazapine drug interactions are minor. Some, however, can cause serious problems. For instance, there is an increased risk of severe or even life-threatening heart rhythm problems when mirtazapine is taken at the same time as the antipsychotic drugs <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/pimozide\"><span style=\"font-weight: 400;\">pimozide<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/thioridazine-hcl\"><span style=\"font-weight: 400;\">thioridazine<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><br \/>\n<span style=\"font-weight: 400;\">Mirtazapine should never be taken with monoamine oxidase inhibitors (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/maois\"><span style=\"font-weight: 400;\">MAOIs<\/span><\/a><span style=\"font-weight: 400;\">), a small family of drugs that includes the antidepressants isocarboxazid, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/phenelzine-sulfate\"><span style=\"font-weight: 400;\">phenelzine<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tranylcypromine-sulfate\"><span style=\"font-weight: 400;\">tranylcypromine<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/selegiline-hcl\"><span style=\"font-weight: 400;\">selegiline<\/span><\/a><span style=\"font-weight: 400;\">. Other MAOIs include the cancer drug <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/procarbazine-hcl\"><span style=\"font-weight: 400;\">procarbazine<\/span><\/a><span style=\"font-weight: 400;\">, the antibiotic <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/linezolid\"><span style=\"font-weight: 400;\">linezolid<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/methylene-blue\"><span style=\"font-weight: 400;\">methylene blue<\/span><\/a><span style=\"font-weight: 400;\">. Combining mirtazapine with MAOIs can cause severe serotonin syndrome.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other drugs, when combined with mirtazapine, can also cause serotonin syndrome. These drugs include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antidepressants such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prozac\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> (fluoxetine), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><span style=\"font-weight: 400;\"> (sertraline), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paxil\"><span style=\"font-weight: 400;\">Paxil<\/span><\/a><span style=\"font-weight: 400;\"> (paroxetine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anxiolytics\"><span style=\"font-weight: 400;\">Anxiolytics<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">Antipsychotics<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/opioids\"><span style=\"font-weight: 400;\">Opioids<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certain <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/migraine-treatment-and-medications\"><span style=\"font-weight: 400;\">migraine<\/span><\/a><span style=\"font-weight: 400;\"> drugs called triptans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Amphetamines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticonvulsants\"><span style=\"font-weight: 400;\">Seizure medications<\/span><\/a><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/carbamazepine\"><span style=\"font-weight: 400;\">carbamazepine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antiemetics\"><span style=\"font-weight: 400;\">Anti-nausea drugs<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs that treat Parkinson\u2019s disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Over-the-counter supplements such as St. John\u2019s wort<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Sedation is a very common side effect of mirtazapine. Combining mirtazapine with other drugs that slow down the central nervous system (CNS) can worsen side effects such as sleepiness and cognitive impairment. Drugs that can act as CNS depressants include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Alcohol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">Benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/valium\"><span style=\"font-weight: 400;\">Valium<\/span><\/a><span style=\"font-weight: 400;\"> (diazepam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/sleep-aids-guide\/\"><span style=\"font-weight: 400;\">Sleeping aids<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/barbiturates\"><span style=\"font-weight: 400;\">Barbiturates<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Antipsychotics\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anticonvulsants<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">This is not a complete list of drugs that can interact with mirtazapine. Medications that act as CYP3A4 inhibitors, like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ketoconazole\"><span style=\"font-weight: 400;\">ketoconazole<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clarithromycin\"><span style=\"font-weight: 400;\">clarithromycin<\/span><\/a><span style=\"font-weight: 400;\">, should also be avoided in combination with mirtazapine. Consult a healthcare provider for a complete list of possible drug interactions with mirtazapine.\u00a0<\/span><\/p>\n<h2 id=\"how-to-avoid-side-effects\">How to avoid mirtazapine side effects<\/h2>\n<p><span style=\"font-weight: 400;\">A few tips can help minimize possible side effects:<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">1. Take Mirtazapine as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Take mirtazapine tablets or orally-disintegrating tablets exactly as instructed. The typical dose is <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/320001\/Lexapro\/Adult-Dosing\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">15 to 45 mg<\/span><\/a><span style=\"font-weight: 400;\"> taken once at bedtime with or without food. Don\u2019t take extra medicine or skip a dose. Don\u2019t take extra medicine to make up for a missed dose.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2. Tell the healthcare provider about all medical conditions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Before taking mirtazapine, you should inform your healthcare provider about any medical conditions you have, especially:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any history of suicide or depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any history of mania, hypomania, or bipolar disorder<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart problems or irregular heartbeat, particularly QT prolongation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low sodium levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizure disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any history of stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High triglyceride levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy or pregnancy plans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breastfeeding or plans to breastfeed<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">3. Tell the healthcare provider about all medications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drug interactions can be a major cause of adverse effects, so any healthcare provider needs to know about all medications being taken. View the contraindications and interactions sections above to learn about some medications to avoid while using mirtazapine, then talk to your healthcare professional about steps to avoid any drug interactions.