{"id":52428,"date":"2022-07-06T15:20:08","date_gmt":"2022-07-06T19:20:08","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=52428"},"modified":"2026-03-01T18:59:54","modified_gmt":"2026-03-01T23:59:54","slug":"foods-to-avoid-with-eliquis","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/foods-to-avoid-with-eliquis\/","title":{"rendered":"What foods to avoid while on Eliquis"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/eliquis\"><span style=\"font-weight: 400;\">Eliquis<\/span><\/a><span style=\"font-weight: 400;\"> (apixaban) is a blood thinner that belongs to a class of medications called direct oral anticoagulants (DOACs). It is used to prevent and treat blood clots in patients with deep vein thrombosis (DVT), pulmonary embolism (PE), and nonvalvular atrial fibrillation (AFib), which is a type of irregular heartbeat that\u2019s not caused by a heart valve problem. Many people are aware of the blood thinner Coumadin (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/eliquis-vs-warfarin\/\"><span style=\"font-weight: 400;\">warfarin<\/span><\/a><span style=\"font-weight: 400;\">) and how certain foods need to be avoided while taking it. But what about the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/new-blood-thinners\/\"><span style=\"font-weight: 400;\">newer anticoagulants<\/span><\/a><span style=\"font-weight: 400;\">? Let\u2019s take a closer look at what foods to avoid while on Eliquis.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/conditions\/deep-vein-thrombosis-treatment-and-medications\"><b>DVT treatments and medications<\/b><\/a><\/p>\n<h2 id=\"how-eliquis-works\"><span style=\"font-weight: 400;\">How Eliquis works<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Eliquis works by blocking factor Xa (pronounced \u201cten-A\u201d), a factor in our blood that helps clots form. This is sometimes referred to as a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/factor-xa-inhibitors\"><span style=\"font-weight: 400;\">factor Xa inhibitor<\/span><\/a><span style=\"font-weight: 400;\">. There are many clotting factors in our blood, and factor Xa is one of the main ones.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Unlike the older blood thinner Coumadin (warfarin), Eliquis doesn\u2019t require monitoring of the international normalized ratio (INR), which is a process of regularly checking a person&#8217;s blood to ensure that it&#8217;s clotting within the desired range. Warfarin also belongs to a different class of medications called vitamin K antagonists, which work differently than DOACs like Eliquis.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Eliquis is prescribed in <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/eliquis\/dosage\"><span style=\"font-weight: 400;\">doses of 2.5 or 5 milligrams<\/span><\/a><span style=\"font-weight: 400;\"> to be taken twice a day. <\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Eliquis with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tEliquis 5 mg (60 Tablet)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$155.92<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$155.92<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/eliquis#blog-cta\" class=\"coupon-see-all-btn\">See Eliquis prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"foods-to-avoid-while-on-blood-thinners\"><span style=\"font-weight: 400;\">Foods to avoid while on blood thinners\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Eliquis doesn\u2019t work like other blood thinners, which have various food restrictions. For example, if you\u2019re taking warfarin, you need to be conscientious of how much vitamin K-containing foods you consume since <\/span><a href=\"https:\/\/www.pennmedicine.org\/updates\/blogs\/heart-and-vascular-blog\/2015\/june\/consistency-not-avoidance-the-truth-about-blood-thinners-leafy-greens-and-vitamin-k\"><span style=\"font-weight: 400;\">warfarin and Vitamin K<\/span><\/a><span style=\"font-weight: 400;\"> work against each other: Warfarin is a blood thinner, while Vitamin K helps blood clot. But that doesn\u2019t mean you should avoid foods rich in vitamin K entirely while on warfarin. It just means you need to consume a consistent amount of vitamin K-rich foods on a day-to-day basis so the body can maintain a healthy balance of both warfarin and Vitamin K. Examples of vitamin K-rich foods include spinach, broccoli, kale, and Brussels sprouts.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In contrast, apixaban (the active ingredient in Eliquis) does not rely on the vitamin K-dependent clotting pathway. Eliquis acts on clotting factor Xa and is unaffected by vitamin K intake. In fact, Eliquis has not been shown to have a bad interaction with any foods. The usual culprits when it comes to food-drug interactions, such as leafy green vegetables, grapefruit juice, cranberry juice, coffee, and peppermint tea, are safe to enjoy while taking Eliquis\u2014although some should be enjoyed in moderation.