{"id":50254,"date":"2022-04-02T16:47:17","date_gmt":"2022-04-02T20:47:17","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=50254"},"modified":"2025-12-11T09:15:35","modified_gmt":"2025-12-11T14:15:35","slug":"entresto-without-insurance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/entresto-without-insurance\/","title":{"rendered":"How much is Entresto without insurance?"},"content":{"rendered":"

Entresto is a brand-name prescription drug used to reduce the risk of serious cardiovascular events and hospitalization in adults and children with <\/span>chronic heart failure<\/span><\/a>. A combination of two drugs, sacubitril and valsartan, Entresto relaxes blood vessels and reduces blood pressure, leading to reduced strain on the heart and slowing the progression of heart failure. Entresto is a higher-priced, brand-name medication, but people without insurance have a number of options for saving money.<\/span><\/p>\n

How much does Entresto cost without insurance?<\/span><\/h2>\n

The average retail price for Entresto without insurance is $969 for 60, 24\/26 mg tablets. <\/span>Since Entresto tablets are taken twice a day<\/span><\/a>, 60 tablets are enough medicine for a 30-day supply. That means each tablet costs about $16. Each day\u2019s treatment costs on average $32. Heart failure medications like Entresto are prescribed for months or years, so people without insurance coverage should expect to pay over $11,000 a year for Entresto.<\/span><\/p>\n

Cost is a valid reason to seek Entresto alternatives. Other common reasons for switching medications are troublesome or serious side effects, if you have a <\/span>contraindication<\/span><\/a> and cannot take Entresto (such as kidney problems, allergic reactions, <\/span>pregnancy, or breastfeeding<\/span><\/a>), or if you take a <\/span>drug that interacts<\/span><\/a> with Entresto.<\/span><\/p>\n

RELATED: <\/b>Side effects of Entresto<\/b><\/a><\/p>\n

While one of the drugs in Entresto, <\/span>valsartan<\/span><\/a>, is widely available in generic versions, sacubitril is only found in Entresto. Entresto is a one-of-a-kind drug and the only member of its class (angiotensin receptor-neprilysin inhibitors or ARNIs).\u00a0<\/span><\/p>\n

There are no over-the-counter drugs or supplements that can effectively treat heart failure in place of prescription medications. And although there are no alternatives available within the same drug class as sacubitril, other FDA-approved medications can treat heart failure. Some of them are available in more affordable, generic versions. These include drug classes such as <\/span>diuretics<\/span><\/a>, <\/span>ACE inhibitors<\/span><\/a>, <\/span>beta blockers<\/span><\/a>, sodium-glucose cotransporter 2 (SGLT2) inhibitors, and <\/span>angiotensin II receptor blockers (ARBs)<\/span><\/a>. Before stopping Entresto, consult your healthcare provider about the following heart failure medications and whether they could work for you.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
Drug name<\/b><\/td>\nPrice without insurance\u00a0<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Entresto<\/span><\/a> (<\/span>sacubitril\/valsartan<\/span><\/a>)<\/span><\/td>\n$969 per 60, 24\/26 mg tablets<\/span><\/td>\n$50 per 60, 24\/26 mg tablets of generic Entresto at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Diovan<\/span><\/a> (valsartan)<\/span><\/a><\/td>\n$1,136 per 90, 160 mg tablets<\/span><\/td>\n$29 per 90, 160 mg tablets of generic Diovan at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Vasotec<\/span><\/a> (enalapril)<\/span><\/a><\/td>\n$1,003 per 30, 20 mg tablets<\/span><\/td>\n$9 per 30, 20 mg tablets of generic Vasotec at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Coreg<\/span><\/a> (carvedilol)<\/span><\/a><\/td>\n$1,135 per 60, 12.5 mg tablets<\/span><\/td>\n$6 per 60, 12.5 mg tablets of generic Coreg at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
BiDil<\/span><\/a> (<\/span>isosorbide dinitrate\/hydralazine<\/span><\/a>)<\/span><\/td>\n$473 per 90, 20\/37.5 mg tablets<\/span><\/td>\n$65 per 90, 20\/37.5 mg tablets of generic BiDil at CVS<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Aldactone<\/span><\/a> (spironolactone)<\/span><\/a><\/td>\n$109 per 30, 25 mg tablets<\/span><\/td>\n$4 per 30, 25 mg tablets of generic Aldactone at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Farxiga<\/span><\/a> (<\/span>dapagliflozin<\/span><\/a>)<\/span><\/td>\n$822 per 30, 10 mg tablets<\/span><\/td>\n$361 per 30, 10 mg tablets of generic Farxiga at Walgreens<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of November 18, 2025. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under \u201cSavings options\u201d to see the latest drug prices.<\/span><\/i><\/p>\n

RELATED: <\/b>Entresto alternatives: What can I take instead of Entresto?<\/b><\/a><\/p>\n

Entresto costs by dose<\/span><\/h2>\n

Entresto is a premium-priced brand-name medication, so prices do not vary by dosage strength. Entresto is only packaged in quantities of 60 tablets and typically dispensed from the pharmacy as a 30-day supply, so savings are usually not feasible by seeking out 90-day supplies of the drug.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n
\n

Compare Entresto prices by strength<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