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Take mirtazapine at bedtime<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For maximum benefits, mirtazapine should be taken at the same time every day. Unless instructed otherwise, it\u2019s best to take mirtazapine at bedtime. Most people taking mirtazapine will experience sleepiness, so taking it at bedtime will help minimize interruptions in daily activities.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">5. Do not drink alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Combining alcohol with mirtazapine can worsen sleepiness and mental impairment caused by the drug. Avoid drinking if possible. It\u2019s also a good idea to stay away from medications that also cause sleepiness such as benzodiazepines.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">6. Be careful about driving and other risky activities<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Most people taking mirtazapine will experience some level of sedation or impairment. Driving while sedated is very risky, as is operating machinery or engaging in potentially hazardous activities that require focus, such as skiing. Take this medication for a week or two to see how this medication affects you. Then approach driving or other activities with care.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">7. Eat a healthy diet<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid weight gain, eat a healthy diet when taking mirtazapine. Lean protein can satisfy an increased appetite caused by mirtazapine without leading to weight gain. If you need help, it\u2019s a good idea to consult with a dietitian or nutritionist if appetite and weight changes become a problem while taking this medication.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">8. Do not stop taking mirtazapine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Suddenly stopping mirtazapine may cause withdrawal side effects. If you\u2019re thinking about discontinuing the use of mirtazapine, get medical advice before doing so. A healthcare professional will recommend a plan to wean you off the drug in order to prevent withdrawal.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Related resources for Lexapro side effects:<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/online.epocrates.com\/drugs\/117110\/mirtazapine\/Monograph\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Mirtazapine<\/span><\/a><span style=\"font-weight: 400;\">, Epocrates<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK519059\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Mirtazapine<\/span><\/a><span style=\"font-weight: 400;\">, StatPearls<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=711aa80b-8fc6-49e6-9494-3db31d9b53a4\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Mirtazapine tablets prescribing information,<\/span><\/a><span style=\"font-weight: 400;\"> U.S. National Library of Medicine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=98ad1917-a094-44f5-a28f-a64a8cfcd887\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Remeron\/Remeron SolTabs prescribing information,<\/span><\/a><span style=\"font-weight: 400;\"> U.S. National Library of Medicine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.health.harvard.edu\/diseases-and-conditions\/narrow_angles_a_tip-off_to_eyesight_risk\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">\u201cNarrow angles\u201d: A tip-off to eyesight risk<\/span><\/a><span style=\"font-weight: 400;\">, Harvard Health Publishing<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Mirtazapine side effects | Suicide | Serotonin syndrome | Angle-closure glaucoma | Weight changes | How long do side effects last? | Warnings | Interactions | How to avoid side effects Mirtazapine (brand names: Remeron and Remeron SolTab) is a generic prescription drug used to treat major depressive disorder (MDD) in adults. Mirtazapine is classified [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":38275,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[451,788,12752,450],"coauthors":[8861],"class_list":["post-38274","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-depression","tag-drug-safety","tag-medication-side-effects","tag-mental-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Mirtazapine side effects and safety information | SingleCare<\/title>\n<meta name=\"description\" content=\"Dizziness, constipation and weight gain are common mirtazapine side effects. Learn how long side effects of mirtazapine last and how to avoid them.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mirtazapine side effects and how to avoid them\" \/>\n<meta property=\"og:description\" content=\"Dizziness, constipation and weight gain are common mirtazapine side effects. Learn how long side effects of mirtazapine last and how to avoid them.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2021-08-05T13:00:12+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-09-19T15:57:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/07\/Mirtazapine-side-effects-and-how-to-avoid-them.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"SingleCare Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"SingleCare Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"10 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/\"},\"author\":{\"name\":\"SingleCare Team\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\"},\"headline\":\"Mirtazapine side effects and how to avoid them\",\"datePublished\":\"2021-08-05T13:00:12+00:00\",\"dateModified\":\"2024-09-19T15:57:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/\"},\"wordCount\":2080,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2021\\\/07\\\/Mirtazapine-side-effects-and-how-to-avoid-them.png\",\"keywords\":[\"Depression\",\"Drug safety\",\"Medication side effects\",\"Mental health\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/\",\"name\":\"Mirtazapine side effects and safety information | SingleCare\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2021\\\/07\\\/Mirtazapine-side-effects-and-how-to-avoid-them.png\",\"datePublished\":\"2021-08-05T13:00:12+00:00\",\"dateModified\":\"2024-09-19T15:57:06+00:00\",\"description\":\"Dizziness, constipation and weight gain are common mirtazapine side effects. Learn how long side effects of mirtazapine last and how to avoid them.