{"id":53078,"date":"2022-08-10T15:43:34","date_gmt":"2022-08-10T19:43:34","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53078"},"modified":"2026-01-05T14:39:20","modified_gmt":"2026-01-05T19:39:20","slug":"fluoxetine-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/","title":{"rendered":"Fluoxetine alternatives for depression and anxiety"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Most people know fluoxetine as the antidepressant medication Prozac, but that brand is no longer sold in the U.S. Fluoxetine is its generic name and remains available in the U.S. The <\/span><span style=\"font-weight: 400;\">Food and Drug Administration<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">) has approved its use for several <\/span><span style=\"font-weight: 400;\">mental health<\/span><span style=\"font-weight: 400;\"> conditions. These include <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/depression-treatment-and-medications\"><span style=\"font-weight: 400;\">major depressive disorder<\/span><\/a><span style=\"font-weight: 400;\">, bipolar depression, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/anxiety-treatment-and-medications\"><span style=\"font-weight: 400;\">anxiety<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/anxiety-attack-vs-panic-attack\/\"><span style=\"font-weight: 400;\">panic disorder<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">bulimia<\/span><span style=\"font-weight: 400;\">, premenstrual dysphoric disorder (PMDD), and <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/ocd-treatment-and-medications\"><span style=\"font-weight: 400;\">obsessive compulsive disorder<\/span><\/a><span style=\"font-weight: 400;\"> (OCD). Though it\u2019s one of the most commonly prescribed antidepressants, fluoxetine may not work for some people because of ineffectiveness or side effects. The availability of alternatives will vary depending on the condition being treated. For some of the more specialized indications, doctors may need to use an off-label treatment.\u00a0<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl\/what-is\"><b>What is fluoxetine?<\/b><\/a><b> | <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl\"><b>Fluoxetine coupons<\/b><\/a><\/p>\n<h2 id=\"what-can-i-take-instead-of-fluoxetine\"><span style=\"font-weight: 400;\">What can I take instead of <\/span><span style=\"font-weight: 400;\">fluoxetine<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Though commonly prescribed as a first-line treatment, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl\"><span style=\"font-weight: 400;\">fluoxetine<\/span><\/a><span style=\"font-weight: 400;\"> isn\u2019t always the right treatment choice. It may not completely resolve the condition, or people may experience <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/fluoxetine-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> they can\u2019t live with. Additionally, fluoxetine has <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/fluoxetine-interactions\/\"><span style=\"font-weight: 400;\">several worrisome <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><\/a><span style=\"font-weight: 400;\">, so it may need to be changed if other drugs prescribed for different health conditions are more critical.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Luckily, there are several different alternatives available <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/medication-for-anxiety-and-depression\/\"><span style=\"font-weight: 400;\">to treat depression or anxiety<\/span><\/a><span style=\"font-weight: 400;\">. A doctor\u2019s first choice may be to try a different <\/span><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitor<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">SSRI<\/span><span style=\"font-weight: 400;\">) like fluoxetine for depression. Healthcare professionals could also choose a drug from a completely <\/span><span style=\"font-weight: 400;\">different antidepressant<\/span><span style=\"font-weight: 400;\"> class, such as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/snris\"><span style=\"font-weight: 400;\">serotonin-<\/span><span style=\"font-weight: 400;\">norepinephrine reuptake inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">SNRIs<\/span><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/atypical-antidepressants\"><span style=\"font-weight: 400;\">atypical <\/span><span style=\"font-weight: 400;\">antidepressants<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wellbutrin-xl\"><span style=\"font-weight: 400;\">Wellbutrin<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl\"><span style=\"font-weight: 400;\">bupropion<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tricyclic-antidepressants\/\"><span style=\"font-weight: 400;\">tricyclic antidepressants<\/span><\/a><span style=\"font-weight: 400;\"> (TCAs), or <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/maois\"><span style=\"font-weight: 400;\">monoamine oxidase inhibitors<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">MAOIs<\/span><span style=\"font-weight: 400;\">). For anxiety conditions, healthcare providers can prescribe a different SSRI or choose