{"id":48243,"date":"2022-02-01T09:30:50","date_gmt":"2022-02-01T14:30:50","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=48243"},"modified":"2025-09-12T12:35:19","modified_gmt":"2025-09-12T16:35:19","slug":"lipitor-facts","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/lipitor-facts\/","title":{"rendered":"13 things you might not know about Lipitor"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-cholesterol-diet\/\"><span style=\"font-weight: 400;\">healthy diet<\/span><\/a><span style=\"font-weight: 400;\"> and exercise are important for heart health\u2014partially because they help keep cholesterol levels in check. But, for some people, lifestyle changes aren\u2019t enough. <\/span><span style=\"font-weight: 400;\">Medication<\/span><span style=\"font-weight: 400;\"> may be necessary to avoid heart disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Statins are among the most common medications prescribed to lower cholesterol. This <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/statins\"><span style=\"font-weight: 400;\">class of medication<\/span><\/a><span style=\"font-weight: 400;\"> helps to decrease low-density lipoprotein (LDL) cholesterol (also known as bad cholesterol) and triglycerides in your blood. At the same time, statins increase high-density lipoprotein (HDL) cholesterol (aka good cholesterol). Statins work by blocking a substance the liver needs to make cholesterol. Lipitor is a statin.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/lipitor\/what-is\"><b>What is Lipitor used for?<\/b><\/a><\/p>\n<h2 id=\"13-lipitor-facts-to-know-before-taking-your-rx\"><span style=\"font-weight: 400;\">13 Lipitor facts to know before taking your Rx<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Now that you know the basics, here are some facts about Lipitor.<\/span><\/p>\n<h3 id=\"1-lipitor-is-the-most-prescribed-statin\"><span style=\"font-weight: 400;\">1. Lipitor is the most prescribed statin<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Lipitor (<\/span><span style=\"font-weight: 400;\">atorvastatin) is a type of statin. More than <\/span><a href=\"https:\/\/www.hopkinsmedicine.org\/health\/wellness-and-prevention\/how-statin-drugs-protect-the-heart\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">200 million people<\/span><\/a><span style=\"font-weight: 400;\"> worldwide take statins, with Lipitor being the <\/span><a href=\"https:\/\/www.drugwatch.com\/lipitor\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">most prescribed type<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"2-lipitor-is-easy-to-fit-into-your-schedule\"><span style=\"font-weight: 400;\">2. Lipitor is easy to fit into your schedule<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Short-acting statins (that have a half-life of less than six hours) <\/span><a href=\"https:\/\/www.drugs.com\/medical-answers\/does-lipitor-work-better-if-you-take-it-at-night-416127\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">should be taken at night<\/span><\/a><span style=\"font-weight: 400;\"> because cholesterol production is thought to be highest while you sleep. Because Lipitor is a long-acting statin, with a half-life of 14 hours, you can take it whenever you want\u2014as long as you pick the same time each day. Lipitor is typically taken <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lipitor\/dosage\"><span style=\"font-weight: 400;\">once per day<\/span><\/a><span style=\"font-weight: 400;\"> in pill form. Lipitor dosages range from 10 mg to 80 mg.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cSome people choose to take it at night because it\u2019s easier to remember to take it then,\u201d says <\/span><a href=\"https:\/\/shoutoutarizona.com\/meet-pri-hennis-integrative-medicine-certified-life-coach\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Pri Hennis<\/span><\/a><span style=\"font-weight: 400;\">, MD, physician with the <\/span><a href=\"https:\/\/www.va.gov\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">U.S. Department of Veterans Affairs<\/span><\/a><span style=\"font-weight: 400;\"> in Phoenix, Arizona. \u201cIf you have problems sleeping [from Lipitor], consider taking it in the daytime instead.\u201d Follow your healthcare provider\u2019s directions, and check with them before making changes or stopping your medication.<\/span><\/p>\n<h3 id=\"3-lipitor-can-reduce-ldl-c-by-up-to-60\"><span style=\"font-weight: 400;\">3. Lipitor can reduce LDL-C by up to 60%<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Statins have been prescribed for a long time, so there\u2019s a lot of data showing they have a good safety profile. Lipitor has been <\/span><a href=\"https:\/\/labeling.pfizer.com\/showlabeling.aspx?id=587\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">FDA-approved since 1996<\/span><\/a><span style=\"font-weight: 400;\">. This means Lipitor <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25760954\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">works well<\/span><\/a><span style=\"font-weight: 400;\">, and is well-tolerated by most people. For those who do experience Lipitor <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/lipitor-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\">, some of the more common ones include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain and swelling of the throat and nasal passages<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Joint pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain in the extremities<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary tract infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach upset<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle pain, tenderness, or weakness\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle spasms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In many cases, these are mild and temporary, as the body adjusts to the drug. For most people, the benefits far outweigh any potential risks.