{"id":52223,"date":"2022-06-24T10:38:18","date_gmt":"2022-06-24T14:38:18","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=52223"},"modified":"2022-06-24T10:38:18","modified_gmt":"2022-06-24T14:38:18","slug":"sulfasalazine-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/sulfasalazine-alternatives\/","title":{"rendered":"Sulfasalazine alternatives: What can I take instead of sulfasalazine?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#compare-sulfasalazine-alternatives\"> Compare sulfasalazine alternatives<\/a> | <a href=\"#actemra\">Actemra<\/a> | <a href=\"#enbrel\">Enbrel<\/a> | <a href=\"#humira\">Humira<\/a> | <a href=\"#methotrexate\">Methotrexate<\/a> | <a href=\"#remicade\">Remicade<\/a> | <a href=\"#natural-alternatives\">Natural alternatives<\/a><\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you have <\/span><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">ulcerative colitis<\/span><span style=\"font-weight: 400;\">, you may have heard of a drug called <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Sulfasalazine<\/span><span style=\"font-weight: 400;\"> is the ingredient and generic version of the <\/span><span style=\"font-weight: 400;\">brand-name<\/span><span style=\"font-weight: 400;\"> prescription drug, <\/span><span style=\"font-weight: 400;\">Azulfidine<\/span><span style=\"font-weight: 400;\">, which is made by Pfizer. <\/span><span style=\"font-weight: 400;\">Sulfasalazine<\/span><span style=\"font-weight: 400;\"> is <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=ad13d598-7b1b-48d3-a25b-08635b419f99\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">used for the following conditions<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">To treat mild to moderate <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/ulcerative-colitis-vs-crohns\/\"><span style=\"font-weight: 400;\">ulcerative colitis<\/span><\/a><span style=\"font-weight: 400;\"> (UC), which is a type of <\/span><span style=\"font-weight: 400;\">inflammatory bowel disease<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">IBD<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">To treat severe UC, in combination with other medication(s)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">To lengthen the time between UC attacks (<\/span><span style=\"font-weight: 400;\">flare-ups<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Azulfidine EN-tabs<\/span><span style=\"font-weight: 400;\"> are another <\/span><span style=\"font-weight: 400;\">formulation<\/span><span style=\"font-weight: 400;\"> that contains <\/span><span style=\"font-weight: 400;\">delayed-release<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">enteric<\/span><span style=\"font-weight: 400;\">-coated <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Sulfasalazine<\/span> <span style=\"font-weight: 400;\">delayed-release<\/span><span style=\"font-weight: 400;\"> tablets can treat the conditions listed above. In addition, <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span> <span style=\"font-weight: 400;\">delayed-release<\/span><span style=\"font-weight: 400;\"> tablets can treat patients with <\/span><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><span style=\"font-weight: 400;\"> (RA) who have not responded to or cannot tolerate other medications. This drug can also treat children with polyarticular-course1 juvenile RA who have not responded to other medications.<\/span><\/p>\n<p><a href=\"https:\/\/www.rheumatology.org\/I-Am-A\/Patient-Caregiver\/Treatments\/Sulfasalazine-Azulfidine\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sulfasalazine<\/span><\/a><span style=\"font-weight: 400;\"> is part of a drug class called <\/span><span style=\"font-weight: 400;\">disease-modifying anti-rheumatic drugs<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">DMARDs<\/span><span style=\"font-weight: 400;\">), more specifically, it is an <\/span><span style=\"font-weight: 400;\">aminosalicylate<\/span><span style=\"font-weight: 400;\">. It works to treat these autoimmune conditions by decreasing inflammation in the body. It is approved by the <\/span><span style=\"font-weight: 400;\">U.S. Food and Drug Administration (<\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">).<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In some cases, patients may be looking for an alternative <\/span><span style=\"font-weight: 400;\">treatment option<\/span><span style=\"font-weight: 400;\"> to <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">. Some people may not have the desired effect and want to try a different medication to see if it works better. Others may have <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> that persist or are bothersome. <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/28405\/sulfasalazine\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal liver function tests<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Appetite loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood in the urine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Crystals in the urine which can cause stones or kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cyanosis (blue skin due to poor circulation)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hemolytic anemia (a condition where red blood cells are destroyed faster than they are made)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Leukopenia (low <\/span><span style=\"font-weight: 400;\">white blood cell<\/span><span style=\"font-weight: 400;\"> count, which can interfere with the body\u2019s ability to fight infection and increase the <\/span><span style=\"font-weight: 