{"id":45821,"date":"2021-11-04T09:21:17","date_gmt":"2021-11-04T13:21:17","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=45821"},"modified":"2026-03-23T11:24:44","modified_gmt":"2026-03-23T15:24:44","slug":"muse-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/muse-side-effects\/","title":{"rendered":"Muse side effects and how to avoid them"},"content":{"rendered":"<p><a href=\"#common-side-effects\">Muse side effects<\/a> | <a href=\"#serious-side-effects\">Serious side effects<\/a> | <a href=\"#penile-pain\">Penile pain<\/a> |<br \/>\n<a href=\"#low-blood-pressure\">Low blood pressure<\/a> | <a href=\"#priapism\">Priapism<\/a> | <a href=\"#how-long-do-side-effects-last\">How long do side effects last?<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a> | <a href=\"#resources\">Resources<\/a><\/p>\n<p><span style=\"font-weight: 400;\">Muse is a prescription brand-name drug used for the treatment of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/erectile-dysfunction-treatment-and-medications\"><span style=\"font-weight: 400;\">erectile dysfunction<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/alprostadil\"><span style=\"font-weight: 400;\">Alprostadil<\/span><\/a><span style=\"font-weight: 400;\">, the active ingredient in Muse, widens arteries in the penis to allow more blood flow into erectile tissues to allow for successful sexual intercourse. Muse is administered as a transurethral suppository about 10 minutes before anticipated sexual activity as needed. The suppository is inserted into the urethra with an applicator and the medicine is absorbed into penile tissues through the urethra.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As with all prescription drugs, Muse may not be right for everyone. Side effects are common, particularly relating to problems associated with urethral insertion. Some men may not be able to take the drug because of pre-existing physical or medical issues. However, there are ways to minimize or manage problems when taking Muse.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">RELATED: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/muse\"><span style=\"font-weight: 400;\">Get Muse discounts<\/span><\/a><\/p>\n<h2 id=\"common-side-effects\">Common side effects of Muse<\/h2>\n<p><span style=\"font-weight: 400;\">Muse is administered as a urethral suppository, that is, it is inserted into the urethra opening at the end of the penis. The most common side effects of Muse are related to this method of administration, such as penile, urethral burning, and minor urethral bleeding. Because the drug is rapidly eliminated in the body, system-wide side effects are less common.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/184005\/Muse\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Muse are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Penile pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urethral burning<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Minor urethral bleeding<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Testicular pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flu-like symptoms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pelvic pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure (hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the leg veins<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rapid pulse<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Because the drug is administered into the urethra, a female partner might also experience side effects. In clinical trials, approximately <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4c55f3f9-c4cf-11df-851a-0800200c9a66\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">5.8%<\/span><\/a><span style=\"font-weight: 400;\"> of female sexual partners reported vaginal burning or itching.<\/span><\/p>\n<h2 id=\"serious-side-effects\">Serious side effects of Muse<\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/184005\/Muse\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">serious side effects<\/span><\/a><span style=\"font-weight: 400;\"> of alprostadil include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prolonged erections (4 or more hours)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Painful erections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Curving of the penis with painful erection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fainting (syncope)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling in the testes<\/span><\/li>\n<\/ul>\n<h3 id=\"penile-pain\">Muse and penile pain<\/h3>\n<p><span style=\"font-weight: 400;\">Because Muse suppositories are inserted directly into the urethra, many men taking Muse will experience pain or discomfort during or after insertion. Penile pain is the most common, reported by <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4c55f3f9-c4cf-11df-851a-0800200c9a66\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">32%<\/span><\/a><span style=\"font-weight: 400;\"> of men in clinical trials. Burning in the urethra was reported by 12% of the patients, testicular pain in 5%, and minor bleeding from the urethra from another 5%. Self-injected alprostadil (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/caverject-impulse\"><span style=\"font-weight: 400;\">Caverject Impulse<\/span><\/a><span style=\"font-weight: 400;\">) also has a high incidence of penis pain\u2014in <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4dec1dbd-c63b-4a1b-81cb-c8d29696cc40\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">37%<\/span><\/a><span style=\"font-weight: 400;\"> of men during clinical trials\u2014but can also cause bruising at the injection site in 3% of men. For both Muse and Caverject, these side effects can be discouraging enough to persuade men to discontinue alprostadil treatment for ED. Healthcare providers usually turn to alprostadil treatments only when first-line ED treatment with oral <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/viagra\"><span style=\"font-weight: 400;\">Viagra<\/span><\/a><span style=\"font-weight: 400;\"> (sildenafil) or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cialis\"><span style=\"font-weight: 400;\">Cialis<\/span><\/a><span style=\"font-weight: 400;\"> (vardenafil) is not possible or doesn\u2019t work.