{"id":4579,"date":"2019-06-26T10:13:38","date_gmt":"2019-06-26T14:13:38","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=4579"},"modified":"2025-09-12T20:04:26","modified_gmt":"2025-09-13T00:04:26","slug":"xtampza-vs-oxycontin","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/xtampza-vs-oxycontin\/","title":{"rendered":"Xtampza vs. Oxycontin: Differences, similarities, and which is better for you"},"content":{"rendered":"

Drug overview & main differences<\/a> | Conditions treated<\/a> | Efficacy<\/a> | Insurance coverage and cost comparison<\/a> | Side effects<\/a> | Drug interactions<\/a> | Warnings<\/a> | FAQ<\/a><\/p>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> are brand-name drugs used to treat <\/span>severe pain<\/span> that is not relieved by non-<\/span>opioid<\/span> treatment options<\/span>. Both drugs are <\/span>extended-release<\/span> formulations<\/span> of the <\/span>opioid analgesic<\/span>, <\/span>oxycodone<\/span>. <\/span>Opioid <\/span>analgesics<\/span><\/a> work by binding to <\/span>opioid<\/span> receptors<\/span> in the <\/span>central nervous system<\/span> to block the sensation of pain.\u00a0<\/span><\/p>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> are <\/span>Schedule II<\/span> controlled substances that carry a risk of abuse and dependence. They should only be used as prescribed by a <\/span>healthcare provider<\/span>.\u00a0<\/span><\/p>\n

Continue reading to learn about the similarities and differences between <\/span>Xtampza ER<\/span> and <\/span>Oxycontin<\/span>.<\/span><\/p>\n

What are the main differences between Xtampza ER vs. Oxycontin<\/h2>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> both contain <\/span>extended-release oxycodone<\/span>. However, they differ in how they are formulated.\u00a0<\/span><\/p>\n

Xtampza ER<\/span><\/a> is manufactured by <\/span>Collegium Pharmaceutical, Inc<\/span>. and comes in an <\/span>abuse-deterrent formulation<\/span>. Xtampza <\/span>extended-release<\/span> capsules contain <\/span>microspheres<\/span> with inactive ingredients to prevent abuse, misuse, and <\/span>tampering<\/span> of the drug.\u00a0<\/span><\/p>\n

Xtampza ER<\/span> is approved for use in adults. It is usually prescribed to be taken every 12 hours with food. The drug is best absorbed into the body when taken with food.\u00a0<\/span><\/p>\n

Oxycontin<\/span><\/a> is manufactured by <\/span>Purdue Pharma<\/span> L.P. It is available as an <\/span>extended-release tablet<\/span> that is usually prescribed to be taken every 12 hours with or without food. The absorption of the drug is not affected by food.\u00a0<\/span><\/p>\n

