{"id":47818,"date":"2021-12-21T14:43:11","date_gmt":"2021-12-21T19:43:11","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=47818"},"modified":"2024-11-13T18:19:59","modified_gmt":"2024-11-13T23:19:59","slug":"abilify-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/abilify-side-effects\/","title":{"rendered":"Abilify side effects and how to avoid them"},"content":{"rendered":"<p><a href=\"#common-side-effects\">Abilify side effects<\/a> | <a href=\"#serious-side-effects\">Serious side effects<\/a> | <a href=\"#how-long-do-side-effects-last\">How long do side effects last?<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a> | <a href=\"#resources\">Resources<\/a><\/p>\n<p><span style=\"font-weight: 400;\">Abilify is a brand-name prescription drug approved by the FDA to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/schizophrenia-treatment-and-medications\"><span style=\"font-weight: 400;\">schizophrenia<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">major depressive disorder<\/span><\/a><span style=\"font-weight: 400;\"> (in combination with other medications), and, in children, Tourette\u2019s disorder and irritability associated with autistic disorder. Abilify can also be used alone or in combination with lithium or valproate to treat manic episodes in people diagnosed with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/bipolar-disorder-treatment-and-medications\"><span style=\"font-weight: 400;\">bipolar I disorder<\/span><\/a><span style=\"font-weight: 400;\">. Abilify is also available as Abilify MyCite (which contains a sensor), or Abilify Maintena (a monthly injection).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The active ingredient in Abilify is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aripiprazole\"><span style=\"font-weight: 400;\">aripiprazole<\/span><\/a><span style=\"font-weight: 400;\">, an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/atypical-antipsychotics\"><span style=\"font-weight: 400;\">atypical antipsychotic<\/span><\/a><span style=\"font-weight: 400;\">. The exact way Abilify works is not known, but it is thought to work by acting on dopamine and serotonin receptors in the brain. As with all antipsychotic drugs, Abilify has a number of side effects, warnings, restrictions, and drug interactions that may cause problems, so it helps to understand the downsides before starting this medicine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">RELATED: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/abilify\/what-is\"><span style=\"font-weight: 400;\">What is Abilify?<\/span><\/a><\/p>\n<h2 id=\"common-side-effects\">Common side effects of Abilify<\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/325805\/Abilify\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Abilify are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite\/weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness\/sleepiness\/sedation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Agitation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood sugar<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach problems: nausea, constipation, vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness\/lightheadedness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle and joint pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drooling\/excess salivation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Restlessness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Compulsive behaviors<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cholesterol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.pdr.net\/drug-summary\/Abilify-aripiprazole-103\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Urine leakage<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in body temperature<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever and diarrhea (in children)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In addition to these side effects, approximately <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=e8787c3f-5e41-42d1-8091-44b56346620f\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">12%<\/span><\/a><span style=\"font-weight: 400;\"> of people taking Abilify MyCite in clinical trials experienced skin rashes where the MyCite patch was affixed.<\/span><\/p>\n<h2 id=\"serious-side-effects\">Serious side effects of Abilify<\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/325805\/Abilify\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">serious side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Abilify include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drug-induced movement problems (extrapyramidal effects) including <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK519543\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">akathisia<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/emedicine.medscape.com\/article\/1151826-overview\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">tardive dyskinesia<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.ninds.nih.gov\/Disorders\/Patient-Caregiver-Education\/Fact-Sheets\/Dystonias-Fact-Sheet\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">dystonia<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suicidal thoughts\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Worsening depression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke\/mini-stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fainting and falling<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/medlineplus.gov\/genetics\/condition\/orthostatic-hypotension\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Orthostatic hypotension<\/span><\/a><span style=\"font-weight: 400;\"> (sudden drop in blood pressure when standing)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe difficulty swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Body temperature dysregulation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure (hypertension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart rate changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Intestinal obstruction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gallbladder stones<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the pancreas (pancreatitis)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low white blood cell counts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Potassium imbalance<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle damage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/emedicine.medscape.com\/article\/816018-overview\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Neuroleptic malignant syndrome<\/span><\/a><span style=\"font-weight: 400;\"> (NMS)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Patients who experience a serious reaction should notify their doctor or get emergency medical help right away. Severe allergic reactions require immediate emergency medical attention. Symptoms may include hives, difficulty breathing, or swelling around the face, lips, mouth, and tongue.