{"id":4191,"date":"2019-05-23T16:42:24","date_gmt":"2019-05-23T20:42:24","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=4191"},"modified":"2024-08-12T12:27:35","modified_gmt":"2024-08-12T16:27:35","slug":"remicade-vs-humira","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/remicade-vs-humira\/","title":{"rendered":"Remicade vs. Humira: Differences, similarities, and which is better for you"},"content":{"rendered":"<p><a href=\"#drug-overview-differences\">Drug overview &amp; main differences<\/a> | <a href=\"#conditions-treated\">Conditions treated<\/a> | <a href=\"#efficacy\">Efficacy<\/a> | <a href=\"#insurance-coverage-cost-comparison\">Insurance coverage and cost comparison<\/a> | <a href=\"#side-effects\">Side effects<\/a> | <a href=\"#drug-interactions\">Drug interactions<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#FAQ\">FAQ<\/a><\/p>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are two brand-name medications used for <\/span><a href=\"https:\/\/www.cdc.gov\/ibd\/what-is-IBD.htm\"><span style=\"font-weight: 400;\">inflammatory bowel disease<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ibd-vs-ibs\/\"><span style=\"font-weight: 400;\">IBD<\/span><\/a><span style=\"font-weight: 400;\">, which includes <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ulcerative-colitis-vs-crohns\/\"><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">ulcerative colitis<\/span><\/a><span style=\"font-weight: 400;\">) rheumatoid arthritis<\/span><span style=\"font-weight: 400;\">, and various other <\/span><span style=\"font-weight: 400;\">autoimmune diseases<\/span><span style=\"font-weight: 400;\">. You may have heard of these drugs in the news. <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> is made by AbbVie, and has been the world\u2019s <\/span><a href=\"https:\/\/www.fiercepharma.com\/special-report\/top-20-drugs-by-2020-sales-humira\"><span style=\"font-weight: 400;\">top-selling drug<\/span><\/a><span style=\"font-weight: 400;\"> since 2012. <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> is made by <\/span><span style=\"font-weight: 400;\">Janssen<\/span><span style=\"font-weight: 400;\"> Biotech, Inc.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are prescription drugs approved by the U.S. <\/span><span style=\"font-weight: 400;\">Food and Drug Administration<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">). They are known as <\/span><span style=\"font-weight: 400;\">biologics<\/span><span style=\"font-weight: 400;\"> and are <\/span><span style=\"font-weight: 400;\">monoclonal antibodies<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are in a drug class called <\/span><span style=\"font-weight: 400;\">tumor necrosis factor<\/span><span style=\"font-weight: 400;\"> blockers, or <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\">. They <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/postmarket-drug-safety-information-patients-and-providers\/information-tumor-necrosis-factor-tnf-blockers-marketed-remicade-enbrel-humira-cimzia-and-simponi\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">work by<\/span><\/a><span style=\"font-weight: 400;\"> blocking the activity of <\/span><span style=\"font-weight: 400;\">tumor necrosis factor<\/span><span style=\"font-weight: 400;\">, or <\/span><span style=\"font-weight: 400;\">TNF<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">TNF<\/span><span style=\"font-weight: 400;\"> is a substance in the body that can cause inflammation and lead to various diseases related to the <\/span><span style=\"font-weight: 400;\">immune system<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\">, also called <\/span><span style=\"font-weight: 400;\">TNF inhibitors<\/span><span style=\"font-weight: 400;\">, suppress the <\/span><span style=\"font-weight: 400;\">immune system<\/span><span style=\"font-weight: 400;\">, blocking the activity of <\/span><span style=\"font-weight: 400;\">TNF<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although both <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are both <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\">, they do have some differences. Continue reading below to learn about <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2 id=\"drug-overview-differences\">What are the main differences between Remicade vs. Humira<\/h2>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are both <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\">, also known as <\/span><span style=\"font-weight: 400;\">TNF-alpha<\/span><span style=\"font-weight: 400;\"> blockers. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/remicade\/what-is\"><span style=\"font-weight: 400;\">Remicade<\/span><\/a><span style=\"font-weight: 400;\"> contains the ingredient <\/span><span style=\"font-weight: 400;\">infliximab<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> is given as an IV infusion (into a vein) by a <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/humira\/what-is\"><span style=\"font-weight: 400;\">Humira<\/span><\/a><span style=\"font-weight: 400;\"> contains the ingredient <\/span><span style=\"font-weight: 400;\">adalimumab<\/span><span style=\"font-weight: 400;\">. It is available as a pen injection or a prefilled syringe injection and is given subcutaneously (under the skin of the thigh or stomach). After proper training, <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> can be self-injected by the patient, or administered by a caregiver.\u00a0<\/span><\/p>\n<table class=\"singlecare-table\">\n<thead>\n<tr>\n<th><span class=\"title\">Main differences between Remicade and Humira<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Remicade<\/b><b>\u00a0<\/b><\/td>\n<td><b>Humira<\/b><b>\u00a0<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Tumor necrosis factor-alpha<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">TNF-alpha<\/span><span style=\"font-weight: 400;\">) blocker<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Tumor necrosis factor-alpha<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">TNF-alpha<\/span><span style=\"font-weight: 400;\">) blocker<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Infliximab<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adalimumab<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Intravenous infusion<\/span><span style=\"font-weight: 400;\"> by a <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Subcutaneous<\/span><span style=\"font-weight: 400;\"> injection (pen or prefilled syringe) by patient or caregiver<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children (age of child depends on indication; not every indication is approved for children)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children (age of child depends on indication; not every indication is approved for children)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"conditions-treated\">Conditions treated by Remicade and Humira<\/h2>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> is approved for the treatment of:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> in adults and children 6 years and older who have not adequately responded to conventional therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to <\/span><span style=\"font-weight: 400;\">severe ulcerative colitis<\/span><span style=\"font-weight: 400;\"> in adults and children 6 years and older who have not adequately responded to conventional therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/osteoarthritis-vs-rheumatoid-arthritis\/\" target=\"_blank\" rel=\"noopener\">Rheumatoid arthritis<\/a><span style=\"font-weight: 400;\"> (in adults with moderately to severely active disease; in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/ankylosing-spondylitis-diet\/\">Ankylosing spondylitis<\/a><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/types-of-arthritis\/\">Psoriatic arthritis<\/a><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\">Plaque psoriasis<span style=\"font-weight: 400;\"> in adults with chronic, severe disease which is extensive and\/or disabling<\/span><\/li>\n<\/ul>\n<p>Humira<span style=\"font-weight: 400;\"> is approved for the treatment of:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> in adults and children 6 years and older who have not adequately responded to conventional therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to <\/span><span style=\"font-weight: 400;\">severe ulcerative colitis<\/span><span style=\"font-weight: 400;\"> in adults and children 5 years and older who have not adequately responded to conventional therapy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rheumatoid arthritis<\/span><span style=\"font-weight: 400;\"> (in adults with moderately to severely active disease; in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\"> or other non-<\/span><span style=\"font-weight: 400;\">biologi<\/span><span style=\"font-weight: 400;\">c<\/span><span style=\"font-weight: 400;\"> disease-modifying anti-rheumatic drugs, or <\/span><a href=\"https:\/\/www.arthritis.org\/drug-guide\/dmards\/dmards\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">DMARDs<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psoriatic arthritis<\/span><span style=\"font-weight: 400;\"> in adults (alone or in combination with non-<\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\"> DMARDs)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ankylosing spondylitis<\/span><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe chronic <\/span><span style=\"font-weight: 400;\">plaque psoriasis<\/span> <span style=\"font-weight: 400;\">in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Juvenile idiopathic arthritis<\/span><span style=\"font-weight: 400;\"> (JIA) in adults and children ages 2 years and older with moderate to severely active JIA (alone or in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hidradenitis suppurativa in moderate to severe cases in adults and children ages 12 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uveitis in adults and children ages 2 years and older<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> is generally taken in combination with other medications for the condition being treated. For example, a patient with <\/span><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><span style=\"font-weight: 400;\"> may also be taking <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">, folic acid, <\/span><span style=\"font-weight: 400;\">corticosteroids<\/span><span style=\"font-weight: 400;\">, and\/or nonsteroidal anti-inflammatory drugs (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">). A patient with <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> may also be taking antibiotics, antivirals, <\/span><span style=\"font-weight: 400;\">corticosteroids<\/span><span style=\"font-weight: 400;\">, aminosalicylates, and <\/span><span style=\"font-weight: 400;\">azathioprine<\/span><span style=\"font-weight: 400;\"> or mercaptopurine.<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr class=\"header-row\">\n<td><b>Condition<\/b><\/td>\n<td><b>Remicade<\/b><b>\u00a0<\/b><\/td>\n<td><b>Humira<\/b><b>\u00a0<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 6 years and older)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 6 years and older)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Ulcerative colitis<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 6 years and older)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 5 years and older)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Rheumatoid arthritis<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults; in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults; alone or in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\"> or other non-<\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\"> DMARDs)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Ankylosing spondylitis<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Psoriatic arthritis<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults; alone or in combination with non-<\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\"> DMARDs)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Plaque psoriasis<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Juvenile idiopathic arthritis<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">Off-label<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 2 years and older; alone or in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Hidradenitis suppurativa\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Off-label\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 12 years and older)<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Uveitis\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Off-label<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (adults and children 2 years and older)<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"efficacy\">Is Remicade or Humira more effective?