{"id":52560,"date":"2022-07-12T12:30:32","date_gmt":"2022-07-12T16:30:32","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=52560"},"modified":"2026-01-16T13:28:02","modified_gmt":"2026-01-16T18:28:02","slug":"risperidone-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/risperidone-alternatives\/","title":{"rendered":"Risperidone alternatives: What can I take instead of risperidone?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/risperidone\"><span style=\"font-weight: 400;\">Risperidone<\/span><\/a><span style=\"font-weight: 400;\"> is a generic prescription medication that\u2019s approved by the Food and Drug Administration (FDA) for the treatment of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/schizophrenia-treatment-and-medications\"><span style=\"font-weight: 400;\">schizophrenia<\/span><\/a><span style=\"font-weight: 400;\">, bipolar mania, and irritability associated with <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/teaching-children-with-autism-medication\/\"><span style=\"font-weight: 400;\">autism<\/span><\/a><span style=\"font-weight: 400;\">. Risperidone is sometimes used <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label,<\/span><\/a><span style=\"font-weight: 400;\"> meaning without an FDA indication, for Tourette syndrome, aggression in patients with dementia, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/ocd-treatment-and-medications\"><span style=\"font-weight: 400;\">obsessive-compulsive disorder<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">major depressive disorder<\/span><\/a><span style=\"font-weight: 400;\">, and other psychiatric conditions. The brand-name version of risperidone is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/risperdal\/what-is\"><span style=\"font-weight: 400;\">Risperdal<\/span><\/a><span style=\"font-weight: 400;\">. While risperidone and Risperdal are effective for improving psychotic symptoms, they may also cause bothersome <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/risperdal-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\">. Fortunately, other antipsychotic medications are available for patients seeking a risperidone alternative.\u00a0<\/span><\/p>\n<h2 id=\"what-can-i-take-in-place-of-risperidone\"><span style=\"font-weight: 400;\">What can I take in place of risperidone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Risperidone belongs to a class of medications called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/atypical-antipsychotics\"><span style=\"font-weight: 400;\">atypical antipsychotics<\/span><\/a><span style=\"font-weight: 400;\">, also known as second-generation antipsychotics. These antipsychotic drugs help regulate <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/mood-stabilizers\"><span style=\"font-weight: 400;\">mood<\/span><\/a><span style=\"font-weight: 400;\"> and behavior by balancing levels of dopamine and serotonin in the brain. Patients who don\u2019t tolerate risperidone may want to try a different antipsychotic under the guidance of a healthcare provider. When choosing an alternative, it\u2019s important to consider the indication, dosage, side effects, and formulation of the medication. The table below outlines common risperidone alternatives based on some of these considerations. <\/span><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th class=\"title\" role=\"columnheader\" scope=\"col\">\n<h2 id=\"compare-risperidone-alternatives\"><span class=\"title\">Compare risperidone alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage<\/b><\/td>\n<td><b>Coupons<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Risperidone<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia, bipolar disorder, and irritability associated with autism<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia and bipolar disorder: starting dose is 0.5-2 mg per day\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Irritability associated with autism: starting dose is 0.25-0.5 mg per day, depending on weight<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/risperidone\"><span style=\"font-weight: 400;\">Risperidone coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><b>Abilify (aripiprazole)<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia, bipolar disorder, major depressive disorder, irritability associated with autism, Tourette\u2019s disorder<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia and bipolar disorder: 10-15 mg once daily\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Major depressive disorder, irritability associated with autism, and Tourette\u2019s disorder: 2 mg once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/abilify\"><span style=\"font-weight: 400;\">Abilify coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><b>Haloperidol<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Psychotic disorders, Tourette\u2019s disorder, severe behavioral