{"id":50704,"date":"2022-04-15T09:30:20","date_gmt":"2022-04-15T13:30:20","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=50704"},"modified":"2022-04-11T15:58:20","modified_gmt":"2022-04-11T19:58:20","slug":"buspirone-and-caffeine","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/buspirone-and-caffeine\/","title":{"rendered":"Does caffeine interact with buspirone?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl\/what-is\"><span style=\"font-weight: 400;\">Buspirone<\/span><\/a><span style=\"font-weight: 400;\">, also known by the brand name <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/buspar-for-anxiety\/\"><span style=\"font-weight: 400;\">BuSpar<\/span><\/a><span style=\"font-weight: 400;\">, is an anti-anxiety medication. Many anti-anxiety medications (anxiolytics) are benzodiazepines (such as Xanax), but buspirone is classified as a non-benzodiazepine <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anxiolytics\"><span style=\"font-weight: 400;\">anxiolytic<\/span><\/a><span style=\"font-weight: 400;\">. It\u2019s used to treat generalized anxiety disorder (GAD), which is when you experience excessive anxiety for at least six months. Symptoms of anxiety include restlessness, irritability, fatigue, muscle tension, and difficulty concentrating.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Your healthcare provider can prescribe buspirone tablets in a variety of strengths, making it easy to fine-tune dosages for. Buspirone works by regulating serotonin and dopamine receptors in the brain. \u201cIt can take up to four weeks for the full effects of buspirone to set in,\u201d says <\/span><a href=\"https:\/\/www.linkedin.com\/in\/akos-antwi-6b41b31a1\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Akos Antwi, PMHNP<\/span><\/a><span style=\"font-weight: 400;\">, a psychiatric nurse practitioner and co-owner of <\/span><a href=\"https:\/\/revivetherapeuticservices.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Revive Therapeutic Services<\/span><\/a><span style=\"font-weight: 400;\">. As a result, it\u2019s unlikely to be addictive, but you shouldn\u2019t stop taking buspirone suddenly or without medical advice. Doing so could cause symptoms of withdrawal.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like other psychotropic drugs, buspirone may affect mood and energy levels. Other side effects may include nervousness, increased heart rate, insomnia, and upset stomach. If you\u2019re a coffee drinker, you may also recognize these as common side effects of caffeine. So, you may wonder if you can start your mornings with buspirone <\/span><i><span style=\"font-weight: 400;\">and <\/span><\/i><span style=\"font-weight: 400;\">coffee?<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl\"><b>Buspirone coupons<\/b><\/a><\/p>\n<h2><span style=\"font-weight: 400;\">How does caffeine affect buspirone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">\u201cBuspirone and caffeine are not strictly contraindicated,\u201d according to <\/span><a href=\"https:\/\/www.theohanahawaii.com\/team\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Michael J. McGrath, MD<\/span><\/a><span style=\"font-weight: 400;\">, medical director of The Ohana. In other words, there is no known caffeine and buspirone interaction.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, consuming buspirone and coffee may lead to an increase in anxiety and nervousness, so it is usually not recommended. Caffeine doesn\u2019t behave the same way with all anti-anxiety medications. Some other anxiety medications, like <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/xanax-and-coffee\/\"><span style=\"font-weight: 400;\">Xanax<\/span><\/a><span style=\"font-weight: 400;\">, are depressants. Since depressants slow down the central nervous system to help patients feel more relaxed and caffeine is a stimulant that heightens the central nervous system, they may cancel each other out.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/buspirone-vs-xanax\/\"><b>Buspirone vs. Xanax<\/b><\/a><\/p>\n<h2><span style=\"font-weight: 400;\">Does buspirone keep you awake?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Insomnia is a potential side effect of buspirone\u2014but not common. The package insert for Buspirone says that 3% of people taking the medication experience insomnia; similarly, 3% of people on a placebo do as well. While buspirone is not overly sedating, like many other anti-anxiety medications, it generally won\u2019t keep you awake. It may even help if anxiety is preventing you from falling asleep.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How should I take buspirone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Your provider will tell you the dosage, frequency, and time you should take buspirone. Most people who take buspirone do so two or three times a day.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you miss a dose of buspirone, take it as soon as possible. However, if it&#8217;s almost time for your next dose, you should take the next dose and skip the missed dose. Don\u2019t take more buspirone than prescribed by your doctor. If you&#8217;re forgetful, you may benefit from setting an alarm so you don\u2019t forget to take buspirone.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Can BuSpar make anxiety worse?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Buspirone does not always work as expected. \u201cBuSpar can make anxiety worse. If you experience worsening anxiety or nervousness when taking BuSpar, talk to your physician,\u201d says Dr. McGrath. You should tell your provider if you\u2019re experiencing any thoughts about suicide or self-harm, or contact a suicide prevention hotline. They should also be aware of any other psychiatric or medical conditions you have as well as any other treatments you\u2019re receiving, such as talk therapy. This way, your provider can make informed decisions about your course of treatment and provide the best care possible.