(per 60 tablets)<\/span><\/i><\/td>\n<\/tr>\n
Strength<\/b><\/td>\nSingleCare price of brand-name Entresto\u00a0<\/b><\/td>\nSingleCare price of generic Entresto\u00a0<\/b><\/td>\n<\/tr>\n
24-26 mg of Entresto<\/span><\/td>\n$692 at Walgreens<\/span><\/td>\n$50 at CVS<\/span><\/td>\n<\/tr>\n
49-51 mg of Entresto<\/span><\/td>\n$691 at Walgreens<\/span><\/td>\n$50 at CVS<\/span><\/td>\n<\/tr>\n
97-103 mg of Entresto<\/span><\/td>\n$691 at Walgreens<\/span><\/td>\n$50 at CVS<\/span><\/td>\n<\/tr>\n
See our lowest price for Entresto without insurance<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of November 18, 2025.<\/span><\/i><\/p>\n\t\t

\n\t\t\t

Save up to 80% on Entresto with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tEntresto 24-26 mg (60 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"CVS\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$34.83\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Publix\"\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$52.71\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Entresto prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

Is Entresto covered by insurance?<\/span><\/h2>\n

Nearly all commercial and private insurance plans, Medicare Part D plans, and state Medicaid plans cover Entresto or its generic version, sacubitril-valsartan. Insurance providers generally do not require prior authorization, but they may reject an Entresto prescription if the generic version hasn\u2019t been tried.\u00a0<\/span><\/p>\n

Health insurance can significantly reduce the cost of Entresto, but the out-of-pocket cost will depend on the plan\u2019s deductible and the copay cost determined by the plan\u2019s formulary. For additional savings, Novartis Pharmaceuticals, the manufacturer of Entresto, has a copay offer for people on Medicare or commercial health insurance.<\/span><\/p>\n

How to get Entresto without insurance<\/span><\/h2>\n

Paying for an Entresto prescription without insurance will be challenging. With a total calendar year cost approaching $11,000, Entresto can be a significant financial responsibility for people without insurance. The manufacturer may offer patient assistance programs, but not everyone will meet the strict eligibility requirements. Fortunately, there are a variety of ways to save money on Entresto.<\/span><\/p>\n

1. Save instantly with a SingleCare savings card<\/span><\/h3>\n

In just a few minutes, people could save hundreds of dollars by using a <\/span>free Entresto coupon from SingleCare<\/span><\/a>. For example, a 30-day supply of generic Entresto costs $50 at CVS with SingleCare. Read the FAQs section on the Entresto coupon page for additional information about paying for Entresto. For additional savings on refills and future drug purchases, join SingleCare\u2019s bonus loyalty program.\u00a0<\/span><\/p>\n

2. Switch to generic Entresto<\/span><\/h3>\n

A 30-day supply of generic sacubitril-valsartan costs $255 on average without insurance. A SingleCare savings card can reduce the cost to as little as $50 at CVS. That\u2019s $900 less than the average cost of Entresto tablets. Most people with insurance will start with generic Entresto, so it makes sense for uninsured patients to start treatment the same way.\u00a0<\/span><\/p>\n

3. Look for the lowest price<\/span><\/h3>\n

Entresto has a manufacturer\u2019s list price, but the actual price charged by the pharmacy is usually higher \u2026 sometimes much higher. Check with several pharmacies before filling an Entresto prescription.\u00a0<\/span><\/p>\n

4. Ask the prescriber about alternative heart failure treatments<\/span><\/h3>\n

Entresto is the only prescription drug available that contains sacubitril. There is no other drug that works like sacubitril. However, there are other drug combinations used to treat heart failure, drugs that can be purchased as lower-cost generics. If Entresto is too expensive, ask a healthcare provider for medical advice about lower-priced drug combinations.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Entresto is a brand-name prescription drug used to reduce the risk of serious cardiovascular events and hospitalization in adults and children with chronic heart failure. A combination of two drugs, sacubitril and valsartan, Entresto relaxes blood vessels and reduces blood pressure, leading to reduced strain on the heart and slowing the progression of heart failure. 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Here's how to save.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/entresto-without-insurance\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"How much is Entresto without insurance?\" \/>\n<meta property=\"og:description\" content=\"See how you can save\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/entresto-without-insurance\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-02T20:47:17+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-11T14:15:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/03\/Entresto_without_insurance.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"SingleCare Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:description\" content=\"See how you can save\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"SingleCare Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/\"},\"author\":{\"name\":\"SingleCare Team\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/403ef50a9f402fb9ce49c429659555f5\"},\"headline\":\"How much is Entresto without insurance?\",\"datePublished\":\"2022-04-02T20:47:17+00:00\",\"dateModified\":\"2025-12-11T14:15:35+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/\"},\"wordCount\":1072,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/03\\\/Entresto_without_insurance.png\",\"keywords\":[\"Drug pricing\",\"Health insurance\",\"Heart health\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/\",\"name\":\"How much does Entresto cost without insurance?\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/entresto-without-insurance\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/03\\\/Entresto_without_insurance.png\",\"datePublished\":\"2022-04-02T20:47:17+00:00\",\"dateModified\":\"2025-12-11T14:15:35+00:00\",\"description\":\"Entresto without insurance costs $16 per tablet, or $969 per month for 60, 24\\\/26 mg tablets. 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