Oxycontin<\/span> is approved for use in adults and children aged 11 years and older who have already been taking a minimum daily <\/span>opioid<\/span> dose of 20 mg of <\/span>oxycodone<\/span>.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
Main differences between Xtampza ER vs. Oxycontin<\/span><\/th>\n<\/tr>\n<\/thead>\n
<\/td>\nXtampza ER<\/b><\/td>\nOxycontin<\/b><\/td>\n<\/tr>\n
Drug class<\/b><\/td>\nOpioid analgesic<\/span><\/td>\nOpioid analgesic<\/span><\/td>\n<\/tr>\n
Brand\/generic status<\/b><\/td>\nOnly available as a brand-name medication<\/span><\/td>\nBrand and generic version available<\/span><\/td>\n<\/tr>\n
What is the generic name?<\/b><\/td>\nOxycodone<\/span> base, <\/span>extended-release<\/span><\/td>\nOxycodone<\/span> hydrochloride<\/span>, <\/span>extended-release<\/span><\/td>\n<\/tr>\n
What form(s) does the drug come in?<\/b><\/td>\nExtended-release<\/span> oral capsule<\/span><\/td>\nExtended-release<\/span> oral tablet<\/span><\/td>\n<\/tr>\n
What is the standard dosage?<\/b><\/td>\nOne 9 mg oral capsule every 12 hours with food<\/span>
\nDosage may be adjusted based on response to treatment. The lowest effective dose should be used.\u00a0<\/span><\/td>\n		One 10 mg oral tablet every 12 hours<\/span>
\nDosage may be adjusted based on response to treatment. The lowest effective dose should be used.\u00a0<\/span><\/td>\n<\/tr>\n
How long is the typical treatment?<\/b><\/td>\nShort-term<\/span><\/td>\nShort-term<\/span><\/td>\n<\/tr>\n
Who typically uses the medication?<\/b><\/td>\nAdults<\/span><\/td>\nAdults and children aged 11 years or older<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Conditions treated by Xtampza ER and Oxycontin<\/h2>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> are <\/span>FDA<\/span>-approved <\/span>opioid medications<\/span> that treat moderate to <\/span>severe pain<\/span>. They are generally reserved for treating <\/span>chronic pain<\/span><\/a> that is not relieved by non-<\/span>opioid analgesics<\/span>. <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> may be prescribed after non-<\/span>opioid analgesics<\/span> like <\/span>acetaminophen<\/span> or nonsteroidal anti-inflammatory drugs (NSAIDs) have failed to provide adequate <\/span>pain relief<\/span>. <\/span>Extended-release opioids<\/span>, like <\/span>Xtampza ER<\/span> and <\/span>Oxycontin<\/span>, may also be prescribed after an <\/span>immediate-release opioid<\/span> has been tried.\u00a0<\/span><\/p>\n\n\n\n\n
Condition<\/b><\/td>\nXtampza ER<\/b><\/td>\nOxycontin<\/b><\/td>\n<\/tr>\n
Management of pain severe enough to require an <\/span>opioid analgesic<\/span> and for which alternative treatments are inadequate<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Is Xtampza ER or Oxycontin more effective?<\/h2>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> both contain <\/span>extended-release oxycodone<\/span> and are similarly effective for <\/span>pain management<\/span>. Their primary difference lies in their potential to be abused.\u00a0<\/span><\/p>\n

People who are susceptible to <\/span>drug abuse<\/span> may crush and snort <\/span>opioid<\/span> prescription drugs<\/span> like <\/span>Oxycontin<\/span>. Crushing <\/span>extended-release oxycodone<\/span> tablets can impair the drug\u2019s <\/span>pharmacokinetics<\/span>, or the delivery and absorption of the drug into the body. Crushed <\/span>Oxycontin<\/span> tablets are rapidly absorbed into the body, increasing the risk of overdose and abuse.\u00a0<\/span><\/p>\n

Randomized <\/span>clinical trials<\/span> have shown that crushing <\/span>Xtampza ER capsules<\/span> does not affect its <\/span>extended-release<\/span> properties. Compared to crushed <\/span>Oxycontin<\/span> tablets, crushed <\/span>Xtampza ER capsules<\/span> result in <\/span>lower <\/span>plasma concentrations<\/span><\/a> of the <\/span>opioid<\/span>. <\/span>Xtampza ER capsules<\/span> have been shown to be similarly effective to other <\/span>opioids<\/span>, and they are associated with <\/span>lower rates of abuse<\/span><\/a>.<\/span><\/p>\n

The most effective <\/span>opioid<\/span> prescription drug<\/span> will depend on a person\u2019s overall condition. Consult with a <\/span>healthcare provider<\/span> for the most effective <\/span>treatment option<\/span>.\u00a0<\/span><\/p>\n

Coverage and cost comparison of Xtampza ER vs. Oxycontin<\/h2>\n

Xtampza ER capsules<\/span> may be covered by some Medicare and insurance plans. Many insurance plans may prefer to provide coverage for <\/span>Xtampza ER<\/span> over <\/span>Oxycontin<\/span> due to its <\/span>abuse-deterrent<\/span> properties. <\/span>Xtampza ER<\/span>, however, may be more expensive than <\/span>Oxycontin<\/span> with an average cash price of $424.31 versus $118.13 with <\/span>Oxycontin<\/span>.\u00a0<\/span><\/p>\n

