{"id":51948,"date":"2022-06-09T18:16:30","date_gmt":"2022-06-09T22:16:30","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=51948"},"modified":"2026-03-17T09:57:58","modified_gmt":"2026-03-17T13:57:58","slug":"eliquis-and-tylenol","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/eliquis-and-tylenol\/","title":{"rendered":"Can you take Eliquis and Tylenol together?"},"content":{"rendered":"

Eliquis<\/span><\/a> (apixaban) is a brand-name medication called a Factor Xa Inhibitor that works as an <\/span>anti-clotting drug<\/span><\/a> to prevent and treat blood clots. Blood clots can travel to different parts of the body, including the legs and lungs, and increase the risk of stroke or embolism (blocking of an artery). These clots can form from abnormal heart rhythms (also called atrial fibrillation) or surgery. Different types of clots include stroke (a blood clot in the brain), deep vein thrombosis (DVT), and pulmonary embolism (PE).<\/span><\/p>\n

Tylenol is the brand name of acetaminophen. It is available over the counter as a pain reliever and fever reducer. <\/span>Tylenol<\/span><\/a> is available as an over-the-counter (OTC) and in a <\/span>variety of dosage types<\/span><\/a> (such as tablets, chewable tablets, softgels, gelcaps, and liquid) and formulations (such as regular strength, extra strength, and extended release). Tylenol can be used for various health conditions, including headache, backache, arthritis, toothache, fever, muscle aches, and menstrual cramps.<\/span><\/p>\n

People taking <\/span>Eliquis<\/span><\/a> may need pain relievers for general aches and pains or pain associated with surgery recovery. As an anti-clotting medication, Eliquis can thin the blood and increase the risk of bleeding. It\u2019s important for people to use pain relievers that do not cause dangerous <\/span>drug interactions with Eliquis<\/span> or further increase the risk of adverse effects like bleeding.<\/span><\/p>\n\t\t

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Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tEliquis 5 mg (28 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$155.92\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$155.92\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Eliquis prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

RELATED: <\/b>Eliquis alternatives: What can I take instead of Eliquis?<\/b><\/a>\u00a0<\/b><\/p>\n

Can you take Eliquis and Tylenol together?<\/span><\/h2>\n

Tylenol is a safe OTC pain reliever to take with Eliquis. There are no known <\/span>interactions<\/span><\/a> between Eliquis and Tylenol. Tylenol is not a blood thinner and does not further increase the risk of bleeding. Since Tylenol is also available as combination products, it\u2019s important to check if these products contain medicines that may interact with Eliquis. For example, Tylenol PM contains the sleep aid diphenhydramine in addition to acetaminophen and is safe to take with Eliquis.<\/span><\/p>\n

Eliquis and pain relievers<\/span><\/h2>\n

Like Tylenol PM, many combination products contain Tylenol\u2019s active ingredient, acetaminophen (also called paracetamol), and are safe to take with Eliquis. However, the combination products Advil Dual Action (acetaminophen and ibuprofen) and Excedrin (acetaminophen, aspirin, and caffeine)should be avoided with Eliquis due to the additional ingredients ibuprofen and aspirin, which can increase bleeding.\u00a0<\/span><\/p>\n

In general, Eliquis and other blood thinners like <\/span>Xarelto<\/span><\/a> (rivaroxaban), <\/span>Pradaxa<\/span><\/a> (dabigatran), Coumadin <\/span>(warfarin)<\/span><\/a>, and <\/span>heparin<\/span><\/a> should not be taken with <\/span>non-steroidal anti-inflammatory drugs (NSAIDs) <\/span><\/a>and certain antidepressants used for pain, such as <\/span>selective serotonin reuptake inhibitors (SSRIs)<\/span><\/a> or <\/span>serotonin norepinephrine reuptake inhibitors (SNRIs)<\/span><\/a>. These combinations should be avoided because NSAIDs and certain antidepressants can also increase the risk of bleeding by influencing how platelets work.<\/span><\/p>\n

While taking Eliquis, people may bruise more easily. However, some indicators of possible dangerous bleeding should be addressed immediately, as they can be serious side effects. People should call their healthcare provider or seek immediate medical attention with the following signs and symptoms:<\/span><\/p>\n