{"id":48467,"date":"2022-02-02T11:54:49","date_gmt":"2022-02-02T16:54:49","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=48467"},"modified":"2025-11-26T19:07:59","modified_gmt":"2025-11-27T00:07:59","slug":"xarelto-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/xarelto-alternatives\/","title":{"rendered":"Xarelto alternatives: What can I take instead of Xarelto?"},"content":{"rendered":"

Xarelto<\/span><\/a> is a brand-name prescription drug that contains the active ingredient rivaroxaban. Xarelto is a direct oral anticoag<\/span>ulant (DOAC)\u2014a newer blood thinner\u2014used to treat and prevent blood clots in the legs (<\/span>deep vein thrombosis or DVT<\/span><\/a>) and lungs (pulmonary embolism or PE). It\u2019s also used to prevent stroke in people with <\/span>atrial fibrillation (AFib)<\/span><\/a> not caused by a heart valve problem, and to reduce the risk of major cardiovascular events in people with coronary artery disease (CAD) or peripheral artery disease (PAD). <\/span>Xarelto is also used <\/span>to reduce the risk of DVT<\/span> after hip or knee replacement surgery. In some cases, you may be interested in seeking an alternative to Xarelto\u2014whether due to price, side effects, or other reasons. The good news is that there are various options you can discuss with your healthcare provider.<\/span><\/p>\n

What can I take instead of Xarelto?\u00a0<\/span><\/h2>\n

There are various anticoagulant drugs similar to Xarelto. These medications may have different FDA-approved uses, possible side effects, and dosages, which are highlighted in the table below. Another option may be more suitable for someone looking for a Xarelto alternative.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Compare Xarelto alternatives<\/span><\/th>\n<\/tr>\n<\/thead>\n
Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Xarelto<\/span><\/a> (rivaroxaban)<\/span><\/td>\n$808 for 60, 2.5 mg tablets<\/span><\/td>\n$71 for 60, 2.5 mg tablets of generic rivaroxaban at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Eliquis (apixaban)<\/span><\/td>\n$816 for 60, 5 mg tablets<\/span><\/td>\n$488 for 60, 5 mg tablets of brand-name Eliquis at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Warfarin<\/span><\/td>\n$29 for 30, 5 mg tablets<\/span><\/td>\n$4 for 30, 5 mg tablets of generic warfarin at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Pradaxa (dabigatran)<\/span><\/td>\n$494 for 60, 150 mg capsules<\/span><\/td>\n$51 for 60, 150 mg capsules of generic dabigatran at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Plavix (<\/span>clopidogrel<\/span><\/a>)<\/span><\/td>\n$641 for 30, 75 mg tablets<\/span><\/td>\n$5 for 30, 75 mg tablets of generic clopidogrel at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Brilinta <\/span>(ticagrelor)<\/span><\/td>\n$627 for 60, 90 mg tablets<\/span><\/td>\n$31 for 60, 90 mg tablets of generic ticagrelor at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Effient (prasugrel)<\/span><\/td>\n$733 for 30, 10 mg tablets<\/span><\/td>\n$20 for 30, 10 mg tablets of generic prasugrel at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Savaysa (edoxaban)<\/span><\/td>\n$539 for 30, 60 mg tablets<\/span><\/td>\n$452 for 30, 60 mg tablets of brand-name Savaysa at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Arixtra <\/span>(fondaparinux)<\/span><\/td>\n$190 for 10, 2.5 mg syringes<\/span><\/td>\n$59 for 10, 2.5 mg syringes of generic <\/span>fondaparinux at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Lovenox (enoxaparin)<\/span><\/td>\n$53 for 1, 10 mL of 40 mg\/0.4 mL syringe<\/span><\/td>\n$43 for 1, 10 mL of 40 mg\/0.4 mL syringe at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of November 26, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under \u201cSavings options\u201d to see the latest drug prices.<\/span><\/i><\/small><\/p>\n

Top 6 Xarelto alternatives<\/span><\/h2>\n

The following are some of the most common alternatives to Xarelto.<\/span><\/p>\n

1. Generic Xarelto (rivaroxaban 2.5 mg dose only)<\/span><\/h3>\n

If you are interested in Xarelto generic alternatives, it\u2019s important to note that not all of the available brand-name Xarelto doses<\/a> have a corresponding generic. Brand-name Xarelto is available in 2.5 mg, 5 mg, 10 mg, and 20 mg tablets, as well as a liquid form. However, only the <\/span>2.5 mg tablet is available in generic form<\/span><\/a>. If cost is the reason you are looking for an Xarelto substitute, and you are taking the 2.5 mg dose, filling your prescription for generic Xarelto might be your best option. The 2.5 mg dose is FDA approved (along with aspirin) to prevent stroke and other cardiovascular events in people with coronary artery disease (CAD) or peripheral artery disease (PAD). So, this switch will only apply to certain patients who are taking Xarelto for CAD or PAD.\u00a0<\/span><\/p>\n\t\t

