{"id":49475,"date":"2022-03-07T08:55:57","date_gmt":"2022-03-07T13:55:57","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=49475"},"modified":"2026-01-30T15:05:03","modified_gmt":"2026-01-30T20:05:03","slug":"januvia-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/januvia-alternatives\/","title":{"rendered":"Januvia alternatives: What can I take instead of Januvia?"},"content":{"rendered":"

Januvia<\/span><\/a> (sitagliptin)<\/span> is a brand-name medication made by the pharmaceutical company <\/span>Merck Sharp & Dohme. This prescription drug is part of a class of medicines called <\/span>dipeptidyl peptidase-4 (DPP-4) inhibitors<\/span><\/a>. <\/span>Januvia<\/span><\/a> is approved by the United States Food and Drug Administration (FDA) to improve <\/span>blood sugar<\/span><\/a> control in adults with <\/span>Type 2 diabetes mellitus<\/span><\/a>. In some cases, the price of Januvia may be high, even with insurance coverage. Some people cannot take Januvia, or may experience unpleasant <\/span>side effects<\/span><\/a>. If you are thinking about exploring alternatives to Januvia, there are many other drugs you can discuss with your healthcare provider.<\/span><\/p>\n\t\t

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Save up to 80% on Januvia with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tJanuvia 100 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$324.74\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$324.74\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Januvia prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

What can I take instead of Januvia<\/span>?<\/span><\/h2>\n

In the table below, we look at <\/span>Januvia<\/span> and common alternatives to <\/span>Januvia<\/span>. All drugs listed are prescription <\/span>diabetes medications<\/span> approved by the <\/span>FDA<\/span>.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Compare Januvia alternatives<\/span><\/th>\n<\/tr>\n<\/thead>\n
Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Januvia<\/span><\/a> (<\/span>sitagliptin<\/span>)<\/span><\/td>\n$709 for 30, 100 mg tablets<\/span><\/td>\n$286 for 30, 100 mg tablets of brand-name Januvia at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Actos<\/a> (pioglitazone)<\/span><\/td>\n$2,111 for 90, 30 mg tablets<\/span><\/td>\n$27 for 90, 30 mg tablets of generic pioglitazone at Publix<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Farxiga<\/span><\/a> (dapagliflozin)<\/span><\/td>\n$802 for 30, 10 mg tablets<\/span><\/td>\n$405 for 30, 10 mg tablets of generic dapagliflozin at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Amaryl (<\/span>glimepiride<\/span><\/a>)<\/span><\/td>\n$23 for 30, 2 mg tablets<\/span><\/td>\n$6 for 30, 2 mg tablets of generic glimepiride at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Glipizide<\/span><\/a><\/td>\n$46 for 180, 10 mg tablets<\/span><\/td>\n$17 for 180, 10 mg tablets of generic glipizide at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Metformin<\/span><\/a>\u00a0<\/span><\/td>\n$131 for 60, 500 mg tablets<\/span><\/td>\n$5 for 60, 500 mg tablets of generic metformin at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Invokana (canagliflozin)<\/span><\/td>\n$821 for 30, 300 mg tablets<\/span><\/td>\n$587 for 30, 300 mg tablets of brand-name Invokana at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Janumet<\/span><\/a> (<\/span>sitagliptin<\/span> and <\/span>metformin<\/span>)<\/span><\/td>\n$685 for 60, 50\/1,000 mg tablets<\/span><\/td>\n$325 for 60, 50\/1,000 mg tablets of brand-name Janumet at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Jardiance<\/span><\/a> (empagliflozin)<\/span><\/td>\n$848 for 30, 25 mg tablets<\/span><\/td>\n$255 for 30, 25 mg tablets of brand-name Jardiance at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Mounjaro<\/span><\/a> (tirzepatide)<\/span><\/td>\n$1,504 for 4, 0.5 mL of 5 mg\/0.5mL pens<\/span><\/td>\n$895 for <\/span>4, 0.5 mL of 5 mg\/0.5 mL pens of brand-name Mounjaro at Publix<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Nesina (alogliptin)<\/span><\/td>\n$152 for 14, 25 mg tablets<\/span><\/td>\n$91 for 14, 25 mg tablets of generic alogliptin at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Ozempic<\/span><\/a> (semaglutide)<\/span><\/td>\n$1,399 for 1, 3 mL of 2 mg\/3mL pen<\/span><\/td>\n$844 for 1, 3 mL of 2 mg\/3 mL pen of brand-name Ozempic at Publix<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Rybelsus<\/span><\/a> (semaglutide)<\/span><\/td>\n$1,367 for 30, 14 mg tablets<\/span><\/td>\n$903 for 30, 14 mg tablets of brand-name Rybelsus at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Saxagliptin<\/span><\/td>\n$468 for 30, 5 mg tablets\u00a0<\/span><\/td>\n$74 for 30, 5 mg tablets of generic saxagliptin at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Tradjenta<\/span> (<\/span>linagliptin<\/span>)<\/span><\/td>\n$725 for 30, 5 mg tablets<\/span><\/td>\n$516 for 30, 5 mg tablets of brand-name Tradjenta at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Trulicity<\/span><\/a> (dulaglutide)<\/span><\/td>\n$1,392 for 4, 0.5 mL of 1.5 mg\/0.5 mL pens<\/span><\/td>\n$825 for 4, 0.5 mL of 1.5 mg\/0.5 mL pens of brand-name Trulicity at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Victoza<\/span><\/a> (liraglutide)<\/span><\/td>\n$1,438 for 3, 3 mL of 18 mg\/3mL pens<\/span><\/td>\n$221 for 3, 3 mL of 18 mg\/3 mL pens of generic liraglutide at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of Jan. 30, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.<\/em><\/small><\/small><\/p>\n