\u00a0<\/span><\/p>\n<h2 id=\"foods-to-avoid-or-limit-while-taking-eliquis\"><span style=\"font-weight: 400;\">Foods to avoid or limit while taking Eliquis<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Unlike other anticoagulants, Eliquis doesn\u2019t require you to avoid leafy greens. In fact, Eliquis doesn\u2019t have any dietary contraindications. However, certain citrus fruits prevent the breakdown of apixaban, meaning the drug stays in the body longer than it should and can increase the risk of bleeding and other side effects. While small amounts are generally okay, you should <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3589309\/\"><span style=\"font-weight: 400;\">limit your intake of the following<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Grapefruit and grapefruit juice<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Limes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pomelos<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Orange marmalade and Seville oranges (which are often used in marmalades)\u00a0<\/span><\/li>\n<\/ul>\n<h2 id=\"herbs-and-supplements-to-avoid-with-eliquis\"><span style=\"font-weight: 400;\">Herbs and supplements to avoid with Eliquis<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Since the Food and Drug Administration does not regulate herbals and supplements like other prescription medications, verifying potential interactions between herbal medications and prescription meds can be more difficult. It\u2019s always a good idea to seek medical advice from your healthcare provider before taking herbal or vitamin supplements. Not only can herbal medications interact with prescription meds, but they can also be dangerous if you have any liver or kidney problems.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There is some data that ginger, ginkgo biloba, turmeric, and some Chinese herbs can result in an increased risk of bleeding when combined with a blood-thinning medication such as apixaban. Additionally, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/st-johns-wort\/\"><span style=\"font-weight: 400;\">St. John&#8217;s wort<\/span><\/a><span style=\"font-weight: 400;\"> may decrease the effectiveness of apixaban.<\/span><\/p>\n<h2 id=\"medications-to-avoid-with-eliquis\"><span style=\"font-weight: 400;\">Medications to avoid with Eliquis<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It is also very important to be careful when taking medications like ibuprofen (Advil, Motrin), naproxen (Naprosyn), and diclofenac (Voltaren), which are collectively referred to as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">nonsteroidal anti-inflammatory drugs (NSAIDs)<\/span><\/a><span style=\"font-weight: 400;\">, while taking Eliquis. NSAIDs and aspirin will result in a higher risk of bleeding when combined with anticoagulants.<\/span><\/p>\n<h2 id=\"other-dietary-considerations-while-taking-eliquis\"><span style=\"font-weight: 400;\">Other dietary considerations while taking Eliquis<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many patients placed on Eliquis for the first time have underlying heart disease. As such, it is important to avoid red meat, fast foods, and refined sugars and instead choose <\/span><a href=\"https:\/\/www.health.harvard.edu\/heart-health\/heart-healthy-foods-what-to-eat-and-what-to-avoid\"><span style=\"font-weight: 400;\">heart-healthy foods<\/span><\/a><span style=\"font-weight: 400;\"> such as fruits and vegetables, whole grains, low-fat or nonfat dairy, healthy proteins, unsaturated fats and oils, and soluble fiber. Soluble fiber has been shown to decrease blood cholesterol levels, which can decrease the risk of atherosclerosis (fatty deposits) in the blood vessels. Your healthcare provider can refer you to a dietitian if you need extra help planning a heart-healthy diet.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/heart-healthy-diet\/\"><b>The best diet for heart health<\/b><\/a><\/p>\n<p><span style=\"font-weight: 400;\">You should also avoid alcohol while taking Eliquis. Although alcohol doesn\u2019t directly interact with Eliquis, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/eliquis-and-alcohol\/\"><span style=\"font-weight: 400;\">it may act as a blood thinner<\/span><\/a><span style=\"font-weight: 400;\">, potentially increasing the risk of bleeding, especially when consumed with Eliquis. It can also increase the risk of falls and injury.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Caffeine is also something to be mindful of when taking Eliquis, even though there is no direct interaction between Eliquis and caffeine. However, many patients taking Eliquis also have coronary artery disease and high blood pressure, so their healthcare providers may advise them to limit their caffeine intake. In addition, patients with AFib are often told to avoid caffeine altogether. Consult with your healthcare provider if you have concerns about caffeine and Eliquis.