A SingleCare discount card may help reduce the cash price of <\/span>Xtampza ER<\/span><\/a> or <\/span>Oxycontin<\/span><\/a>. Consult with an insurance provider or pharmacist to determine the exact costs and to compare savings options.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n
<\/td>\nXtampza ER<\/b><\/td>\nOxycontin<\/b><\/td>\n<\/tr>\n
Typically covered by insurance?<\/b><\/td>\nMaybe<\/span><\/td>\nMaybe<\/span><\/td>\n<\/tr>\n
Typically covered by Medicare Part D?<\/b><\/td>\nMaybe<\/span><\/td>\nNo<\/span><\/td>\n<\/tr>\n
Quantity<\/b><\/td>\n60, 9 mg oral capsules<\/span><\/td>\n60, 10 mg oral tablets<\/span><\/td>\n<\/tr>\n
Typical Medicare copay<\/b><\/td>\nVaries<\/span><\/td>\nVaries<\/span><\/td>\n<\/tr>\n
SingleCare cost<\/b><\/td>\n$300+<\/span><\/td>\n$81+<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Common side effects of Xtampza ER vs. Oxycontin<\/h2>\n

In <\/span>clinical trials<\/span>, the most common <\/span>side effects<\/span> of <\/span>Xtampza ER<\/span> were nausea, headache, <\/span>constipation<\/span>, <\/span>drowsiness<\/span>, itching, vomiting, and dizziness.\u00a0<\/span>
\nIn <\/span>clinical trials<\/span>, the most common <\/span>side effects<\/span> of <\/span>Oxycontin<\/span> were <\/span>constipation<\/span>, nausea, <\/span>drowsiness<\/span>, dizziness, vomiting, itching, headache, dry mouth, weakness, and sweating.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
<\/td>\nXtampza ER<\/b><\/td>\nOxycontin<\/b><\/td>\n<\/tr>\n
Side Effect<\/b><\/td>\nApplicable?<\/b><\/td>\nFrequency<\/b><\/td>\nApplicable?<\/b><\/td>\nFrequency<\/b><\/td>\n<\/tr>\n
Nausea<\/span><\/td>\nYes<\/span><\/td>\n17%<\/span><\/td>\nYes<\/span><\/td>\n23%<\/span><\/td>\n<\/tr>\n
Headache<\/span><\/td>\nYes<\/span><\/td>\n14%<\/span><\/td>\nYes<\/span><\/td>\n7%<\/span><\/td>\n<\/tr>\n
Constipation<\/span><\/td>\nYes<\/span><\/td>\n13%<\/span><\/td>\nYes<\/span><\/td>\n23%<\/span><\/td>\n<\/tr>\n
Drowsiness<\/span><\/td>\nYes<\/span><\/td>\n9%<\/span><\/td>\nYes<\/span><\/td>\n23%<\/span><\/td>\n<\/tr>\n
Itching<\/span><\/td>\nYes<\/span><\/td>\n7%<\/span><\/td>\nYes<\/span><\/td>\n13%<\/span><\/td>\n<\/tr>\n
Vomiting<\/span><\/td>\nYes<\/span><\/td>\n6%<\/span><\/td>\nYes<\/span><\/td>\n12%<\/span><\/td>\n<\/tr>\n
Dizziness<\/span><\/td>\nYes<\/span><\/td>\n6%<\/span><\/td>\nYes<\/span><\/td>\n13%<\/span><\/td>\n<\/tr>\n
Weakness<\/span><\/td>\nNo<\/span><\/td>\n–<\/span><\/td>\nYes<\/span><\/td>\n5%<\/span><\/td>\n<\/tr>\n
Sweating<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\nYes<\/span><\/td>\n5%<\/span><\/td>\n<\/tr>\n
Diarrhea<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\n<\/tr>\n
Decreased appetite<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\n<\/tr>\n
Insomnia<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\n<\/tr>\n
Abdominal pain<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\nYes<\/span><\/td>\n1\u20135%<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Frequency is not based on data from a head-to-head trial. This may not be a complete list of adverse effects that can occur. Please refer to your doctor or <\/span><\/i>healthcare provider<\/span><\/i> to learn more.<\/span><\/i><\/p>\n

Source: DailyMed (<\/span>Xtampza ER<\/span><\/a>), DailyMed (<\/span>Oxycontin<\/span><\/a>)<\/span><\/p>\n

Drug interactions of Xtampza ER vs. Oxycontin<\/h2>\n

Oxycodone<\/span> is primarily processed in the liver by certain enzymes called CYP3A4 and CYP2D6. Drugs that block these enzymes are called <\/span>inhibitors<\/span> while drugs that increase the activity of these enzymes are called inducers.\u00a0<\/span><\/p>\n