disorders, and hyperactivity in children<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Adults: 0.5-2 mg twice or three times daily<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Children: 0.05 mg per kilogram of body weight per day<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/haloperidol\"><span style=\"font-weight: 400;\">Haloperidol coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><b>Invega (paliperidone)<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia, schizoaffective disorder<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3-6 mg once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/invega\"><span style=\"font-weight: 400;\">Invega coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><b>Seroquel (quetiapine)<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia, bipolar disorder<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Starting dose is 25 mg twice daily and gradually increased<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/seroquel\"><span style=\"font-weight: 400;\">Seroquel coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><b>Zyprexa (olanzapine)<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia, bipolar disorder, treatment-resistant depression<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5-20 mg once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa\"><span style=\"font-weight: 400;\">Zyprexa coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Mental Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"top-5-risperidone-alternatives\"><span style=\"font-weight: 400;\">Top 5 risperidone alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most common alternatives to risperidone.<\/span><\/p>\n<h3 id=\"1-abilify-aripiprazole\"><span style=\"font-weight: 400;\">1. Abilify (aripiprazole)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Abilify is an atypical antipsychotic that is approved to treat the same conditions as risperidone: schizophrenia, bipolar disorder, and irritability associated with autism. In addition, Abilify is also used for Tourette\u2019s disorder and for major depressive disorder in combination with <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">antidepressants<\/span><\/a><span style=\"font-weight: 400;\">. As well as Abilify tablets, other dosage forms include a monthly injection (Abilify Maintena) and tablets containing a digital sensor (Abilify Mycite). For adults with schizophrenia or bipolar disorder, the recommended starting <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/abilify\/dosage\"><span style=\"font-weight: 400;\">dose<\/span><\/a><span style=\"font-weight: 400;\"> of Abilify is 10 mg or 15 mg once daily.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The adverse effects of risperidone and Abilify are similar. They can include constipation and movement disorders such as tardive dyskinesia, which is characterized by involuntary and repetitive movements. However, Abilify is associated with lower incidences of weight gain, high cholesterol, and high blood sugar compared to risperidone.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/abilify-side-effects\/\"><b>Abilify side effects and how to avoid them<\/b><\/a><\/p>\n<h3 id=\"2-haloperidol\"><span style=\"font-weight: 400;\">2. Haloperidol<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/haloperidol\/what-is\"><span style=\"font-weight: 400;\">Haloperidol<\/span><\/a><span style=\"font-weight: 400;\"> is another medication used to treat psychotic disorders such as schizophrenia, as well as severe behavioral problems and hyperactivity in children. It can also be used to control tics due to Tourette\u2019s disorder. Unlike risperidone, haloperidol is an older first-generation antipsychotic, but it works in the same way by targeting chemical receptors in the brain to balance dopamine levels. Haloperidol is a generic drug that is also available under the brand name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/haldol\/what-is\"><span style=\"font-weight: 400;\">Haldol<\/span><\/a><span style=\"font-weight: 400;\">. The dosage depends on the condition being treated, but haloperidol tablets are typically given at 0.5 mg to 2 mg twice or three times daily for adults with moderate psychosis symptoms.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Common side effects of haloperidol include sedation, weight gain, and EPS. Because of its ability to cause abnormal movements, haloperidol should not be used in individuals with Parkinson\u2019s disease. A serious side effect called neuroleptic malignant syndrome (NMS) can also occur. Patients who notice symptoms of NMS, including fever, sweating, muscle rigidity, and mental status changes, should immediately stop haloperidol and seek medical help right away.