<\/span><\/p>\n<h2 id=\"eliquis-bleeding-risk\"><span style=\"font-weight: 400;\">Eliquis bleeding risk<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As with any of the blood thinners, Eliquis can increase the risk of bleeding. Signs of bleeding to watch out for include black, tarry stools, or bright red blood in the stool. Nose bleeds and bleeding from the gums may also occur while taking Eliquis. Be sure to alert your healthcare provider if you notice any of these signs.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our heart health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Heart Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">DOACs like Eliquis are generally <\/span><a href=\"https:\/\/thrombosis.org\/2020\/11\/doacs-vs-warfarin\/\"><span style=\"font-weight: 400;\">safer than other anticoagulants<\/span><\/a><span style=\"font-weight: 400;\">, such as warfarin, since they don\u2019t require INR monitoring and have fewer dietary restrictions. You can eat leafy greens while taking Eliquis, and you only need to limit certain citrus fruits. However, it\u2019s important to watch out for signs of gastrointestinal blood loss, which is a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/eliquis-side-effects\/\"><span style=\"font-weight: 400;\">serious side effect of Eliquis<\/span><\/a><span style=\"font-weight: 400;\"> and potentially life-threatening. Contact your healthcare provider immediately if you notice dark black or bloody stool.\u00a0<\/span><\/p>\n<h2 id=\"eliquis-faqs\"><span style=\"font-weight: 400;\">Eliquis FAQs<\/span><\/h2>\n<h3 id=\"can-i-eat-broccoli-while-taking-eliquis\"><span style=\"font-weight: 400;\">Can I eat broccoli while taking Eliquis?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Yes. You can eat broccoli and other leafy greens rich in vitamin K while taking Eliquis. In contrast, patients taking blood thinners such as warfarin need to be mindful of how much vitamin K is in their diet and ensure they avoid consuming too much one day and too little the next.\u00a0<\/span><\/p>\n<h3 id=\"is-eliquis-better-than-warfarin\"><span style=\"font-weight: 400;\">Is Eliquis better than warfarin?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In <\/span><a href=\"https:\/\/www.acc.org\/latest-in-cardiology\/clinical-trials\/2013\/07\/19\/12\/07\/aristotle\"><span style=\"font-weight: 400;\">clinical trials<\/span><\/a><span style=\"font-weight: 400;\">, Eliquis was found to be more effective than warfarin in lowering the risk of stroke, systemic embolism, and bleeding episodes. But warfarin is a common drug that\u2019s highly effective itself. In addition, insurance companies may not always cover Eliquis, as warfarin is much cheaper. The best drug for you can only be determined by your healthcare provider, who can consider your medical conditions, medical history, and other medications and supplements you\u2019re taking that could interact with Eliquis or warfarin.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/es\/recursos\/alimentos-a-evitar-con-eliquis\"><span style=\"font-weight: 400;\">Lea este art\u00edculo en espa\u00f1ol aqu\u00ed.<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eliquis (apixaban) is a blood thinner that belongs to a class of medications called direct oral anticoagulants (DOACs). It is used to prevent and treat blood clots in patients with deep vein thrombosis (DVT), pulmonary embolism (PE), and nonvalvular atrial fibrillation (AFib), which is a type of irregular heartbeat that\u2019s not caused by a heart [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":52597,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[737],"coauthors":[20033],"class_list":["post-52428","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-heart-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What foods to avoid while on Eliquis<\/title>\n<meta name=\"description\" content=\"Eliquis doesn\u2019t have as many food restrictions as other blood thinners, but there are certain foods, herbs, and supplements you should consume in moderation.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/foods-to-avoid-with-eliquis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"What foods to avoid while on Eliquis\" \/>\n<meta property=\"og:description\" content=\"Eliquis doesn\u2019t have as many food restrictions as other blood thinners, but there are certain foods, herbs, and supplements you should consume in moderation.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/foods-to-avoid-with-eliquis\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2022-07-06T19:20:08+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-01T23:59:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/06\/foods-to-avoid-while-on-Eliquis.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Jesse P. 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Houghton, MD, FACG\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/foods-to-avoid-with-eliquis\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/foods-to-avoid-with-eliquis\\\/\"},\"author\":{\"name\":\"Christie Falzone\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/5ff7c7bb5ce0c66a6962ecf7c8d7941e\"},\"headline\":\"What foods to avoid while on 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