{"id":47959,"date":"2022-01-14T09:30:41","date_gmt":"2022-01-14T14:30:41","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=47959"},"modified":"2026-08-11T18:45:22","modified_gmt":"2026-08-11T22:45:22","slug":"best-weight-loss-pills","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/best-weight-loss-pills\/","title":{"rendered":"Could one of these 7 prescription weight-loss pills be right for you?"},"content":{"rendered":"<p>About <a href=\"https:\/\/www.singlecare.com\/blog\/news\/obesity-statistics\/\">40% of adult Americans<\/a> are obese (defined by having a body mass index over 30)\u2014and that number is expected to grow to 50% by 2030, according to a Harvard report. Because of the myriad health conditions that all those extra pounds can cause, many are wondering: Can losing weight be as simple as taking a pill?<\/p>\n<p>Prescription weight-loss pills aren\u2019t a magic bullet for obesity treatment. But when used in conjunction with a <a href=\"https:\/\/www.singlecare.com\/blog\/best-diets-by-health-condition\/\">healthy diet<\/a>, restricting calorie intake, and exercise, they can help many people on their weight loss journey. On average, after one year of use, people taking prescription weight-loss medication lose 3% to 12% more body weight than people who use diet and exercise alone, according to the National Institute of Diabetes and Digestive and Kidney Diseases. This may not sound that impressive, but that difference can be enough to help reduce your risk of heart attack, stroke, and diabetes.<\/p>\n<p>\u201cWe live in what we now call an obesogenic environment,\u201d says Juliana Simonetti, MD, co-director of the Comprehensive Weight Management Program at the University of Utah. \u201cPhysiologically speaking, we\u2019re built to hold on to calories so we can survive things like famine and war. We also eat many calorie-dense foods and have 24\/7 access to food. All these things promote weight gain. Weight-loss medications can help us overcome some of that physiology and control our appetites so we can lose weight.\u201d<\/p>\n<p>So, what are the best weight-loss pills out there? Read on to find out.<\/p>\n<h2 id=\"7-fda-approved-weight-loss-pills\">7 FDA-approved weight-loss pills<\/h2>\n<p>Prescription drugs for weight loss work in different ways. Some work by targeting areas of the brain that regulate appetite. By altering certain brain chemicals, these drugs act as an <a href=\"https:\/\/www.singlecare.com\/drug-classes\/appetite-suppressants\">appetite suppressant<\/a> and\/or increase feelings of fullness. Some drugs use a different pathway, helping to interfere with your body\u2019s absorption of fat. Because obesity can be a chronic health issue, many of these drugs are meant to be used long term, even after you reach your ideal weight\u2014assuming you\u2019re responding to the medication in the first place.<\/p>\n<p>\u201cA common analogy is blood pressure medication,\u201d says <a href=\"https:\/\/www.ethosendo.com\/about-aleem-kanji-md\/\">Aleem Kanji, MD<\/a>, a board-certified endocrinologist and obesity medicine specialist with Ethos Endocrinology in Houston, Texas. \u201cMost would expect high blood pressure to return if medication is discontinued. Obesity is the same. It is a chronic disease that requires chronic therapy.