<\/span><\/p>\n<h3 id=\"low-blood-pressure\">Muse and low blood pressure<\/h3>\n<p><span style=\"font-weight: 400;\">Alprostadil can cause blood pressure problems including <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-blood-pressure\/\"><span style=\"font-weight: 400;\">low blood pressure<\/span><\/a><span style=\"font-weight: 400;\">, high blood pressure, and flushing. In clinical trials, approximately <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4c55f3f9-c4cf-11df-851a-0800200c9a66\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">3%<\/span><\/a><span style=\"font-weight: 400;\"> of men taking Muse experienced clinically significant low blood pressure, or hypotension. About 0.4% of men fainted within one hour of administering a Muse suppository. Men taking Muse should watch carefully for signs of low blood pressure after putting in a suppository: dizziness, lightheadedness, and feeling faint. If Muse is causing low blood pressure or fainting, tell the prescribing healthcare provider. Doses may need to be reduced.\u00a0<\/span><\/p>\n<h3 id=\"priapism\">Muse and priapism<\/h3>\n<p><span style=\"font-weight: 400;\">All ED medications carry a risk for prolonged erections, defined as an erection that lasts longer than four hours. Prolonged and painful erections that last for longer than six hours are a serious medical condition called priapism. Untreated, priapism can do permanent damage to the erectile tissues in the penis. Both prolonged erections and priapism should receive immediate medical attention.\u00a0<\/span><\/p>\n<h2 id=\"how-long-do-side-effects-last\">How long do side effects last?<\/h2>\n<p><span style=\"font-weight: 400;\">After a Muse dose is administered and absorbed through the urethra, the alprostadil in the dose is rapidly metabolized by enzymes in the urethra and corpus cavernosum. The metabolites are then cleared by the kidneys and liver. With a half-life of <\/span><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/5280723#section=Metabolism-Metabolites\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">five to 10 minutes<\/span><\/a><span style=\"font-weight: 400;\">, the drug\u2019s effects on erections last about 50 to 60 minutes. Most side effects including blood pressure effects, penis pain, testes pain, dizziness, fainting, and headache should clear up by then.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">By definition, prolonged erections and priapism last for several hours, but these effects are rare (less than 1%) in people taking Muse. Prolonged erections could, however, permanently worsen erectile dysfunction.\u00a0<\/span><\/p>\n<h2 id=\"warnings\">Muse contraindications &amp; warnings<\/h2>\n<p><span style=\"font-weight: 400;\">Muse is more likely to cause problems in some people than others. Below we discuss restrictions and interactions in more detail.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The U.S. Food and Drug Administration (FDA) does not consider alprostadil to have a potential for abuse or physical dependence.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Although no Muse overdose has been reported, an overdose of Muse could increase the risk of low blood pressure, penis pain, or prolonged erection or priapism. If too much Muse has been administered, contact a poison helpline or get medical help.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Restrictions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Because of potential hazards, Muse can never be prescribed <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4c55f3f9-c4cf-11df-851a-0800200c9a66\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">to people with<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><b><\/b><\/p>\n<ul>\n<li aria-level=\"1\"><b>Allergies to Muse: <\/b><span style=\"font-weight: 400;\">Anyone with a history of hypersensitivity to alprostadil or the other ingredients in Muse cannot safely take this medicine.<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Penile abnormalities: <\/b><span style=\"font-weight: 400;\">Alprostadil can worsen penile abnormalities including narrow urethra (urethral strictures), abnormal curvature, penile fibrosis, Peyronie\u2019s disease, abnormal location of the urethral opening (hypospadias), swelling of the glans area at the top of the penis (balanitis), acute or chronic swelling of the urethra (urethritis).\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Penile Implants: <\/b><span style=\"font-weight: 400;\">Muse has not been studied in patients with penile implants. A potential for drug-device interaction exists.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Sickle-cell anemia, thrombocythemia, polycythemia, leukemia, or multiple myeloma: <\/b><span style=\"font-weight: 400;\">All of these conditions either make it difficult for blood to flow through blood vessels (hyperviscosity syndrome) or raise the risk for blood clots; both problems make people taking Muse more likely to experience prolonged erections or priapism.<\/span><\/li>\n<li aria-level=\"1\"><b>Heart disease: <\/b><span style=\"font-weight: 400;\">Sexual activity is considered a vigorous physical exercise that increases heart rate. Some men cannot safely engage in sexual activity because of this added strain to the heart. If the risks from sexual activity are too great, they cannot get a prescription for Muse or any other ED medication.