Top 5 Januvia alternatives<\/span><\/h2>\n

1. Tradjenta<\/span><\/h3>\n

Like <\/span>Januvia<\/span>, <\/span>Tradjenta<\/span> (<\/span>linagliptin<\/span>) is in the <\/span>DPP-4 inhibitor<\/span> class of <\/span>diabetes drugs<\/span>. If the reason you are looking for a <\/span>Januvia<\/span> alternative is due to <\/span>side effects<\/span> or an <\/span>allergic reaction<\/span>, then <\/span>Tradjenta<\/span> would not be a good alternative, because it is very similar to <\/span>Januvia,<\/span> and you would likely have the same reaction. <\/span>Tradjenta<\/span> is used along with diet and exercise to improve <\/span>blood sugar<\/span> control in adults with Type 2 diabetes. It is not approved for use in children. The typical dose of <\/span>Tradjenta<\/span> is 5 mg by mouth daily.\u00a0<\/span><\/p>\n

The most <\/span>common side effects<\/span> are cough, cold, <\/span>low blood sugar<\/span>, and diarrhea. Serious <\/span>side effects<\/span> can include heart or kidney failure, <\/span>pancreatitis<\/span>, <\/span>joint pain<\/span><\/a> (which may be severe), or a severe skin or <\/span>allergic reaction<\/span>. <\/span>Tradjenta<\/span> should be used with caution in patients at risk of <\/span>heart failure<\/span> or <\/span>pancreatitis<\/span>.\u00a0<\/span><\/p>\n

2. Metformin<\/span><\/h3>\n

Metformin<\/span> is in a <\/span>class of drugs<\/span> called <\/span>biguanides<\/span><\/a>. <\/span>Metformin<\/span> is a <\/span>generic drug<\/span><\/a>. The <\/span>brand name<\/span> is called <\/span>Glucophage, but Glucophage is no longer available in the U.S<\/span>. <\/span>Metformin<\/span> works by<\/span><\/a> decreasing the amount of sugar you absorb from food. It also decreases <\/span>glucose<\/span> (sugar) production in the liver and increases the body\u2019s response to insulin (insulin helps control <\/span>blood sugar<\/span>). <\/span>Metformin<\/span> i<\/span>s used along with diet and exercise to improve <\/span>blood sugar<\/span> control in adults and children 10 years and older with Type 2 diabetes. After slowly increasing the dose over several weeks, a typical daily dosage of <\/span>metformin<\/span> for adults is 850 mg or 1,000 mg twice daily with meals. Metformin is inexpensive, effective, and is <\/span>often a first choice<\/span><\/a> for blood sugar control.<\/span><\/p>\n

The most <\/span>common <\/span>side effects<\/span> of <\/span>metformin<\/span><\/a> are stomach-related and can include nausea, vomiting, diarrhea, gas, stomach discomfort, and indigestion. Patients taking <\/span>metformin<\/span> should be aware of a rare but serious <\/span>side effect<\/span> called <\/span>lactic acidosis<\/span>. <\/span>Lactic acidosis<\/span> is an emergency, and patients having symptoms should seek emergency treatment in the hospital right away. Symptoms may include feeling unwell, muscle pain, difficulty breathing, stomach pain, and sleepiness.<\/span><\/p>\n

3. Jardiance<\/span><\/h3>\n

Jardiance<\/span><\/a> (empagliflozin) is in a drug class called <\/span>sodium <\/span>glucose<\/span> co-transporter 2 (SGLT2) <\/span>inhibitors<\/span>. <\/span>SGLT2 <\/span>inhibitors<\/span><\/a> work by helping the kidneys remove sugar from the body through the urine. Jardiance is approved for the following indications:<\/span><\/p>\n