\u201d<\/p>\n<p>But not everyone is a candidate for weight-loss drugs. Use of prescription weight-loss medications is typically reserved for people who:<\/p>\n<ul>\n<li>Have a BMI (body mass index) of 27 or greater with the presence of a weight-related disease or complication\u2014for example, Type 2 diabetes, high cholesterol, or high blood pressure<\/li>\n<li>Have a BMI of 30 or greater, even without a weight-related disease<\/li>\n<\/ul>\n<p>A BMI of 25-30 puts a person in the <a href=\"https:\/\/www.cdc.gov\/bmi\/adult-calculator\/bmi-categories.html\">overweight category<\/a>. A BMI over 30 is considered obese. Your primary care physician can prescribe a weight-loss medication, as can an obesity medicine doctor or endocrinologist, who treats weight-related health conditions like diabetes. Currently, there are only a handful of weight-loss medications approved by the U.S. Food and Drug Administration (FDA).<\/p>\n<p>If you prefer to avoid injectable medications like <a href=\"https:\/\/www.singlecare.com\/prescription\/zepbound\">Zepbound (tirzepatide)<\/a> and <a href=\"https:\/\/www.singlecare.com\/prescription\/victoza\">Victoza (liraglutide)<\/a>, several weight-loss pills are available instead. The most commonly used ones include the following:<\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/resources\/weight-loss\">Weight-loss resources<\/a><\/p>\n<h3 id=\"1-lomaira-adipex-phentermine\">1. Lomaira, Adipex (phentermine)<\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/phentermine-for-weight-loss\/\">Phentermine<\/a> is the <a href=\"https:\/\/www.kpwashingtonresearch.org\/news-and-events\/blog\/2019\/mar-2019\/Using_phentermine_for_weight_loss_more_than_3_months_seems_safe_and_effective\">most commonly prescribed weight-loss medication<\/a> used in this country. It helps suppress appetite and make you feel fuller for longer. Phentermine is an amphetamine-like stimulant drug that can affect your heart. As such, it\u2019s generally used for the short term (usually 12 weeks at a time).<\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/phentermine-side-effects\/\">Side effects<\/a> can run the gamut and may include:<\/p>\n<ul>\n<li>Shortness of breath<\/li>\n<li>Chest pain<\/li>\n<li>Increased blood pressure<\/li>\n<li>Increased heart rate\/pounding heart<\/li>\n<li>Restlessness\/problems sleeping<\/li>\n<li>Dry mouth<\/li>\n<li>Dizziness<\/li>\n<li>Changes in mood<\/li>\n<li>Itchiness<\/li>\n<\/ul>\n<p>In <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3791337\/\">one study<\/a> looking at nearly 800 people with BMIs of over 25, 45.6% of people were able to lose 5% or more of their starting body weight after 12 weeks of phentermine use.<\/p>\n<p>According to the drug\u2019s <a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/085128s065lbl.pdf\">FDA prescription information<\/a>, certain people should not use the drug, including:<\/p>\n<ul>\n<li>Those with cardiovascular disease (including uncontrolled high blood pressure and heart arrhythmias)<\/li>\n<li>People who have taken a <a href=\"https:\/\/www.singlecare.com\/blog\/maois\/\">monoamine oxidase inhibitor<\/a> (MAOI\u2014a type of drug that\u2019s sometimes used to treat depression) within 14 days<\/li>\n<li>Pregnant or nursing women<\/li>\n<li>People with glaucoma<\/li>\n<li>Those with an overactive thyroid<\/li>\n<li>People who have mood disorders, especially manic\/depressive moods or agitation<\/li>\n<\/ul>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lomaira\">Get Lomaira coupon<\/a> <a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/adipex-p\">Get Adipex coupon<\/a><\/p>\n<h3 id=\"2-qsymia-phentermine-topiramate\">2. Qsymia (phentermine\/topiramate)<\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/qsymia\/what-is\">Qsymia<\/a> combines a low dose of phentermine with <a href=\"https:\/\/www.singlecare.com\/prescription\/topiramate\/what-is\">topiramate<\/a>, a drug used to treat seizures and migraines. \u201cThe phentermine helps suppress appetite and the topiramate appears to reduce cravings,\u201d says <a href=\"https:\/\/healthcare.utah.edu\/find-a-doctor\/juliana-s-simonetti\">Dr. Simonetti<\/a>. \u201cBecause we use a low dose of phentermine, Qsymia can be used over a long period of time and typically produces good results.