<\/h2>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/www.cghjournal.org\/article\/S1542-3565(13)00869-0\/fulltext\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">review of clinical studies<\/span><\/a><span style=\"font-weight: 400;\"> looked at <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> in patients with <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> and found them to be similar in terms of efficacy.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most effective medication can only be determined by your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> who can consider your medical condition(s), history, and medications you are already taking that could interact with <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">. Your provider will also consider insurance coverage as well as the route of administration (IV infusion by a <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\">, vs self-injection for <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">).\u00a0<\/span><\/p>\n<h2 id=\"insurance-coverage-cost-comparison\">Coverage and cost comparison of Remicade vs. Humira<\/h2>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> is often billed through medical insurance or Medicare Part B as a medical cost through the location where you get the infusion, such as a doctor\u2019s office, infusion center, or hospital. In some cases, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/remicade\"><span style=\"font-weight: 400;\">Remicade<\/span><\/a><span style=\"font-weight: 400;\"> may be filled at a specialty pharmacy.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/remicade-infusion-cost-with-medicare\/\"><b>How much does Medicare pay for Remicade infusions?<\/b><\/a><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/humira-cost\/\"><span style=\"font-weight: 400;\">Humira<\/span><\/a><span style=\"font-weight: 400;\"> is often filled through a specialty pharmacy, and in some cases, it can be filled at your local pharmacy. If you fill <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> at your local pharmacy, the cost could be $6,800 or more. Using a free <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/humira\"><span style=\"font-weight: 400;\">SingleCare card<\/span><\/a><span style=\"font-weight: 400;\"> can bring the price down to about $5,600 for a box of 2 prefilled syringes.\u00a0\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Remicade<\/b><b>\u00a0<\/b><\/td>\n<td><b>Humira<\/b><b>\u00a0<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">No, but may be covered under Medicare Part B\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Varies\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Varies\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 box\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typical Medicare copay<\/b><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$664-$2,960<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost<\/b><\/td>\n<td><span style=\"font-weight: 400;\">N\/A<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$5,600+<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"side-effects\">Common side effects of Remicade vs. Humira<\/h2>\n<p><span style=\"font-weight: 400;\">According to the <\/span><span style=\"font-weight: 400;\">prescribing information<\/span><span style=\"font-weight: 400;\">, the most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> are infections (upper respiratory, <\/span><span style=\"font-weight: 400;\">sinus<\/span><span style=\"font-weight: 400;\">, and throat infections), infusion-related reactions, headache, and stomach pain.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are upper respiratory infections, <\/span><span style=\"font-weight: 400;\">sinus<\/span><span style=\"font-weight: 400;\"> infections, <\/span><span style=\"font-weight: 400;\">injection site reactions<\/span><span style=\"font-weight: 400;\">, headaches, and rash.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This is not a full list of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> and other <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> may occur. Consult your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> for a full list of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">, and read the warning section below for more information on serious reactions of <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td colspan=\"2\"><b>Remicade<\/b><b>\u00a0<\/b><\/td>\n<td colspan=\"2\"><b>Humira<\/b><b>\u00a0<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Side Effect<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Frequency<\/b><\/td>\n<td><b>Applicable?<\/b><\/td>\n<td><b>Frequency<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Upper respiratory tract infection\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">32%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">17%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Nausea\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">21%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Headache\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">18%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Sinus<\/span><span style=\"font-weight: 400;\"> infection\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">14%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">11%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Stomach pain\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">7%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Sore throat\/throat infection\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">% not specified<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Cough\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No\u00a0<\/span><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Bronchitis\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">% not specified<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Rash\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">12%<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Indigestion\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">10%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No\u00a0<\/span><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Fatigue\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">9%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">No\u00a0<\/span><\/td>\n<td>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Reactions related to administration of drug<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (infusion reaction)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">20%<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (<\/span><span style=\"font-weight: 