400;\">risk of infection<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low <\/span><span style=\"font-weight: 400;\">sperm count<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sensitivity to the sun<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash<\/span><span style=\"font-weight: 400;\">\/itching\/hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach problems like pain, nausea, vomiting, and indigestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling and sores in the mouth<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Or, a serious <\/span><span style=\"font-weight: 400;\">side effect<\/span><span style=\"font-weight: 400;\"> could occur, such as seizures, low blood sugar, infections, problems with the lungs, liver, kidneys, or pancreas, or severe or life-threatening <\/span><span style=\"font-weight: 400;\">allergic reactions<\/span><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/medlineplus.gov\/genetics\/condition\/stevens-johnson-syndrome-toxic-epidermal-necrolysis\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">skin reactions<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Some people cannot take <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> at all. According to the <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=ad13d598-7b1b-48d3-a25b-08635b419f99\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> is not approved for use in:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Patients with an intestinal or urinary blockage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Patients with a condition called <\/span><a href=\"https:\/\/www.niddk.nih.gov\/health-information\/liver-disease\/porphyria\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">porphyria<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Patients who are allergic to <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">, mesalamine, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sulfonamides\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">sulfa<\/span><span style=\"font-weight: 400;\"> drugs<\/span><\/a><span style=\"font-weight: 400;\">, or <\/span><span style=\"font-weight: 400;\">salicylates<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">If you are looking for a different medication, there are several alternatives to <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> that you can discuss with your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What can I take in place of <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are other options available to treat UC or RA symptoms that do not improve with <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">, or when <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> cannot be tolerated. The table below compares <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> (in bold), with common alternatives. All of the drugs listed are prescription medications that are approved by the <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"compare-sulfasalazine-alternatives\"><span class=\"title\">Compare sulfasalazine alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage<\/b><\/td>\n<td><b>Coupons<\/b><\/td>\n<\/tr>\n<tr>\n<td>Sulfasalazine<\/td>\n<td>Ulcerative colitis (UC)<\/p>\n<p>(Delayed-release can be used for UC and rheumatoid arthritis (RA)<\/td>\n<td>Varies; the maintenance dose for adults is 2 grams per day<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/sulfasalazine\">Sulfasalazine coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Actemra (tocilizumab) injection<\/td>\n<td>RA<\/p>\n<p>Giant cell arteritis<\/p>\n<p>Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)<\/p>\n<p>Polyarticular Juvenile Idiopathic Arthritis (PJIA)<\/p>\n<p>Systemic Juvenile Idiopathic Arthritis (SJIA)<\/p>\n<p>Cytokine Release Syndrome (CRS)<\/td>\n<td>Varies by indication<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/actemra\">Actemra coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Asacol (mesalamine) oral<\/td>\n<td>UC<\/td>\n<td>To treat active UC: two 400 mg tablets 3 times daily for 6 weeks<\/p>\n<p>To maintain remission of UC: 1.6 grams daily in divided doses<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/asacol-hd\">Asacol coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Celebrex (celecoxib) oral capsule<\/td>\n<td>Osteoarthritis (OA)<\/p>\n<p>RA<\/p>\n<p>Juvenile Rheumatoid Arthritis (JRA)<\/p>\n<p>Ankylosing Spondylitis (AS)<\/p>\n<p>Acute pain<\/p>\n<p>Primary dysmenorrhea<\/td>\n<td>Varies; for RA the dose is 100 or 200 mg by mouth twice daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/celebrex\">Celebrex\u00a0 coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Cimzia (certolizumab pegol) injection<\/td>\n<td>Crohn\u2019s disease<\/p>\n<p>RA<\/p>\n<p>Psoriatic arthritis<\/p>\n<p>AS<\/p>\n<p>Axial spondyloarthritis<\/p>\n<p>Plaque psoriasis<\/td>\n<td>Varies by indication. For RA: 400 mg initially and again at week 2 and week 4, then 200 mg every other week<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/cimzia\">More details<\/a><\/td>\n<\/tr>\n<tr>\n<td>Colazal (balsalazide) oral<\/td>\n<td>UC<\/td>\n<td>Adults: 2.25 g (three 750 mg capsules) three times daily for 8 to 12 weeks<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/colazal\">Colazal coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Enbrel (etanercept) injection<\/td>\n<td>RA<\/p>\n<p>JIA<\/p>\n<p>Psoriatic arthritis<\/p>\n<p>AS<\/p>\n<p>Plaque psoriasis<\/td>\n<td>Varies<\/p>\n<p>For RA: 50 mg once weekly with or without methotrexate<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/enbrel\">Enbrel coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Humira (adalimumab) injection<\/td>\n<td>RA<\/p>\n<p>Juvenile idiopathic arthritis (JIA)<\/p>\n<p>Psoriatic arthritis<\/p>\n<p>AS<\/p>\n<p>Crohn\u2019s disease<\/p>\n<p>Ulcerative colitis<\/p>\n<p>Plaque psoriasis<\/p>\n<p>Hidradenitis suppurativa (HS)<\/p>\n<p>Uveitis<\/td>\n<td>Varies by indication<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/humira\">Humira coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Imuran (azathioprine) oral<\/td>\n<td>RA<\/p>\n<p>Prevents rejection after kidney transplant<\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\">Off-label<\/a> for Crohn\u2019s disease\u00a0 or UC<\/td>\n<td>Varies by indication<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/imuran\">Imuran coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Lialda (mesalamine) oral<\/td>\n<td>UC<\/td>\n<td>Adults:<\/p>\n<p>To induce remission, the dose is 2.4 to 4.8 grams once daily<\/p>\n<p>To maintain remission, the dose is 2.4 grams once daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lialda\">Lialda coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Methotrexate injection or tablet<\/td>\n<td>RA<\/p>\n<p>PJIA<\/p>\n<p>Severe psoriasis<\/p>\n<p>Certain cancers<\/p>\n<p>Off-label for Crohn\u2019s disease<\/td>\n<td>Varies;<\/p>\n<p>For RA: 7.5 to 15 mg by mouth or injected weekly; given with folic acid or leucovorin<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/methotrexate\">Methotrexate coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Mobic (meloxicam) oral<\/td>\n<td>OA<\/p>\n<p>RA<\/p>\n<p>Juvenile Rheumatoid Arthritis (JRA) in patients who weigh \u226560 kg (132 lb)<\/td>\n<td>For RA: Starting dose is 7.5 mg once daily; may be increased to 15 mg once daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/meloxicam\">Meloxicam coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Plaquenil (hydroxychloroquine) oral<\/td>\n<td>RA<\/p>\n<p>Malaria<\/p>\n<p>Lupus<\/td>\n<td>RA: Initial dose is 400 to 600 mg daily<\/p>\n<p>Chronic dose is 200 mg once or twice daily or 400 mg once daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/plaquenil\">Plaquenil coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Prednisone oral (steroid)<\/td>\n<td>Many indications for various inflammatory conditions; including<\/p>\n<p>RA<\/p>\n<p>AS<\/p>\n<p>Psoriatic arthritis<\/td>\n<td>Varies; general dose is 5 to 60 mg daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\">Prednisone coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Remicade (infliximab) injection<\/td>\n<td>Crohn\u2019s disease<\/p>\n<p>UC<\/p>\n<p>RA (with methotrexate)<\/p>\n<p>AS<\/p>\n<p>Psoriatic arthritis<\/p>\n<p>Plaque psoriasis<\/td>\n<td>Varies by indication<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/remicade\">More details<\/a><\/td>\n<\/tr>\n<tr>\n<td>Rowasa (mesalamine) enema<\/td>\n<td>UC<\/p>\n<p>Proctosigmoiditis<\/p>\n<p>Proctitis<\/td>\n<td>One rectal instillation daily at bedtime, and retained for 8 hours; for about 3 to 6 weeks<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/rowasa\">Rowasa coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Stelara (ustekinumab) injection<\/td>\n<td>Crohn\u2019s disease<\/p>\n<p>UC<\/p>\n<p>Psoriatic arthritis<\/p>\n<p>Plaque psoriasis<\/td>\n<td>Varies by weight and indication<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/stelara\">More details<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400;\">Other alternatives to <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Apriso (mesalamine) oral: for UC<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Asacol HD (mesalamine) oral: for UC<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Delzicol (mesalamine) oral: for UC<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pentasa (mesalamine) oral: for UC<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Top 5 <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> alternatives<\/span><\/h2>\n<h3 id=\"actemra\"><span style=\"font-weight: 400;\">1. Actemra<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Actemra is an injection that contains the ingredient tocilizumab, which can be given intravenously (into a vein over a one-hour period) or subcutaneously (as an injection under the skin).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Actemra is in a drug class called interleukin-6 (IL-6) receptor antagonists. It is also known as a <\/span><a href=\"https:\/\/www.fda.gov\/about-fda\/center-biologics-evaluation-and-research-cber\/what-are-biologics-questions-and-answers\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">biologic<\/span><\/a><span style=\"font-weight: 400;\">. Actemra can be used for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with moderate to severe RA who have not responded to other medication(s)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with giant cell arteritis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with systemic sclerosis-associated interstitial lung disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Patients 2 years and older with polyarticular juvenile idiopathic arthritis or systemic juvenile idiopathic arthritis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults and children 2 years and older with cytokine release syndrome<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> of Actemra are headache, injection site reactions, high blood pressure, upper respiratory tract infections, common cold, and increased liver function tests.