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Mental Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"how-long-do-side-effects-last\">How long do side effects last?<\/h2>\n<p><span style=\"font-weight: 400;\">Aripiprazole has a half-life of <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=c040bd1d-45b7-49f2-93ea-aed7220b30ac#S5.5\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">75 hours<\/span><\/a><span style=\"font-weight: 400;\"> and its active metabolite, which works like aripiprazole, has a half-life of 94 hours. This means that many of the common side effects of aripiprazole such as headache, drowsiness, agitation, and anxiety, could take several days or even several weeks to resolve after the last dose is taken. Some side effects, such as headache and akathisia, may get better as the body adjusts to the drug.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The metabolic side effects of aripiprazole such as high blood sugar, high fats, high cholesterol, and weight gain may require treatment.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Serious side effects such as extrapyramidal symptoms, severe allergic reactions, stroke, gallbladder stones, pancreatitis, heart rate irregularities, or low white blood cell counts may require emergency medical treatment. Some, like stroke or diabetes, may have lifelong complications. Extrapyramidal symptoms can clear up within a few weeks or they may persist for years and require a medication or dosage change.<\/span><\/p>\n<h2 id=\"warnings\">Abilify contraindications &amp; warnings<\/h2>\n<h3><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Abilify is not a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/controlled-substances-act\/\"><span style=\"font-weight: 400;\">controlled substance<\/span><\/a><span style=\"font-weight: 400;\">, so healthcare professionals do not consider it an addictive drug. It also does not cause dependence, but <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3719459\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">may cause withdrawal<\/span><\/a><span style=\"font-weight: 400;\"> when stopped abruptly. People taking Abilify should consult with a healthcare professional before stopping this medicine.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Taking too much Abilify is serious but <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=c040bd1d-45b7-49f2-93ea-aed7220b30ac#S5.5\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">probably not lethal<\/span><\/a><span style=\"font-weight: 400;\">. If too much Abilify is taken, seek emergency medical care or call a poison helpline. There are some symptoms that may signal an oral Abilify overdose. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Somnolence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aggression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart rate changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood pressure changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lethargy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Convulsions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of consciousness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coma<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Restrictions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Not everyone can safely take Abilify. The hazards may be too great for some people, but others may be able to take Abilify with careful monitoring for adverse reactions. Restrictions include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Hypersensitivity<\/b><span style=\"font-weight: 400;\">: People with allergies to aripiprazole or any of the inactive ingredients of Abilify can never be given this medicine.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Older adults with dementia-related psychosis<\/b><span style=\"font-weight: 400;\"> cannot be given antipsychotic drugs like Abilify because of the increased risk of death.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Children, adolescents, and young adults <\/b><span style=\"font-weight: 400;\">are at a higher risk for worsening depression and suicide. Patients of any age require careful monitoring by both healthcare professionals and caregivers when taking Abilify.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cardiovascular disease: <\/b><span style=\"font-weight: 400;\">Patients with known cardiovascular problems such as heart attack, heart failure, ischemic heart disease, or heart rate problems will require close monitoring when taking Abilify.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cerebrovascular disease: <\/b><span style=\"font-weight: 400;\">People with a history of strokes or other cerebrovascular problems will also need careful monitoring.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Diabetes: <\/b><span style=\"font-weight: 400;\">Antipsychotics, including Abilify, can cause high blood sugar, so regular blood sugar testing is required in people with diabetes or prediabetes.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Low blood pressure, low blood volume<\/b><span style=\"font-weight: 400;\">, <\/span><b>or<\/b> <b>dehydration<\/b><span style=\"font-weight: 400;\">: Because Abilify can cause blood pressure problems, any condition that raises the risk of low blood pressure will require monitoring when Abilify is prescribed.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Seizure disorders: <\/b><span style=\"font-weight: 400;\">Abilify can cause seizures, so people with a history of seizures will be prescribed Abilify with caution.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>History of low white blood cell counts: <\/b><span style=\"font-weight: 400;\">People predisposed to problems with white blood cells will need to have regular blood tests to monitor the effects of Abilify on white blood cells.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Aspiration pneumonia: <\/b><span style=\"font-weight: 400;\">Abilify can make swallowing difficult, raising the risk that food or drink will be aspirated and possibly cause aspiration pneumonia. People who are at risk for aspiration pneumonia will require close monitoring.