{"id":4323,"date":"2019-05-27T09:21:13","date_gmt":"2019-05-27T13:21:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=3561"},"modified":"2026-05-15T17:18:27","modified_gmt":"2026-05-15T21:18:27","slug":"aleve-vs-ibuprofen","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/aleve-vs-ibuprofen\/","title":{"rendered":"Aleve vs. ibuprofen: Differences, similarities, and which one is better for you?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Minor headaches, muscle aches, and fever are common ailments that can affect anyone. For many people, having the right medicine on hand can improve their peace of mind. Over-the-counter (OCT) treatment options are plentiful, with <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">nonsteroidal anti-inflammatory drugs (NSAIDs)<\/span><\/a><span style=\"font-weight: 400;\"> being some of the most commonly used medications for pain relief. You might see NSAIDs like Aleve and ibuprofen placed together in the pharmacy aisle and question which is better.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/aleve\/what-is\"><span style=\"font-weight: 400;\">Aleve<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\/what-is\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> work similarly to relieve pain and fever. As nonselective NSAIDs, Aleve and ibuprofen block the COX-1 and COX-2 enzymes, which are responsible for helping create prostaglandins or certain chemicals that play a role in inflammatory processes. The COX-2 enzyme is mainly involved with regulating pain and inflammation, while the COX-1 enzyme is involved with kidney function, platelet function, and protecting the stomach lining.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although Aleve and ibuprofen work similarly to help relieve pain and fever, they have some important differences. Continue reading to learn more about the similarities and differences between Aleve and ibuprofen and which one may be the better option.\u00a0<\/span><\/p>\n<h2 id=\"what-are-the-main-differences-between-aleve-and-ibuprofen\"><span style=\"font-weight: 400;\">What are the main differences between Aleve and ibuprofen?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Aleve and ibuprofen differ in several ways. Depending on different factors, one medication may be preferred over the other. It\u2019s always best to consult a healthcare provider when choosing the right treatment.\u00a0<\/span><\/p>\n<h3 id=\"one-is-a-brand-name-drug-and-the-other-is-a-generic\"><span style=\"font-weight: 400;\">One is a brand-name drug, and the other is a generic<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Aleve is a brand-name drug and is also available in a generic form. Ibuprofen is a generic drug that is known by various brand names, including <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/advil\"><span style=\"font-weight: 400;\">Advil<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/motrin-ib\"><span style=\"font-weight: 400;\">Motrin<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><\/a><span style=\"font-weight: 400;\">. Generic drugs are usually cheaper than their brand-name versions.\u00a0<\/span><\/p>\n<h3 id=\"they-contain-different-active-ingredients\"><span style=\"font-weight: 400;\">They contain different active ingredients<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Naproxen comes in two forms: naproxen base and naproxen sodium. Aleve contains the active ingredient naproxen sodium, the salt form of naproxen, which is more rapidly absorbed than naproxen base. Ibuprofen is the active ingredient in Advil, Motrin, and other brand-name pain relievers. Although they work similarly, naproxen and ibuprofen have different chemical structures.\u00a0<\/span><\/p>\n<h3 id=\"they-have-different-recommended-dosages\"><span style=\"font-weight: 400;\">They have different recommended dosages<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <a href=\"https:\/\/www.singlecare.com\/prescription\/aleve\/dosage\">recommended dosage of Aleve is 220 mg every eight to 12 hours<\/a>, while the <a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\/dosage\">recommended dosage of ibuprofen is 200 to 400 mg every four to six hours.<\/a> Keep in mind that these are the recommended dosages for the OTC strengths of these medications. Naproxen and ibuprofen are also available in higher prescription strengths with higher allowable dosages. In addition, Aleve and ibuprofen come in different dosage forms. Aleve is available as a tablet or liquid-filled capsule, while ibuprofen can be found as a tablet, capsule, chewable tablet, and oral liquid.\u00a0<\/span><\/p>\n<h3 id=\"the-age-limits-for-each-drug-differ\"><span style=\"font-weight: 400;\">The age limits for each drug differ<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Aleve is approved to treat fever and minor aches or pains in adults and children aged 12 years and older. Ibuprofen is approved to treat the same ailments in adults, children, and infants as young as six months old. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/children-pain-relievers-fever-reducers\/\"><span style=\"font-weight: 400;\">For young children<\/span><\/a><span style=\"font-weight: 400;\">, ibuprofen may be a better option than Aleve.