{"id":50295,"date":"2022-05-07T21:41:26","date_gmt":"2022-05-08T01:41:26","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=50295"},"modified":"2025-10-14T11:28:24","modified_gmt":"2025-10-14T15:28:24","slug":"linzess-without-insurance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/linzess-without-insurance\/","title":{"rendered":"How much is Linzess without insurance?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Linzess (linaclotide) is a brand-name prescription drug prescribed to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/ibs-treatment-and-medications\"><span style=\"font-weight: 400;\">irritable bowel syndrome<\/span><\/a><span style=\"font-weight: 400;\"> with constipation (IBS-C) and <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/constipation-treatment-and-medications\"><span style=\"font-weight: 400;\">chronic idiopathic constipation<\/span><\/a><span style=\"font-weight: 400;\"> (CIC). The dosage will depend on the underlying condition, but it should not affect the price. There is no generic version of Linzess, so people without insurance will have to pay the full retail price for treatment. There are Linzess savings options, and the first and most reliable is a SingleCare savings coupon.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/linzess-side-effects\/\"><b>Linzess side effects<\/b><\/a><\/p>\n<h2 id=\"how-much-does-linzess-cost-without-insurance\"><span style=\"font-weight: 400;\">How much does Linzess cost without insurance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The retail cash price of Linzess is $753 per month without insurance. That\u2019s roughly $25 per capsule. For people on long-term therapy, the total cost can be as much as $9,000 per year.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Alternatives are limited. The active ingredient in Linzess, linaclotide, belongs to a family of drugs called secretagogues. It works by stimulating the lining of the small intestine to secrete more fluids into the small intestine and colon, speeding up the movement of waste products. The only other prescription drug that works just like Linzess, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/trulance-vs-linzess\/\"><span style=\"font-weight: 400;\">Trulance (plecanatide)<\/span><\/a><span style=\"font-weight: 400;\">, is also sold exclusively as a brand-name drug. It costs even more than Linzess.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although it works differently, another prosecretory treatment for constipation is <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/amitiza-vs-linzess\/\"><span style=\"font-weight: 400;\">Amitiza (lubiprostone)<\/span><\/a><span style=\"font-weight: 400;\">, a drug with a long history and a lower-priced generic version. Amitiza is also approved by the Food and Drug Administration to treat constipation associated with irritable bowel syndrome.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Most patients with IBS-C or CIC have used cheaper, over-the-counter laxatives such as docusate, senna products, and Miralax (polyethylene glycol), but <\/span><a href=\"https:\/\/www.ajmc.com\/view\/update-on-the-management-of-chronic-idiopathic-constipati\"><span style=\"font-weight: 400;\">dissatisfaction with these treatments is high<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"how-much-does-brand-name-generic-linzess-cost\"><span style=\"font-weight: 400;\">How much does brand-name\/generic Linzess cost?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There is no generic version of Linzess available. A generic version of Linzess is expected to be available in March of 2029. Low-dose linaclotide (72 mcg) will not be available until 2031 at the earliest.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th colspan=\"4\">\n<h3 id=\"compare-linzess-prices-to-related-drugs\"><span style=\"font-weight: 400;\">Compare Linzess prices to related drugs<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Price without insurance\u00a0<\/b><\/td>\n<td><b>SingleCare price<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/linzess\/what-is\"><span style=\"font-weight: 400;\">Linzess<\/span><span style=\"font-weight: 400;\"> (<\/span><\/a><span style=\"font-weight: 400;\">linaclotide<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/linzess\/what-is\"><span style=\"font-weight: 400;\">)\u00a0<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$753 per 30, 145 mcg capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$500 per 30, 145 mcg capsules of brand-name Linzess<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/linzess\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/amitiza\/what-is\"><span style=\"font-weight: 400;\">Amitiza <\/span><\/a><a href=\"https:\/\/www.singlecare.com\/prescription\/lubiprostone\/what-is\"><span style=\"font-weight: 400;\">(lubiprostone)<\/span><\/a><a href=\"https:\/\/www.singlecare.com\/prescription\/amitiza\/what-is\"><span style=\"font-weight: 400;\">\u00a0<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$514 per 60, 24 mcg capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$40 per 60, 24 mcg capsules<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/amitiza\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/trulance\/what-is\"><span style=\"font-weight: 400;\">Trulance<\/span><\/a> <span style=\"font-weight: 400;\">(plecanatide)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$817 per 30, 3 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$506 per 30, 3 mg tablets of brand-name Trulance<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/trulance\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/dicyclomine-hcl\/what-is\"><span style=\"font-weight: 400;\">Dicyclomine<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$20 per 20, 20 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$3 per 20, 20 mg