{"id":41465,"date":"2021-09-16T10:05:44","date_gmt":"2021-09-16T14:05:44","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=41465"},"modified":"2024-09-09T16:30:07","modified_gmt":"2024-09-09T20:30:07","slug":"flu-cold-medicine-interactions","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/flu-cold-medicine-interactions\/","title":{"rendered":"Take this, not that? Be aware of cold and flu medicine interactions"},"content":{"rendered":"

Colds and flu are most common from September through May, but they can happen any time of year. If you start sniffling and sneezing, you might want to start thinking about the medications to treat cold symptoms and other respiratory ailments. But be cautious about potential cold and flu medicine interactions because you might not realize that certain drugs don\u2019t mix well.<\/span>\u00a0<\/span><\/p>\n

According to the U.S. Food and Drug Administration (FDA)<\/span><\/a>, a drug-drug interaction occurs when two or more medications interact with each other. One very common type of drug-drug interaction is a cold medicine interaction. This can happen when you take a cold or flu medication that interferes with the action of another medicine that you\u2019re taking, or when you take multiple medications that cause side effects when combined. Some products contain one or two active ingredients, where others contain three or four. This is why it\u2019s important to understand each ingredient.<\/span><\/p>\n

Common ingredients in many cold and flu medications<\/span><\/h2>\n

The next time you\u2019re shopping for a cold and flu medication for yourself, take a good long look at the list of ingredients. (The American Academy of Pediatrics recommends against giving children younger than 4 over-the-counter cold and cough medications, which contain the ingredients below, except for acetaminophen or ibuprofen for fever and pain.)\u00a0<\/span><\/p>\n

Although the specific combination of ingredients will vary from product to product, common ingredients in over-the-counter medications include:<\/span><\/p>\n

Acetaminophen<\/span><\/h3>\n

Commonly known by its brand name, Tylenol, <\/span>acetaminophen<\/span><\/a> is a pain reliever and reduces fever.\u00a0<\/span><\/p>\n

See acetaminophen interactions here<\/span><\/a>.<\/span><\/p>\n

Chlorpheniramine maleate<\/span><\/h3>\n

Chlorpheniramine<\/span><\/a> is an antihistamine that reduces cold and allergy symptoms and can be found in OTC medications such as Chlor-Trimeton and Chlor-Tabs.<\/span><\/p>\n

See chlorpheniramine interactions here.<\/span><\/a><\/p>\n

Diphenhydramine<\/span><\/h3>\n

Diphenhydramine is an antihistamine that treats runny noses, sneezing, and itchy, watery eyes. It is the generic name for <\/span>Benadryl<\/span><\/a> allergy medicine.<\/span><\/p>\n

See diphenhydramine interactions here<\/span><\/a>.<\/span><\/p>\n

Dextromethorphan<\/span><\/h3>\n

This ingredient, which belongs to a class of drugs known as antitussives, helps suppress your cough. You can find it in OTC products like <\/span>Delsym<\/span><\/a>,<\/span> Robitussin<\/span><\/a>,<\/span> Dayquil<\/span><\/a> Complete, Tylenol Cold Multi-Symptom formulations, and others.\u00a0<\/span><\/p>\n

See dextromethorphan interactions here<\/span><\/a>.<\/span><\/p>\n

Guaifenesin<\/span><\/h3>\n

Guaifenesin is an expectorant\u2014that is, it thins and loosens mucus to make it easier to cough up and out of your body. It does not decrease the amount of secretions, it just makes them thinner. It\u2019s the generic form of<\/span> Mucinex<\/span><\/a> and is a component in DayQuil Complete and Robitussin Severe Multi-Symptom Cough Cold and Flu.<\/span><\/p>\n

See guaifenesin interactions here<\/span><\/a>.<\/span><\/p>\n

Phenylephrine<\/span><\/h3>\n

This ingredient relieves nasal congestion, sinus congestion, and pain. It can be found in <\/span>Sudafed<\/span><\/a> PE (not just plain Sudafed, as it contains pseudoephedrine),<\/span> NyQuil Severe<\/span><\/a>, and other similar OTC products.\u00a0<\/span><\/p>\n

See phenylephrine interactions here<\/span><\/a>.<\/span><\/p>\n

Pseudoephedrine<\/span><\/h3>\n

Pseudoephedrine is another common nasal decongestant found in products like<\/span> Chlor Trimeton<\/span><\/a> Nasal Decongestant and various Sudafed formulations.<\/span><\/p>\n

See pseudoephedrine interactions here<\/span><\/a>.<\/span><\/p>\n

Watch out for doubling up<\/span>\u00a0<\/span><\/h2>\n

When you feel a cold coming on, your first instinct may be to purchase some medication to address your symptoms. Stop and read the label on each package before you buy anything. Many popular cold and flu medications do contain more than one active ingredient in an attempt to control multiple symptoms at once. In theory, that should simplify the process.<\/span><\/p>\n

\u201cHowever, sometimes this convenience is confusing because it may seem like you need two separate medications to cover all your symptoms,\u201d says<\/span> Danielle Carter<\/span><\/a>, MD, a family physician at Ascension St. Vincent\u2019s Riverside in Jacksonville, Florida, and new physician member of the American Academy of Family Physicians Board of Directors. \u201cUnfortunately, this can easily lead to accidentally \u2018doubling up\u2019 on specific ingredients that can cause side effects that can range from uncomfortable to dangerous.\u201d<\/span>\u00a0<\/span><\/p>\n