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Actemra has a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\">, which is the most serious warning required by the <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">. The warning states that Actemra can cause serious infections that can lead to hospitalization or death. These infections may include tuberculosis (TB), or other bacterial, viral, or fungal infections. If a serious infection occurs, Actemra should be stopped until the infection is controlled. Before starting Actemra, patients should be tested for TB, and treated if the test is positive. During treatment, patients should be monitored for TB.\u00a0<\/span><\/p>\n<h3 id=\"enbrel\"><span style=\"font-weight: 400;\">2. Enbrel<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/enbrel-vs-humira\/\"><span style=\"font-weight: 400;\">Enbrel<\/span><\/a><span style=\"font-weight: 400;\"> is an injection. It contains the ingredient etanercept, which is given subcutaneously every week.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Enbrel is in a drug class called tumor necrosis factor (TNF) blockers. It is also a <\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">Enbrel can be used for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/osteoarthritis-vs-rheumatoid-arthritis\/\"><span style=\"font-weight: 400;\">RA<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psoriatic arthritis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/ankylosing-spondylitis-diet\/\"><span style=\"font-weight: 400;\">Ankylosing spondylitis<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Plaque <\/span><span style=\"font-weight: 400;\">psoriasis<\/span><span style=\"font-weight: 400;\"> (adults and children 4 years and older)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Polyarticular juvenile idiopathic arthritis (in patients 2 years and older)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/enbrel-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of Enbrel<\/span><\/a><span style=\"font-weight: 400;\"> include injection site reactions and infections.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Enbrel has the same black box warning as Actemra. Additionally, the black box warning states that lymphoma and other malignancies (cancers), some of which have caused death, have occurred in children and adolescents who have taken TNF blockers.\u00a0<\/span><\/p>\n<h3 id=\"humira\"><span style=\"font-weight: 400;\">3. Humira<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Humira is an injection and contains the ingredient adalimumab, which is given subcutaneously every week or every two weeks.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Like Enbrel, <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=608d4f0d-b19f-46d3-749a-7159aa5f933d\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Humira<\/span><\/a><span style=\"font-weight: 400;\"> is in a drug class called tumor necrosis factor (TNF) blockers. It is also a <\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\">. Humira can be used for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe RA in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Juvenile idiopathic arthritis in patients 2 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psoriatic arthritis<\/span><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ankylosing spondylitis<\/span><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe <\/span><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> in adults and children 6 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe <\/span><span style=\"font-weight: 400;\">ulcerative colitis<\/span><span style=\"font-weight: 400;\"> in adults and children 5 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/blog\/biologics-for-psoriasis\/\"><span style=\"font-weight: 400;\">Plaque <\/span><span style=\"font-weight: 400;\">psoriasis<\/span><\/a><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Moderate to severe hidradenitis suppurativa in patients 12 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Uveitis in adults and children 2 years and older<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/humira-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of Humira<\/span><\/a><span style=\"font-weight: 400;\"> include injection site reactions, headache, rash, upper respiratory infections, and sinus infections.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Humira has the same black box warning as Enbrel. Additionally, the black box warning states that a rare type of T-cell lymphoma, called hepatosplenic T-cell lymphoma, has occurred in adolescents and young adults with <\/span><span style=\"font-weight: 400;\">inflammatory bowel disease<\/span><span style=\"font-weight: 400;\"> who were treated with TNF blockers.\u00a0<\/span><\/p>\n<h3 id=\"methotrexate\"><span style=\"font-weight: 400;\">4. <\/span><span style=\"font-weight: 400;\">Methotrexate<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Methotrexate<\/span><span style=\"font-weight: 400;\"> is available in both oral and injection forms.