tablets<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/dicyclomine-hcl\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/kristalose\/what-is\"><span style=\"font-weight: 400;\">Kristalose<\/span><\/a><span style=\"font-weight: 400;\"> (lactulose powder for solution)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$421 per 30, 20 gm packets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$92 per 30, 20 gm packets<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/kristalose\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/lactulose\/what-is\"><span style=\"font-weight: 400;\">Lactulose (oral solution<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$64 per 473 mL of 10 gm\/15 mL bottle<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9 per 473 mL of 10 gm\/15 mL bottle<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lactulose\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/motegrity\/what-is\"><span style=\"font-weight: 400;\">Motegrity<\/span><\/a><span style=\"font-weight: 400;\"> (prucalopride)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$735 per 30, 2 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$274 per 30, 2 mg tablets<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/motegrity\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><i><span style=\"font-weight: 400;\">Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in zip code <\/span><\/i><i><span style=\"font-weight: 400;\">23666<\/span><\/i><i><span style=\"font-weight: 400;\">. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under <\/span><\/i><i><span style=\"font-weight: 400;\">\u201cSavings options\u201d<\/span><\/i><i><span style=\"font-weight: 400;\"> to see the latest drug prices.<\/span><\/i><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/linzess-alternatives\/\"><b>Linzess alternatives: What can I take instead of Linzess?<\/b><\/a><\/p>\n<h2 id=\"linzess-costs-by-dose\"><span style=\"font-weight: 400;\">Linzess costs by dose<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The retail price of Linzess should not vary by dosage strength, though prices will vary between pharmacies. Quantities may also affect prices, but most pharmacies offer only a 30-day supply of Linzess at a time.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th colspan=\"3\">\n<h3 id=\"compare-linzess-prices-by-strength\"><span style=\"font-weight: 400;\">Compare Linzess prices by strength<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Strength<\/b><\/td>\n<td><b>SingleCare price of brand-name Linzess<\/b><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">72 mcg of Linzess<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$492<\/span><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">145 mcg of Linzess<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$500<\/span><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">290 mcg of Linzess<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$511<\/span><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;\" colspan=\"3\"><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/linzess\"><span style=\"font-weight: 400;\">See our lowest price for Linzess without insurance<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Linzess with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tLinzess 145 mcg (30 capsules)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$252.26<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/linzess#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/linzess#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$252.26<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/linzess#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/linzess#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/linzess#blog-cta\" class=\"coupon-see-all-btn\">See Linzess prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"is-linzess-covered-by-insurance\"><span style=\"font-weight: 400;\">Is Linzess covered by insurance?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">98% of commercial insurance plans cover Linzess prescriptions to some extent, according to the <\/span><a href=\"https:\/\/www.linzesshcp.com\/formulary-coverage\"><span style=\"font-weight: 400;\">manufacturer<\/span><\/a><span style=\"font-weight: 400;\">. Nearly all (93%) Medicare Part D drug coverage beneficiaries have Linzess coverage. However, some insurance companies may require prior authorization or that other, less-expensive prescription drugs be tried first. Most people with insurance pay $30 or less for Linzess for a one-month supply. Keep in mind, however, that number includes people who use a Linzess copay savings card from Allergan to manage higher copays. Additionally, people on a high-deductible insurance plan or Medicare beneficiaries who are stuck in the donut hole may be looking for additional prescription savings.<\/span><\/p>\n<h3 id=\"how-to-get-linzess-covered-by-insurance\"><span style=\"font-weight: 400;\">How to get Linzess covered by insurance<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Although nearly all health insurance plans and Medicare prescription drug plans cover Linzess, the insurance provider may reject a Linzess prescription. The most common reason is that certain requirements have not been met, such as those related to step therapy or prior authorization. Discuss with the prescribing healthcare professional how to meet these requirements or file an appeal.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For people on health insurance plans that do not cover Linzess, ask the prescriber about filing a formulary exemption. The process is similar to prior authorization, but the clinician must submit a letter of medical necessity justifying the prescription. Even when granted, the copay and out-of-pocket costs may be very high.