<\/span><\/p>\n<h3 id=\"3-zyprexa-olanzapine\"><span style=\"font-weight: 400;\">3. Zyprexa (olanzapine)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa\/what-is\"><span style=\"font-weight: 400;\">Zyprexa <\/span><\/a><span style=\"font-weight: 400;\">is a popular alternative to risperidone, indicated for the treatment of schizophrenia, bipolar disorder, and treatment-resistant depression (in combination with an antidepressant). Zyprexa and risperidone are both atypical antipsychotics and are available in a variety of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa\/dosage\"><span style=\"font-weight: 400;\">dosage<\/span><\/a><span style=\"font-weight: 400;\"> forms. In addition to regular tablets, Zyprexa comes as an orally disintegrating tablet (Zyprexa Zydis) that may be preferable for patients who have a hard time swallowing pills. An injectable form known as Zyprexa Relprevv is also available. The standard maintenance dosage of Zyprexa is 5 mg to 20 mg once daily.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Zyprexa and risperidone are both known to affect metabolism, leading to weight gain, high blood sugar, and high cholesterol. In a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16625629\/\"><span style=\"font-weight: 400;\">systematic review<\/span><\/a><span style=\"font-weight: 400;\"> comparing these two drugs, people taking risperidone were less likely to gain weight compared to those taking Zyprexa, but patients on risperidone had more sexual dysfunction. Both drugs were effective in alleviating symptoms of schizophrenia.<\/span><\/p>\n<h3 id=\"4-seroquel-quetiapine\"><span style=\"font-weight: 400;\">4. Seroquel (quetiapine)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/seroquel\/what-is\"><span style=\"font-weight: 400;\">Seroquel<\/span><\/a><span style=\"font-weight: 400;\"> also belongs to the class of atypical antipsychotics and is FDA approved to treat schizophrenia and bipolar disorder. The extended-release version (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/seroquel-xr\/what-is\"><span style=\"font-weight: 400;\">Seroquel XR<\/span><\/a><span style=\"font-weight: 400;\">) is also approved as an adjunctive treatment for major depressive disorder. The immediate-release version of Seroquel is usually started at a low dose of 25 mg twice daily for the treatment of schizophrenia. Seroquel XR is longer acting and can be given once daily.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The most common side effects of Seroquel are drowsiness, dizziness, low blood pressure upon standing, weight gain, high cholesterol, and high blood sugar. Compared to risperidone, Seroquel is <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20187598\/\"><span style=\"font-weight: 400;\">less likely<\/span><\/a><span style=\"font-weight: 400;\"> to cause EPS and is a better choice for people with movement disorders such as Parkinson\u2019s disease.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/seroquel-side-effects\/\"><b>Seroquel side effects, warnings, interactions, and how to avoid them<\/b><\/a><\/p>\n<h3 id=\"5-invega-paliperidone\"><span style=\"font-weight: 400;\">5. Invega (paliperidone)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/invega\/what-is\"><span style=\"font-weight: 400;\">Invega <\/span><\/a><span style=\"font-weight: 400;\">is an atypical antipsychotic indicated for the treatment of schizophrenia and schizoaffective disorder. The active ingredient in Invega, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paliperidone-er\"><span style=\"font-weight: 400;\">paliperidone<\/span><\/a><span style=\"font-weight: 400;\">, is a metabolite of risperidone and works similarly in the body. There are two injectable forms of Invega known as Invega Sustenna, given monthly, and Invega Trinza, given every three months. Invega tablets are dosed at 6 mg once daily for adults and 3 mg once daily for adolescents with schizophrenia.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because Invega and risperidone have a similar mechanism of action, they also have many overlapping side effects. Patients taking Invega should be monitored for changes in weight and cholesterol, and blood sugar levels. Another common side effect of Invega is increased levels of a hormone called prolactin, which can lead to irregular periods in women and sexual dysfunction in men.<\/span><\/p>\n<p><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/resources\/schizophrenia\"><b>Schizophrenia Medication Coupons &amp; Resources<\/b><\/a><\/p>\n<h2 id=\"natural-alternatives-to-risperidone\"><span style=\"font-weight: 400;\">Natural alternatives to risperidone<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are some natural alternatives to risperidone that can help alleviate the severity of psychotic disorders. However, these alternative remedies may not be enough to manage symptoms and do not replace prescription antipsychotics in people who need them. A healthcare provider or psychiatrist is the best resource to determine the treatment plan that improves your quality of life.