{"id":51585,"date":"2022-06-15T13:30:20","date_gmt":"2022-06-15T17:30:20","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=51585"},"modified":"2026-03-09T15:45:51","modified_gmt":"2026-03-09T19:45:51","slug":"otezla-without-insurance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/otezla-without-insurance\/","title":{"rendered":"How much is Otezla without insurance?"},"content":{"rendered":"

Otezla (apremilast)<\/span><\/a> is a disease-modifying anti-rheumatic drug (DMARD) that helps reduce symptoms of autoimmune conditions, such as psoriatic arthritis, moderate-to-severe <\/span>plaque psoriasis<\/span><\/a>, and oral ulcers due to Beh\u00e7et’s disease, by blocking the immune system. It is an expensive brand-name drug with no generic or over-the-counter versions, but people without health insurance do have options that can help make treatment more affordable.<\/span><\/p>\n

RELATED: <\/b>What is Otezla?<\/b><\/a><\/p>\n

Is Otezla covered by insurance?<\/span><\/h2>\n

Many commercial health insurance plans cover Otezla but may require <\/span>prior authorization<\/span><\/a>, step therapy, and quantity limits. According to the manufacturer, Amgen, 99% of people with <\/span>private insurance have coverage for Otezla<\/span><\/a>.\u00a0<\/span><\/p>\n

People on Medicare plans, Medicaid, or Tricare are less likely to have Otezla coverage and are encouraged to contact Amgen for assistance. Insurance companies will require a specialty pharmacy to fill the prescription.<\/span><\/p>\n

How much does Otezla cost without insurance?<\/span><\/h2>\n

The average cost for a 30-day supply of Otezla tablets (60, 30 mg tablets) is $6,843 for people paying the full retail price. A year of treatment could cost almost $80,000. Insurance can reduce that cost, but the copay and other costs may still be high.\u00a0<\/span><\/p>\n

Even with insurance coverage, the out-of-pocket cost may be high. Insurance providers typically place Otezla in their highest copay tier for preferred brand-name specialty drugs. Not only will the co-payment cost be high, but there may be other fees, such as deductibles or coinsurance. An Otezla copay card can reduce the cost to $0 for people with private insurance, but it won\u2019t work with Medicare, Medicaid, or other government-subsidized health plans.<\/span><\/p>\n

People who can\u2019t afford Otezla may be able to afford other, more <\/span>traditional FDA-approved DMARDs<\/span><\/a>. For moderate to severe psoriatic arthritis, the <\/span>most commonly used traditional DMARDs<\/span><\/a> are methotrexate, cyclosporine, Azulfidine (sulfasalazine), Arava (leflunomide), and Azasan (azathioprine). However, they may not be as effective as Otezla for some people, and the side effects may differ.<\/span><\/p>\n

RELATED: <\/b>Otezla side effects<\/b><\/a><\/p>\n

How much does generic Otezla cost?<\/span><\/h3>\n

There are no generic versions of Otezla, but a generic option should be <\/span>available in the U.S.<\/span><\/a> by 2028.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
Drug name<\/b><\/td>\nPrice without insurance of a brand-name drug\u00a0<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Otezla (apremilast)<\/span><\/td>\n$6,843 per 60, 30 mg tablets\u00a0<\/span><\/td>\n$5,134 per 60, 30 mg tablets of brand-name Otezla at Kroger<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Trexall (methotrexate)<\/span><\/td>\n$217 for 4, 10 mg tablets<\/span><\/td>\n$12 for 24, 2.5 mg tablets of generic Trexall at Walmart<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Neoral (cyclosporine)<\/span><\/td>\n$391 per 30, 100 mg capsules<\/span><\/td>\n$44 per 30, 100 mg capsules of generic Neoral at Walmart<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Acitretin<\/span><\/td>\n$1,159 per 30, 25 mg capsules\u00a0<\/span><\/td>\n$96 per 30, 25 mg capsules of generic acitretin at CVS<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Azulfidine (sulfasalazine)<\/span><\/td>\n$232 per 120, 500 mg tablets<\/span><\/td>\n$20 per 120, 500 mg tablets of generic Azulfidine at Publix<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Arava\u00a0<\/span><\/p>\n

(leflunomide)<\/span><\/td>\n

$1,777 per 30, 20 mg tablets<\/span><\/td>\n$21 per 30, 20 mg tablets of generic Arava at Food Lion<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n
Azasan (azathioprine)<\/span><\/td>\n$343 per 30, 100 mg tablets<\/span><\/td>\n$63 per 30, 100 mg tablets of generic Azasan at CVS<\/span><\/td>\nSee updated prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of 02\/23\/2026. The listed price, without insurance, refers to the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available.<\/span><\/i><\/p>\n