an SNRI, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl\"><span style=\"font-weight: 400;\">buspirone<\/span><\/a><span style=\"font-weight: 400;\">, or a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/benzodiazepines\"><span style=\"font-weight: 400;\">benzodiazepine<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other conditions have fewer medication options for clinicians to choose from to help relieve symptoms. Other drugs approved for OCD treatment are other antidepressants: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paxil\"><span style=\"font-weight: 400;\">Paxil<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paroxetine-hcl\"><span style=\"font-weight: 400;\">paroxetine<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/sertraline-hcl\"><span style=\"font-weight: 400;\">sertraline<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/fluvoxamine-maleate\"><span style=\"font-weight: 400;\">fluvoxamine<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clomipramine-hcl\"><span style=\"font-weight: 400;\">clomipramine<\/span><\/a><span style=\"font-weight: 400;\">. However, doctors often use other drugs off-label for OCD when antidepressants are ineffective. Even fewer options are available to treat PMDD, as only fluoxetine and sertraline are FDA-approved. Fluoxetine is the only drug approved to treat bulimia.<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/best-antidepressant\/\"><b>What\u2019s the best <\/b><b>antidepressant<\/b><b> for me?<\/b><\/a><b>\u00a0<\/b><\/p>\n<table class=\" singlecare-table\" role=\"table\">\n<thead>\n<tr>\n<th colspan=\"4\">\n<h3 id=\"compare-fluoxetine-alternatives\"><span style=\"font-weight: 400;\">Compare <\/span><span style=\"font-weight: 400;\">fluoxetine<\/span><span style=\"font-weight: 400;\"> alternatives<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Price without insurance<\/b><\/td>\n<td><b>SingleCare price<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl\/what-is\"><span style=\"font-weight: 400;\">Fluoxetine<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$68 for 30, 20 mg capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$6 for 30, 20 mg capsules of generic fluoxetine at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\/what-is\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/sertraline-hcl\/what-is\"><span style=\"font-weight: 400;\">sertraline<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$544 for 30, 50 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9 for 30, 50 mg tablets of generic sertraline at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/celexa\/what-is\"><span style=\"font-weight: 400;\">Celexa<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/citalopram-hydrobromide\/what-is\"><span style=\"font-weight: 400;\">citalopram<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$407 for 30, 20 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$6 for 30, 20 mg tablets of generic citalopram at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/celexa\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/paxil\/what-is\"><span style=\"font-weight: 400;\">Paxil<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paroxetine-hcl\/what-is\"><span style=\"font-weight: 400;\">paroxetine<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$756 for 30, 20 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$4 for 30, 20 mg tablets of generic paroxetine at Walmart<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/paxil\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/duloxetine-hcl\/what-is\"><span style=\"font-weight: 400;\">Duloxetine<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$229 for 30, 60 mg capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$8 for 30, 60 mg capsules of generic duloxetine at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/duloxetine-hcl\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/wellbutrin-xl\/what-is\"><span style=\"font-weight: 400;\">Wellbutrin XL<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl-er-sr\/what-is\"><span style=\"font-weight: 400;\">(bupropion <\/span><\/a><a href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl-er-xl\/what-is\"><span style=\"font-weight: 400;\">extended-release<\/span><\/a><a href=\"https:\/\/www.singlecare.com\/prescription\/bupropion-hcl-er-sr\/what-is\"><span style=\"font-weight: 400;\">)<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$3,636 for 30, 300 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$7 for 30, 150 mg tablets of generic bupropion ER at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/wellbutrin-xl\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/lexapro\/what-is\"><span style=\"font-weight: 400;\">Lexapro<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/escitalopram-oxalate\/what-is\"><span style=\"font-weight: 400;\">escitalopram<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$564 for 30, 10 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9 for 30, 10 mg tablets of generic escitalopram at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lexapro\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/symbyax\/what-is\"><span