\u201d<\/p>\n<p>Qsymia comes in a variety of <a href=\"https:\/\/qsymia.com\/patient\/resources\/taking-qsymia\/\">dosages<\/a>.<\/p>\n<ul>\n<li>For the first two weeks, your provider will prescribe a dose of 3.75\/23 mg (3.75 mg of phentermine, 23 mg of topiramate) taken in capsule form once a day.<\/li>\n<li>Starting in week three, you\u2019ll be prescribed a 7.5\/46 mg capsule. If you\u2019ve lost at least 3% of your overall body weight by the end of 12 weeks, you\u2019ll stay on this dose indefinitely.<\/li>\n<li>If not, your healthcare provider may up the dose to a maximum of 15\/92 mg.<\/li>\n<\/ul>\n\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our weight management newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Weight Management Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" role=\"status\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t\n<p>Qsymia may cause some of the same <a href=\"https:\/\/www.singlecare.com\/blog\/qsymia-side-effects\/\">side effects<\/a> as other medications containing phentermine, as well as possible additional side effects due to the topiramate. One of the biggest dangers of Qsymia is its link to birth defects. It\u2019s imperative that you talk to your doctor about preventing pregnancy if you want to try Qsymia and to take monthly pregnancy tests if you\u2019re at risk for pregnancy. And while Qsymia can have other serious side effects, including suicidal thoughts, increased irritability, worsening depression\/anxiety, and heart and eye problems, the most common ones include:<\/p>\n<ul>\n<li>Tingling or numbness in hands, feet, arms, and face<\/li>\n<li>Dry mouth<\/li>\n<li>Constipation<\/li>\n<li>Trouble sleeping<\/li>\n<li>Dizziness<\/li>\n<li>Changes in the way food tastes<\/li>\n<\/ul>\n<p>Research shows that Qsymia can help people lose weight, even at low doses (although<\/p>\n<p>the higher doses produce more weight loss). In <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3814438\/\">one study<\/a>, people who took the average dose of Qsymia (7.5\/46 mg) lost 7.8% of their body weight, while those taking the highest dose (15\/92 mg) lost nearly 10%.<\/p>\n<p>Qsymia may not be right for certain groups of people, including:<\/p>\n<ul>\n<li>Pregnant\/nursing women or women trying to conceive<\/li>\n<li>People with cardiovascular problems<\/li>\n<li>Those with glaucoma<\/li>\n<li>People who drink heavily<\/li>\n<li>People with an anxiety disorder<\/li>\n<li>Those with uncontrolled hyperthyroidism (an overactive thyroid)<\/li>\n<li>Those with prior issues of kidney stones<\/li>\n<li>People who have taken an MAOI within 14 days<\/li>\n<\/ul>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/qsymia\">Get Qsymia coupon<\/a><\/p>\n<h3 id=\"3-saxenda-liraglutide\">3. Saxenda (liraglutide)<\/h3>\n<p>The active ingredient in <a href=\"https:\/\/www.singlecare.com\/prescription\/saxenda\/what-is\">Saxenda<\/a> is a <a href=\"https:\/\/www.singlecare.com\/blog\/glp-1-agonists\/\">glucagon-like peptide-1 (GLP-1) receptor agonist<\/a>, a class of drugs used to treat Type 2 diabetes and keep blood sugar levels in check. GLP-1 is a hormone your body naturally makes that\u2019s released in response to food and helps regulate your appetite. <a href=\"https:\/\/www.novomedlink.com\/obesity\/products\/treatments\/saxenda\/about\/how-saxenda-works.html\">Saxenda<\/a> and its <a href=\"https:\/\/www.singlecare.com\/blog\/news\/fda-approves-first-generic-glp-1-for-weight-loss\/\">FDA-approved generic, liraglutide<\/a>, mimic the action of GLP-1 in your body, but it lasts much longer than naturally occurring GLP-1. As such, it can help suppress hunger longer and slow the movement of food emptying from your stomach. Both factors can help you eat less overall and lose weight.