Combining <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> with CYP3A4 or CYP2D6 <\/span>inhibitors<\/span> can lead to increased blood levels of <\/span>oxycodone<\/span>, which can lead to increased <\/span>side effects<\/span> of <\/span>oxycodone<\/span>. Examples of CYP <\/span>inhibitors<\/span> include <\/span>macrolide antibiotics<\/span><\/a>, azole <\/span>antifungal agents<\/span><\/a>, and <\/span>protease <\/span>inhibitors<\/span><\/a>.\u00a0<\/span><\/p>\n

CYP3A4 inducers<\/span> can speed up the metabolism of <\/span>oxycodone<\/span>, decreasing the pain-relieving effects of the <\/span>opioid<\/span>. Drugs that act as <\/span>CYP3A4 inducers<\/span> include carbamazepine and <\/span>phenytoin<\/span>.\u00a0<\/span><\/p>\n

The use of <\/span>benzodiazepines<\/span><\/a>, <\/span>muscle relaxants<\/span>, and other <\/span>CNS depressants<\/span> should be avoided or monitored while taking an <\/span>opioid medication<\/span>. Combining these drugs may lead to an increased risk of respiratory depression, <\/span>sedation<\/span>, coma, or death.\u00a0<\/span><\/p>\n

Combining an <\/span>opioid medication<\/span> with drugs that increase serotonin levels can increase the risk of serotonin syndrome. The use of <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> should be monitored while taking drugs like <\/span>SSRIs<\/span><\/a>, <\/span>SNRIs<\/span><\/a>, <\/span>tricyclic antidepressants<\/span><\/a>, <\/span>triptans<\/span><\/a>, and <\/span>MAOIs<\/span><\/a>. The use of <\/span>Xtampza ER<\/span> and <\/span>Oxycontin<\/span> is not recommended for people taking MAOIs or within 14 days of stopping an MAOI.\u00a0<\/span><\/p>\n

Opioids<\/span> may reduce the effectiveness of <\/span>diuretics<\/span><\/a>. <\/span>Blood pressure<\/span> may need to be monitored in people taking an <\/span>opioid<\/span> and a diuretic.\u00a0<\/span><\/p>\n

Other <\/span>drug interactions<\/span> are listed below.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Drug<\/b><\/td>\nDrug Class<\/b><\/td>\nXtampza ER<\/b><\/td>\nOxycontin<\/b><\/td>\n<\/tr>\n
Erythrocin (erythromycin\u00a0<\/span>
\nBiaxin (clarithromycin)<\/span><\/td>\n		Macrolide antibiotics<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Diflucan (fluconazole)\u00a0<\/span>
\nNizoral (ketoconazole)<\/span><\/td>\n		Azole antifungal agents<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Norvir (ritonavir)<\/span><\/td>\nProtease <\/span>inhibitors<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Tegretol (carbamazepine)<\/span>
\nDilantin (<\/span>phenytoin<\/span>)<\/span><\/td>\n		Anticonvulsants<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Xanax\u00a0<\/span>
\n(alprazolam)\u00a0<\/span>
\nValium\u00a0<\/span>
\n(diazepam)\u00a0<\/span>
\nAtivan\u00a0<\/span>
\n(lorazepam)\u00a0<\/span>
\nKlonopin (clonazepam)<\/span><\/td>\n		Benzodiazepines<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Risperdal (risperidone)<\/span>
\nSeroquel (quetiapine)<\/span>
\nZyprexa (olanzapine)<\/span><\/td>\n		Antipsychotics<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Methadone<\/span>\u00a0<\/span>
\nCodeine<\/span>
\nDuragesic\u00a0<\/span>
\n(<\/span>fentanyl<\/span><\/a>)\u00a0<\/span>
\nMorphine\u00a0<\/span><\/td>\n		Opioids<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Alcohol<\/span><\/td>\nAlcohol<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Prozac\u00a0<\/span>
\n(fluoxetine)\u00a0<\/span>
\nPaxil\u00a0<\/span>
\n(paroxetine)\u00a0<\/span>
\nZoloft\u00a0<\/span>
\n(sertraline)\u00a0<\/span>
\nCelexa\u00a0<\/span>
\n(citalopram)\u00a0<\/span>
\nLexapro (escitalopram)<\/span><\/td>\n		Selective serotonin reuptake <\/span>inhibitors<\/span> (SSRIs)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Cymbalta (duloxetine)<\/span>
\nEffexor\u00a0<\/span>
\n(venlafaxine)\u00a0<\/span>
\nPristiq (desvenlafaxine)<\/span><\/td>\n		Serotonin and norepinephrine reuptake <\/span>inhibitors<\/span> (SNRIs)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Pamelor (nortriptyline)\u00a0<\/span>
\nElavil\u00a0<\/span>
\n(amitriptyline)<\/span><\/td>\n		Tricyclic antidepressants (TCAs)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Imitrex (sumatriptan)\u00a0<\/span>
\nMaxalt\u00a0<\/span>
\n(rizatriptan)<\/span><\/td>\n		Triptans<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Flexeril (cyclobenzaprine)\u00a0<\/span>
\nSkelaxin (metaxalone)<\/span><\/td>\n		Muscle relaxants<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Azilect\u00a0<\/span>
\n(rasagiline)<\/span>
\nEldepryl\u00a0<\/span>
\n(selegiline)\u00a0<\/span>
\nParnate (tranylcypromine)<\/span><\/td>\n		Monoamine oxidase <\/span>inhibitors<\/span> (MAOIs)<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Hydrochlorothiazide\u00a0<\/span>
\nLasix (furosemide)<\/span><\/td>\n		Diuretics<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n
Cogentin (benztropine)\u00a0<\/span>
\nBenadryl (diphenhydramine)<\/span>
\nDitropan (oxybutynin)\u00a0<\/span>
\nDetrol (tolterodine)<\/span><\/td>\n		Anticholinergic drugs<\/span><\/td>\nYes<\/span><\/td>\nYes<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

