{"id":51343,"date":"2022-05-25T09:14:31","date_gmt":"2022-05-25T13:14:31","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=51343"},"modified":"2026-04-03T13:02:19","modified_gmt":"2026-04-03T17:02:19","slug":"tresiba-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/tresiba-alternatives\/","title":{"rendered":"Tresiba alternatives: What can I take instead of Tresiba?"},"content":{"rendered":"

Tresiba<\/span><\/a> is an ultra-long-acting <\/span>basal insulin<\/span> that controls <\/span>blood sugar levels<\/span> in adults and pediatric patients 1 year of age and older with Type 1 and <\/span>Type 2<\/span> diabetes<\/span><\/a>. Injections can be administered with a FlexTouch Pen or using a standard syringe and needle. The insulin degludec delivery system in Tresiba makes it the longest-acting insulin available today, requiring only one injection daily to provide even glycemic control for up to 42 hours. If there are problems with Tresiba, people can use other long-acting insulins.\u00a0<\/span><\/p>\n

What can I take instead of <\/span>Tresiba<\/span>?<\/span><\/h2>\n

Tresiba may not be a good fit for everyone. Long-acting insulins can have serious side effects such as hypoglycemia (low blood sugar), weight gain, or allergic reactions. On the other hand, people may require a lower-cost basal insulin even with insurance coverage.\u00a0<\/span><\/p>\n

The chart below lists some alternative basal insulins that can be used to manage elevated glucose levels.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

Compare <\/span>Tresiba<\/span> alternatives<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Tresiba<\/span><\/a> (<\/span>insulin degludec<\/span><\/a>)<\/span><\/td>\n$445 for 1, 10 mL of 100 units\/mL vial<\/span><\/td>\n$94 for 1, 10 mL of 100 units\/mL vial at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Toujeo<\/span><\/a> (<\/span>insulin glargine SoloStar<\/span><\/a>)<\/span><\/td>\n$177 for 1, 1.5 mL of 300 units\/mL injection pen<\/span><\/td>\n$43 for 1, 1.5 mL of 300 units\/mL injection pen at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Basaglar<\/span><\/a> (<\/span>insulin glargine<\/span>)<\/span><\/td>\n$94 for 1, 3 mL of 100 units\/mL injection pen<\/span><\/td>\n$54 per 1, 3 mL of 100 units\/mL injection pens at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Lantus<\/span><\/a> (<\/span>insulin glargine<\/span>)<\/span><\/td>\n$80 for 1, 3 mL of 100 units\/mL injection pen<\/span><\/td>\n$21 for 1, 3 mL of 100 units\/mL injection pens at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Semglee<\/span><\/a> (<\/span>insulin glargine-ygfn<\/span><\/a>)<\/span><\/td>\n$112 for 1, 3 mL of 100 units\/mL injection pen<\/span><\/td>\n$20 for 1, 3 mL of 100 units\/mL injection pen at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Soliqua<\/span><\/a> 100\/33 (<\/span>insulin glargine<\/span>\/lixisenatide)<\/span><\/td>\n$1,171 for 5, 3 mL of 100 units-33 mcg\/mL injection pens<\/span><\/td>\n$774 for 5, 3 mL of 100 units-33 mcg\/mL injection pens at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Xultophy<\/span><\/a> 100\/3.6 (<\/span>insulin degludec<\/span>\/liraglutide)<\/span><\/td>\n$543 for 1, 3 mL of 100 units-3.6 mg\/mL injection pen<\/span><\/td>\n$238 for 1, 3 mL of 100 units-3.6 mg\/mL injection pens at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a>\u00a0<\/b><\/td>\n<\/tr>\n
Humalog* insulin for pump (pump supply costs are separate)<\/span><\/td>\n$116 for 1, 3 mL vials of 100 units\/mL<\/span><\/td>\n$33 for 1, 10 mL vials of 100 units\/mL at Kroger or Harris Teeter<\/span><\/td>\nSee latest prices<\/span><\/a>\u00a0<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of April 3, 2026. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under \u201cSavings options\u201d to see the latest drug prices.<\/span><\/i><\/small><\/small><\/p>\n

*Fast-acting insulins (such as Humalog or Novolog) are commonly used in insulin pumps. With this system, the same insulin provides both basal insulin (continuous tiny doses) and mealtime insulin (bolus doses). See the section below for more information.\u00a0<\/span><\/p>\n

Top 5 <\/span>Tresiba<\/span> alternatives<\/span><\/h2>\n

2. Basaglar<\/span><\/h3>\n

Basaglar<\/span><\/a> (insulin glargine) is a <\/span>long-acting insulin<\/span> analog with a duration of action of 24 hours, so most patients require only one injection daily. This <\/span>type of insulin<\/span> can be used in adults with Type 1 or Type 2<\/span> diabetes<\/span>. It can also be used in children at least 6 years old with Type 1<\/span> diabetes<\/span>. When using <\/span>Basaglar<\/span> for Type 1<\/span> diabetes<\/span>, it is typically used along with a<\/span> fast-acting <\/span>insulin such as Humalog. <\/span>Basaglar<\/span> is injected under the skin like most insulins, but cannot be used in an insulin pump.<\/span><\/p>\n

3. Lantus<\/span>\u00a0<\/span><\/h3>\n

The <\/span>long-acting insulins,<\/span> Lantus<\/span> and <\/span>Lantus<\/span> SoloStar<\/span><\/a> (insulin glargine), are used for <\/span>glycemic control<\/span> in adults with Type 1 and Type 2<\/span> diabetes<\/span>. Lantus also treats pediatric Type 1<\/span> diabetes<\/span> for children 6 and older. <\/span>Lantus<\/span> is a daily <\/span>subcutaneous<\/span> injection with a 24-hour duration of action. <\/span>Short-acting<\/span> insulins must be combined with <\/span>Lantus<\/span> if Type 1<\/span> diabetes<\/span> is being managed. As with other long-acting insulins, Lantus is never used in an insulin pump.<\/span><\/p>\n

