{"id":50856,"date":"2022-04-18T10:05:35","date_gmt":"2022-04-18T14:05:35","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=50856"},"modified":"2026-07-10T18:42:00","modified_gmt":"2026-07-10T22:42:00","slug":"metoprolol-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/metoprolol-alternatives\/","title":{"rendered":"Metoprolol (Lopressor) alternatives: What can I take instead of metoprolol?"},"content":{"rendered":"

Lopressor<\/a> (metoprolol tartrate) is a brand-name medication in a well-known drug class called beta blockers. It is approved by the Food and Drug Administration (FDA) for use in the management of several cardiovascular conditions, including high blood pressure<\/a> (hypertension), chest pain (angina), and myocardial infarction (MI, or a heart attack). Off-label use occurs in the setting of heart arrhythmias like atrial fibrillation<\/a> (AFib), hyperthyroidism, and migraine<\/a> prevention. Being that there are numerous potential uses, there are plentiful alternatives to Lopressor, which could have advantages based on the underlying condition, drug interactions, or adverse effects. Here, we will discuss the reasons why a patient may need to seek an alternative to Lopressor.\u00a0<\/p>\n

What can I take instead of metoprolol?<\/b><\/h2>\n

Options to replace metoprolol start within the beta blocker class. Differences between beta blockers are significant, including the risk of adverse effects and their duration of action. Other drug classes used to treat similar conditions as beta blockers include angiotensin-converting enzyme inhibitors<\/a> (ACEIs), angiotensin II receptor blockers<\/a> (ARBs), aldosterone antagonists<\/a>, calcium channel blockers<\/a> (CCBs), vasodilators<\/a>, diuretics<\/a>, and medications that control the heart rate or heart rhythm<\/a>. Besides comparing the beneficial effects and risks among these alternatives, price should also be considered.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare metoprolol alternatives<\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Lopressor\u00a0<\/a><\/p>\n

(metoprolol tartrate, immediate-release<\/a>)\u00a0<\/td>\n

$192 per 60, 50 mg tablets<\/td>\n$7 per 60, 50 mg tablets of generic metoprolol tartrate, immediate-release at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Toprol XL\u00a0<\/a><\/p>\n

(metoprolol succinate, extended release<\/a>)\u00a0<\/td>\n

$160 per 90, 25 mg tablets<\/td>\n$9 per 90, 25 mg tablets of generic metoprolol succinate, extended-release at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Coreg\u00a0<\/a><\/p>\n

(carvedilol<\/a>)\u00a0<\/td>\n

$1,135 per 60, 12.5 mg tablets<\/td>\n$6 per 60, 12.5 mg tablets of generic carvedilol at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Tenormin<\/a> (atenolol<\/a>)\u00a0<\/td>\n$497 per 30, 25 mg tablets<\/td>\n$4 per 30, 25 mg tablets of generic atenolol at Kroger<\/td>\nSee latest prices<\/a>\u00a0<\/td>\n<\/tr>\n
Bystolic<\/a> (nebivolol<\/a>)\u00a0<\/td>\n$709 per 90, 5 mg tablets<\/td>\n$32 per 90, 5 mg tablets of generic nebivolol at CVS<\/td>\nSee latest prices<\/a>\u00a0<\/td>\n<\/tr>\n
Corgard<\/a> (nadolol)\u00a0<\/td>\n$105 per 30, 20 mg tablets<\/td>\n$12 per 30, 20 mg tablets of generic nadolol at Kroger<\/td>\nSee latest prices<\/a>\u00a0<\/td>\n<\/tr>\n
Inspra<\/a> (eplerenone)\u00a0<\/td>\n$533 per 30, 25 mg tablets<\/td>\n$20 per 30, 25 mg tablets of generic eplerenone at Kroger<\/td>\nSee latest prices<\/a>\u00a0<\/td>\n<\/tr>\n
Aldactone <\/a>(spironolactone<\/a>)\u00a0<\/td>\n$109 per 30, 25 mg tablets<\/td>\n$4 per 30, 25 mg tablets of generic spironolactone at Kroger<\/td>\nSee latest prices<\/a>\u00a0<\/td>\n<\/tr>\n
Zestril\u00a0<\/a><\/p>\n