400;\">injection site reaction<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">8%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">Source: <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=a0a046c1-056d-45a9-bfd9-13b47c24f257\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">DailyMed<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=608d4f0d-b19f-46d3-749a-7159aa5f933d\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">DailyMed<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/p>\n<h2 id=\"drug-interactions\">Drug interactions of Remicade vs. Humira<\/h2>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> should not be combined with other <\/span><span style=\"font-weight: 400;\">biological<\/span><span style=\"font-weight: 400;\"> products used to treat the same conditions, due to an increase in <\/span><span style=\"font-weight: 400;\">serious infections<\/span><span style=\"font-weight: 400;\"> and other complications. Examples of interacting drugs include anakinra, abatacept, or tocilizumab.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> also can interact with drugs that have a narrow therapeutic index. This means a drug has a small window between being safe and effective, and being toxic. These drugs include Coumadin (warfarin), cyclosporine, and theophylline.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">People taking <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> should not receive <\/span><span style=\"font-weight: 400;\">live vaccines<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This is not a full list of <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\"> and other <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\"> may occur. Before taking <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">, tell your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> about all of the medications you take, including Rx and OTC drugs, vitamins, and supplements.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug<\/b><\/td>\n<td><b>Drug Class<\/b><\/td>\n<td><b>Does <\/b><b>Remicade<\/b><b> interact?<\/b><\/td>\n<td><b>Does <\/b><b>Humira<\/b><b> interact?<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Actemra (t<\/span><span style=\"font-weight: 400;\">ocilizumab)<\/span><br \/>\n<span style=\"font-weight: 400;\">Kineret<\/span><span style=\"font-weight: 400;\"> (anakinra)\u00a0<\/span><br \/>\n<span style=\"font-weight: 400;\">Orencia (abatacept)<\/span><br \/>\n<span style=\"font-weight: 400;\">Rituxan (rituximab)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Biologics<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Coumadin (warfarin)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Blood thinner\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Cyclosporine\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Immunosuppressant\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Theophylline\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Xanthine\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Live viral vaccines (such as the live MMR vaccine, live influenza nasal vaccine, live varicella vaccine) or live attenuated bacteria (such as BCG live intravesical)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Live viral vaccines or live-attenuated bacteria\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"warnings\">Warnings of Remicade and Humira<\/h2>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> have a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\">, which is the strongest warning required by the <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">. The warning states:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Because they suppress the <\/span><span style=\"font-weight: 400;\">immune system<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> can increase the risk of <\/span><span style=\"font-weight: 400;\">serious infections<\/span><span style=\"font-weight: 400;\">. These infections include tuberculosis (TB), bacterial sepsis, and invasive fungal infections, and can lead to hospitalization or death.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">If a patient develops a <\/span><span style=\"font-weight: 400;\">serious infection<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> should be stopped.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Before starting <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">, a test for TB should be performed. If the test is positive, TB treatment should begin before starting <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">. During treatment with <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">, patients should be monitored for TB and other infections.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lymphoma<\/span><span style=\"font-weight: 400;\"> and various other malignancies, some of which have been fatal, have occurred in children and adolescent patients treated with <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\"> such as <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">. Some cases of a rare type of T-cell <\/span><span style=\"font-weight: 400;\">lymphoma<\/span><span style=\"font-weight: 400;\"> called hepatosplenic T-cell <\/span><span style=\"font-weight: 400;\">lymphoma<\/span><span style=\"font-weight: 400;\"> (HSTCL) have been reported in people taking <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\">. These cases have been aggressive and caused death. Most patients who had HSTCL were also being treated with <\/span><span style=\"font-weight: 400;\">azathioprine<\/span><span style=\"font-weight: 400;\"> or mercaptopurine in addition to the <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\">. Most cases were in adolescent and young adult males with <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">ulcerative colitis<\/span><span style=\"font-weight: 400;\">.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other warnings for both <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Hepatitis B virus reactivation<\/b><span style=\"font-weight: 400;\">: <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\">, including <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">, can reactivate hepatitis B virus (HBV) in patients who are chronic carriers. In some cases, HBV reactivation in combination with <\/span><span style=\"font-weight: 400;\">TNF<\/span><span style=\"font-weight: 400;\"> treatment (and often with other immunosuppressants) has been fatal. Patients should be tested for HBV before starting <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Liver toxicity<\/b><span style=\"font-weight: 400;\">: <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\"> can cause severe liver reactions. Liver function should be monitored. Symptoms of liver problems (such as fatigue, stomach pain, yellowing of the skin, and whites of eyes) require immediate medical attention.