\u00a0<\/span><\/p>\n<h3 id=\"healthy-diet\"><span style=\"font-weight: 400;\">Healthy diet<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31192814\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">studies<\/span><\/a><span style=\"font-weight: 400;\"> have found that a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/does-keto-diet-work\/\"><span style=\"font-weight: 400;\">ketogenic diet<\/span><\/a><span style=\"font-weight: 400;\"> can help people with schizophrenia. A ketogenic diet consists of foods that are low in carbohydrates and high in fat, such as fatty fish, eggs, nuts, avocados, and olive oil. It\u2019s thought that the ketogenic diet improves psychiatric symptoms by restoring energy metabolism in the brain, although more research is needed to fully understand its effect.<\/span><\/p>\n<h3 id=\"exercise\"><span style=\"font-weight: 400;\">Exercise\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Regular exercise has been shown to improve mental health in several ways. In patients with schizophrenia, exercise was <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30858639\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">found<\/span><\/a><span style=\"font-weight: 400;\"> to improve cognition, quality of life, and negative symptoms such as loss of motivation. Effective types of exercise can include yoga, brisk walking, biking, or swimming.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/depression-caused-by-physical-illness\/\"><b>The link between physical and mental health<\/b><\/a><\/p>\n<h3 id=\"supplements\"><span style=\"font-weight: 400;\">Supplements<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There is some evidence supporting the use of certain supplements for psychotic disorders. B vitamins, vitamin D, folic acid, and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/fatty-acids\"><span style=\"font-weight: 400;\">omega-3 fatty acids<\/span><\/a><span style=\"font-weight: 400;\"> may help symptoms of schizophrenia and bipolar disorder when used along with prescription medications. These nutrients can be found in foods or over-the-counter supplements.<\/span><\/p>\n<h2 id=\"how-to-switch-to-a-risperidone-alternative\"><span style=\"font-weight: 400;\">How to switch to a risperidone alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It\u2019s important to talk to a healthcare provider before making the switch to a risperidone alternative. Unless a serious side effect occurs, it\u2019s not safe to suddenly stop taking risperidone because doing so can lead to antipsychotic withdrawal. Symptoms of withdrawal can include agitation, anxiety, restlessness, insomnia, sweating, and involuntary movements. The dose of risperidone may be gradually tapered down to avoid these withdrawal effects.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A healthcare provider can also provide information about supplements and potential drug interactions that may occur when they are taken alongside an antipsychotic. Make sure to discuss all changes in prescription and over-the-counter medicines, vitamins, and supplements with your healthcare provider first. If a medication is not covered by your insurance, you can use a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare discount card<\/span><\/a><span style=\"font-weight: 400;\"> to pay as low as $9 for 30, 1 mg tablets of risperidone instead of the average cost of $127 without insurance.<\/span><\/p>\n<p><small><i><span style=\"font-weight: 400;\">The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of Jan. 16, 2026. Prices vary by pharmacy. Visit our <\/span><\/i><a href=\"https:\/\/www.singlecare.com\/prescription\/risperidone\"><i><span style=\"font-weight: 400;\">risperidone coupon page<\/span><\/i><\/a><i><span style=\"font-weight: 400;\"> for updated risperidone prices near you.<\/span><\/i><small><\/small><\/small><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Risperidone is a generic prescription medication that\u2019s approved by the Food and Drug Administration (FDA) for the treatment of schizophrenia, bipolar mania, and irritability associated with autism. Risperidone is sometimes used off-label, meaning without an FDA indication, for Tourette syndrome, aggression in patients with dementia, obsessive-compulsive disorder, major depressive disorder, and other psychiatric conditions. The [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":52587,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[450,4350],"coauthors":[20753],"class_list":["post-52560","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-mental-health","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top risperidone alternatives and how to switch your Rx<\/title>\n<meta name=\"description\" content=\"Abilify, Haloperidol, Zyprexa, Seroquel, and Invega are some risperidone alternatives. 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