{"id":39731,"date":"2021-09-03T10:00:11","date_gmt":"2021-09-03T14:00:11","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=39731"},"modified":"2026-01-30T11:47:18","modified_gmt":"2026-01-30T16:47:18","slug":"eliquis-and-alcohol","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/eliquis-and-alcohol\/","title":{"rendered":"What happens when you mix Eliquis and alcohol?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">In the pharmacy where I work, I recently noticed a lot of prescriptions for the blood thinner Eliquis. It feels like it\u2019s flying off the shelves. I looked up the statistics, and it wasn\u2019t just my imagination. Eliquis was the 28th most prescribed drug in the U.S. in 2023, down one spot from the previous year when it ranked 27. (In 2014, it was number 308, so it\u2019s come a long way.) <\/span><\/p>\n<p><span style=\"font-weight: 400;\">In fact, there were more than 12 million prescriptions filled for Eliquis in 2018. This newer medication has nearly caught up to <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\"><span style=\"font-weight: 400;\">warfarin<\/span><\/a><span style=\"font-weight: 400;\">\u2014also known by its brand name Coumadin\u2014a classic blood thinner that\u2019s been used since 1954.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As prescriptions increase, so do patient questions, and one common query is, \u201cCan I mix Eliquis and alcohol?\u201d\u00a0 First, let\u2019s talk about the uses of Eliquis and other safety information.\u00a0<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Eliquis with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tEliquis 5 mg (28 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$155.92<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$155.92<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\" class=\"coupon-see-all-btn\">See Eliquis prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"what-is-eliquis\"><span style=\"font-weight: 400;\">What is Eliquis?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Eliquis is a blood thinner, also known as an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticoagulants\"><span style=\"font-weight: 400;\">anticoagulant<\/span><\/a><span style=\"font-weight: 400;\">, which reduces blood clotting. It contains the ingredient apixaban. Eliquis was approved in 2012 and has several <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=33a9046a-41cc-46c1-becc-2ff4d7d71538&amp;audience=consumer\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">indications<\/span><\/a><span style=\"font-weight: 400;\">. Eliquis can be used to:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lower the risk of stroke and embolism (blocking of an artery) in patients with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/atrial-fibrillation-treatment-and-medications\"><span style=\"font-weight: 400;\">nonvalvular atrial fibrillation<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prevent <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/deep-vein-thrombosis-treatment-and-medications\"><span style=\"font-weight: 400;\">deep vein thrombosis (DVT)<\/span><\/a><span style=\"font-weight: 400;\">, which can lead to <\/span><a href=\"https:\/\/medlineplus.gov\/pulmonaryembolism.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">pulmonary embolism (PE)<\/span><\/a><span style=\"font-weight: 400;\">, in patients who have had hip or knee replacement surgery.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treat DVT<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Treat PE<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decrease the risk of a recurrence of DVT and PE<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/eliquis-vs-xarelto\/\"><span style=\"font-weight: 400;\">Eliquis<\/span><\/a><span style=\"font-weight: 400;\"> is categorized as a Factor Xa inhibitor. Other medications in this category include <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/xarelto\"><span style=\"font-weight: 400;\">Xarelto<\/span><\/a><span style=\"font-weight: 400;\"> (rivaroxaban), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/savaysa\"><span style=\"font-weight: 400;\">Savaysa<\/span><\/a><span style=\"font-weight: 400;\"> (edoxaban), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/arixtra\"><span style=\"font-weight: 400;\">Arixtra<\/span><\/a><span style=\"font-weight: 400;\"> (fondaparinux). Factor Xa inhibitors have an anticoagulation effect by blocking factor Xa, which therefore helps decrease blood clot production.\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-39862 size-full\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/08\/Mixup_Chart_090321.png\" alt=\"Eliquis and alcohol: A chart showing how dangerous the interaction\" width=\"1920\" height=\"900\" srcset=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/08\/Mixup_Chart_090321.png 1920w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/08\/Mixup_Chart_090321-300x141.png 300w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/08\/Mixup_Chart_090321-1024x480.png 1024w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/08\/Mixup_Chart_090321-768x360.png 768w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2021\/08\/Mixup_Chart_090321-1536x720.png 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/><\/p>\n<h2 id=\"what-are-the-side-effects-of-eliquis\"><span style=\"font-weight: 400;\">What are the side effects of Eliquis?