{"id":49217,"date":"2022-02-20T19:38:42","date_gmt":"2022-02-21T00:38:42","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=49217"},"modified":"2025-04-11T13:01:42","modified_gmt":"2025-04-11T17:01:42","slug":"farxiga-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/farxiga-alternatives\/","title":{"rendered":"Farxiga alternatives: What can I take instead of Farxiga?"},"content":{"rendered":"

Farxiga<\/span><\/a> is a brand-name medication that contains the active ingredient dapagliflozin, one of the sodium-glucose cotransporter 2 (SGLT2) inhibitors. It\u2019s manufactured by AstraZeneca\u2014 although a <\/span>generic has recently become available<\/span><\/a>. Farxiga is used for <\/span>blood glucose<\/span><\/a> (sugar) control in people with <\/span>Type 2 diabetes mellitus<\/span><\/a>. It works by increasing urinary glucose, so more sugar is eliminated from the body through the urine. Much attention has been paid to the <\/span>SGLT2 inhibitors<\/span><\/a> in recent years as cardiac and renal (kidney) benefits have come to light. Based on its advantages for heart failure treatment and the setting of renal impairment, Farxiga and other members of the class are increasingly being chosen for Type 2 diabetes treatment. Their once-a-day oral dosing is also attractive for some in comparison to injectable drugs. For those who cannot take Farxiga, there are many alternatives available.\u00a0<\/span><\/p>\n

RELATED:<\/b> What is Farxiga used for?<\/b><\/a><\/p>\n

What can I take in place of Farxiga?<\/span><\/h2>\n

If you are interested in switching to a different medicine, there are other options available, depending on the reason for use. It\u2019s important to always discuss medication changes with a healthcare professional before stopping Farxiga. A healthcare provider or pharmacist will be able to provide you with the right prescribing information and medication guides to inform your decision. These Farxiga alternatives may have different uses, side effects, and dosages, which are highlighted in the table below.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare Farxiga alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/td>\nUses<\/td>\nCommon side effects<\/td>\nDosage<\/td>\nGet coupon<\/td>\n<\/tr>\n
Farxiga (dapagliflozin)<\/span><\/td>\n\n
    \n
  • Chronic kidney Disease<\/span><\/li>\n
  • Heart failure<\/span><\/li>\n
  • Type 2 diabetes with heart disease or risk factors for heart disease<\/span><\/li>\n
  • Type 2 diabetes\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Vaginal yeast infection<\/span><\/li>\n
  • Yeast infection of the penis<\/span><\/li>\n
  • Stuffy or runny nose<\/span><\/li>\n
  • Sore throat<\/span><\/li>\n
  • Urinating more frequently and\/or in larger amounts<\/span><\/li>\n<\/ul>\n<\/td>\n
5\u201310 mg once daily<\/span><\/td>\nGet Farxiga coupons<\/span><\/a><\/td>\n<\/tr>\n
Januvia (sitagliptin)<\/strong><\/td>\n\n
    \n
  • Type 2 diabetes\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Upper respiratory infection<\/span><\/li>\n
  • Stuffy or runny nose<\/span><\/li>\n
  • Sore throat<\/span><\/li>\n
  • Headache\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
100 mg once daily<\/span><\/td>\nGet Januvia coupons<\/span><\/a><\/td>\n<\/tr>\n
Jardiance (empagliflozin)<\/strong><\/td>\n\n
    \n
  • Heart failure<\/span><\/li>\n
  • Chronic kidney disease<\/span><\/li>\n
  • Type 2 diabetes with cardiovascular disease<\/span><\/li>\n
  • Type 2 diabetes<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Yeast infections<\/span><\/li>\n
  • UTI<\/span><\/li>\n<\/ul>\n<\/td>\n
10\u201325 mg once daily<\/span><\/td>\nGet Jardiance coupons<\/span><\/a><\/td>\n<\/tr>\n
Metformin<\/strong><\/td>\n\n
    \n
  • Type 2 diabetes\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Nausea\u00a0<\/span><\/li>\n
  • Vomiting<\/span><\/li>\n
  • Diarrhea<\/span><\/li>\n
  • Gas<\/span><\/li>\n
  • Stomach discomfort<\/span><\/li>\n
  • Indigestion<\/span><\/li>\n
  • Weakness\u00a0<\/span><\/li>\n
  • Headache\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
500\u20131,000 mg twice daily<\/span><\/td>\nGet metformin coupons<\/span><\/a><\/td>\n<\/tr>\n
Mounjaro (tirzepatide)<\/strong><\/td>\n\n
    \n
  • Type 2 diabetes<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Nausea<\/span><\/li>\n
  • Vomiting\u00a0<\/span><\/li>\n
  • Diarrhea<\/span><\/li>\n
  • Stomach pain<\/span><\/li>\n
  • Constipation<\/span><\/li>\n
  • Indigestion\u00a0<\/span><\/li>\n
  • Decreased appetite<\/span><\/li>\n<\/ul>\n<\/td>\n
Starting dose is 2.5 mg injected once per week; the healthcare provider will instruct how to gradually increase the dose<\/span><\/td>\nGet Mounjaro coupons<\/span><\/a><\/td>\n<\/tr>\n
Ozempic (semaglutide)<\/strong><\/td>\n\n
    \n
  • Type 2 diabetes<\/span><\/li>\n
  • Cardiovascular risk reduction<\/span><\/li>\n
  • Kidney disease<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Nausea<\/span><\/li>\n
  • Vomiting\u00a0<\/span><\/li>\n
  • Diarrhea<\/span><\/li>\n
  • Stomach pain<\/span><\/li>\n
  • Constipation<\/span><\/li>\n<\/ul>\n<\/td>\n
Starting dose is 0.25 mg injected once per week; the healthcare provider will instruct how to gradually increase the dose<\/span><\/td>\nGet Ozempic coupons<\/span><\/a><\/td>\n<\/tr>\n
Rybelsus (semaglutide)<\/strong><\/td>\n\n
    \n
  • Type 2 diabetes\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Nausea<\/span><\/li>\n
  • Vomiting\u00a0<\/span><\/li>\n
  • Diarrhea<\/span><\/li>\n
  • Decreased appetite<\/span><\/li>\n
  • Stomach pain<\/span><\/li>\n
  • Constipation<\/span><\/li>\n<\/ul>\n<\/td>\n
7\u201314 mg once daily<\/span><\/td>\nGet Rybelsus coupons<\/span><\/a><\/td>\n<\/tr>\n
Victoza (liraglutide)<\/strong><\/td>\n\n
    \n
  • Type 2 diabetes<\/span><\/li>\n
  • Cardiovascular risk reduction<\/span><\/li>\n<\/ul>\n<\/td>\n
\n
    \n
  • Nausea<\/span><\/li>\n
  • Vomiting\u00a0<\/span><\/li>\n
  • Diarrhea<\/span><\/li>\n
  • Decreased appetite<\/span><\/li>\n
  • Indigestion<\/span><\/li>\n
  • Constipation\u00a0<\/span><\/li>\n<\/ul>\n<\/td>\n
Starting dose is 0.6 mg subcutaneous injection once daily; the healthcare provider will instruct how to gradually increase the dose<\/span><\/td>\nGet Victoza coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Other alternatives to Farxiga<\/span><\/h3>\n