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Heart failure<\/b><span style=\"font-weight: 400;\">: <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\"> can cause an increased risk of or worsening <\/span><span style=\"font-weight: 400;\">heart failure<\/span><span style=\"font-weight: 400;\">. The use of a <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\"> in patients with <\/span><span style=\"font-weight: 400;\">heart failure<\/span><span style=\"font-weight: 400;\"> is determined on a case-by-case basis. Patients with <\/span><span style=\"font-weight: 400;\">heart failure<\/span><span style=\"font-weight: 400;\"> should consult their <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\"> before taking <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Hypersensitivity<\/b><span style=\"font-weight: 400;\">: <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> can cause various types of severe <\/span><span style=\"font-weight: 400;\">allergic reactions<\/span><span style=\"font-weight: 400;\">. Symptoms such as hives, difficulty breathing, low blood pressure, or swelling around the face, lips, tongue, or throat, require emergency medical attention. In rare cases, <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> can cause serum sickness reactions, with symptoms like fever, rash, headache, sore throat, muscle pain, swelling, and difficulty swallowing. These symptoms require emergency medical attention.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Hematologic reactions<\/b><span style=\"font-weight: 400;\">: <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> can cause life-threatening or fatal blood problems, including low white blood cell counts, low platelet counts, and <\/span><a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/pancytopenia\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">pancytopenia<\/span><\/a><span style=\"font-weight: 400;\">. Patients should get emergency medical attention if symptoms of infection, such as fever, occur.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Neurologic reactions<\/b><span style=\"font-weight: 400;\">: <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\"> can cause central nervous system problems such as seizures, multiple scleros<\/span><span style=\"font-weight: 400;\">is, and <\/span><a href=\"https:\/\/www.cdc.gov\/campylobacter\/guillain-barre.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Guillain-Barr\u00e9 syndrome<\/span><\/a><span style=\"font-weight: 400;\">, among others. <\/span><span style=\"font-weight: 400;\">TNF blockers<\/span><span style=\"font-weight: 400;\"> should be used with caution in patients who have CNS conditions.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Live vaccines<\/b><span style=\"font-weight: 400;\">: Vaccinations should be up to date before starting treatment with a <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Live vaccines<\/span><span style=\"font-weight: 400;\"> should not be given to a patient who is taking a <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\"> because they can cause <\/span><span style=\"font-weight: 400;\">serious infections<\/span><span style=\"font-weight: 400;\">. Live attenuated bacteria, such as BCG bladder instillation to treat cancer, could also cause infection, and should not be given with a <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\">.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Additional <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> warning:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular and cerebrovascular complications during and after <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> infusion have been reported. These complications include stroke, heart attack, arrhythmia, vision loss, and changes in blood pressure. Patients should be monitored during infusion. The infusion should be stopped immediately if a reaction occurs, and emergency treatment should be initiated.<\/span><\/li>\n<\/ul>\n<h2 id=\"FAQ\">Frequently asked questions about Remicade vs. Humira<\/h2>\n<h3><span style=\"font-weight: 400;\">What is <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\">?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> is a <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\"> that is given by IV infusion. <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> contains the ingredient <\/span><span style=\"font-weight: 400;\">infliximab<\/span><span style=\"font-weight: 400;\">. It is used to treat various conditions, including <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">ulcerative colitis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">ankylosing spondylitis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">psoriatic arthritis<\/span><span style=\"font-weight: 400;\">, and <\/span><span style=\"font-weight: 400;\">plaque psoriasis<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">What is <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> is a <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\"> that is given by <\/span><span style=\"font-weight: 400;\">subcutaneous<\/span><span style=\"font-weight: 400;\"> injection (injection under the skin of the thigh or abdomen). <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> contains the ingredient <\/span><span style=\"font-weight: 400;\">adalimumab<\/span><span style=\"font-weight: 400;\">. It is used to treat conditions including <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">ulcerative colitis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">ankylosing spondylitis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">psoriatic arthritis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">plaque psoriasis<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">juvenile idiopathic arthritis<\/span><span style=\"font-weight: 400;\">, hidradenitis suppurativa, and uveitis.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Are <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> the same?