<\/span><\/p>\n<h3 id=\"aleve-lasts-longer\"><span style=\"font-weight: 400;\">Aleve lasts longer<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Aleve is a long-acting NSAID that can last up to 12 hours at a time. On the other hand, ibuprofen is a short-acting NSAID that generally needs to be taken every four to six hours. If you\u2019re looking for long-term pain relief throughout the day without having to take multiple doses of a drug, Aleve may be a better option than ibuprofen.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th><span class=\"title\">Main differences between Aleve and ibuprofen<\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Aleve<\/b><\/td>\n<td><b>Ibuprofen<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Drug class<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drug (NSAID)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Nonsteroidal anti-inflammatory drug (NSAID)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Brand\/generic status<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic version available<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Brand and generic version available<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the generic name?<\/b><\/p>\n<p><b>What is the brand name?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Generic: Naproxen<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Brand: Aleve<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Generic: Ibuprofen<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Brand: Advil, Motrin, Ibu<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What form(s) does the drug come in?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Tablets<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Caplets<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Gelcaps<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Tablets<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Chewable tablets<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Oral capsules<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Oral suspension<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Liquid drops<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>What is the standard dosage?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">220 mg every 8-12 hours<\/span><\/td>\n<td><span style=\"font-weight: 400;\">200-400 mg every 4-6 hours<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>How long is the typical treatment?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">For fever: up to 3 days<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For pain: up to 10 days<\/span><\/td>\n<td><span style=\"font-weight: 400;\">For fever: up to 3 days<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For pain: up to 10 days<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Who typically uses the medication?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Adults and children aged 12 years and older<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults, children, and infants aged 6 months and older<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"conditions-treated-by-aleve-and-ibuprofen\"><span style=\"font-weight: 400;\">Conditions treated by Aleve and ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Aleve and ibuprofen are both approved to treat the following conditions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Minor aches and pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoarthritis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ankylosing spondylitis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rheumatoid arthritis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Menstrual cramps (dysmenorrhea).\u00a0<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Aleve is also approved to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/gout-treatment-and-medications\"><span style=\"font-weight: 400;\">gout<\/span><\/a><span style=\"font-weight: 400;\"> and ibuprofen is approved for the treatment of <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/migraine-definition\/\"><span style=\"font-weight: 400;\">migraines<\/span><\/a><span style=\"font-weight: 400;\">, although each can be used <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\"> for the same conditions.\u00a0<\/span><\/p>\n<h2 id=\"is-aleve-or-ibuprofen-more-effective\"><span style=\"font-weight: 400;\">Is Aleve or ibuprofen more effective?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Aleve and ibuprofen are effective pain relievers and fever reducers when compared to a placebo, or using no medication at all. Different factors can affect how well either medication works, such as dosage and the severity of the condition being treated. For example, a higher dosage of one NSAID will generally be more effective than a lower dosage of another NSAID.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although Aleve lasts longer than ibuprofen, Aleve and ibuprofen are similarly effective when taken at their recommended dosages. Research has found that naproxen and ibuprofen are similarly effective for different chronic conditions involving pain, such as osteoarthritis. According to a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15229960\/\"><span style=\"font-weight: 400;\">comparison study<\/span><\/a><span style=\"font-weight: 400;\"> that included two randomized, double-blind trials, 440 mg or 660 mg of naproxen per day was similarly effective to 1200 mg of ibuprofen per day for knee osteoarthritis. However, naproxen was found to significantly improve more symptoms of osteoarthritis than ibuprofen. In addition, patients reported better night-time pain relief with naproxen than with ibuprofen.