style=\"font-weight: 400;\">Symbyax<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/olanzapine-fluoxetine-hcl\"><span style=\"font-weight: 400;\">fluoxetine\/olanzapine<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$367 per 30, 3 mg\/25 mg capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$75 per 30, 3 mg\/25 mg capsules of generic Symbyax at CVS Pharmacy<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/symbyax\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/effexor-xr\/what-is\"><span style=\"font-weight: 400;\">Effexor XR <\/span><\/a><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/venlafaxine-hcl-er\/what-is\"><span style=\"font-weight: 400;\">venlafaxine extended-release<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$779 for 30, 150 mg capsules<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$6 for 30, 150 mg capsules of generic venlafaxine ER at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/effexor-xr\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/pristiq\/what-is\"><span style=\"font-weight: 400;\">Pristiq<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/desvenlafaxine-succinate-er\/what-is\"><span style=\"font-weight: 400;\">desvenlafaxine ER<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$543 for 30, 100 mg extended-release tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$18 for 30, 100 mg tablets of generic desvenlafaxine ER at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/pristiq\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/remeron\/what-is\"><span style=\"font-weight: 400;\">Remeron<\/span><\/a><\/p>\n<p><span style=\"font-weight: 400;\">(<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mirtazapine\/what-is\"><span style=\"font-weight: 400;\">mirtazapine<\/span><\/a><span style=\"font-weight: 400;\">)\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$246 for 30, 15 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$9 for 30, 15 mg tablets of generic mirtazapine at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/remeron\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl\/what-is\"><span style=\"font-weight: 400;\">Trazodone<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$38 for 30, 50 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$6 for 30, 50 mg tablets of generic trazodone at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/trazodone-hcl\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/trintellix\/what-is\"><span style=\"font-weight: 400;\">Trintellix<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">(vortioxetine)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$677 for 30, 20 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$466 for 30, 20 mg tablets of brand-name Trintellix at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/trintellix\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl\/what-is\"><span style=\"font-weight: 400;\">Buspirone<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$46 for 60, 5 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$5 for 60, 5 mg tablets of generic buspirone at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/buspirone-hcl\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"https:\/\/www.singlecare.com\/prescription\/fluvoxamine-maleate\/what-is\"><span style=\"font-weight: 400;\">Fluvoxamine<\/span><\/a><\/td>\n<td><span style=\"font-weight: 400;\">$96 for 30, 100 mg tablets<\/span><\/td>\n<td><span style=\"font-weight: 400;\">$16 for 30, 100 mg tablets of generic fluvoxamine at Kroger<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/fluvoxamine-maleate\"><span style=\"font-weight: 400;\">See latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><small>Prescription drug prices often change. These are the most accurate medication prices at the time of publishing in ZIP code 23666 as of 1\/06\/2025. The listed price without insurance references the price of brand-name drugs (unless otherwise specified). The listed SingleCare price references the price of generic drugs if available. Click the link under \u201cSavings options\u201d to see the latest drug prices.<\/small><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Fluoxetine with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tFluoxetine 20 mg (30 Capsule)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-kroger.svg\" alt=\"Kroger Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$6.36<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-harristeeter.svg\" alt=\"Harris Teeter Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$6.36<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/fluoxetine-hcl#blog-cta\" class=\"coupon-see-all-btn\">See Fluoxetine prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/side-effects-of-antidepressants\/\"><b>Going on antidepressants: A beginner\u2019s guide to side effects<\/b><\/a><\/p>\n<h2 id=\"top-5-fluoxetine-alternatives\"><span style=\"font-weight: 400;\">Top 5 <\/span><span style=\"font-weight: 400;\">fluoxetine<\/span><span style=\"font-weight: 400;\"> alternatives<\/span><\/h2>\n<h3 id=\"1-zoloft-sertraline\"><span style=\"font-weight: 400;\">1. <\/span><span style=\"font-weight: 