(lisinopril<\/a>)\u00a0<\/td>\n

$1,434 per 90, 10 mg tablets<\/td>\n$7 per 90, 10 mg tablets at Kroger<\/td>\nSee latest prices<\/a>\u00a0<\/td>\n<\/tr>\n
Diovan (valsartan)<\/td>\n$1,136 per 90, 160 mg tablets<\/td>\n$29 per 90, 160 mg tablets of generic valsartan at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Hydrochlorothiazide<\/a><\/td>\n$20 per 30, 25 mg tablets<\/td>\n$4 per 30, 25 mg tablets of generic hydrochlorothiazide at Walmart<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Norvasc (amlodipine<\/a>)<\/td>\n$420 per 30, 10 mg tablets<\/td>\n$4 per 30, 10 mg tablets of generic amlodipine at Kroger<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Cardizem CD (diltiazem, extended-release<\/a>)<\/td>\n$3,128 per 90, 120 mg capsules<\/td>\n$10 per 30, 120 mg capsules of generic diltiazem, extended-release at Walmart<\/td>\nSee latest prices<\/a><\/td>\n<\/tr>\n
Verelan\u00a0<\/p>\n

(verapamil)\u00a0<\/td>\n

$38 per 90, 80 mg tablets<\/td>\n$9 per 90, 80 mg capsules of generic verapamil at Kroger<\/td>\nSee latest prices\u00a0<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under \u201cSavings options\u201d to see the latest drug prices.<\/i><\/small><\/small><\/p>\n\t\t

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Save up to 80% on Metoprolol with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tMetoprolol 25 mg (60 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$4.13\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$4.13\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Metoprolol prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

Top 5 metoprolol alternatives<\/h2>\n

The following are some of the most common alternatives to metoprolol.<\/p>\n

1. Toprol XL<\/b><\/h3>\n

Toprol XL (metoprolol succinate extended-release) is a beta blocker that has an FDA-approved indication for the management of heart failure. Beta blockers<\/a> in the setting of heart failure are generally indicated for those with heart failure with reduced ejection fraction (HFrEF). Unlike metoprolol tartrate<\/a>, Toprol XL is an extended-release formulation of metoprolol succinate. Toprol XL demonstrated a reduction<\/a> in cardiovascular complications and hospitalization in HFrEF when compared to placebo. Toprol XL is a preferred beta blocker (over immediate-release metoprolol tartrate) in the management of HFrEF. In comparison to immediate-release metoprolol, it can be administered once daily.\u00a0<\/p>\n

2. Coreg<\/b><\/h3>\n

Coreg (carvedilol) is an agent with some alpha blocker activity in addition to its beta-blockade and is an alternative to metoprolol tartrate for hypertension. It is also indicated for the management of HFrEF. Coreg has demonstrated a reduction in mortality in both moderate to severe stages of heart failure, with the most substantial evidence for benefit in severe failure<\/a>. Since it does exhibit some alpha blocker activity, it can cause peripheral vasodilation (or relaxation of blood vessels) and lower blood pressure more in comparison to metoprolol.<\/p>\n

The beta blocker drug class can be further subclassified as non-selective agents, cardio-selective agents, and agents with alpha-1 antagonist activity. Metoprolol is a cardio-selective beta blocker and may be a preferred agent to manage patients with underlying conditions like hypertension or heart disease who also suffer from chronic obstructive pulmonary disease (COPD<\/a>) or asthma. Being cardio-selective, metoprolol will mostly block beta receptors on the heart. Beta receptors are also found throughout pulmonary tissue, and if blockage of those receptors occurs, it can exacerbate lung conditions like COPD. Carvedilol is non-selective, so it may cause these patients problems.<\/p>\n

3. Norvasc<\/b><\/h3>\n

Beta blockers are not a preferred or first-line drug for most people with hypertension. Norvac (amlodipine), which is a dihydropyridine calcium channel blocker, is a more common pick, according to guidelines from the World Health Organization<\/a>. Guidelines such as these are generally based on efficacy and safety findings from clinical trials. Side effects of metoprolol that may require seeking alternative therapy, such as amlodipine, include a decreased heart rate (bradycardia) and a tendency to cause mild weight gain<\/a>.\u00a0<\/p>\n