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some people report experiencing better pain relief from one NSAID than from another. The most effective medication is the one that works best for you. Consult a healthcare provider to determine the best treatment option. Some people may find that a different NSAID product, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/meloxicam\"><span style=\"font-weight: 400;\">meloxicam<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/diclofenac-sodium\"><span style=\"font-weight: 400;\">diclofenac<\/span><\/a><span style=\"font-weight: 400;\">, may be a better choice than naproxen or ibuprofen.\u00a0<\/span><\/p>\n<h2 id=\"coverage-and-cost-comparison-of-aleve-vs-ibuprofen\"><span style=\"font-weight: 400;\">Coverage and cost comparison of Aleve vs. ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">OTC medications are not generally covered by Medicare or health insurance plans. However, the prescription-strength versions of naproxen and ibuprofen are usually covered by Medicare and insurance plans. With a SingleCare <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aleve\"><span style=\"font-weight: 400;\">Aleve<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> coupon, you could save on the cash price of OTC or prescription-strength naproxen or ibuprofen. To be able to use a discount coupon on an OTC medication, have a healthcare provider <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/prescription-savings-card-otc-meds\/\"><span style=\"font-weight: 400;\">write a prescription for it<\/span><\/a><span style=\"font-weight: 400;\"> and bring the prescription to the pharmacy.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<tbody>\n<tr class=\"header-row\">\n<td><\/td>\n<td><b>Aleve<\/b><\/td>\n<td><b>Ibuprofen<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by insurance?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes (prescription strength)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (prescription strength)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typically covered by Medicare Part D?<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Yes (prescription strength)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Yes (prescription strength)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Quantity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">20 tablets (500 mg)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">30 tablets (800 mg)<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Typical Medicare copay<\/b><\/td>\n<td><span style=\"font-weight: 400;\">$0-$20<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$0-$22<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>SingleCare cost<\/b><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/aleve\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"common-side-effects-of-aleve-vs-ibuprofen\"><span style=\"font-weight: 400;\">Common side effects of Aleve vs. ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most common potential side effects of NSAIDs like Aleve and ibuprofen include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal (GI) side effects<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Heartburn<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ringing in the ears (tinnitus)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the arms or legs (edema)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious, but less common potential side effects include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased risk of ulcers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver or kidney problems<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Of note, the risk of high blood pressure and heart problems is greater with ibuprofen than with naproxen. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or healthcare provider to learn more.<\/span><\/p>\n<h2 id=\"drug-interactions-of-aleve-vs-ibuprofen\"><span style=\"font-weight: 400;\">Drug interactions of Aleve vs. ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As NSAIDs, Aleve and ibuprofen can interact with many of the same medications. NSAIDs should be used with caution while taking the following drugs or class of drugs:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs may interact with drugs that affect clotting increasing the risk of bleeding<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Anticoagulants like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/warfarin-sodium\/what-is\"><span style=\"font-weight: 400;\">warfarin<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Antiplatelet agents like aspirin<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Certain antidepressants<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><a href=\"https:\/\/www.singlecare.com\/prescription\/prozac\/what-is\"><span style=\"font-weight: 400;\">Prozac (fluoxetine)<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Paxil (paroxetine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\/what-is\"><span style=\"font-weight: 400;\">Zoloft (sertraline)<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Effexor XR (venlafaxine)<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs may interfere with the effects of aspirin, which can cause an increased risk of heart attacks and