400;\">Zoloft<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">sertraline<\/span><span style=\"font-weight: 400;\">)<\/span><\/h3>\n<p><a href=\"https:\/\/www.drugs.com\/zoloft.html\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><span style=\"font-weight: 400;\"> is an <\/span><span style=\"font-weight: 400;\">antidepressant<\/span><span style=\"font-weight: 400;\"> in the <\/span><span style=\"font-weight: 400;\">SSRI<\/span><span style=\"font-weight: 400;\"> class like fluoxetine. <\/span><span style=\"font-weight: 400;\">Zoloft<\/span><span style=\"font-weight: 400;\"> is the brand version, and <\/span><span style=\"font-weight: 400;\">sertraline<\/span><span style=\"font-weight: 400;\"> is the generic option. <\/span><span style=\"font-weight: 400;\">Major depressive disorder<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">obsessive-compulsive disorder<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">panic disorder<\/span><span style=\"font-weight: 400;\">, social <\/span><span style=\"font-weight: 400;\">anxiety disorder<\/span><span style=\"font-weight: 400;\">, premenstrual dysphoric disorder, and post-traumatic stress disorder are all managed with this medication. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\/dosage\"><span style=\"font-weight: 400;\">50 to 200 mg<\/span><\/a><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Zoloft<\/span><span style=\"font-weight: 400;\"> can be taken daily to manage these conditions. There are many <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\"> associated with the use of <\/span><span style=\"font-weight: 400;\">Zoloft,<\/span><span style=\"font-weight: 400;\"> and this should be reviewed with your healthcare specialist. The most common side effects include nausea, diarrhea, dry mouth, drowsiness, tremors, weight gain, and sexual problems. The most serious problem associated with Zoloft and other antidepressants is the risk of suicidal thoughts or behaviors in younger patients. Caretakers must monitor these patients carefully, particularly at the beginning of therapy.<\/span><\/p>\n<h3 id=\"2-celexa-citalopram\"><span style=\"font-weight: 400;\">2. <\/span><span style=\"font-weight: 400;\">Celexa<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">citalopram<\/span><span style=\"font-weight: 400;\">)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <\/span><span style=\"font-weight: 400;\">antidepressant<\/span> <a href=\"https:\/\/www.drugs.com\/celexa.html\"><span style=\"font-weight: 400;\">Celexa<\/span><\/a><span style=\"font-weight: 400;\"> is another brand of <\/span><span style=\"font-weight: 400;\">selective serotonin reuptake inhibitor<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">SSRI<\/span><span style=\"font-weight: 400;\">) used for the management of <\/span><span style=\"font-weight: 400;\">major depressive disorder<\/span><span style=\"font-weight: 400;\">. Citalopram is its generic version. <\/span><span style=\"font-weight: 400;\">Celexa<\/span><span style=\"font-weight: 400;\"> is associated with heart complications, so if there are any symptoms of chest pain, tell the prescriber immediately. Some Celexa drug reactions are very serious, so make sure the prescriber has a thorough list of all current and past medications. Most people on Celexa are prescribed <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/celexa\/dosage\"><span style=\"font-weight: 400;\">20 to 40 mg<\/span><\/a><span style=\"font-weight: 400;\"> once daily. Some <\/span><span style=\"font-weight: 400;\">common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/celexa-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> include nausea, diarrhea, fatigue, flu syndrome, anorexia, anxiety, vomiting, impotence, agitation, abdominal pain, dizziness, yawning, and sexual dysfunction.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/celexa-vs-prozac\/\"><b>Celexa<\/b><b> vs. <\/b><b>Prozac<\/b><b>: Differences, similarities, and which is better<\/b><\/a><b>\u00a0<\/b><\/p>\n<h3 id=\"3-paxil-paroxetine\"><span style=\"font-weight: 400;\">3. <\/span><span style=\"font-weight: 400;\">Paxil<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">paroxetine<\/span><span style=\"font-weight: 400;\">)<\/span><\/h3>\n<p><a href=\"https:\/\/www.drugs.com\/paxil.html\"><span style=\"font-weight: 400;\">Paxil<\/span><\/a><span style=\"font-weight: 400;\"> is an <\/span><span style=\"font-weight: 400;\">SSRI<\/span><span style=\"font-weight: 400;\"> like fluoxetine used for <\/span><span style=\"font-weight: 400;\">major depressive disorder<\/span><span style=\"font-weight: 400;\">, generalized anxiety disorder, panic disorder, social anxiety disorder, <\/span><span style=\"font-weight: 400;\">obsessive-compulsive disorder<\/span><span style=\"font-weight: 400;\">, and post-traumatic stress disorder. Paroxetine is the generic option available. As with other <\/span><span style=\"font-weight: 400;\">antidepressants<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">suicidal thoughts<\/span><span style=\"font-weight: 400;\"> will need to be closely monitored in younger patients. Anti-inflammatory medications such as aspirin, ibuprofen, or naproxen should be avoided because of the increased bleeding risk. <\/span><span style=\"font-weight: 400;\">Paxil<\/span><span style=\"font-weight: 400;\"> is taken once daily in the morning, usually a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paxil\/dosage\"><span style=\"font-weight: 400;\">20 to 50 mg<\/span><\/a><span style=\"font-weight: 400;\"> dose. <\/span><span style=\"font-weight: 400;\">Common <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/paxil-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> include sexual problems (impotence, anorgasmia), gastrointestinal disturbances (constipation, diarrhea), and neurological symptoms (dizziness, tremor, tingling).