<\/p>\n<p>\u201cI have patients tell me that they never left food on their plates before, but with Saxenda, they\u2019re eating less and getting full quickly,\u201d comments Dr. Simonetti. Saxenda and liraglutide are also <a href=\"https:\/\/www.prnewswire.com\/news-releases\/fda-approves-saxenda-for-the-treatment-of-obesity-in-adolescents-aged-12-17-301186800.html\">approved<\/a> for use in adolescents.<\/p>\n<p>Saxenda is a daily injectable with dosing increasing from 0.6 mg in week one to 3.0 mg by week five. While Saxenda can cause some serious <a href=\"https:\/\/www.singlecare.com\/blog\/saxenda-side-effects\/\">side effects<\/a>, such as inflammation of the pancreas (called pancreatitis), gallbladder problems, and mood changes, the most common side effects include:<\/p>\n<ul>\n<li>Nausea<\/li>\n<li>Diarrhea<\/li>\n<li>Constipation<\/li>\n<li>Vomiting<\/li>\n<li>Low blood sugar (hypoglycemia)<\/li>\n<li>Headache<\/li>\n<li>Dizziness<\/li>\n<li>Tiredness<\/li>\n<li>Stomach pain<\/li>\n<\/ul>\n<p>A <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5358074\/\">study<\/a> following more than 500 people found that 50.5% of those taking liraglutide were able to lose at least 5% of their body weight during the study period versus 21.8% who took a placebo. Even more impressive, 26.1% of the drug group were able to lose 10% of their body weight compared to just 6.3% in the placebo group.<\/p>\n<p>Saxenda carries a <a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\">black box warning<\/a> (the FDA\u2019s strongest alert to consumers and healthcare providers about very serious side effects) due to the fact that animal studies have linked liraglutide and medicines like it to certain <a href=\"https:\/\/www.singlecare.com\/blog\/january-thyroid-awareness-month\/\">thyroid tumors and thyroid cancer<\/a>. It\u2019s important that you do not use Saxenda if you have had these conditions or have a family history of them. Saxenda isn\u2019t appropriate for pregnant or nursing women. Talk to your healthcare provider if you\u2019re taking medicines that act like GLP-1 receptor agonists. Because Saxenda can slow stomach emptying, it\u2019s also important to ask your doctor how that may affect other prescription and over-the-counter medicines you take.<\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/saxenda\">Get Saxenda coupon<\/a><\/p>\n<h3 id=\"4-contrave-naltrexone-and-bupropion\">4. Contrave (naltrexone and bupropion)<\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/contrave-vs-phentermine\/\">Contrave<\/a> combines <a href=\"https:\/\/www.singlecare.com\/prescription\/naltrexone-hcl\/what-is\">naltrexone<\/a> (used to treat substance abuse) and <a href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl\/what-is\">bupropion<\/a> (an antidepressant that\u2019s marketed under the brand name Wellbutrin). It\u2019s thought to work on the brain to regulate appetite and cravings.<\/p>\n<p>Like a lot of weight-loss medications, your dose of Contrave will start out low and<\/p>\n<p>increase over time.<\/p>\n<ul>\n<li>Week one: One pill in the morning.<\/li>\n<li>Week two: Two pills, one in the morning and the other at night.<\/li>\n<li>Week three: Two pills in the morning and one in the evening.