For example, consider the possibility of a Nyquil interaction. Here\u2019s how that could happen: You might pick up a product like Nyquil, Dayquil, or Theraflu, all of which contain acetaminophen in addition to other ingredients. But if you\u2019re already taking Tylenol, you could wind up with a double dose of acetaminophen. That could lead to side effects like cramping, loss of appetite, nausea, and stomach pain. \u201cSo it is important to consult the label before buying or taking anything,\u201d adds <\/span>David Cutler<\/span><\/a>, MD, a family medicine physician at Providence Saint John\u2019s Health Center in Santa Monica, California.\u00a0<\/span><\/p>\n

Other potential interactions to consider<\/span><\/h2>\n

It\u2019s not just cold medicine interactions that you need to be cautious about. Consider all medications, including both OTC and prescription (and other treatments) that you are taking. Interactions can occur between them and any cold and flu drugs you take.\u00a0<\/span><\/p>\n

So, it\u2019s a good rule of thumb to check out the potential interactions of any medication you\u2019re taking or planning to take. \u201cBefore taking anything over the counter, make sure your healthcare provider or pharmacist is aware of all the medications you\u2019re taking,\u201d says functional medicine practitioner <\/span>Christine Manukyan<\/span><\/a>, Pharm.D. \u201cFor example, someone with recent internal bleeding due to taking a blood thinner like warfarin\/coumadin should not take any cold and flu medications that may increase the risk of bleeding such as ibuprofen.\u201d<\/span><\/p>\n

Other treatments that you might be taking:\u00a0<\/span><\/p>\n

Antidepressants and dextromethorphan or pseudoephedrine<\/span><\/h3>\n

It\u2019s generally considered safe to take antidepressants while taking cold medicine. \u201cHowever, cold\/flu medications that contain <\/span>dextromethorphan<\/b> may increase the risk of a rare side effect called serotonin syndrome when taken with <\/span>SSRIs<\/span><\/a> and <\/span>SNRIs<\/span><\/a>,\u201d Dr. Carter says. \u201cSince there are many OTC options that do not contain that ingredient, it is probably best to avoid it just to be cautious.\u201d Dr. Manukyan also cautions that you should avoid mixing products containing <\/span>pseudoephedrine<\/b> if you\u2019re taking an older type of antidepressant known as a <\/span>monoamine oxidase inhibitor (MAOI)<\/span><\/a>, as it could cause a hypertensive crisis.<\/span><\/p>\n

Anti-hypertensives and pseudoephedrine<\/span><\/h3>\n

\u201cThe concern with OTC cough\/cold medications and high blood pressure is that the medications may further raise your blood pressure,\u201d says Dr. Carter. \u201cThe ingredient most likely to do this is <\/span>pseudoephedrine<\/b>, but you should also use caution with some nasal sprays.\u201d Your healthcare provider might suggest choosing an OTC product with phenylephrine instead.\u00a0<\/span><\/p>\n

Elderberry and immunosuppressants<\/span><\/h3>\n

Elderberry products aren\u2019t technically medication, as they\u2019re considered supplements, but many people turn to them when cold and flu season approaches. \u201cElderberry is safe and effective for many patients, except for those who are taking medications to suppress their immune system, i.e., <\/span>immunosuppressants<\/b>,\u201d says Dr. Manukyan. \u201cMedications that decrease the immune system interact with elderberry.\u201d She cautions that elderberry-drug interactions could potentially occur as a result of taking elderberry along with corticosteroids like prednisone, as well as cyclosporine and other immunosuppressants.<\/span><\/p>\n

Tamiflu<\/span><\/h3>\n

Should you be concerned about a Tamiflu drug interaction if your healthcare provider prescribes this antiviral in the early stages of a case of influenza? \u201cLuckily, Tamiflu does not interact with the ingredients of most over-the-counter cold and flu medications,\u201d says Dr. Carter.<\/span><\/p>\n

Other considerations when taking cold meds<\/span>\u00a0<\/span><\/h2>\n

Another consideration: Some meds contain added colors and flavorings. \u201cMake sure to mention all your allergies to your pharmacist when picking over-the-counter cold and flu medication,\u201d says Dr. Manukyan.<\/span><\/p>\n

\u00a0<\/span>Also, it\u2019s probably best to<\/span> avoid drinking alcohol when taking any cold or flu medications<\/span><\/a>. Alcohol can increase the effect of ingredients like dextromethorphan, and it can compound the sedative effect of antihistamines. Plus, many cold meds contain acetaminophen, which could potentially lead to liver damage if mixed with alcohol.<\/span><\/p>\n

\u00a0<\/span>\u201cThe overall advice I would give before taking medication for colds or flu is to balance the benefits against the risks,\u201d Dr. Cutler says. \u201cDoing so may make mom\u2019s chicken soup seem like the best medicine of all.\u201d<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Colds and flu are most common from September through May, but they can happen any time of year. If you start sniffling and sneezing, you might want to start thinking about the medications to treat cold symptoms and other respiratory ailments. But be cautious about potential cold and flu medicine interactions because you might not […]<\/p>\n","protected":false},"author":94,"featured_media":629691,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[11169,814,20954,8905],"coauthors":[9482],"class_list":["post-41465","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-cold-flu","tag-drug-interactions","tag-infections","tag-seasonal","wpautop"],"acf":[],"yoast_head":"\nCold and flu medicine interactions to be cautious of<\/title>\n<meta name=\"description\" content=\"Cold and flu meds can contain multiple ingredients, which can lead to 'doubling up' on other meds like Tylenol. 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