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> are both <\/span><span style=\"font-weight: 400;\">biologic drugs<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">monoclonal antibodies<\/span><span style=\"font-weight: 400;\">. They both work by blocking <\/span><span style=\"font-weight: 400;\">TNF<\/span><span style=\"font-weight: 400;\"> and its inflammatory effects. However, they have several differences too, for example, in the way they are administered, and dosing. The information above outlines each drug in detail.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Renflexis (<\/span><span style=\"font-weight: 400;\">infliximab<\/span><span style=\"font-weight: 400;\">-abda), Avsola (<\/span><span style=\"font-weight: 400;\">infliximab<\/span><span style=\"font-weight: 400;\">-axxq), and Inflectra (<\/span><span style=\"font-weight: 400;\">infliximab<\/span><span style=\"font-weight: 400;\">-dyyb) are <\/span><a href=\"https:\/\/www.crohnscolitisfoundation.org\/sites\/default\/files\/2019-06\/medications-biologic-therapy.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">biosimilars<\/span><span style=\"font-weight: 400;\"> to <\/span><span style=\"font-weight: 400;\">Remicade<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other drugs in the <\/span><span style=\"font-weight: 400;\">TNF blocker<\/span><span style=\"font-weight: 400;\"> class include <\/span><span style=\"font-weight: 400;\">Enbrel<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">etanercept<\/span><span style=\"font-weight: 400;\">), <\/span><span style=\"font-weight: 400;\">Cimzia<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">certolizumab pegol<\/span><span style=\"font-weight: 400;\">), and <\/span><span style=\"font-weight: 400;\">Simponi<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">golimumab<\/span><span style=\"font-weight: 400;\">).\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Is <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> better?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> were found to be similarly effective in a review of trials in patients with <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\">. Your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> can decide if either drug is appropriate for you, taking into account your medical background, insurance coverage, and route of administration.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Can I use <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> while pregnant?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Check with your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> if you are pregnant or planning to become pregnant. Generally, <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> may or may not be given in the first and second trimester, and are not given in the third trimester of pregnancy. If you are already taking <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> and find out that you are pregnant, consult your provider right away. Babies exposed to <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> during pregnancy should not receive <\/span><span style=\"font-weight: 400;\">live vaccines<\/span><span style=\"font-weight: 400;\"> for at least six months after birth. Women who are <\/span><span style=\"font-weight: 400;\">breastfeeding<\/span><span style=\"font-weight: 400;\"> should consult their <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Can I use <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> with alcohol?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> do not interact with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/humira-and-alcohol\/\"><span style=\"font-weight: 400;\">alcohol<\/span><\/a><span style=\"font-weight: 400;\">. However, alcohol can worsen many of the conditions that <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> treat, or aggravate the <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> that they may cause. Alcohol can also interact with other medications taken for these conditions. Check with your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> regarding alcohol use.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Is <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> a <\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\">?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Yes, <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> is a <\/span><a href=\"https:\/\/www.fda.gov\/about-fda\/center-biologics-evaluation-and-research-cber\/what-are-biologics-questions-and-answers\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">biologic<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">What are the worst <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> can cause a variety of serious reactions, and some of them can be life-threatening or cause death. <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> can cause various infections, including tuberculosis. <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> may also cause <\/span><span style=\"font-weight: 400;\">lymphoma<\/span><span style=\"font-weight: 400;\"> or other malignancies. <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> can cause these serious reactions as well. Both <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\"> have many other possible <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">. Before taking <\/span><span style=\"font-weight: 400;\">Remicade<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">Humira<\/span><span style=\"font-weight: 400;\">, talk to your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> about what <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> to expect.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Drug overview &amp; main differences | Conditions treated | Efficacy | Insurance coverage and cost comparison | Side effects | Drug interactions | Warnings | FAQ Remicade and Humira are two brand-name medications used for inflammatory bowel disease (IBD, which includes Crohn\u2019s disease and ulcerative colitis) rheumatoid arthritis, and various other autoimmune diseases. You may [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":11615,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[12164,790,16414,20958],"coauthors":[10668],"class_list":["post-4191","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-arthritis","tag-chronic-disease","tag-digestive-health","tag-rheumatoid-arthritis","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Remicade vs. Humira: Differences, similarities, and which is better for you<\/title>\n<meta name=\"description\" content=\"Remicade and Humira treat a variety of autoimmune conditions, but they are not the same. 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