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What should you not take with BuSpar?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While it may be wise to avoid mixing caffeine and buspirone, it\u2019s not a dangerous combination. However, there are other drugs and substances that you should avoid while taking buspirone, such as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/maois\"><span style=\"font-weight: 400;\">MAOIs<\/span><\/a><span style=\"font-weight: 400;\">, erythromycin, and diltiazem.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you\u2019re taking a monoamine oxidase inhibitor (MAOI), taking buspirone at the same time can dramatically increase the amount of serotonin in your brain, inducing serotonin syndrome. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/serotonin-syndrome-symptoms\/\"><span style=\"font-weight: 400;\">Symptoms of serotonin syndrome<\/span><\/a><span style=\"font-weight: 400;\"> may be life threatening, and are cause for emergency medical attention.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You shouldn\u2019t take buspirone with <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">SSRI<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/snris\"><span style=\"font-weight: 400;\">SNRI<\/span><\/a><span style=\"font-weight: 400;\"> antidepressants like fluoxetine or venlafaxine, respectively. You should also avoid certain <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/macrolides\"><span style=\"font-weight: 400;\">antibiotics<\/span><\/a><span style=\"font-weight: 400;\"> such as erythromycin, and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antifungals\"><span style=\"font-weight: 400;\">antifungals<\/span><\/a><span style=\"font-weight: 400;\"> like fluconazole.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You shouldn\u2019t take certain supplements, like St. John\u2019s Wort, with buspirone. These may reduce the effectiveness of buspirone or cause an unwanted interaction.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Don\u2019t consume alcohol, grapefruit, or grapefruit juice while taking buspirone. \u201cGrapefruit juice increases blood plasma levels of buspirone,\u201d Dr. McGrath explains. This can increase side effects of buspirone. Medications like rifampin may generate the opposite effect, decreasing blood plasma levels of buspirone and making it less effective.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">You should always talk to your doctor before you start any new drugs, supplements, or vitamins. Doing so without medical advice could lead to dangerous interactions with buspirone.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Buspirone, also known by the brand name BuSpar, is an anti-anxiety medication. Many anti-anxiety medications (anxiolytics) are benzodiazepines (such as Xanax), but buspirone is classified as a non-benzodiazepine anxiolytic. It\u2019s used to treat generalized anxiety disorder (GAD), which is when you experience excessive anxiety for at least six months. Symptoms of anxiety include restlessness, irritability, [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":50697,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9777,814],"coauthors":[20896],"class_list":["post-50704","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-anxiety","tag-drug-interactions","franchise-the-jolt","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can you drink caffeine with BuSpar (buspirone)?<\/title>\n<meta name=\"description\" content=\"There are no interactions between BuSpar and caffeine, but mixing them may worsen anxiety. There are other more dangerous buspirone interactions to be aware of.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/buspirone-and-caffeine\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Can you drink coffee with this anti-anxiety med?\" \/>\n<meta property=\"og:description\" content=\"Buspirone and caffeine don\u2019t interact, but there are a few things to know\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/buspirone-and-caffeine\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2022-04-15T13:30:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/04\/Blog_041522_Caffeine_interact_buspirone.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Brianna Graham, MPH\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Can you drink coffee with this anti-anxiety med?\" \/>\n<meta name=\"twitter:description\" content=\"Buspirone and caffeine don\u2019t interact, but there are a few things to know\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Brianna Graham, MPH\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/\"},\"author\":{\"name\":\"Mariusz Labedzki\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/232380d21234706e6360acfa9c895934\"},\"headline\":\"Does caffeine interact with buspirone?\",\"datePublished\":\"2022-04-15T13:30:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/\"},\"wordCount\":802,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/04\\\/Blog_041522_Caffeine_interact_buspirone.png\",\"keywords\":[\"Anxiety\",\"Drug interactions\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/\",\"name\":\"Can you drink caffeine with BuSpar (buspirone)?\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/buspirone-and-caffeine\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/04\\\/Blog_041522_Caffeine_interact_buspirone.png\",\"datePublished\":\"2022-04-15T13:30:20+00:00\",\"description\":\"There are no interactions between BuSpar and caffeine, but mixing them may worsen anxiety. 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