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Save up to 80% on Xarelto with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tXarelto 2.5 mg (60 Tablet)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"CVS\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$47.91\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Publix\"\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$75.35\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Xarelto prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

2. Eliquis<\/span><\/h3>\n

Eliquis<\/span><\/a> (apixaban) is a direct oral anticoagulant medication that works in the same way as Xarelto by blocking a protein in the body called factor Xa, thereby reducing blood clotting. This newer drug is one of the most popular anticoagulants available to lower the risk of DVT, PE, and stroke in Afib patients. Like all blood thinners, <\/span>Eliquis<\/span><\/a> can cause <\/span>bleeding side effects<\/span><\/a> such as nosebleeds and bruising. An antidote to reverse major bleeding is available for both Eliquis and Xarelto. The <\/span>standard dosage for Eliquis<\/span><\/a> is 2.5 mg or 5 mg twice daily, depending on the indication.<\/span><\/p>\n

RELATED: <\/b>Eliquis vs. Xarelto<\/b><\/a><\/p>\n

3. Warfarin<\/span><\/h3>\n

Warfarin<\/span><\/a> (brand names: Coumadin and Jantoven) is the oldest and one of the most commonly used anticoagulants. <\/span>Warfarin<\/span><\/a> works by blocking the action of vitamin K to stop the blood clotting process. Xarelto and warfarin are both similarly effective at preventing DVT, PE, and stroke, but warfarin requires additional monitoring to measure how well the drug is working. <\/span>Individuals taking warfarin must undergo regular blood tests to monitor the international normalized ratio (INR), which represents how quickly the blood clots. Based on the INR value, <\/span>the dose of warfarin may be changed. <\/span>There <\/span>are also many medications and foods that interact with warfarin.\u00a0<\/span><\/p>\n

RELATED: <\/b>Eliquis vs. warfarin<\/b><\/a><\/p>\n

4. Pradaxa<\/span><\/h3>\n

Pradaxa<\/span><\/a> (dabigatran) is another anticoagulant like Xarelto, but it works by blocking a different blood-clotting protein called thrombin. Pradaxa and Xarelto are prescribed for similar reasons, and <\/span>studies<\/span><\/a> have found these two drugs to be similarly effective in preventing stroke in Afib patients. However, Pradaxa was associated with a lower major bleeding risk compared to Xarelto. Other notable side effects of Pradaxa include stomach pain and heartburn. The standard dosage of Pradaxa is 150 mg twice daily.\u00a0<\/span><\/p>\n

5. Plavix<\/span><\/h3>\n

Plavix<\/span><\/a> (clopidogrel) is an antiplatelet drug that helps prevent blood clots by preventing platelets from sticking together. Plavix and Xarelto are both used to prevent heart attack and stroke in individuals with heart and vascular diseases, but they work in different ways. <\/span>Side effects of Plavix<\/span><\/a> and Xarelto are similar and include increased bleeding, itching, and stomach pain. For heart disease, Plavix is usually taken along with aspirin, where Plavix is given at a dosage of 75 mg once daily.<\/span><\/p>\n

RELATED: <\/b>Plavix vs. Brilinta<\/b><\/a><\/p>\n

6. Brilinta<\/span><\/h3>\n

Brilinta<\/span><\/a> (ticagrelor) is another antiplatelet medication that is approved by the Food and Drug Administration (FDA) for use in heart disease patients at increased risk of stroke and heart attack. Brilinta and Xarelto both increase the likelihood of bleeding, but Brilinta has an <\/span>additional side effect<\/span><\/a> of shortness of breath, which occurs in about <\/span>14%<\/span><\/a> of people taking the medication. Brilinta is usually prescribed at a <\/span>dosage<\/span><\/a> of 60 mg or 90 mg twice daily, together with low-dose aspirin.<\/span><\/p>\n

RELATED: <\/b>Do Brilinta and caffeine mix?<\/b><\/a><\/p>\n

Natural alternatives to Xarelto<\/span><\/h2>\n

In addition to prescription anticoagulants, there are also certain foods and vitamins that naturally have blood thinning properties. Taking these over-the-counter nutritional supplements along with maintaining a healthy lifestyle may help reduce the risk of blood clots and cardiovascular disease, but they are not a substitute for medications prescribed by your doctor. It is important to speak with a healthcare professional before trying these remedies, as they may interact with some prescription drugs.<\/span><\/p>\n

Natural blood thinners include the following foods and supplements:<\/span><\/p>\n