<\/li>\n<li>Week four and beyond: Four pills per day\u2014two in the morning, two in the evening<\/li>\n<\/ul>\n<p>Contrave can potentially produce serious <a href=\"https:\/\/www.singlecare.com\/blog\/contrave-side-effects\/\">side effects<\/a>, such as suicidal thoughts and seizures, but the most common side effects are:<\/p>\n<ul>\n<li>Nausea<\/li>\n<li>Constipation<\/li>\n<li>Headache<\/li>\n<li>Vomiting<\/li>\n<li>Dizziness<\/li>\n<li>Trouble sleeping<\/li>\n<li>Dry mouth<\/li>\n<li>Diarrhea<\/li>\n<\/ul>\n<p>One <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4459776\/\">study<\/a> examined how Contrave contributed to weight loss when used in conjunction with behavior therapy (sessions with registered dietitians, exercise specialists, and psychologists). Compared to those receiving a placebo and therapy, 1.5 times as many people in the Contrave\/therapy group were able to lose at least 5% of their body weight compared to those in the placebo group.<\/p>\n<p>Contrave should <a href=\"https:\/\/www.contravehcp.com\/dosing\/\">not be used<\/a> in people who:<\/p>\n<ul>\n<li>Have uncontrolled hypertension<\/li>\n<li>Have seizures<\/li>\n<li>Are pregnant<\/li>\n<li>Use other drugs containing bupropion<\/li>\n<li>Are withdrawing from alcohol and certain other drugs<\/li>\n<li>Have used an MAOI within 14 days<\/li>\n<\/ul>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/contrave\">Get Contrave coupon<\/a><\/p>\n<h3 id=\"5-xenical-alli-orlistat\">5. Xenical, Alli (orlistat)<\/h3>\n<p>Orlistat is a <a href=\"https:\/\/www.singlecare.com\/drug-classes\/lipase-inhibitors\">lipase inhibitor<\/a>, meaning it blocks the enzyme that helps absorb some of the fats in the foods you eat. Meaning, less of the fat you consume makes it into fat cells to become stubborn belly fat. Orlistat comes in two different strengths\u2014an over-the-counter 60mg strength marketed as Alli and a prescription-strength (120mg) marketed as Xenical.<\/p>\n<p>Xencal is taken by mouth three times a day, with or within one hour of a meal that contains fat.<\/p>\n<p>The most common <a href=\"https:\/\/xenical.com\/patients.html\">side effects<\/a> of Xenical are:<\/p>\n<ul>\n<li>Oily stools<\/li>\n<li>Gas with an oily discharge<\/li>\n<li>Loose stools<\/li>\n<li>Urgent need to have a bowel movement\/unable to control bowel movement<\/li>\n<li>More frequent bowel movements<\/li>\n<\/ul>\n<p>Xenical is not as effective as some other weight-loss prescriptions. <a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1111\/ijcp.13399\">One study<\/a> comparing orlistat with liraglutide found that those using the latter were able to lose more than twice as much weight as those taking orlistat.<\/p>\n<p>People who should not take Xenical are people who:<\/p>\n<ul>\n<li>Are pregnant or breastfeeding<\/li>\n<li>Have gallbladder problems<\/li>\n<li>Have food absorption issues<\/li>\n<\/ul>\n<p>Xenical can affect the absorption of not just fat, but also of vitamins from the foods you eat. Make sure you talk to your healthcare provider about taking a multivitamin supplement.<\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/xenical\">Get Xenical coupon<\/a> <a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/alli\">Get Alli coupon<\/a><\/p>\n<h3 id=\"6-wegovy-semaglutide\">6. Wegovy (semaglutide)<\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/news\/wegovy-semaglutide-fda-approval\/\">Wegovy<\/a> is the first GLP-1 pill to be FDA approved for weight loss. It works much the same way as Saxenda, by mimicking the action of the hormone GLP-1 to suppress hunger. Previously, it was available only in injectable form.<\/p>\n<p>Some of the most common side effects include:<\/p>\n<ul>\n<li>Nausea<\/li>\n<li>Diarrhea<\/li>\n<li>Constipation<\/li>\n<li>Vomiting<\/li>\n<li>Stomach pain<\/li>\n<li>Indigestion<\/li>\n<li>Headache<\/li>\n<li>Fatigue<\/li>\n<li>Belching\/flatulence<\/li>\n<li>Low blood sugar (if you have Type 2 diabetes)<\/li>\n<\/ul>\n<p>The Wegovy pill has about the same efficacy as the 2.4 mg injectable formulation (the highest dose of Wegovy injection), according to the manufacturer: A loss of <a href=\"https:\/\/www.novomedlink.com\/obesity\/products\/treatments\/wegovy\/efficacy-safety\/chronic-weight-management.html\">14%-15% of starting body weight<\/a>.