<\/span><\/p>\n<h3 id=\"4-lipitor-doesn-t-cause-arthritis-or-joint-damage\"><span style=\"font-weight: 400;\">4. Lipitor doesn&#8217;t cause arthritis or joint damage<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">You shouldn\u2019t experience new pain in your joints because of a statin, and Lipitor does not cause arthritis. However, muscle discomfort, such as soreness, tiredness, or weakness, is a common complaint. While this muscle pain has been established as a legitimate side effect of Lipitor, some research has shown a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/nocebo-effect\/\"><span style=\"font-weight: 400;\">\u201cnocebo\u201d effect<\/span><\/a><span style=\"font-weight: 400;\">, indicating that those who expected to experience muscle pain were more likely to experience it, even when given a placebo.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In very rare circumstances, a condition called <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/rhabdomyolysis\/\"><span style=\"font-weight: 400;\">rhabdomyolysis<\/span><\/a><span style=\"font-weight: 400;\"> involving life-threatening muscle damage may occur, especially when statins are taken in high doses or in combination with certain drugs. Rhabdomyolysis can cause severe muscle pain, liver damage, and kidney failure, and may be fatal. Contact your healthcare provider if you experience new, severe pain.<\/span><\/p>\n<h3 id=\"5-you-might-need-a-vitamin-d-supplement\"><span style=\"font-weight: 400;\">5. You might need a vitamin D supplement<\/span><\/h3>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2214623716300503\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Studies suggest<\/span><\/a><span style=\"font-weight: 400;\"> that low vitamin D levels may be associated with statin myopathy (muscle problems from taking Lipitor). A vitamin D supplement may help to improve this soreness. If you experience muscle discomfort after starting Lipitor, ask your healthcare provider about having your vitamin D levels checked. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-much-vitamin-d-should-i-take\/\"><span style=\"font-weight: 400;\">If you\u2019re deficient, you can try supplementation<\/span><\/a><span style=\"font-weight: 400;\">\u00a0or ask about switching to another statin.<\/span><\/p>\n<h3 id=\"6-lipitor-won-t-usually-hurt-your-liver\"><span style=\"font-weight: 400;\">6. Lipitor won\u2019t usually hurt your liver<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There is a Lipitor warning for liver enzyme abnormalities. While liver damage is a possible serious side effect of Lipitor, one<\/span> <span style=\"font-weight: 400;\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3983981\/\">study<\/a><\/span><span style=\"font-weight: 400;\"> found that this risk is extremely low and does not prevent most people from taking statins. According to the <\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-cholesterol\/in-depth\/statin-side-effects\/art-20046013\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Mayo Clinic<\/span><\/a><span style=\"font-weight: 400;\">, the risk of serious side effects from statins is extremely low\u2014a few cases per million people taking statins\u2014but they can occur. Your healthcare provider may run liver tests before starting you on statins to be sure they are safe for you. As an added precaution, consider <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/statins-and-alcohol\/\"><span style=\"font-weight: 400;\">limiting alcohol<\/span><\/a><span style=\"font-weight: 400;\"> or avoiding it altogether when taking atorvastatin, as it can increase the risk of liver problems.<\/span><\/p>\n<h3 id=\"7-lipitor-may-increase-your-risk-for-type-2-diabetes\"><span style=\"font-weight: 400;\">7. Lipitor may increase your risk for Type 2 diabetes<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Statins may increase blood sugar, which has the potential to cause or worsen Type 2 diabetes. The risk appears higher for those who already have\u00a0<\/span><span style=\"box-sizing: border-box; margin: 0px; padding: 0px;\">higher-than-normal<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/normal-blood-glucose-levels\/\"><span style=\"font-weight: 400;\">blood sugar levels<\/span><\/a><span style=\"font-weight: 400;\">, such as those who are prediabetic or diabetic.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Though, generally the benefits of statins for preventing cardiovascular disease in people with Type 2 diabetes tend to outweigh the risks of the slight blood sugar increase. If you\u2019re a high-risk group, discuss the pros and cons with your prescribing physician.<\/span><\/p>\n<h3 id=\"8-lipitor-and-grapefruit-don-t-mix\"><span style=\"font-weight: 400;\">8. Lipitor and grapefruit don\u2019t mix<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Grapefruit can interfere with statins. You may not need to eliminate grapefruit entirely from your diet, but it will need to be limited. Ask your healthcare provider how much grapefruit you can safely consume with your medication.<\/span><\/p>\n<h3 id=\"9-your-morning-coffee-may-make-lipitor-less-effective\"><span style=\"font-weight: 400;\">9. Your morning coffee may make Lipitor less effective<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A <\/span><a href=\"https:\/\/link.springer.com\/article\/10.1007%2Fs10557-008-6105-z\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">study on rats<\/span><\/a><span style=\"font-weight: 400;\"> suggests caffeinated coffee may reduce one of the cardioprotective benefits of atorvastatin. That\u2019s because caffeine is a nonspecific adenosine receptor blocker. Adenosine receptor activation is essential for Lipitor to work. Meaning, your daily joe may make it less effective. Talk with your healthcare provider about your caffeine consumption.