\u00a0<\/span><\/p>\n<h3 id=\"4-duloxetine\"><span style=\"font-weight: 400;\">4. <\/span><span style=\"font-weight: 400;\">Duloxetine<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Formerly known as brand-name Cymbalta, duloxetine is a selective serotonin and <\/span><span style=\"font-weight: 400;\">norepinephrine reuptake inhibitor<\/span><span style=\"font-weight: 400;\"> (SNRI). It is FDA-approved as a treatment of depression, generalized <\/span><span style=\"font-weight: 400;\">anxiety disorder<\/span><span style=\"font-weight: 400;\">, and some nerve or musculoskeletal pain conditions. For depression or anxiety, the standard dosage is <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/cymbalta\/dosage\"><span style=\"font-weight: 400;\">60 mg daily<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cymbalta-side-effects\/\"><span style=\"font-weight: 400;\">Common adverse reactions<\/span><\/a><span style=\"font-weight: 400;\"> include nausea, headache, <\/span><span style=\"font-weight: 400;\">weight loss<\/span><span style=\"font-weight: 400;\">, abdominal pain, fatigue, constipation, appetite loss, insomnia, and sexual dysfunction.<\/span><\/p>\n<h3 id=\"5-wellbutrin-xl-bupropion-er\"><span style=\"font-weight: 400;\">5. <\/span><span style=\"font-weight: 400;\">Wellbutrin<\/span><span style=\"font-weight: 400;\"> XL (bupropion ER)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">One of the most common reasons people stop taking antidepressants\u2014particularly SSRIs\u2014is <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/news\/sex-on-ssris\/\"><span style=\"font-weight: 400;\">sexual <\/span><span style=\"font-weight: 400;\">dysfunction<\/span><\/a><span style=\"font-weight: 400;\">: loss of libido, erectile dysfunction, orgasm issues, or other problems. Though not as powerful as SSRIs at treating depression, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wellbutrin-xl\/what-is\"><span style=\"font-weight: 400;\">Wellbutrin<\/span><span style=\"font-weight: 400;\"> XL<\/span><\/a><span style=\"font-weight: 400;\"> is a first-line antidepressant alternative that does not affect sexual function as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/wellbutrin-vs-prozac\/\"><span style=\"font-weight: 400;\">dramatically as other antidepressants<\/span><\/a><span style=\"font-weight: 400;\">. That\u2019s because it doesn\u2019t affect serotonin levels. The active ingredient, bupropion, is a <\/span><span style=\"font-weight: 400;\">norepinephrine<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">dopamine<\/span> <span style=\"font-weight: 400;\">reuptake<\/span><span style=\"font-weight: 400;\"> inhibitor (NDRI). These are neurotransmitters that increase brain activity. Dopamine in particular is a key part of the brain\u2019s pleasure and reward pathway. Common side effects include dry mouth, nausea, sore throat, trouble sleeping, dizziness, anxiety, and agitation.<\/span><\/p>\n<h2 id=\"over-the-counter-depression-or-anxiety-medications\"><span style=\"font-weight: 400;\">Over-the-counter depression or anxiety medications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are many over-the-counter medications and supplements marketed as safe ways to improve mood or calm worry and anxiety. At least one of those over-the-counter remedies successfully improves the symptoms of depression: <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/st-johns-wort\"><span style=\"font-weight: 400;\">St. John\u2019s wort<\/span><\/a><span style=\"font-weight: 400;\">. In a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7032678\/\"><span style=\"font-weight: 400;\">systematic review<\/span><\/a><span style=\"font-weight: 400;\"> of its use in patients with major depressive disorder, St. John\u2019s wort was almost equally effective as prescription antidepressants. The <\/span><a href=\"https:\/\/www.apa.org\/depression-guideline\/guideline.pdf\"><span style=\"font-weight: 400;\">American Psychiatric Association<\/span><\/a><span style=\"font-weight: 400;\"> recommends it as a stand-alone alternative treatment for mild to moderate major depressive disorder. However, St. John\u2019s wort has health-threatening drug interactions, so <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/st-johns-wort\/\"><span style=\"font-weight: 400;\">get medical advice<\/span><\/a><span style=\"font-weight: 400;\"> from a healthcare professional before starting the supplement.