\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most common <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/655105\/Eliquis\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Eliquis are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding (signs of bleeding may include easy bruising, bleeding gums, or nosebleeds)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low red blood cells (anemia)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of Eliquis may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fainting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypersensitivity reaction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding between the brain and skull (epidural hematoma)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">An accumulation of blood that can compress the spinal cord (spinal hematoma)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low platelet count (thrombocytopenia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Formation of blood clots (thrombosis) if the medication is stopped too soon<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Eliquis has a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">boxed, or black box, warning<\/span><\/a><span style=\"font-weight: 400;\">. This is the strongest warning required by the FDA. The warning includes risks such as epidural or spinal hematoma (which could result in paralysis). It recommends not stopping Eliquis before completing therapy, and avoiding anti-inflammatory drugs, other blood thinners, and platelet inhibitors to decrease risk.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Taking Eliquis puts you at increased risk for bleeding. Eliquis can cause serious, life-threatening, or even fatal bleeding. Taking Eliquis with other medications that affect bleeding\/clotting increases the risk even further. This includes other anticoagulants\u2014such as warfarin, Pradaxa (dabigatran), Brilinta, (ticagrelor), or heparin, or nonsteroidal anti-inflammatory drugs (NSAIDs). Signs and symptoms of blood loss indicate a medical emergency and should receive emergency medical attention.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Eliquis also has other warnings, side effects, and drug interactions. Before taking Eliquis, talk to your healthcare provider about all of your medical conditions and medical history to make sure Eliquis is safe for you. Tell your physician about all of the medications you take, including prescription medicines, over-the-counter drugs, and vitamins or supplements.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our heart health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Heart Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"can-you-mix-eliquis-and-alcohol\"><span style=\"font-weight: 400;\">Can you mix Eliquis and alcohol?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The prescribing information for Eliquis does not warn against alcohol use. Does this mean you\u2019re free to imbibe? Not quite yet. Since Eliquis is a blood thinner and alcohol may act as a blood thinner, it is best to avoid alcohol intake (unless your healthcare provider gives you the green light to drink a <\/span><a href=\"https:\/\/www.niaaa.nih.gov\/alcohol-health\/overview-alcohol-consumption\/moderate-binge-drinking\"><span style=\"font-weight: 400;\">small to moderate amount<\/span><\/a><span style=\"font-weight: 400;\">). This goes for all of the drugs in the class of Factor Xa inhibitors (Eliquis, Xarelto, Savaysa, Arixtra).<\/span><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3785645\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">One study<\/span><\/a><span style=\"font-weight: 400;\"> concluded that in patients who took an anticoagulant and had alcohol abuse problems, \u201canticoagulation control is particularly poor.\u201d Major hemorrhages were more common in this group.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Too much alcohol can contribute to many diseases of organs such as the liver, heart, and pancreas and is a factor in developing heart disease. Consuming more than two servings of alcohol every day can increase the risk of developing blood clots. This could theoretically work against Eliquis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Generally speaking, The American Blood Clot Association recommends that anyone with a clotting disorder or heart disease should use extreme caution when drinking. Inability to clot properly can be very dangerous.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/cardiac-arrest-vs-heart-attack\/\"><b>Cardiac arrest vs. heart attack<\/b><\/a><\/p>\n<h2 id=\"bottoms-up\"><span style=\"font-weight: 400;\">Bottoms up?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although the prescribing information for Eliquis does not explicitly warn against consuming alcohol, there are many individual factors that can affect a person\u2019s reaction to Eliquis and drinking alcohol. Long-term excessive alcohol consumption can also <\/span><span style=\"font-weight: 400;\">cause complications<\/span><span style=\"font-weight: 400;\"> such as cardiovascular disease, high blood pressure, and stroke.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Check in with your healthcare provider, who can evaluate your unique situation and provide medical advice on the risk of mixing alcohol and Eliquis. Based on your medical history, risk factors, medical conditions, and medications you take, your healthcare may allow for moderate alcohol consumption or advise you to avoid alcohol altogether.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In the pharmacy where I work, I recently noticed a lot of prescriptions for the blood thinner Eliquis. It feels like it\u2019s flying off the shelves. I looked up the statistics, and it wasn\u2019t just my imagination. Eliquis was the 28th most prescribed drug in the U.S. in 2023, down one spot from the previous [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":39848,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8029],"tags":[8742,788],"coauthors":[10668],"class_list":["post-39731","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-education","tag-alcohol-interactions","tag-drug-safety","franchise-the-mix-up","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What happens when you mix Eliquis and alcohol?<\/title>\n<meta name=\"description\" content=\"Moderate alcohol intake can act as a blood thinner. Since Eliquis is an anticoagulant, it&#039;s best to avoid mixing Eliquis and alcohol. 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Since Eliquis is an anticoagulant, it's best to avoid mixing Eliquis and alcohol. 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