<\/span><\/p>\n<h3 id=\"10-lipitor-may-be-good-for-your-dental-health\"><span style=\"font-weight: 400;\">10. Lipitor may be good for your dental health<\/span><\/h3>\n<p><a href=\"https:\/\/translational-medicine.biomedcentral.com\/articles\/10.1186\/s12967-020-02326-8\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Research<\/span><\/a><span style=\"font-weight: 400;\"> suggests that statins like Lipitor can have several beneficial effects for your mouth. They can improve bone health to keep teeth strong, prevent tissue degeneration that can lead to periodontal disease, and even have protective effects against oral cancers. Some dentists are starting to consider statins therapeutic for dental and oral health.<\/span><\/p>\n<h3 id=\"11-you-may-need-lipitor-even-if-your-cholesterol-is-normal\"><span style=\"font-weight: 400;\">11. You may need Lipitor even if your cholesterol is normal<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Lipitor is usually thought of as a cholesterol-lowering medication. However, even if your cholesterol levels are in the normal range, your healthcare provider may prescribe it. Why?\u00a0<\/span><span style=\"font-weight: 400;\"><span style=\"box-sizing: border-box; margin: 0px; padding: 0px;\">It can help\u00a0<a href=\"https:\/\/www.hopkinsmedicine.org\/health\/wellness-and-prevention\/how-statin-drugs-protect-the-heart\" target=\"_blank\" rel=\"noopener\">decrease the risk of cardiovascular disease and events<\/a> (like heart attacks) for high-risk groups.<\/span>\u00a0For example, if you\u2019re prone to blood clots or if you already have arterial plaque buildup.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Additionally, if you\u2019re taking Lipitor to manage hyperlipidemia, you need to keep taking it once your levels return to normal. If you stop taking statins, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/effects-of-high-cholesterol\/\"><span style=\"font-weight: 400;\">cholesterol levels<\/span><\/a><span style=\"font-weight: 400;\"> will creep back up within two months.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/cholesterol-test\/\"><b>Understanding cholesterol tests<\/b><\/a><\/p>\n<h3 id=\"12-there-are-ways-to-save-on-lipitor\"><span style=\"font-weight: 400;\">12. There are ways to save on Lipitor<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">On average, brand-name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lipitor\"><span style=\"font-weight: 400;\">Lipitor costs about<\/span><\/a><span style=\"font-weight: 400;\"> $433.39 for 30, 10 mg tablets. A generic <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/atorvastatin-calcium\"><span style=\"font-weight: 400;\">form of atorvastatin<\/span><\/a><span style=\"font-weight: 400;\"> is available and has been <\/span><a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.116.003350\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">shown to be as effective<\/span><\/a><span style=\"font-weight: 400;\"> as Lipitor. That\u2019s good news beca<a href=\"https:\/\/www.singlecare.com\/blog\/atorvastatin-without-insurance\/\">use generic atorvastatin is much less expensive<\/a>.<\/span><\/p>\n<h3 id=\"13-lipitor-is-not-interchangeable-with-other-statins\"><span style=\"font-weight: 400;\">13. Lipitor is not interchangeable with other statins<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">While they belong to the same family of drugs, statins are not all the same. They vary in areas such as chemical properties, dosage, potency, efficacy, safety, and side effects.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cDepending on what your healthcare provider recommends, you might need low, moderate, or high intensity statins,\u201d says Dr. Hennis. \u201cFor example, high intensity statins include <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/crestor-vs-lipitor\/\"><span style=\"font-weight: 400;\">Lipitor 40 mg-80 mg and Crestor 20-40 mg<\/span><\/a><span style=\"font-weight: 400;\">. One is not better than the other; the dose and the medication type are what are important.\u201d\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lipitor is a good choice for many people, but it\u2019s important to make sure it is the right choice for you. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/atorvastatin-vs-simvastatin\/\"><span style=\"font-weight: 400;\">Which statin to use<\/span><\/a><span style=\"font-weight: 400;\"> depends on a number of factors, and should be discussed with your healthcare provider and pharmacist.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A healthy diet and exercise are important for heart health\u2014partially because they help keep cholesterol levels in check. But, for some people, lifestyle changes aren\u2019t enough. Medication may be necessary to avoid heart disease. Statins are among the most common medications prescribed to lower cholesterol. This class of medication helps to decrease low-density lipoprotein (LDL) [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":48247,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,737,11278],"coauthors":[8622],"class_list":["post-48243","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-heart-health","tag-singlecare-for-seniors","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>13 Lipitor facts you should know<\/title>\n<meta name=\"description\" content=\"Lipitor is the most prescribed statin. Did you know that it can reduce LDL cholesterol by up to 60%? 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