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Finally, aripiprazole can throw off the body\u2019s ability to regulate body temperature, resulting in hyperthermia or hypothermia. People taking Abilify then, are vulnerable to extreme environmental temperatures. They should be cautious when temperatures get too hot or too cold, dress appropriately, and even limit going outside when the weather is extreme.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Pregnancy and nursing<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Women who are pregnant or considering pregnancy should consult with a healthcare provider about the benefits and risks of taking Abilify while pregnant. There is no evidence that Abilify will harm a fetus, but when atypical antipsychotics are taken during the third trimester, <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=c040bd1d-45b7-49f2-93ea-aed7220b30ac#S5.5\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">there is a risk<\/span><\/a><span style=\"font-weight: 400;\"> that babies will be born with withdrawal symptoms and extrapyramidal side effects (involuntary movement problems).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Women who are breastfeeding should talk to their healthcare provider. Aripiprazole is present in human breast milk and there are reports of reduced milk production in lactating women and poor weight gain in nursing infants.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The U.S. Food and Drug Administration (FDA) has approved Abilify to treat schizophrenia <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/325802\/Abilify\/Peds-Dosing\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">in children<\/span><\/a><span style=\"font-weight: 400;\"> as young as 13 years of age, bipolar I disorder in children as young as 10 years of age, and Tourette syndrome or autistic disorder in children as young as 6 years of age. Because of the increased risk for suicide, children and adolescents will need to be closely watched for worsening depression, thoughts of suicide, or suicidal behaviors.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Older adults<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">People ages 65 and older can take Abilify in the same doses as younger adults, but the <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Abilify-aripiprazole-103\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">starting dose may be lower<\/span><\/a><span style=\"font-weight: 400;\">. However, there is an increased risk for falls and other injuries, so other drugs that cause sleepiness or impairment may need to be adjusted. Healthcare providers are also advised not to use Abilify in seniors with dementia-related psychosis.<\/span><\/p>\n<h2 id=\"interactions\">Abilify interactions<\/h2>\n<p><span style=\"font-weight: 400;\">Like other antipsychotic medications, Abilify has several potentially harmful drug interactions.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Antipsychotic drugs: <\/b><span style=\"font-weight: 400;\">First-generation and atypical antipsychotics produce many of the same side effects as Abilify. Combining more than one antipsychotic, then, increases the risk and possibly the severity of side effects.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>CNS depressants: <\/b><span style=\"font-weight: 400;\">Abilify reduces symptoms of schizophrenia and mania because it slows down the brain, that is, it is a central nervous system depressant. Many of the side effects such as fatigue, sleepiness, dizziness, and lightheadedness are due to the depressant effects of Abilify. Combining Abilify with other CNS depressants will worsen mental impairment and coordination problems caused by Abilify, and can slow or even stop breathing. These especially include <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sleep-aids-guide\/\"><span style=\"font-weight: 400;\">sleeping pills<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/barbiturates\"><span style=\"font-weight: 400;\">barbiturates<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anxiolytics\"><span style=\"font-weight: 400;\">anxiety medications<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/opioids\"><span style=\"font-weight: 400;\">opioid<\/span><\/a><span style=\"font-weight: 400;\"> pain relievers, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/muscle-relaxants\"><span style=\"font-weight: 400;\">muscle relaxants<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\">, and alcohol, among others.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Drugs that increase the side effects of aripiprazole:<\/b><span style=\"font-weight: 400;\"> Some drugs block the ability of the liver to break down aripiprazole and its active metabolite, causing aripiprazole to stay in the bloodstream at higher concentrations for a longer period. The strongest inhibitors of aripiprazole, such as the antidepressants <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prozac\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> (fluoxetine) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paxil\"><span style=\"font-weight: 400;\">Paxil<\/span><\/a><span style=\"font-weight: 400;\"> (paroxetine), the antifungal drugs <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ketoconazole\"><span style=\"font-weight: 400;\">ketoconazole<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/itraconazole\"><span style=\"font-weight: 400;\">itraconazole<\/span><\/a><span style=\"font-weight: 400;\">, or the heart rhythm drug quinidine may require the Abilify dose to be cut in half.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Drugs that reduce the effectiveness of aripiprazole:<\/b><span style=\"font-weight: 400;\"> Some drugs speed up the body\u2019s metabolism of aripiprazole, such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/carbamazepine\"><span style=\"font-weight: 400;\">carbamazepine<\/span><\/a><span style=\"font-weight: 400;\">. These drugs reduce the effectiveness of Abilify, so the Abilify dose may need to be increased.