{"id":52493,"date":"2022-07-05T09:59:39","date_gmt":"2022-07-05T13:59:39","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=52493"},"modified":"2026-03-03T15:01:06","modified_gmt":"2026-03-03T20:01:06","slug":"trintellix-without-insurance","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/trintellix-without-insurance\/","title":{"rendered":"How much is Trintellix without insurance?"},"content":{"rendered":"

Trintellix<\/span><\/a> (vortioxetine) is a brand-name <\/span>antidepressant<\/span><\/a> used to treat <\/span>major depressive disorder<\/span><\/a> (MDD). The Trintellix price without insurance is around $699 for a 30-day supply. Currently, there is no lower-priced generic version, but that may change this year (2026). If the Trintellix price is an issue, a healthcare professional can prescribe a different type of generic antidepressant that costs less. If that\u2019s not possible, uninsured patients can still reduce the Trintellix cost through other means.<\/span><\/p>\n\t\t

\n\t\t\t

Save up to 80% on Trintellix with SingleCare<\/p>\n\t\t\t

Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

\n\t\t\t\t
\n\t\t\t\t\tTrintellix 20 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t\t\t
\n\t\t\t
\n\t\t\t\"Kroger\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$491.07\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
\n\t\t\t
\n\t\t\t\"Harris\t\t\t<\/div>\n\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t$491.07\n\t\t\t\t<\/div>\n\t\t\t\t
\n\t\t\t\t\ti<\/span>\n\t\t\t\t\tPrice with signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t
\n\t\t\t\tGet free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\tSee Trintellix prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n

RELATED: <\/b>Antidepressants coupons and resources<\/b><\/a><\/p>\n

How much does Trintellix cost without insurance?<\/span><\/h2>\n

The cost of Trintellix without insurance is about $699 for a 30-day supply of 30, 20 mg tablets. That works out to $23 per pill. A year of treatment could cost over $8,000.<\/span><\/p>\n

Trintellix can be prescribed as a first-line treatment for depression, but healthcare professionals typically start with similar, more affordable antidepressants such as <\/span>SSRIs<\/span><\/a> and <\/span>SNRIs<\/span><\/a>. Like Trintellix, these drugs increase serotonin in the brain.<\/span><\/p>\n

If a Trintellix prescription is too expensive, ask the prescriber about SSRIs and SNRIs. They are widely available in affordable generic versions. If these have already been tried, ask about other types of antidepressants, including <\/span>tricyclic antidepressants<\/span><\/a>, <\/span>MAO inhibitors<\/span><\/a> (MAOIs), and <\/span>atypical antidepressants<\/span><\/a>.\u00a0<\/span><\/p>\n

Over-the-counter drugs, herbal remedies, and dietary supplements can help improve mood or the occasional blues, but they are not effective substitutes for prescription medications for people with major depressive disorder.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n
Compare Trintellix prices to similar atypical antidepressants<\/span><\/th>\n<\/tr>\n<\/thead>\n
Drug name<\/b><\/td>\nPrice without insurance for brand-name drug<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Trintellix<\/span><\/a> (vortioxetine)<\/span><\/td>\n$699 per 30, 20 mg tablets<\/span><\/td>\n$491 per 30, 20 mg tablets of brand-name Trintellix at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Viibryd (vilazodone)<\/span><\/td>\n$436 per 30, 40 mg tablets<\/span><\/td>\n$35 per 30, 40 mg tablets of generic Viibryd at CVS Pharmacy<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Wellbutrin SR\u00a0<\/span>(bupropion sustained-release)\u00a0<\/span><\/td>\n$565 for 60, 150 mg tablets<\/span><\/td>\n$6 for 60, 150 mg tablets of generic bupropion SR at Kroger\u00a0<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Remeron<\/span><\/p>\n

(<\/span>mirtazapine<\/span><\/a>)\u00a0<\/span><\/td>\n

$249 for 30, 15 mg tablets<\/span><\/td>\n$9 for 30, 15 mg tablets of generic Remeron at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Auvelity<\/span><\/a> (bupropion\/dextromethorphan)<\/span><\/td>\n$1,567 per 60, 45-105 mg tablets<\/span><\/td>\n$1,223 per 60, 45-105 mg tablets at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of 02\/02\/2026. Click the link under \u201cSee our lowest price\u201d to see the latest drug prices.<\/span><\/i><\/p>\n

Is Trintellix covered by insurance?<\/span><\/h2>\n

Many commercial health insurance plans, Medicare drug plans, Medicaid, and the VA cover Trintellix, but some insurance companies may require prior authorization. The Trintellix out-of-pocket cost with insurance will depend on the plan\u2019s formulary, deductible, copay costs, or coinsurance, if any.<\/span><\/p>\n

How to get Trintellix without insurance<\/span><\/h2>\n

Most antidepressants are affordable, but new brand-name treatments like Trintellix can be challenging to pay for month after month. Pharmaceutical companies may offer patient assistance programs, rebates, or manufacturer coupons, but eligibility requirements and other hurdles must be met. Fortunately, patient assistance programs and manufacturer offers don\u2019t exhaust all the options. Here are more ways to reduce the cost of Trintellix without insurance.<\/span><\/p>\n

1. Start by using a SingleCare savings card<\/span><\/h3>\n

With a free <\/span>Trintellix coupon<\/span><\/a> from SingleCare, people can save over $200 on a 30-day supply. With <\/span>SingleCare\u2019s bonus loyalty program<\/span><\/a>, people who regularly take advantage of SingleCare discounts can earn additional savings on future purchases and refills.<\/span><\/p>\n

2. Ask the prescriber about generic antidepressants<\/span><\/h3>\n

Healthcare professionals have a whole arsenal of <\/span>effective antidepressants<\/span><\/a> to battle depression. Most are available as inexpensive generics, affordable even without health insurance coverage. Unfortunately, many of these will have already been tried before doctors consider Trintellix. Ask the prescriber for medical advice about the pros and cons of switching to less expensive antidepressants.<\/span><\/p>\n

3. Find the lowest price for Trintellix<\/span><\/h3>\n

All pharmacy prices are not created equal. Finding the lowest Trintellix price could save a significant amount of money, especially when using a SingleCare coupon.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Trintellix (vortioxetine) is a brand-name antidepressant used to treat major depressive disorder (MDD). The Trintellix price without insurance is around $699 for a 30-day supply. Currently, there is no lower-priced generic version, but that may change this year (2026). If the Trintellix price is an issue, a healthcare professional can prescribe a different type of […]<\/p>\n","protected":false},"author":15,"featured_media":52495,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[451,450,4350],"coauthors":[8861],"class_list":["post-52493","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-depression","tag-mental-health","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"\nHow much is Trintellix without insurance?<\/title>\n<meta name=\"description\" content=\"Trintellix without insurance costs $23 per tablet, or $699 per month for 30, 20 mg tablets. 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