4. Zestril<\/b><\/h3>\n

Other first-line antihypertensive classes, ARBs, like Diovan (valsartan), and ACEi, such as Zestril (lisinopril), may be suitable alternatives to metoprolol when trying to lower blood pressure. Lisinopril can help meet American College of Cardiology guideline recommendations<\/a> to achieve a systolic blood pressure of less than 130 mmHg and a diastolic blood pressure of less than 80 mmHg. In patients with underlying kidney disease resulting in proteinuria, lisinopril can be a good option for therapy as well. Combining an ACEi with a thiazide diuretic<\/a> like hydrochlorothiazide is frequently done.<\/p>\n

5. Verelan<\/b><\/h3>\n

Verelan (verapamil) and Cardizem CD (diltiazem extended-release) are two calcium channel blockers from the non-dihydropyridine subcategory. Guidelines for hypertension management do not recommend their use in most cases. However, they can have a dual benefit when angina treatment or heart rate control is important, too. Atrial fibrillation, an irregular heart rhythm that often goes too fast, is common, and a heart rate-controlling medication like verapamil can be helpful. It is usually preferred over\u00a0metoprolol\u00a0in the setting of COPD or bronchospasm for this use, but is typically avoided in the management of HFrEF.<\/p>\n

Natural alternatives to metoprolol<\/b><\/h2>\n

For the conditions in which metoprolol is used as pharmacologic management, many lifestyle changes and diet modifications can be undertaken simultaneously to improve long-term outcomes. In the setting of hypertension, the American College of Cardiology guidelines suggest that each kilogram of weight lost can reduce systolic blood pressure (SBP) by 1 mmHg, a heart-healthy diet<\/a> can reduce SBP by 11 mmHg, cutting dietary sodium intake by 25% can reduce SBP by 5 mmHg, and following a structured exercise program of at least 150 minutes of aerobic activity each week can reduce SBP by 5 mmHg. As always, one should seek the medical advice of healthcare professionals before seeking natural alternatives to metoprolol tartrate.\u00a0<\/p>\n

How to switch to a metoprolol alternative<\/b><\/h2>\n

Before switching metoprolol to one of its alternatives, it is best to do so in conjunction with the medical advice of a healthcare professional. Reasons for alternatives to be considered suboptimal therapeutic options based on your unique situation may not be obvious, and it is important to have these alternatives evaluated carefully by a healthcare provider who knows the entirety of your medical history. In addition, abrupt discontinuation<\/a> of long-term use of beta blockers like metoprolol can cause withdrawal-like symptoms, resulting in rebound hypertension, tachycardia, heart arrhythmias, or an angina attack. Therefore, beta blocker must be slowly tapered off over the course of a week or longer, at which time alternative medications can then be added. Using a prescription discount card<\/a> from SingleCare may help reduce the cost of metoprolol and its alternatives at participating pharmacies<\/a>.<\/p>\n

Choosing the right path for hypertension treatment<\/h2>\n

Antihypertensives come from several different drug classes. Beta blockers, like metoprolol, are only one option and are not preferred for blood pressure control alone. Nevertheless, they have their niche, particularly when other forms of heart disease are present. Deciding on the best choice for hypertension treatment is complex, so a detailed conversation with your healthcare provider is essential when comparing metoprolol and the alternatives.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Lopressor (metoprolol tartrate) is a brand-name medication in a well-known drug class called beta blockers. It is approved by the Food and Drug Administration (FDA) for use in the management of several cardiovascular conditions, including high blood pressure (hypertension), chest pain (angina), and myocardial infarction (MI, or a heart attack). Off-label use occurs in the […]<\/p>\n","protected":false},"author":133,"featured_media":50860,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9650,790,737],"coauthors":[10869],"class_list":["post-50856","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-blood-thinners","tag-chronic-disease","tag-heart-health","wpautop"],"acf":[],"yoast_head":"\nMetoprolol alternatives for blood pressure and heart conditions<\/title>\n<meta name=\"description\" content=\"Toprol XL, Coreg, Norvasc, and Zestril are some metoprolol alternatives for chest pain and regulating blood pressure. 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