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2021\\\/07\\\/Mirtazapine-side-effects-and-how-to-avoid-them.png\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2021\\\/07\\\/Mirtazapine-side-effects-and-how-to-avoid-them.png\",\"width\":1920,\"height\":1080,\"caption\":\"Mirtazapine side effects and safety information\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/mirtazapine-side-effects\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Mirtazapine side effects and how to avoid them\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"name\":\"The Checkup, a health blog by SingleCare\",\"description\":\"Read the latest in prescription, wellness, and healthcare news\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\",\"name\":\"SingleCare\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"width\":1200,\"height\":630,\"caption\":\"SingleCare\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/singlecare\",\"https:\\\/\\\/x.com\\\/SingleCare\",\"https:\\\/\\\/www.instagram.com\\\/singlecare\\\/?hl=en\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/singlecare\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCd9kiPIjCQw95-2BHCYePKA\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\",\"name\":\"SingleCare Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=gcda8e0f4c5718cb7f68c0ee812f6fafb\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g\",\"caption\":\"SingleCare Team\"},\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/author\\\/singlecareteam\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Mirtazapine side effects and safety information | SingleCare","description":"Dizziness, constipation and weight gain are common mirtazapine side effects. Learn how long side effects of mirtazapine last and how to avoid them.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/","og_locale":"en_US","og_type":"article","og_title":"Mirtazapine side effects and how to avoid them","og_description":"Dizziness, constipation and weight gain are common mirtazapine side effects. Learn how long side effects of mirtazapine last and how to avoid them.","og_url":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/","og_site_name":"The Checkup","article_publisher":"https:\/\/www.facebook.com\/singlecare","article_published_time":"2021-08-05T13:00:12+00:00","article_modified_time":"2024-09-19T15:57:06+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/07\/Mirtazapine-side-effects-and-how-to-avoid-them.png","type":"image\/png"}],"author":"SingleCare Team","twitter_card":"summary_large_image","twitter_creator":"@SingleCare","twitter_site":"@SingleCare","twitter_misc":{"Written by":"SingleCare Team","Est. reading time":"10 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#article","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/"},"author":{"name":"SingleCare Team","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/403ef50a9f402fb9ce49c429659555f5"},"headline":"Mirtazapine side effects and how to avoid them","datePublished":"2021-08-05T13:00:12+00:00","dateModified":"2024-09-19T15:57:06+00:00","mainEntityOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/"},"wordCount":2080,"commentCount":0,"publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/07\/Mirtazapine-side-effects-and-how-to-avoid-them.png","keywords":["Depression","Drug safety","Medication side effects","Mental health"],"articleSection":["Drug Info"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/","url":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/","name":"Mirtazapine side effects and safety information | SingleCare","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#primaryimage"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/07\/Mirtazapine-side-effects-and-how-to-avoid-them.png","datePublished":"2021-08-05T13:00:12+00:00","dateModified":"2024-09-19T15:57:06+00:00","description":"Dizziness, constipation and weight gain are common mirtazapine side effects. Learn how long side effects of mirtazapine last and how to avoid them.","breadcrumb":{"@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#primaryimage","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/07\/Mirtazapine-side-effects-and-how-to-avoid-them.png","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/07\/Mirtazapine-side-effects-and-how-to-avoid-them.png","width":1920,"height":1080,"caption":"Mirtazapine side effects and safety information"},{"@type":"BreadcrumbList","@id":"https:\/\/www.singlecare.com\/blog\/mirtazapine-side-effects\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.singlecare.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Mirtazapine side effects and how to avoid them"}]},{"@type":"WebSite","@id":"https:\/\/www.singlecare.com\/blog\/#website","url":"https:\/\/www.singlecare.com\/blog\/","name":"The Checkup, a health blog by SingleCare","description":"Read the latest in prescription, wellness, and healthcare news","publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.singlecare.com\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.singlecare.com\/blog\/#organization","name":"SingleCare","url":"https:\/\/www.singlecare.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","width":1200,"height":630,"caption":"SingleCare"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/singlecare","https:\/\/x.com\/SingleCare","https:\/\/www.instagram.com\/singlecare\/?hl=en","https:\/\/www.linkedin.com\/company\/singlecare\/","https:\/\/www.youtube.com\/channel\/UCd9kiPIjCQw95-2BHCYePKA"]},{"@type":"Person","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/403ef50a9f402fb9ce49c429659555f5","name":"SingleCare Team","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=gcda8e0f4c5718cb7f68c0ee812f6fafb","url":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/7c56ea35da6164263b446caa5424dd8beeb331518803b6043b40932812936fb2?s=96&d=mm&r=g","caption":"SingleCare Team"},"url":"https:\/\/www.singlecare.com\/blog\/author\/singlecareteam\/"}]}},"_links":{"self":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/38274","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/users\/15"}],"replies":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/comments?post=38274"}],"version-history":[{"count":0,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/38274\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media\/38275"}],"wp:attachment":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media?parent=38274"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/categories?post=38274"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/tags?post=38274"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/coauthors?post=38274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}