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Methotrexate<\/span><span style=\"font-weight: 400;\"> is in a drug class called dihydrofolate reductase inhibitors. Oral <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=d71b1856-99d8-4a9e-9189-f87b6675f80a#section-5.10\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">methotrexate<\/span><\/a><span style=\"font-weight: 400;\"> can be used for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults and children with acute lymphoblastic leukemia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with mycosis fungoides<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/hodgkins-vs-non-hodgkins\/\"><span style=\"font-weight: 400;\">non-Hodgkin lymphoma<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with RA<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adults with severe <\/span><span style=\"font-weight: 400;\">psoriasis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pediatric patients with polyarticular juvenile idiopathic arthritis (pJIA)<\/span><\/li>\n<\/ul>\n<p><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=dd035a9f-cd40-4314-b9d8-2294b8a924e2\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Injectable <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><\/a><span style=\"font-weight: 400;\"> can be used for RA, pJIA, <\/span><span style=\"font-weight: 400;\">psoriasis<\/span><span style=\"font-weight: 400;\">, and several times of cancers.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most <\/span><span style=\"font-weight: 400;\">common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/methotrexate-side-effects\/\"><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\"> side effects<\/span><\/a><span style=\"font-weight: 400;\"> are nausea, stomach problems, low <\/span><span style=\"font-weight: 400;\">white blood cells<\/span><span style=\"font-weight: 400;\">, and <\/span><span style=\"font-weight: 400;\">ulcers<\/span><span style=\"font-weight: 400;\"> in the mouth. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/folic-acid\/what-is\"><span style=\"font-weight: 400;\">Folic acid<\/span><\/a><span style=\"font-weight: 400;\"> supplementation<\/span><span style=\"font-weight: 400;\"> should be given to lower the risk of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> from <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Methotrexate<\/span><span style=\"font-weight: 400;\"> has a black box warning. This drug can harm an unborn baby, and may cause death. <\/span><span style=\"font-weight: 400;\">Methotrexate<\/span><span style=\"font-weight: 400;\"> should not be used for non-neoplastic (non-cancer) diseases in pregnant women. Women of childbearing age should be educated about the risk to an unborn baby and should speak to their <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> about using effective contraception. People who are allergic to <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\"> should not take this drug. <\/span><span style=\"font-weight: 400;\">Methotrexate<\/span><span style=\"font-weight: 400;\"> can cause serious reactions, including death. Patients who take this drug should be closely monitored for bone marrow, stomach, lungs, kidneys, skin, and <\/span><span style=\"font-weight: 400;\">liver problems<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"remicade\"><span style=\"font-weight: 400;\">5. Remicade<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Remicade is an injection that contains the ingredient infliximab, which is given intravenously every six to eight weeks, depending on the indication.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Remicade is a TNF blocker and a <\/span><span style=\"font-weight: 400;\">biologic<\/span><span style=\"font-weight: 400;\">. It can be used for:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><span style=\"font-weight: 400;\"> in adults and children 6 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ulcerative colitis<\/span><span style=\"font-weight: 400;\"> in adults and children 6 years and older<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">RA in adults (in combination with <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ankylosing spondylitis<\/span><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psoriatic arthritis<\/span><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Plaque <\/span><span style=\"font-weight: 400;\">psoriasis<\/span><span style=\"font-weight: 400;\"> in adults<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> of Remicade are headache, infusion-related reactions, upper respiratory tract infections, sinus infections, sore throat, and stomach pain<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Remicade has the same black box warning as Humira.\u00a0<\/span><\/p>\n<p><b>Related: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/remicade-vs-humira\/\"><b>Remicade vs. Humira<\/b><\/a><\/p>\n<h2 id=\"natural-alternatives\"><span style=\"font-weight: 400;\">Natural alternatives to <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you are experiencing RA, you may be wondering if there is a natural alternative to <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\">. While supplements do not replace prescription medications, there are some vitamins and supplements that may help improve symptoms. Before taking any vitamin or supplement, though, consult your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Folic acid<\/b><span style=\"font-weight: 400;\">: Many people who have RA take a drug called <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">, which can deplete folic acid levels. When taking <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">, supplementation with folic acid will be necessary. Folic acid will also help reduce some of the <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">methotrexate<\/span><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Calcium and vitamin D<\/b><span style=\"font-weight: 400;\">: It\u2019s important to get enough calcium and <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/vitamin-d-vs-d3\/\"><span style=\"font-weight: 400;\">vitamin D<\/span><\/a><span style=\"font-weight: 400;\"> if you have RA and you also have bone loss. <\/span><span style=\"font-weight: 400;\">Steroids<\/span><span style=\"font-weight: 400;\">, such as prednisone, which are sometimes prescribed for RA, can also cause bone loss, making it important to supplement with calcium and vitamin D. Your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> can look at the results of your <\/span><span style=\"font-weight: 400;\">blood tests<\/span><span style=\"font-weight: 400;\"> and recommend an appropriate dosage to take.