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Patients should avoid activities such as driving or hazardous tasks where injury could result if dizziness or syncope were to occur after the administration of Muse.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Men with low blood pressure can take Muse but may need to be given a lower dose. People with bleeding disorders may be at risk of prolonged bleeding from inserting the urethral suppository, so extra caution is required when using the Muse urethral applicator.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Pregnancy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Although Muse is never prescribed to women, men who are using Muse must use a condom <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4c55f3f9-c4cf-11df-851a-0800200c9a66\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">when having sex with a pregnant woman<\/span><\/a><span style=\"font-weight: 400;\">. In men taking Muse, alprostadil can be found in their ejaculate. As a prostaglandin, a common protein found in the body, alprostadil has many effects. Among those effects, prostaglandins <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Muse-alprostadil-1645\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">can induce uterine contractions and labor<\/span><\/a><span style=\"font-weight: 400;\">. Therefore, Must <\/span><i><span style=\"font-weight: 400;\">should not be used<\/span><\/i><span style=\"font-weight: 400;\"> for sexual intercourse with a partner who is pregnant unless a condom barrier is used.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The FDA has not approved Muse for use in children.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People older than 65 can take Muse in the same doses as younger adults. However, seniors are more at risk for serious cardiovascular events brought on by vigorous activity such as sexual intercourse. All patients young and old prescribed erectile dysfunction medications will need a thorough evaluation of their heart health.\u00a0<\/span><\/p>\n<h2 id=\"interactions\">Muse interactions<\/h2>\n<p><span style=\"font-weight: 400;\">Alprostadil is a short-lived drug, lasting only an hour or so in the body. Drug interactions, then, tend to be minimal and mild compared to other ED medications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Still, alprostadil can cause low blood pressure, so healthcare professionals will be cautious about combining alprostadil treatment <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Muse-alprostadil-1645\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">with drugs that lower blood pressure<\/span><\/a><span style=\"font-weight: 400;\"> or widen blood vessels (vasodilators).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some over-the-counter antihistamines and decongestants can cause or contribute to erectile dysfunction, so they can significantly reduce the effectiveness of ED medications. Men taking Muse might consider skipping medications containing antihistamines or decongestants like cold remedies, allergy medications, or sinus medications on days they\u2019re going to use Muse. Alcohol also contributes significantly to erectile problems, so drinking may not be a good idea.<\/span><\/p>\n<h2 id=\"how-to-avoid-side-effects\">How to avoid Muse side effects<\/h2>\n<p><span style=\"font-weight: 400;\">For people using Muse, body-wide side effects, such as low blood pressure, headache, or fainting, tend to be short-lived. On the other hand, the most common complaints people have with Muse involve issues and problems with inserting the transurethral suppository. Some men quit taking Muse because of these problems. There are ways, however, to minimize side effects, particularly insertion problems.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">1. Tell the healthcare provider about all medical conditions and medications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Most people don\u2019t realize that side effects\u2014especially the worst ones\u2014are often due to how drugs affect already-existing physical conditions. The surest way to avoid side effects with any prescription medication is to give the healthcare provider a complete medical history. This history should include all the prescription drugs, over-the-counter medicines, and even dietary supplements that are regularly taken. For Muse, the prescribing healthcare provider particularly needs to know about:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood pressure problems (<\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">high<\/span><\/a><span style=\"font-weight: 400;\"> or low blood pressure)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood problems (such as sickle cell anemia or leukemia)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A type of bone marrow cancer called multiple myeloma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Penis abnormalities<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A penile implant<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of prolonged (&gt; 4 hours) erections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any advice given by a doctor to avoid sexual activity<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">2. Take Muse as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Take the dose as prescribed by a healthcare professional. Read, understand, and follow the patient information that comes with the medicine. Do not increase or decrease the dose. If it doesn\u2019t seem to be working or side effects are a problem, the prescribing healthcare provider may be able to adjust the dose.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3. Don\u2019t overdo it<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Do not insert more than two Muse suppositories in a 24-hour period. Each pellet contains one dose (125, 250, 500, or 1000 mcg). Unfortunately, Muse does not always produce an adequate erectile response. If two suppositories taken on the same day don\u2019t work, wait until the next day.