{"id":51933,"date":"2022-06-08T09:30:32","date_gmt":"2022-06-08T13:30:32","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=51933"},"modified":"2025-07-01T16:43:14","modified_gmt":"2025-07-01T20:43:14","slug":"vyvanse-and-caffeine","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/vyvanse-and-caffeine\/","title":{"rendered":"Is it safe to drink coffee if you\u2019re taking Vyvanse?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Whenever your healthcare provider prescribes a new medication, you should make sure you know how to take it safely. That means asking about possible interactions with other pills you take\u2014along with any food and drinks to avoid, including your daily coffee. Certain medications don\u2019t mix well with caffeine, especially <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/cns-stimulants\"><span style=\"font-weight: 400;\">stimulants<\/span><\/a><span style=\"font-weight: 400;\"> like Vyvanse.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse\/what-is\"><span style=\"font-weight: 400;\">Vyvanse<\/span><\/a><span style=\"font-weight: 400;\"> treats attention deficit hyperactivity disorder (ADHD) and binge eating disorder. Healthcare providers usually prescribe Vyvanse to be taken once every morning, which may be a problem if you also drink coffee in the morning. <\/span><span style=\"font-weight: 400;\">Before taking your first dose<\/span><span style=\"font-weight: 400;\">, be sure to ask your healthcare provider about any possible caffeine and Vyvanse interactions.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Vyvanse with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tVyvanse 30 mg (30 Capsules)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-cvs.svg\" alt=\"CVS Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$63.46<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/walgreens-logo.svg\" alt=\"Walgreens\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$121.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse#blog-cta\" class=\"coupon-see-all-btn\">See Vyvanse prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"does-vyvanse-have-caffeine-in-it\"><span style=\"font-weight: 400;\">Does Vyvanse have caffeine in it?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Vyvanse does not contain caffeine. Lisdexamfetamine dimesylate is the active ingredient in Vyvanse. Inactive ingredients include microcrystalline cellulose, croscarmellose sodium, and magnesium stearate, according to the <\/span><span style=\"font-weight: 400;\">FDA drug label<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"does-caffeine-affect-vyvanse\"><span style=\"font-weight: 400;\">Does caffeine affect Vyvanse?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">According to a <a href=\"https:\/\/www.ncausa.org\/Market-Research\/National-Coffee-Data-Trends\">2025 survey<\/a> by the National Coffee Association, 66% of Americans drink coffee every single day. And if you\u2019re a coffee drinker, studies show you\u2019re probably downing about three cups of joe per day. In other words, it\u2019s likely you\u2019re drinking caffeine regularly.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So what does that mean if your provider prescribes Vyvanse? <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/vyvanse\"><span style=\"font-weight: 400;\">Vyvanse (lisdexamfetamine dimesylate)<\/span><\/a><span style=\"font-weight: 400;\"> is a stimulant that acts on your central nervous system. Like Vyvanse, caffeine is also a stimulant. I<\/span><span style=\"font-weight: 400;\">n fact, many people with ADHD tend to use \u201csignificant amounts of caffeine\u201d prior to seeking treatment or being prescribed Vyvanse in order to keep themselves awake and alert.<\/span><span style=\"font-weight: 400;\"> However, caffeine doesn\u2019t help them with the core aspects of focus that are impaired with ADHD, says <\/span><a href=\"https:\/\/www.mindpath.com\/staff\/brian-zachariah-md\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Brian Zachariah<\/span><\/a><span style=\"font-weight: 400;\">, MD, a psychiatrist with Mindpath Health in Sugarland, Texas.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cCaffeine consumption and stimulant treatment is a very important discussion every provider should be having with their patients,\u201d Dr. Zachariah says.<\/span><\/p>\n<h2 id=\"can-you-drink-coffee-on-vyvanse\"><span style=\"font-weight: 400;\">Can you drink coffee on Vyvanse?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The good news is that you don\u2019t have to give up coffee altogether if you need to take Vyvanse, but you should probably cut back. \u201cCaffeine and Vyvanse can be consumed at the same time,\u201d Dr. Zachariah says. \u201cIt is not a one size fits all approach.\u201d The key is timing and moderation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When you first start taking Vyvanse, it\u2019s a good idea to hold off on the caffeinated beverages until you reach a point where the medication is therapeutic (that is, it\u2019s helping eliminate your symptoms). Then you can slowly reintroduce the caffeine and see how you do. Start with a small amount, to see how the combination affects you. Moderation is different for everyone. What\u2019s right for you may differ from what\u2019s right for someone else.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Psychiatric nurse practitioner <\/span><a href=\"https:\/\/www.rootedpsychiatry.com\/about\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alysha Woods<\/span><\/a><span style=\"font-weight: 400;\">, PMHNP-BC, uses several pieces of information when deciding what to advise her patients about Vyvanse and caffeine:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The amount of caffeine\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The dose of Vyvanse<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The patient\u2019s medical history<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u201cThe interaction with Vyvanse and caffeine is typically seen with higher amounts of caffeine ingestion but avoiding caffeine overall would be the safest way to use Vyvanse,\u201d says <\/span><a href=\"https:\/\/www.mytoolboxgenomics.com\/about-us\/erika-gray\/\"><span style=\"font-weight: 400;\">Erika Gray<\/span><\/a><span style=\"font-weight: 400;\">, Pharm.D., chief medical officer and co-founder of Toolbox Genomics, a DNA and epigenetic testing company. If that strikes terror in your coffee-loving heart, though, you could try to cut back on your caffeine consumption and see if that helps. For example, you could limit yourself to one cup of caffeinated coffee each day and substitute decaf the rest of the time. Avoid highly potent caffeine sources, such as energy drinks or caffeine pills.