<\/p>\n<p>Like Saxenda, Wegovy carries a black box warning due to the possibility that it may increase your risk of certain thyroid tumors and cancer. Pancreatitis, gallbladder disease, kidney injury, low blood sugar, and other conditions have also been reported with <a href=\"https:\/\/www.novomedlink.com\/obesity\/products\/treatments\/wegovy.html\">Wegovy use<\/a>.<\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\">Get Wegovy coupon<\/a><\/p>\n<h3 id=\"7-foundayo-orforglipron\">7. Foundayo (orforglipron)<\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/news\/fda-approves-foundayo\/\">Foundayo<\/a> (orforglipron) is the second GLP-1 pill to be approved for weight loss. It\u2019s a new GLP-1 that can be taken any time of day with food or on an empty stomach.<\/p>\n<p>Some of the most common side effects include:<\/p>\n<ul>\n<li>Nausea<\/li>\n<li>Constipation<\/li>\n<li>Diarrhea<\/li>\n<li>Vomiting<\/li>\n<li>Indigestion<\/li>\n<li>Stomach (abdominal) pain<\/li>\n<li>Headache<\/li>\n<li>Swollen belly<\/li>\n<li>Feeling tired<\/li>\n<li>Belching<\/li>\n<li>Heartburn<\/li>\n<li>Gas<\/li>\n<li>Hair loss<\/li>\n<\/ul>\n<p>In a head-to-head study by its manufacturer <a href=\"https:\/\/investor.lilly.com\/news-releases\/news-release-details\/lillys-oral-glp-1-orforglipron-superior-oral-semaglutide-head\">Eli Lily<\/a>, Foundayo showed superior weight loss compared to Wegovy, with an average weight loss of\u00a09.2% vs 5.3% at the highest dose (19.7 pounds vs 11 pounds over 72 weeks).<\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/foundayo\">Get Foundayo coupon<\/a><\/p>\n<h2 id=\"safety-information\">Safety information<\/h2>\n<p>Prescription weight-loss drugs can be effective, but they aren\u2019t risk-free. While most side effects are mild, some can be very serious and will vary based on the drug and the person using it. According to <a href=\"https:\/\/hartfordhospital.org\/find-a-doctor\/physician-detail?id=003j000000GCyb5AAD\">Devika Umashanker, MD<\/a>, an obesity medicine specialist with Hartford HealthCare\u2019s Medical and Surgical Weight Loss Program, some red flags that require a doctor\u2019s attention are:<\/p>\n<ul>\n<li>Increased heart rate that doesn\u2019t slow down<\/li>\n<li>Shortness of breath<\/li>\n<li>Kidney stones (symptoms include abdominal pain, back pain, and\/or blood in the urine)<\/li>\n<li>Seizures<\/li>\n<li>Low blood sugar (symptoms are dizziness, feeling clammy, and increased heart rate)<\/li>\n<li>Swelling or a lump\u2014aka nodule\u2014around the front of your neck (this can indicate a thyroid problem)<\/li>\n<li>All-over severe stomach pain (this could signal pancreatitis)<\/li>\n<\/ul>\n<p>Of course, your physician should be monitoring you while you\u2019re on the medication, but if something is worrying you, reach out. \u201cI tell my patients, you know your body best,\u201d Dr. Umashanker explains. \u201cIf something feels off, give us a call.\u201d<\/p>\n<p>If you decide to stop taking the drug for any reason, speak to your doctor about how to do so safely. Quitting cold turkey can be dangerous with some of these drugs. \u201cContrave, for example, has to be gradually reduced,\u201d cautions Dr. Umashanker, \u201cto reduce the risk of seizures.\u201d<\/p>\n<h2 id=\"what-is-the-best-prescription-weight-loss-pill-for-you\">What is the best prescription weight-loss pill for you?<\/h2>\n<p>Many people choose pills over injectables because they\u2019re convenient, easy to take, and needle-free, reducing anxiety linked to injections. And now for the million-dollar question: Given the choices, which are the best diet pills based on safety and effectiveness? Turns out there\u2019s no one best answer.