<\/span><\/p>\n<h2 id=\"how-to-get-linzess-without-insurance\"><span style=\"font-weight: 400;\">How to get Linzess without insurance<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">With an annual out-of-pocket cost of $9,000, Linzess can present a financial challenge for individuals without insurance coverage. Fortunately, there are many savings options to explore, such as manufacturer coupons and patient assistance programs, including the manufacturer\u2019s Linzess savings programs. All these programs require enrollment, and not everyone will be able to meet the eligibility criteria, however. Fortunately, there are more options to save money on Linzess, starting with SingleCare\u2019s prescription savings program.<\/span><\/p>\n<h3 id=\"1-use-a-singlecare-savings-card\"><span style=\"font-weight: 400;\">1. Use a SingleCare savings card<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">All customers can get immediate prescription savings simply by using a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/linzess\"><span style=\"font-weight: 400;\">free SingleCare Linzess coupon<\/span><\/a><span style=\"font-weight: 400;\"> at a participating pharmacy. Get a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/linzess\"><span style=\"font-weight: 400;\">free Linzess coupon here<\/span><\/a><span style=\"font-weight: 400;\"> and compare discount prices at your local pharmacies. While there, check the FAQs section for additional information about insurance coverage and savings. Make sure to <\/span><a href=\"https:\/\/www.singlecare.com\/signup\"><span style=\"font-weight: 400;\">sign up for SingleCare\u2019s loyalty savings program<\/span><\/a><span style=\"font-weight: 400;\">. Each SingleCare purchase earns future savings on refills and other drugs.<\/span><\/p>\n<h3 id=\"2-ask-for-a-free-sample\"><span style=\"font-weight: 400;\">2. Ask for a free sample<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If you\u2019re in a pinch, your healthcare professional may have free samples available. Unfortunately, free samples usually only cover a week or two. Still, this buys time to find other ways to make treatment more affordable.<\/span><\/p>\n<h3 id=\"3-switch-to-lubiprostone\"><span style=\"font-weight: 400;\">3. Switch to lubiprostone<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Generic lubiprostone works in a slightly different way than Linzess, but it has the same effects. The average retail cost of generic lubiprostone is about $451 per 60 capsules (at the standard 24 mcg dose). That\u2019s still higher than many common generic drugs, but it\u2019s close to half the cost of Linzess. Use a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare discount card<\/span><\/a><span style=\"font-weight: 400;\"> when purchasing lubiprostone to reduce the cost to just $40 per month for 60 capsules. Ask the prescribing healthcare professional for medical advice before switching.<\/span><\/p>\n<h3 id=\"4-compare-pharmacy-prices\"><span style=\"font-weight: 400;\">4. Compare pharmacy prices<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">It\u2019s always a good idea to shop around for the lowest price. Prices for brand-name prescription medications, such as Linzess, can vary between retail pharmacies. It\u2019s possible to save extra money on a Linzess prescription simply by shopping for the lowest price.\u00a0<\/span><\/p>\n<h3 id=\"5-reconsider-over-the-counter-laxatives\"><span style=\"font-weight: 400;\">5. Reconsider over-the-counter laxatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Chances are, patients with IBS-C or CIC have a long history with laxatives, but have had problems with ineffectiveness or side effects. However, if Linzess treatment is financially challenging, consider talking to the prescribing healthcare provider about the most suitable <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/laxatives\/\"><span style=\"font-weight: 400;\">over-the-counter laxative options<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/home-remedies-for-constipation\/\"><span style=\"font-weight: 400;\">home remedies<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/linzess-side-effects\/\"><b>Linzess side effects and how to avoid them<\/b><\/a><\/p>\n<h2 id=\"expert-takeaway\"><span style=\"font-weight: 400;\">Expert Takeaway<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cBy the time patients come to my office for symptoms of chronic constipation or IBS-C, they have usually tried multiple over-the-counter laxatives and even one or more prescription medications\u201d, reports Dr. Jesse P. Houghton, MD, senior medical director of gastroenterology at Southern Ohio Medical Center. \u201cI always take a detailed history of exactly which laxatives they have tried, how long they took them for, and the reasons that they stopped taking them. Ultimately, some patients will require more than one medication to effectively treat their chronic constipation\u201d, says Dr. Houghton. Examples include Linzess with senna, or Amitiza with polyethylene glycol (Miralax). Always talk with your provider to see if combining medications is a viable option for your symptoms.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Linzess (linaclotide) is a brand-name prescription drug prescribed to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). The dosage will depend on the underlying condition, but it should not affect the price. There is no generic version of Linzess, so people without insurance will have to pay the full retail price [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":50296,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[16414,15103,608],"coauthors":[8861],"class_list":["post-50295","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-digestive-health","tag-drug-pricing","tag-health-insurance","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>How much does Linzess cost without insurance?<\/title>\n<meta name=\"description\" content=\"Linzess without insurance costs $25 per capsule, or $753 per month for 30 capsules. 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