RELATED: <\/b>Lantus<\/b> side effects and how to avoid them<\/b><\/a><\/p>\n

4. Semglee<\/span><\/h3>\n

Semglee is a <\/span>long-acting insulin<\/span> used to manage diabetes in adults and children. It begins working two to four hours after injection and works evenly for about 24 hours. It is never used in an insulin pump. As with other long-acting insulins, patients must also inject fast-acting insulins at mealtime. Semglee is available as a prefilled pen or 100-unit vials for use with a syringe and needle.<\/span><\/p>\n

5. Insulin pump with Novolog or Humalog<\/span><\/h3>\n

Another alternative to consider is switching to an insulin pump rather than multiple daily injections (MDI). People on MDI typically inject a basal insulin once daily, as well as a fast-acting insulin for meals and to correct high blood sugars. An insulin pump delivers only one type of insulin, a fast-acting insulin such as Novolog or Humalog, in tiny doses throughout the day, which serves as a basal insulin. The pump communicates with your continuous glucose monitor (like Dexcom) to help make treatment decisions. For example, when your blood sugar is high, it can administer extra insulin. Or, when your blood sugar is dropping too low, it can temporarily pause insulin delivery. The pump can also administer insulin before meals. Some people prefer MDIs, while others prefer a pump. It is definitely worth a conversation with your healthcare provider so you can weigh the pros and cons.<\/span><\/p>\n

Natural alternatives to <\/span>Tresiba<\/span><\/h2>\n

When a new <\/span>diagnosis<\/span><\/a> of diabetes occurs, some patients may consider a more <\/span>natural approach<\/span><\/a> to lower <\/span>blood sugar levels<\/span>. Proper diet and <\/span>exercise<\/span><\/a> are integral parts of the treatment plan for Type 2<\/span> diabetes mellitus<\/span>, but they do not replace treatment recommended by your healthcare provider.\u00a0<\/span><\/p>\n

Some studies have shown that certain supplements may help manage blood sugar levels. However, the <\/span>American Diabetes Association<\/span><\/a> notes that supplements are not proven to be effective for lowering blood sugar or supporting diabetes management. Certain people, such as those who follow restrictive diets, older adults, and pregnant or breastfeeding women, may require a multivitamin. Always check with your healthcare provider for medical advice and remember that a multivitamin or supplement does not replace your recommended treatment.<\/span><\/p>\n

How to switch to a <\/span>Tresiba<\/span> alternative<\/span><\/h2>\n

If <\/span>Tresiba<\/span> has not met your expectations, it may be time to switch to another basal insulin or, for people with Type 2 diabetes, to a non-insulin medication like <\/span>Ozempic<\/span><\/a> (semaglutide). This should be done only under the guidance of your <\/span>healthcare<\/span> provider. Insulin dosages are usually calculated based on your specific needs, so your provider will need to help you transition to something else.\u00a0<\/span><\/p>\n

If <\/span>Tresiba<\/span> is stopped abruptly without a replacement antidiabetic medication, this may cause extremely high <\/span>blood sugar levels,<\/span> which may lead to diabetic ketoacidosis or other health complications. No matter what <\/span>type of insulin<\/span> you and your <\/span>healthcare<\/span> provider may decide on to manage your diabetes, cost savings should always be explored with SingleCare\u2019s <\/span>prescription discount coupons<\/span><\/a>.<\/span><\/p>\n

RELATED: <\/b>How much is Tresiba without insurance?<\/b><\/a><\/p>\n

Choosing the right path for diabetes treatment<\/span><\/h2>\n

Basal insulins are needed when fasting glucose levels are high, a condition typical of Type 1 diabetes, and in certain people with Type 2 diabetes. Choosing the right type of basal insulin depends on many factors, including lifestyle and insulin compliance. However, the most important factor is fasting blood glucose levels. Tresiba may be the most successful long-acting insulin at controlling fasting glucose levels in some people, but other long-acting or intermediate insulins like Lantus, Toujeo, Semglee, or an insulin pump may provide better glycemic control in other people. Always review your blood glucose levels, diabetes symptoms, and lifestyle needs with your healthcare provider to determine the best type of insulin for you.<\/span><\/p>\n

Lea este art\u00edculo en espa\u00f1ol aqu\u00ed.<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Tresiba is an ultra-long-acting basal insulin that controls blood sugar levels in adults and pediatric patients 1 year of age and older with Type 1 and Type 2 diabetes. Injections can be administered with a FlexTouch Pen or using a standard syringe and needle. The insulin degludec delivery system in Tresiba makes it the longest-acting […]<\/p>\n","protected":false},"author":15,"featured_media":51358,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,4350],"coauthors":[8861],"class_list":["post-51343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"\nTresiba alternatives: What can I take instead of Tresiba?<\/title>\n<meta name=\"description\" content=\"Basaglar, Lantus, Novolin, and Toujeo are some Tresiba alternatives. 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1. Toujeo<\/span>\u00a0<\/span><\/h3>\n

Toujeo<\/span><\/a> (insulin glargine U-300) is another ultra-<\/span>long-acting insulin<\/span> used for the management of Type 1 diabetes in both adults and children as young as 6 years old and Type 2 diabetes in adults. <\/span>Toujeo<\/span> begins to work a few hours after administration and works evenly for up to 36 hours. Only one injection daily is needed, but patients may also need to inject mealtime insulin at appropriate times.\u00a0<\/span><\/p>\n