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other OTC products that may help improve a depressed mood include <\/span><a href=\"https:\/\/psychiatryonline.org\/pb\/assets\/raw\/sitewide\/practice_guidelines\/guidelines\/mdd-1410197717630.pdf\"><span style=\"font-weight: 400;\">S-adenosyl-L-methionine<\/span><\/a><span style=\"font-weight: 400;\"> (SAMe), <\/span><a href=\"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.ajp.2012.12010009\"><span style=\"font-weight: 400;\">creatinine<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/journals.lww.com\/bsam\/abstract\/2018\/02000\/acetyl_l_carnitine_supplementation_and_the.4.aspx\"><span style=\"font-weight: 400;\">carnitine<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0165032719317604\"><span style=\"font-weight: 400;\">glycyrrhizic acid<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/karger.com\/pps\/article\/88\/5\/263\/283146\/International-Society-for-Nutritional-Psychiatry\"><span style=\"font-weight: 400;\">omega-3 fatty acids<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28988944\/\"><span style=\"font-weight: 400;\">zinc<\/span><\/a><b>. <\/b><span style=\"font-weight: 400;\">None of these supplements are proven effective in ameliorating clinical depression or anxiety.\u00a0<\/span><\/p>\n<h2 id=\"natural-alternatives-to-fluoxetine\"><span style=\"font-weight: 400;\">Natural alternatives to <\/span><span style=\"font-weight: 400;\">fluoxetine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The only proven and APA-recommended natural treatment for depression and anxiety is cognitive behavioral therapy (CBT). It is so effective that the APA recommends it as a first-line treatment along with medications. However, CBT and other types of psychotherapy take time and commitment to show results.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other non-pharmaceutical ways to improve mood include <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/depression-caused-by-physical-illness\/\"><span style=\"font-weight: 400;\">exercise<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/depression-diet\/\"><span style=\"font-weight: 400;\">diets<\/span><\/a><span style=\"font-weight: 400;\"> that include omega-3 fats and tryptophan, and light therapy. Always get medical advice from a healthcare professional before trying alternative treatments.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/depression-diet\/\"><b>The best diet to fight depression<\/b><\/a><\/p>\n<h2 id=\"how-to-switch-to-a-fluoxetine-alternative\"><span style=\"font-weight: 400;\">How to switch to a <\/span><span style=\"font-weight: 400;\">fluoxetine<\/span><span style=\"font-weight: 400;\"> alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because of the many negative <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> associated with <\/span><span style=\"font-weight: 400;\">fluoxetine<\/span><span style=\"font-weight: 400;\">, some people may need to stop the medication altogether. Unfortunately, <\/span><span style=\"font-weight: 400;\">antidepressants<\/span><span style=\"font-weight: 400;\"> cannot be stopped abruptly. Before discontinuation, the healthcare provider needs to slowly wean you off the medication to prevent <\/span><a href=\"https:\/\/www.health.harvard.edu\/diseases-and-conditions\/going-off-antidepressants\"><span style=\"font-weight: 400;\">antidepressant<\/span><span style=\"font-weight: 400;\"> withdrawal<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When switching to a different prescription drug, consider possible side effects and drug interactions. Cost is another consideration. All these can be discussed with the prescriber.<\/span><\/p>\n<h2 id=\"choosing-the-right-path-for-depression-treatment\"><span style=\"font-weight: 400;\">Choosing the right path for depression treatment<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The right path for depression starts with talking to a healthcare professional. Their experience is invaluable. Treatment usually starts with a first-line antidepressant medication like fluoxetine or Wellbutrin, but medication alone is not the most effective treatment method. Medication in conjunction with psychotherapy is a necessary part of recovery. Both the medication and the psychotherapy will take time to show results. The medication will relieve symptoms. Psychotherapy will teach skills to handle reactions, habits, and mood; a more permanent solution to a mood disorder. Once the proper coping tools are learned to manage depression, medication regimens can be reduced or discontinued entirely.<\/span><\/p>\n<p><i><span style=\"font-weight: 400;\">The SingleCare prices in this article are the most accurate at the time of publishing in ZIP code 23666 as of 1\/6\/2025. Prices vary by pharmacy. Visit our fluoxetine coupon page for updated fluoxetine prices near you.