This may not be a complete list of all possible <\/span><\/i>drug interactions<\/span><\/i>. Consult a <\/span><\/i>healthcare provider<\/span><\/i> with all medications you may be taking.\u00a0<\/span><\/i><\/p>\n

Warnings of Xtampza ER and Oxycontin<\/h2>\n

Medications containing an <\/span>opioid<\/span>, like <\/span>oxycodone<\/span>, carry a risk of abuse, misuse, and addiction, which can lead to overdose and death. An overdose of these medications may cause <\/span>fatal respiratory depression<\/span> and <\/span>sedation<\/span>. The risk of serious adverse events may be increased when combining <\/span>opioids<\/span> with <\/span>benzodiazepines<\/span> or other <\/span>CNS depressants<\/span>. <\/span>Opioid medications<\/span> should only be used as prescribed by a <\/span>healthcare provider<\/span>.\u00a0<\/span><\/p>\n

Opioid medications<\/span><\/a> should not be discontinued abruptly. The abrupt discontinuation of an <\/span>opioid medication<\/span> in people who are dependent on the drug may lead to severe <\/span>withdrawal symptoms<\/span>, uncontrolled pain, or suicide. <\/span>Withdrawal symptoms<\/span> may include muscle pain, insomnia, irritability, increased <\/span>blood pressure<\/span>, and nausea.\u00a0<\/span><\/p>\n

The <\/span>ingestion<\/span> of <\/span>opiates<\/span> in women who are pregnant can cause harm to an unborn baby. <\/span>Breastfeeding<\/span> while taking an <\/span>opioid medication<\/span> can cause harm to a breastfed infant. <\/span>Xtampza ER<\/span> and <\/span>Oxycontin<\/span> should be avoided in women who are pregnant or <\/span>breastfeeding<\/span>.\u00a0<\/span><\/p>\n

Consult with a <\/span>healthcare provider<\/span> or the <\/span>prescribing information<\/span> for other possible warnings and precautions associated with <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span>.\u00a0<\/span><\/p>\n

Frequently asked questions about Xtampza ER vs. Oxycontin<\/h2>\n

What is <\/span>Xtampza ER<\/span>?<\/span><\/h3>\n

Xtampza ER<\/span> is a <\/span>prescription opioid analgesic<\/span> used to treat pain. It is available as an <\/span>extended-release<\/span> capsule that is formulated to prevent <\/span>drug abuse<\/span> and misuse. <\/span>Xtampza ER capsules<\/span> come in strengths of 9 mg, 13.5 mg, 18 mg, 27 mg, and 36 mg. It is usually prescribed to be taken every 12 hours.\u00a0<\/span><\/p>\n