\u00a0<\/span><\/p>\n<h2 id=\"side-effects-of-vyvanse-and-caffeine\"><span style=\"font-weight: 400;\">Side effects of Vyvanse and caffeine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Does coffee make Vyvanse less effective? Caffeine and Vyvanse have a synergistic effect. Meaning, they can increase each other\u2019s effects. According to Dr. Gray, when taken together, caffeine and Vyvanse can increase the risk of issues such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irritability<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nervousness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart palpitations<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble sleeping<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These side effects are akin to taking <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/signs-vyvanse-dose-too-high\/\"><span style=\"font-weight: 400;\">too high a dosage of Vyvanse<\/span><\/a><span style=\"font-weight: 400;\"> or consuming too much caffeine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Two of the biggest risks of using Vyvanse and caffeine together are an increased heart rate and high blood pressure, Woods notes. Especially for people with a family or personal history of heart disease or circulatory issues, mixing Vyvanse and caffeine could pose a cardiovascular risk. Although rare, stimulants may carry a risk of triggering psychosis or mania, particularly in people who have a history of psychosis or mania. \u201cFor this reason, this is a conversation that each person should have with their mental health or medical provider,\u201d Woods says. \u201cGenerally, I work with patients on lessening the use of caffeine when I prescribe Vyvanse.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Gray also cautions that <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/vyvanse-side-effects-in-children\/\"><span style=\"font-weight: 400;\">children are more sensitive to the effects of stimulants<\/span><\/a><span style=\"font-weight: 400;\">. \u201cMany teenagers drink caffeine without their parents\u2019 knowledge,\u201d Woods explains. \u201cIt\u2019s important to remind children who take Vyvanse that they need to be especially careful if they decide to buy a sugary coffee drink.\u201d<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/vyvanse-side-effects\/\"><b>Vyvanse side effects<\/b><\/a><\/p>\n<h2 id=\"best-practices-for-taking-vyvanse\"><span style=\"font-weight: 400;\">Best practices for taking Vyvanse<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Caffeine isn\u2019t the only substance to be mindful about when you\u2019re taking Vyvanse. Here are a few other substances to be mindful of if you\u2019re on this particular medication:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Vitamin C:<\/b><span style=\"font-weight: 400;\"> \u201cIf patients are taking vitamin C supplements, they should separate the time they take the vitamin by at least one hour before and one hour after taking Vyvanse,\u201d Dr. Gray says. Vitamin C, or ascorbic acid, may decrease the blood levels and effectiveness of Vyvanse.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Acidic foods: <\/b><span style=\"font-weight: 400;\">Watch out for acidic foods like tomatoes, citrus fruits, grapes, and plums. Wait an hour before or after consuming those foods for taking your Vyvanse, says Dr. Gray. Like vitamin C, acidic foods can affect how your body absorbs the medication and may decrease the effectiveness of Vyvanse.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Alkalinizing agents. <\/b><span style=\"font-weight: 400;\">Certain drugs and substances act as alkalinizing agents, which cause the opposite effect of acidic agents when combined with Vyvanse. Urinary alkalinizing agents, such as acetazolamide and methazolamide, can increase blood levels and potential side effects of Vyvanse. Antacids, such as sodium bicarbonate, are also alkalinizing agents.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Antidepressants:<\/b><span style=\"font-weight: 400;\"> \u201cVyvanse may have interactions with some medications that are used for depression,\u201d cautions Dr. Gray. You shouldn\u2019t take Vyvanse if you\u2019re also taking an antidepressant in the category of <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/maois\"><span style=\"font-weight: 400;\">monoamine oxidase inhibitors (MAOIs)<\/span><\/a><span style=\"font-weight: 400;\">, and you may want to be careful about <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitors (SSRIs)<\/span><\/a><span style=\"font-weight: 400;\">. Taking Vyvanse with drugs that increase serotonin levels may increase the risk of serotonin syndrome.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ultimately, your best bet is to take any medication, including Vyvanse, exactly as prescribed\u2013and to ask your provider if you\u2019re uncertain about anything. And if you develop any new or concerning symptoms, definitely let your healthcare team know.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Whenever your healthcare provider prescribes a new medication, you should make sure you know how to take it safely. That means asking about possible interactions with other pills you take\u2014along with any food and drinks to avoid, including your daily coffee. Certain medications don\u2019t mix well with caffeine, especially stimulants like Vyvanse.\u00a0 Vyvanse treats attention [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":51566,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,12752,8905],"coauthors":[9482],"class_list":["post-51933","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-medication-side-effects","tag-seasonal","franchise-the-jolt","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Do Vyvanse and caffeine mix?<\/title>\n<meta name=\"description\" content=\"Combining Vyvanse and coffee can increase side effects of Vyvanse and caffeine like irritability, nervousness, 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