RELATED: <\/b>What can I take instead of Otezla?<\/b><\/a><\/p>\n

Otezla costs by dose<\/span><\/h2>\n

As with other premium-priced brand-name medications, the retail price of Otezla does not vary by <\/span>dosage strength<\/span><\/a>. Drugs like Otezla that are sold through specialty pharmacies are generally not available in large quantities, such as a 90-day supply.\u00a0<\/span><\/p>\n\n\n\n\n\n\n\n\n
\n

Compare Otezla prices by strength<\/span><\/h3>\n

(per 60 tablets)<\/p>\n<\/th>\n<\/tr>\n<\/thead>\n

Strength<\/b><\/td>\nSingleCare price of brand-name Otezla<\/b><\/td>\n<\/tr>\n
20 mg of Otezla<\/span><\/td>\n$5,046 at Kroger<\/span><\/td>\n<\/tr>\n
30 mg of Otezla<\/span><\/td>\n$5,134 at Kroger<\/span><\/td>\n<\/tr>\n
See our lowest price for Otezla without insurance<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of 02\/23\/2026. Click the link under \u201cSee our lowest price\u201d to see the latest drug prices.<\/span><\/i><\/p>\n

How to get Otezla covered by insurance<\/span><\/h2>\n

When insurance companies deny Otezla coverage, it\u2019s typically because the prior authorization requirements haven’t been met. Doctors usually file all the prior authorization paperwork necessary when prescribing Otezla, along with other required paperwork, such as a form to be faxed to the specialty pharmacy filling the prescription.<\/span><\/p>\n

The first step after a denial of coverage is to talk to an insurance plan representative or the prescribing healthcare provider. The only options are to fulfill the prior authorization requirements, such as taking certain drugs for a limited time, or to appeal the decision. The prescribing clinician will have to submit the necessary paperwork demonstrating medical necessity.<\/span><\/p>\n

For plaque psoriasis, some insurance companies require a minimum amount of skin area affected before approving the drug. Called \u201cbody surface area requirements,\u201d they may be the reason coverage is denied. If so, talk to the prescribing healthcare provider about filing an appeal.<\/span><\/p>\n

How to get Otezla without insurance<\/span><\/h2>\n

With an annual cost of close to $80,000, Otezla may be hard to fit into most people\u2019s budgets without some outside help. Health insurance helps, but not everyone with insurance will have their claim readily approved. Patient assistance programs and manufacturer coupons can help people who meet the eligibility requirements, but not everyone is eligible. There are, however, several more surefire ways to make Otezla affordable, starting with a SingleCare <\/span>prescription discount card<\/span><\/a>.<\/span><\/p>\n

1. Use a SingleCare savings card<\/span><\/h3>\n

With a <\/span>free SingleCare coupon<\/span><\/a>, people can save up to $1,700 off the average retail price of Otezla. <\/span>Use SingleCare to compare Otezla prices near you<\/span><\/a>. Prescription prices vary by pharmacy. You may save hundreds of dollars on Otezla simply by switching pharmacies. Although registration is optional, you can <\/span>sign up for SingleCare to start earning additional savings<\/span><\/a> on future refills of Otzela or other medications.\u00a0<\/span><\/p>\n

2. Ask for a free Otezla starter pack from the prescriber<\/span><\/h3>\n

The prescribing healthcare provider or the pharmacy could provide a <\/span>free Otezla starter pack<\/span><\/a> containing the appropriate doses for the first 14 days of treatment. Fourteen days doesn\u2019t sound like much, but it does represent almost $3,000 in savings. It also provides a chance to explore other options.<\/span><\/p>\n

3. Get medical advice about switching to traditional DMARDs<\/span><\/h3>\n

If funding cannot be found, it may be necessary to switch to lower-cost generic drugs. Called \u201ctraditional DMARDs\u201d by healthcare professionals, these drugs are more affordable, and it\u2019s easier to find help paying for them. Although there may be trade-offs, as their side effects can differ and they may not be as effective as Otezla. Discuss these trade-offs and safety information with a healthcare professional before giving up on Otezla.<\/span><\/p>\n

The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of 02\/23\/2026. Prices vary by pharmacy. Visit our <\/span><\/i>Otezla coupon page<\/span><\/i><\/a> for the latest Otezla prices near you.<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"

Otezla (apremilast) is a disease-modifying anti-rheumatic drug (DMARD) that helps reduce symptoms of autoimmune conditions, such as psoriatic arthritis, moderate-to-severe plaque psoriasis, and oral ulcers due to Beh\u00e7et’s disease, by blocking the immune system. It is an expensive brand-name drug with no generic or over-the-counter versions, but people without health insurance do have options that […]<\/p>\n","protected":false},"author":15,"featured_media":52090,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[15103,608,4350],"coauthors":[8861],"class_list":["post-51585","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-pricing","tag-health-insurance","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"\nHow much does Otezla cost without insurance?<\/title>\n<meta name=\"description\" content=\"Otezla costs $114 per tablet, or $6,843 per month for 60, 30 mg tablets without insurance. 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