<\/p>\n<p>\u201cLooking strictly at the studies, Wegovy has the highest percent of body weight loss,\u201d Dr. Kanji notes. \u201cHowever, we have to keep in mind that each study had a different patient population and method. It\u2019s also difficult to generalize safety profiles, as it should come down to each individual&#8217;s situation. For example, a person with a history of pancreatitis would want to avoid Wegovy and Saxenda but may be fine with Qsymia. On the other hand, a person with a history of kidney stones may want to avoid Qsymia.\u201d<\/p>\n<p>It\u2019s important to remember that these drugs should be used in combination with natural lifestyle changes, like diet and exercise, for optimal results. Some tips to help you get to a healthy weight include:<\/p>\n<ul>\n<li><b>Eat high-fiber, protein-rich foods <\/b>to feel more satisfied. Consider trying a low-carb, low-fat diet\u2014or limiting your intake of processed <a href=\"https:\/\/www.singlecare.com\/blog\/what-are-carbohydrates\/\">carbohydrates<\/a> (think white bread, sweets, pasta).<\/li>\n<li><b>Focus on making plant-based diet choices.<\/b> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7533223\/\">Research<\/a> shows that it can be beneficial for weight loss, and they contain lots of healthy antioxidants.<\/li>\n<li><b>Don\u2019t label foods good or bad. <\/b>Instead, aim to make 80% to 90% of what you eat healthy.<\/li>\n<li><b>Get regular exercise<\/b> to burn calories, decrease body fat, boost metabolism, and increase muscle mass. Experts say you should aim for 150 minutes of moderate- intensity activity (for example, brisk walking or biking) a week.<\/li>\n<\/ul>\n<p>And steer clear of any pill or herbal remedy that claims to be the best weight-loss supplement, such as:<\/p>\n<ul>\n<li>Green coffee bean extract<\/li>\n<li>Konjac (a root)<\/li>\n<li>L-carnitine (an amino acid derivative)<\/li>\n<li>Green tea extract<\/li>\n<li>Garcinia cambogia (a fruit)<\/li>\n<li>Conjugated linoleic acid (CLA)<\/li>\n<\/ul>\n<p>While these dietary supplements may claim to promote fat loss and fat burning and help you lose weight, well-conducted scientific studies don\u2019t always bear this out. What\u2019s more, these diet supplements are not regulated by the FDA, which means you can\u2019t be sure of exactly what\u2019s in them. Even natural ingredients at certain levels can be toxic to some people.<\/p>\n<p>Lastly, many of these prescription medications can be prohibitively expensive, and <a href=\"https:\/\/www.singlecare.com\/blog\/obesity-and-health-insurance\/\">not all are covered by insurance<\/a>. Use your <a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\">SingleCare card<\/a> to lower costs whenever you can.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>About 40% of adult Americans are obese (defined by having a body mass index over 30)\u2014and that number is expected to grow to 50% by 2030, according to a Harvard report. Because of the myriad health conditions that all those extra pounds can cause, many are wondering: Can losing weight be as simple as taking [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":47941,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,21067,4350,9825],"coauthors":[10462],"class_list":["post-47959","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-glp-1-drugs","tag-prescription-savings","tag-weight-loss","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.3 (Yoast SEO v28.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>7 safe and effective weight-loss pills<\/title>\n<meta name=\"description\" content=\"For the 42% of Americans who have obesity, weight loss medication is sometimes necessary. 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