strokes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs can counter the effects of blood pressure medications resulting in increased blood pressure\u00a0<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ace-inhibitors\"><span style=\"font-weight: 400;\">Angiotensin-converting enzyme (ACE) inhibitors<\/span><\/a>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Capoten (captopril)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Zestril (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lisinopril\/what-is\"><span style=\"font-weight: 400;\">lisinopril<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Altace (ramipril)<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/angiotensin-ii-receptor-blockers\"><span style=\"font-weight: 400;\">Angiotensin II receptor blockers (ARBs)<\/span><\/a>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Diovan (valsartan)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Cozaar (losartan)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Benicar (olmesartan)<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/beta-blockers\"><span style=\"font-weight: 400;\">Beta-blockers<\/span><\/a>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Coreg (carvedilol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Tenormin (atenolol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Zebeta (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/bisoprolol-fumarate\/what-is\"><span style=\"font-weight: 400;\">bisoprolol<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs taken with certain diuretics may lead to kidney problems<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><a href=\"https:\/\/www.singlecare.com\/prescription\/lasix\/what-is\"><span style=\"font-weight: 400;\">Lasix (furosemide)<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Microzide (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide\/what-is\"><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs may increase the risk of toxicity from Lithobid (lithium) or Rheumatrex (methotrexate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is not recommended to take Aleve with certain antacids, such as Mag-Oxide (magnesium oxide) and Amphojel (aluminum hydroxide), which can delay the absorption of Aleve into the body<\/span><\/li>\n<\/ul>\n<h2 id=\"warnings-of-aleve-and-ibuprofen\"><span style=\"font-weight: 400;\">Warnings of Aleve and ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like other NSAIDs, Aleve and ibuprofen have black box warnings on their drug labels. NSAIDs carry an increased risk of serious complications, such as cardiovascular events and gastrointestinal side effects. Using an NSAID may lead to an increased risk of blood clots, heart attacks, and strokes, as well as stomach ulcers and gastrointestinal bleeding. These adverse effects can develop with short-term or long-term use. Tell your doctor if you have a history of cardiovascular disease, such as heart disease or congestive heart failure, or gastrointestinal problems, such as stomach ulcers, before taking an NSAID. Studies suggest that naproxen has a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3676195\/\"><span style=\"font-weight: 400;\">lower risk of serious cardiovascular problems<\/span><\/a><span style=\"font-weight: 400;\"> than ibuprofen and other NSAIDs.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Avoid taking Aleve or ibuprofen if you are allergic to any ingredients in NSAIDs. Seek immediate medical attention if you experience an allergic reaction, which can cause symptoms like hives, itching, swelling of the face or throat, and trouble breathing.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Kidney problems, including kidney damage, can develop while using NSAIDs. In addition, liver damage has been reported in people taking NSAIDs. People who are on long-term treatment with NSAIDs for chronic pain should have regular checkups to monitor for problems with their kidneys or liver.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It is not recommended to take NSAIDs while pregnant due to the <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-recommends-avoiding-use-nsaids-pregnancy-20-weeks-or-later-because-they-can-result-low-amniotic\"><span style=\"font-weight: 400;\">risk of kidney problems<\/span><\/a><span style=\"font-weight: 400;\"> and other serious complications in an unborn baby. NSAIDs are generally considered safe while breastfeeding. Seek medical advice from your healthcare provider before taking an NSAID while pregnant or breastfeeding.\u00a0<\/span><\/p>\n<h2 id=\"frequently-asked-questions-about-aleve-vs-ibuprofen\"><span style=\"font-weight: 400;\">Frequently asked questions about Aleve vs. ibuprofen<\/span><\/h2>\n<h3 id=\"what-is-aleve\"><span style=\"font-weight: 400;\">What is Aleve?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Aleve is a brand-name drug that contains naproxen sodium. It is available in tablet, caplet, and gelcap form. The usual dosage is 220 mg every eight to twelve hours. Aleve is available as an over-the-counter medication and is a commonly used NSAID for fever and pain relief. The active ingredient naproxen is available in prescription strengths for more severe pain.\u00a0\u00a0<\/span><\/p>\n<h3 id=\"what-is-ibuprofen\"><span style=\"font-weight: 400;\">What is ibuprofen?