Additionally, there are many other alternatives to Farxiga, including oral and injectable medications. Injectable options include either insulin or other non-insulin drugs, such as GLP-1s (like Ozempic). There are also many combination drugs\u2014drugs that contain more than one ingredient. You can find out more about Farxiga alternatives from your healthcare provider.\u00a0<\/span><\/p>\n\t\t

\n\t\t\t

Save up to 80% on Farxiga with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tFarxiga 10 mg (30 tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23663 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Food\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$40.70\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"CVS\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$207.43\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Farxiga prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

Top 5 Farxiga alternatives<\/span><\/h2>\n

Below are some common alternatives to Farxiga. When used for Type 2 diabetes, healthcare providers typically recommend incorporating lifestyle changes like diet and exercise, along with weight loss, if needed, in combination with medication.<\/span><\/p>\n

1. Jardiance<\/span><\/h3>\n

Like Farxiga, <\/span>Jardiance<\/span><\/a> is an SGLT2 inhibitor. Jardiance is a brand-name drug (with no generic available) and has similar side effects to Farxiga. Farxiga and Jardiance are commonly associated with <\/span>genital yeast infections<\/span><\/a> and <\/span>urinary tract infections<\/span><\/a> (UTIs).\u00a0<\/span><\/p>\n

Both have a diuretic effect by eliminating fluid from the body while they reduce sugar. Consequently, they can be helpful in the setting of <\/span>congestive heart failure<\/span><\/a> with a reduced cardiac ejection fraction (lower percentage of blood squeezed out of the pumping chambers with a heartbeat) and can help to lower blood pressure.\u00a0<\/span><\/p>\n

Conversely, <\/span>Jardiance was shown to reduce the risk of cardiovascular morbidity and mortality<\/span><\/a> in individuals with Type 2 diabetes and high cardiovascular risk, so it may be a better alternative to Farxiga in those with high cardiovascular risk.<\/span><\/p>\n