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Insert Muse suppositories as instructed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A healthcare provider will administer the first dose and teach you how to use the applicator safely to insert a Muse pellet. It\u2019s important to understand and follow these directions to avoid insertion side effects. Furthermore, <\/span><a href=\"https:\/\/www.paladin-labs.com\/our_products\/Muse_en.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">dose titration<\/span><\/a><span style=\"font-weight: 400;\"> should only be carried out under medical supervision.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">5. Stretch the penis to full length before inserting the applicator<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A healthcare provider will show you how to prepare the penis for insertion. It is important that the penis be gently pulled or stretched to full length so that the urethra is straight when the applicator is inserted. Getting this wrong may cause pain or bleeding.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">6. Be careful when separating the suppository from the applicator<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A healthcare provider will show you what to do after injecting the pellet, including a wait time and gently rocking the applicator to separate it from the pellet. This is very delicate and requires care. If it\u2019s done incorrectly, the applicator tip can scratch the urethra and cause pain or bleeding. Always keep the penis straight when removing the applicator.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">7. Roll the penis from side to side after inserting a suppository<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Urethral burning is a common side effect after inserting a Muse pellet and it\u2019s caused by the urethral tissues being irritated by the medicine. The burning is worse if the medicine is concentrated in one spot. A healthcare provider will demonstrate how to roll the penis between the hands to distribute the medicine along the urethra. If the urethra starts to burn, it may take 30 to 60 seconds of gentle rolling to distribute the medicine.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">8. Be well-rested and relaxed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">All prescription medications involve a balance between benefits and side effects. One way to successfully manage side effects is to maximize benefits. A healthcare provider will counsel patients on several tips and methods on achieving and maintaining erections, but the best medical advice is to be relaxed and well-rested. Anxiety, tiredness, stress, and drinking alcohol all contribute to erectile dysfunction. In those cases, the risk of side effects remains the same, but the benefits could be zero.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">9. Store this medicine correctly<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To realize the full benefits of this medicine, keep Muse pellets in their original foil pouch in the refrigerator (between 2\u00b0- 8\u00b0C) until ready for use. Muse pellets can be stored in their foil pouch at a cool room temperature (below 30\u00b0C) for 14 days, but heat will ruin the medicine. Do not expose Muse pellets to temperatures above 30\u00b0C.\u00a0<\/span><\/p>\n<h2 id=\"resources\">Resources<\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK542217\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alprostadil<\/span><\/a><span style=\"font-weight: 400;\">, StatPearls<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/pubchem.ncbi.nlm.nih.gov\/compound\/5280723\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alprostadil compound summary<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.pdr.net\/drug-summary\/Muse-alprostadil-1645\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alprostadil drug summary<\/span><\/a><span style=\"font-weight: 400;\">, Prescriber\u2019s Digital Reference<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4dec1dbd-c63b-4a1b-81cb-c8d29696cc40\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Caverject Impulse prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/online.epocrates.com\/drugs\/184001\/Muse\/Adult-Dosing\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Muse<\/span><\/a><span style=\"font-weight: 400;\">, Epocrates<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.paladin-labs.com\/our_products\/Muse_en.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Muse package label<\/span><\/a><span style=\"font-weight: 400;\">, Paladin Labs, Inc.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=4c55f3f9-c4cf-11df-851a-0800200c9a66\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Muse prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Muse side effects | Serious side effects | Penile pain | Low blood pressure | Priapism | How long do side effects last? | Warnings | Interactions | How to avoid side effects | Resources Muse is a prescription brand-name drug used for the treatment of erectile dysfunction. Alprostadil, the active ingredient in Muse, widens [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":45828,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,8922,12752],"coauthors":[8861],"class_list":["post-45821","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-erectile-dysfunction","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Muse side effects, interactions, warnings, and how to avoid them<\/title>\n<meta name=\"description\" content=\"Dizziness, headache, and back pain are common Muse side effects. 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