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen is a generic NSAID used to treat pain and fever. It is available in brand-name and generic forms. It is also available over the counter or with a prescription. The usual dosage of OTC ibuprofen is 200 to 400 mg every four to six hours.\u00a0<\/span><\/p>\n<h3 id=\"are-aleve-and-ibuprofen-the-same\"><span style=\"font-weight: 400;\">Are Aleve and ibuprofen the same?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Both Aleve and ibuprofen are non-steroidal anti-inflammatory drugs that treat pain, inflammation, and fever. They\u2019re approved for similar uses, such as minor aches and fevers. However, they are not the same. Aleve is a brand-name drug containing naproxen sodium, while ibuprofen is a generic drug. They differ in available dosage forms, drug interactions, and risks of certain side effects.\u00a0<\/span><\/p>\n<h3 id=\"is-aleve-or-ibuprofen-better\"><span style=\"font-weight: 400;\">Is Aleve or ibuprofen better?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Aleve and ibuprofen are effective pain relief medications. They are similarly effective for treating pain and fever. However, Aleve is a longer-acting drug than ibuprofen, with effects lasting around 12 hours. Ibuprofen needs to be taken every four to six hours to provide optimal relief from pain or fever. Aleve may be a better option for long-lasting pain, while ibuprofen may be <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/children-pain-relievers-fever-reducers\/\"><span style=\"font-weight: 400;\">more suitable for younger children<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"can-i-use-aleve-or-ibuprofen-while-pregnant\"><span style=\"font-weight: 400;\">Can I use Aleve or ibuprofen while pregnant?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The FDA has advised that pregnant women at <\/span><a href=\"https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-recommends-avoiding-use-nsaids-pregnancy-20-weeks-or-later-because-they-can-result-low-amniotic\"><span style=\"font-weight: 400;\">20 weeks or later<\/span><\/a><span style=\"font-weight: 400;\"> avoid NSAIDs due to the risk of serious kidney problems. Problems with the kidney could lead to low amniotic fluid for an unborn baby, which can affect the development of the baby\u2019s lungs, muscles, and digestive system. Consult a healthcare provider about the best treatment option during pregnancy.\u00a0<\/span><\/p>\n<h3 id=\"can-i-use-aleve-or-ibuprofen-with-alcohol\"><span style=\"font-weight: 400;\">Can I use Aleve or ibuprofen with alcohol?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drinking alcohol in moderation while on Aleve or ibuprofen is not usually considered a serious problem. However, for people who are on long-term treatment with an NSAID, it\u2019s a good idea to avoid drinking alcohol. NSAID use with alcohol could lead to an increased risk of side effects, such as stomach ulcers, bleeding, kidney problems, and drowsiness.\u00a0<\/span><\/p>\n<h3 id=\"aleve-vs-ibuprofen-for-back-pain\"><span style=\"font-weight: 400;\">Aleve vs. ibuprofen for back pain<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">NSAIDs, such as naproxen and ibuprofen, can be effective medications for medical conditions such as back pain. However, you should consult a healthcare provider about the best treatment option for your back pain. You may be recommended a different option depending on the cause of the back pain. For example, low back pain caused by a herniated disc or nerve problems will not be relieved by an NSAID. NSAIDs are effective for treating pain that occurs with inflammation.\u00a0<\/span><\/p>\n<h3 id=\"which-is-better-aleve-ibuprofen-or-tylenol\"><span style=\"font-weight: 400;\">Which is better: Aleve, Ibuprofen, or Tylenol<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/is-tylenol-an-nsaid\/\"><span style=\"font-weight: 400;\">Tylenol is not an NSAID<\/span><\/a><span style=\"font-weight: 400;\">. Instead, it contains acetaminophen, which is classified as a pain reliever and fever reducer. Acetaminophen is comparable to NSAIDs for treating pain and fever, but it won\u2019t be as effective as an NSAID for treating inflammatory conditions, such as arthritis. Someone with high blood pressure, heart problems, or kidney damage may be recommended Tylenol instead of an NSAID. However, taking too much acetaminophen can lead to liver problems. It is best to talk to a healthcare professional about choosing the right OTC medication.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Minor headaches, muscle aches, and fever are common ailments that can affect anyone. For many people, having the right medicine on hand can improve their peace of mind. Over-the-counter (OCT) treatment options are plentiful, with nonsteroidal anti-inflammatory drugs (NSAIDs) being some of the most commonly used medications for pain relief. You might see NSAIDs like [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":11581,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589,8313],"tags":[10708,808],"coauthors":[8669],"class_list":["post-4323","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","category-drug-vs-drug","tag-over-the-counter-medications","tag-pain-management","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Comparing Aleve and Ibuprofen for pain, fever, and inflammation relief<\/title>\n<meta name=\"description\" content=\"Learn the differences between Aleve and ibuprofen for pain relief. 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