Based on a clinical trial<\/span><\/a>, Farxiga has an additional indication from the Food and Drug Administration (FDA) for reducing the risk of kidney problems and kidney disease progression in chronic renal disease.\u00a0<\/span><\/p>\n

RELATED: <\/b>Jardiance side effects<\/b><\/a> | <\/b>Jardiance dosage<\/b><\/a><\/p>\n

2. Mounjaro<\/span><\/h3>\n

Mounjaro is a brand-name once-weekly injectable medicine. It contains the active ingredient tirzepatide. Mounjaro is classified as a GIP\/GLP-1 receptor agonist. It is FDA-approved for Type 2 diabetes, and is often prescribed <\/span>off-label<\/span><\/a> (for a non-FDA-approved use) for weight loss and long-term weight management. The starting dose is 2.5 mg, injected once weekly, and the healthcare provider will instruct how to gradually increase the dose.<\/span><\/p>\n

Common side effects of Mounjaro are mostly related to the stomach and intestines and include nausea, vomiting, diarrhea or constipation, indigestion, stomach pain, and decreased appetite.<\/span><\/p>\n

Mounjaro has a <\/span>black box warning<\/span><\/a>, the most serious warning required by the FDA. The active ingredient in Mounjaro, tirzepatide, has caused thyroid tumors in animal studies. It is not known whether this risk applies to humans. Because of this risk, people with a personal or family history of medullary thyroid carcinoma (MTC)\u2014or those with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use Mounjaro.\u00a0<\/span><\/p>\n

Tirzepatide is also available as another FDA-approved drug called <\/span>Zepbound<\/span><\/a>, which is a once-weekly injectable drug used for weight loss and <\/span>obstructive sleep apnea<\/span><\/a>.\u00a0<\/span><\/p>\n

Compounded tirzepatide<\/span><\/a> products are not FDA-approved.<\/span><\/p>\n

RELATED: <\/b>Mounjaro side effects<\/b><\/a> | <\/b>Mounjaro dosage<\/b><\/a><\/p>\n

3. Metformin<\/span><\/h3>\n

The <\/span>preferred initial drug<\/span><\/a> and long-term maintenance drug for Type 2 diabetes mellitus is metformin, the one member of the <\/span>biguanide class<\/span><\/a>. <\/span>Metformin<\/span><\/a> helps prevent weight gain and hypoglycemia (low blood sugar), and <\/span>it can slow the progression of diabetes<\/span><\/a>.\u00a0<\/span><\/p>\n

Metformin, a generic medication, has a much lower cost than Farxiga. Contraindications to metformin, such as advanced kidney disease, and gastrointestinal adverse effects, like diarrhea, are limiting factors. The extended-release formulation of metformin is tried at times to lessen gastrointestinal side effects, like diarrhea.<\/span><\/p>\n

RELATED: <\/b>Metformin side effects<\/b><\/a> | <\/b>Metformin vs. metformin ER<\/b><\/a><\/p>\n

4. Januvia<\/span><\/h3>\n

While it is an expensive brand-name medication, <\/span>Januvia<\/span><\/a> does have some advantages over Farxiga. Januvia and other dipeptidyl peptidase-4 (DPP-4) inhibitors, such as Tradjenta, Onglyza, and Nesina, avoid side effects of the genitals and urinary organs as well as orthostatic hypotension (low blood pressure upon standing) that can affect Farxiga users. However, Januvia does not have FDA approvals for cardiac or kidney protection.<\/span><\/p>\n

RELATED: <\/b>Januvia side effects<\/b><\/a> | <\/b>Januvia dosage<\/b><\/a><\/p>\n

5. Ozempic<\/span><\/h3>\n

Ozempic (semaglutide) is a <\/span>GLP-1 receptor agonist<\/span><\/a>. The starting dose is 0.25 mg, injected once weekly, and the healthcare provider will instruct how to gradually increase the dose.\u00a0<\/span><\/p>\n

Ozempic is FDA-approved for Type 2 diabetes, cardiovascular risk reduction, and kidney disease. It is frequently prescribed off-label for weight loss.\u00a0<\/span><\/p>\n

Common side effects of Ozempic include nausea, vomiting, diarrhea, stomach pain, and constipation.\u00a0<\/span><\/p>\n

Like Mounjaro, Ozempic has a black box warning and should not be used in those with a personal or family history of MTC or people with MEN 2.\u00a0<\/span><\/p>\n

Semaglutide is also available as two other FDA-approved drugs:<\/span><\/p>\n