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Blood pressure medications:<\/b><span style=\"font-weight: 400;\"> Abilify can lower blood pressure, so careful blood pressure monitoring is required when it\u2019s combined with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">blood pressure medications<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-avoid-side-effects\">How to avoid Abilify side effects<\/h2>\n<p><span style=\"font-weight: 400;\">Most people taking antipsychotic medications will experience side effects. Abilify is no exception, though some of the most unpleasant side effects of traditional antipsychotics are less common when taking Abilify. Still, there are many good rules of thumb for avoiding or minimizing side effects when taking Abilify.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">1. Tell the healthcare provider about all medical conditions and medications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">For any prescription drug, the first line of defense against side effects is to make sure that the prescribing healthcare provider has a complete medical history. For Abilify, the healthcare provider particularly needs to know about:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes or a family history of high blood sugar<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High or low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low white blood cell counts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy or pregnancy plans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breastfeeding or plans to breastfeed<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Side effects can also be due to drug interactions. The best way to avoid drug interactions is to keep a list of all drugs being taken including prescription or over-the-counter drugs as well as dietary supplements and herbal remedies. Always share this list with the prescribing healthcare provider.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2. Keep all appointments<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Visits with the prescribing healthcare provider are another important defense against side effects. If there are side effects, keep a list and share it with the healthcare provider at each visit. The healthcare provider may be able to prescribe other drugs to help with certain side effects such as headache, constipation, or tremor\u2014or, change the dose or the medication altogether. Sleeplessness could be solved by changing the timing of each day\u2019s dose. Finally, tests may need to be regularly performed to spot problems before they turn into serious medical problems.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3. Watch for symptoms of potentially serious side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some side effects are or can develop into severe medical conditions. Abilify, unfortunately, has many severe side effects to watch out for, but there are signs and symptoms that signal there may be a serious problem, particularly:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chills<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Excessive sweating<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow, fast, or uneven heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Extreme hunger or thirst<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased urination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual urges or compulsions<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe agitation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feeling lightheaded or dizzy when standing up<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Difficulty swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uncontrolled muscle movement or shaking<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hives, rash, or swelling<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unusual bruising or bleeding<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If any of these problems are noticed while taking Abilify, immediately call a healthcare professional for medical advice or seek emergency medical attention when needed.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Take Abilify as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Take Abilify exactly as instructed. Do not change the doses or stop taking Abilify without getting the medical advice of the prescribing healthcare provider.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">5. Do not miss doses<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Abilify doses need to be taken daily to provide maximum therapeutic benefits. If a dose is missed, take it as soon as it\u2019s remembered. If it\u2019s almost time for the next dose, however, skip the missed dose and take the next dose on time. Do not double up on doses. If missing doses becomes a problem, a pharmacist can provide useful tools to help remember doses such as alarms, pillboxes, smartphone apps, and even pill bottle caps that have alarms. Or, you may want to talk to your doctor about other forms of Abilify such as Abilify MyCite or Abilify Maintena.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">6. Don\u2019t drink alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">As a drug that slows down the brain, Abilify doesn\u2019t mix well with alcohol. The combination will worsen mental impairment and increase the risk of falling and accidents. It can also decrease blood pressure and cause breathing to slow or even stop.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">7. Be careful about driving and other risky activities<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Abilify can cause sleepiness, blurred vision, and mental impairment. Use good judgment about driving or engaging in risky activities. Do not drive until you know how Abilify affects you. You shouldn\u2019t drive if you experience side effects such as blurred vision.\u00a0<\/span><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abilify side effects | Serious side effects | How long do side effects last? | Warnings | Interactions | How to avoid side effects | Resources Abilify is a brand-name prescription drug approved by the FDA to treat schizophrenia, major depressive disorder (in combination with other medications), and, in children, Tourette\u2019s disorder and irritability associated [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":47820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[451,788,12752,450],"coauthors":[8861],"class_list":["post-47818","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-depression","tag-drug-safety","tag-medication-side-effects","tag-mental-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Abilify side effects and how to avoid them | SingleCare<\/title>\n<meta name=\"description\" content=\"Headache, weight gain, and Insomnia are common Abilify side effects. 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