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Omega-3 fatty acids (fish oil)<\/b><span style=\"font-weight: 400;\">: These supplements may help improve RA symptoms, such as joint pain, morning stiffness, and swollen joints.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>CBD<\/b><span style=\"font-weight: 400;\">: While it may be tempting to hop on the <\/span><a href=\"https:\/\/www.arthritis.org\/health-wellness\/healthy-living\/managing-pain\/pain-relief-solutions\/cbd-for-arthritis-pain\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">CBD<\/span><\/a><span style=\"font-weight: 400;\"> bandwagon, consult your <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\"> before trying this natural product. Although there are no clear guidelines on CBD and arthritis, medical experts with the <\/span><a href=\"https:\/\/www.arthritis.org\/about-us\/news-and-updates\/cbd\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Arthritis Foundation<\/span><\/a><span style=\"font-weight: 400;\"> remind patients that there is little data on CBD use in patients with arthritis. There are also potential <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\"> to be aware of. CBD, like other supplements, should never be used in place of prescription medicine. Patients who want to try CBD should start with a low dose, increasing slowly if needed. Patients should purchase CBD from a reputable business that has each batch evaluated for purity, safety, and potency by an independent lab, and has a certificate of analysis.<\/span><\/li>\n<\/ol>\n<p><span style=\"font-weight: 400;\">Again, <\/span><span style=\"font-weight: 400;\">these vitamins or supplements are not a substitute for medication, but rather a potential complement to the medication. Talk to your <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\"> about various natural methods you can try, in combination with your medications. Always check with your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> before trying an herbal supplement, as some may have <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\"> or dangerous adverse effects.\u00a0<\/span><\/p>\n<h2 id=\"how-to-switch-meds\"><span style=\"font-weight: 400;\">How to switch to a <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you are interested in switching to a <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> alternative, you can:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Contact your insurance provider if the price is a concern. Ask which <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> alternatives are covered in your formulary, and what the copay would be for each medication. Be sure to ask if your deductible has been met, or if you are still paying towards your deductible.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reach out to your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\">. You may be asked to make an appointment to talk about your medication regimen. You can review your medical conditions and history, and discuss alternative medications\u2014as well as potential <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\">\u2014with your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\">. If your provider decides to prescribe a <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> alternative, they can send the prescription to your pharmacy. Tell your pharmacist that you are switching from <\/span><span style=\"font-weight: 400;\">sulfasalazine<\/span><span style=\"font-weight: 400;\"> to the new medication, so they can update your file.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Search <\/span><a href=\"https:\/\/www.singlecare.com\/browse-prescriptions\"><span style=\"font-weight: 400;\">SingleCare<\/span><\/a><span style=\"font-weight: 400;\"> for coupons. SingleCare customers save up to 80% on prescription prices, and the coupons can be applied to refills, too.\u00a0\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Compare sulfasalazine alternatives | Actemra | Enbrel | Humira | Methotrexate | Remicade | Natural alternatives If you have rheumatoid arthritis or ulcerative colitis, you may have heard of a drug called sulfasalazine. Sulfasalazine is the ingredient and generic version of the brand-name prescription drug, Azulfidine, which is made by Pfizer. Sulfasalazine is used for [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":52244,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12164,790,16414,4350],"coauthors":[10668],"class_list":["post-52223","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-arthritis","tag-chronic-disease","tag-digestive-health","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top sulfasalazine alternatives and how to switch your Rx<\/title>\n<meta name=\"description\" content=\"Actemra, Enbrel, Humira, Methotrexate, and Remicade are some sulfasalazine alternatives. Get the full list here.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/sulfasalazine-alternatives\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sulfasalazine alternatives: What can I take instead of sulfasalazine?\" \/>\n<meta property=\"og:description\" content=\"Actemra, Enbrel, Humira, Methotrexate, and Remicade are some sulfasalazine alternatives. 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