What is <\/span>Oxycontin<\/span>?<\/span><\/h3>\n

Oxycontin<\/span> is a <\/span>prescription opioid medication<\/span> used to treat pain. It is available as an <\/span>extended-release tablet<\/span> that can be taken every 12 hours to relieve pain. <\/span>Oxycontin<\/span> extended-release tablets<\/span> are available in strengths of 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg, and 80 mg.<\/span><\/p>\n

Are <\/span>Xtampza ER<\/span> and <\/span>Oxycontin<\/span> the same?<\/span><\/h3>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> are two <\/span>extended-release oxycodone formulations<\/span>. <\/span>Xtampza ER<\/span> comes as an <\/span>extended-release<\/span> capsule while <\/span>Oxycontin<\/span> comes as an <\/span>extended-release tablet<\/span>. Both drugs are usually prescribed to be taken every 12 hours for <\/span>chronic pain relief<\/span>. They are typically only recommended after non-<\/span>opioid<\/span> alternatives have been tried without adequate <\/span>pain relief<\/span>.\u00a0<\/span><\/p>\n

Is <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> better?<\/span><\/h3>\n

Xtampza ER<\/span> and <\/span>Oxycontin<\/span> are similarly effective <\/span>opioid<\/span> pain medications<\/span> that contain <\/span>oxycodone<\/span>. They both provide <\/span>pain relief<\/span> in people experiencing moderate to <\/span>severe pain<\/span> associated with <\/span>chronic back pain<\/span><\/a> or other conditions. However, <\/span>Xtampza ER<\/span> is resistant to <\/span>tampering<\/span> and has a lower risk of abuse and misuse than <\/span>Oxycontin<\/span>. One possible downside to <\/span>Xtampza ER<\/span> is that it needs to be taken with food for maximum effects.\u00a0<\/span><\/p>\n

Can I use <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> while pregnant?<\/span><\/h3>\n

Opioid<\/span> prescription drugs<\/span> should not be taken while pregnant. Taking an <\/span>opioid medication<\/span> while pregnant may cause harm to an unborn baby. The use of <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> while pregnant can cause <\/span>neonatal <\/span>opioid<\/span> withdrawal syndrome<\/span><\/a>, which may be life-threatening.\u00a0<\/span><\/p>\n

Can I use <\/span>Xtampza ER<\/span> or <\/span>Oxycontin<\/span> with alcohol?<\/span><\/h3>\n

It is recommended to avoid alcohol with <\/span>opioid use<\/span>. Both alcohol and <\/span>opioid medications<\/span> have <\/span>CNS depressant<\/span> effects. Drinking alcohol with <\/span>opioids<\/span> can increase the risk of profound <\/span>sedation<\/span>, respiratory depression, coma, and death.\u00a0<\/span><\/p>\n

Does <\/span>Xtampza ER<\/span> work for pain?<\/span><\/h3>\n

Xtampza ER<\/span> is an effective <\/span>extended-release opioid<\/span> for <\/span>pain relief<\/span>. It may be prescribed if other non-<\/span>opioid analgesics<\/span> are unable to provide adequate <\/span>pain relief<\/span>. <\/span>Clinical trials<\/span><\/a> have shown that <\/span>Xtampza ER<\/span> is an effective medication to relieve pain in people with chronic lower back pain. It may also be prescribed for pain associated with other medical conditions, including cancer.\u00a0<\/span><\/p>\n

How long does it take <\/span>Xtampza ER<\/span> to get into your system?<\/span><\/h3>\n

Xtampza ER<\/span> can take around 4.5 hours to reach peak levels in the blood. Compared to <\/span>immediate-release oxycodone<\/span>, <\/span>Xtampza ER<\/span> takes about three hours longer to reach peak levels in the blood. <\/span>Xtampza ER<\/span> must be taken with food for maximum absorption.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Drug overview & main differences | Conditions treated | Efficacy | Insurance coverage and cost comparison | Side effects | Drug interactions | Warnings | FAQ Xtampza ER and Oxycontin are brand-name drugs used to treat severe pain that is not relieved by non-opioid treatment options. Both drugs are extended-release formulations of the opioid analgesic, […]<\/p>\n","protected":false},"author":15,"featured_media":12316,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[8313],"tags":[808,4350],"coauthors":[8669],"class_list":["post-4579","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-vs-drug","tag-pain-management","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"\nXtampza vs. Oxycontin: Differences, similarities, and which is better for you<\/title>\n<meta name=\"description\" content=\"Xtampza and Oxycontin treat severe pain but they work in different ways. 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