<\/span><\/i><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Most people know fluoxetine as the antidepressant medication Prozac, but that brand is no longer sold in the U.S. Fluoxetine is its generic name and remains available in the U.S. The Food and Drug Administration (FDA) has approved its use for several mental health conditions. These include major depressive disorder, bipolar depression, anxiety, panic disorder, [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":53084,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9777,451,450],"coauthors":[20627],"class_list":["post-53078","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-anxiety","tag-depression","tag-mental-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.8 (Yoast SEO v27.8) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Explore effective alternatives to fluoxetine for depression and anxiety<\/title>\n<meta name=\"description\" content=\"Celexa, duloxetine, Lexapro, Paxil, and Zoloft are some fluoxetine alternatives. Get the full list here, including SSRI cost-saving options.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Fluoxetine alternatives for depression and anxiety\" \/>\n<meta property=\"og:description\" content=\"Celexa, duloxetine, Lexapro, Paxil, and Zoloft are some fluoxetine alternatives. Get the full list here, including SSRI cost-saving options.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2022-08-10T19:43:34+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-05T19:39:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/08\/fluoxetine-alternatives.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Marquissa Beverly, DPM\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Marquissa Beverly, DPM\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/\"},\"author\":{\"name\":\"Christie Falzone\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/5ff7c7bb5ce0c66a6962ecf7c8d7941e\"},\"headline\":\"Fluoxetine alternatives for depression and anxiety\",\"datePublished\":\"2022-08-10T19:43:34+00:00\",\"dateModified\":\"2026-01-05T19:39:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/\"},\"wordCount\":1664,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/08\\\/fluoxetine-alternatives.png\",\"keywords\":[\"Anxiety\",\"Depression\",\"Mental health\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/\",\"name\":\"Explore effective alternatives to fluoxetine for depression and anxiety\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/08\\\/fluoxetine-alternatives.png\",\"datePublished\":\"2022-08-10T19:43:34+00:00\",\"dateModified\":\"2026-01-05T19:39:20+00:00\",\"description\":\"Celexa, duloxetine, Lexapro, Paxil, and Zoloft are some fluoxetine alternatives. Get the full list here, including SSRI cost-saving options.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/08\\\/fluoxetine-alternatives.png\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/08\\\/fluoxetine-alternatives.png\",\"width\":1920,\"height\":1080,\"caption\":\"Hand holding Rx pills: What can I take instead of fluoxetine?\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/fluoxetine-alternatives\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Fluoxetine alternatives for depression and anxiety\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"name\":\"The Checkup, a health blog by SingleCare\",\"description\":\"Read the latest in prescription, wellness, and healthcare news\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\",\"name\":\"SingleCare\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"contentUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2020\\\/01\\\/placeholderimage-1.jpg\",\"width\":1200,\"height\":630,\"caption\":\"SingleCare\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/www.facebook.com\\\/singlecare\",\"https:\\\/\\\/x.com\\\/SingleCare\",\"https:\\\/\\\/www.instagram.com\\\/singlecare\\\/?hl=en\",\"https:\\\/\\\/www.linkedin.com\\\/company\\\/singlecare\\\/\",\"https:\\\/\\\/www.youtube.com\\\/channel\\\/UCd9kiPIjCQw95-2BHCYePKA\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/5ff7c7bb5ce0c66a6962ecf7c8d7941e\",\"name\":\"Christie Falzone\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=gf47683752158743086d9c95bc1ebdaa7\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g\",\"caption\":\"Christie Falzone\"},\"description\":\"Christie Falzone recently graduated summa cum laude from Old Dominion University in Norfolk, Virginia, with a bachelor\u2019s degree in professional writing. During her time in college, she developed a passion for helping children and volunteers as a Court Appointed Special Advocate on behalf of foster youth.\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/author\\\/cfalzone\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Explore effective alternatives to fluoxetine for depression and anxiety","description":"Celexa, duloxetine, Lexapro, Paxil, and Zoloft are some fluoxetine alternatives. Get the full list here, including SSRI cost-saving options.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/","og_locale":"en_US","og_type":"article","og_title":"Fluoxetine alternatives for depression and anxiety","og_description":"Celexa, duloxetine, Lexapro, Paxil, and Zoloft are some fluoxetine alternatives. Get the full list here, including SSRI cost-saving options.","og_url":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/","og_site_name":"The Checkup","article_publisher":"https:\/\/www.facebook.com\/singlecare","article_published_time":"2022-08-10T19:43:34+00:00","article_modified_time":"2026-01-05T19:39:20+00:00","og_image":[{"width":1920,"height":1080,"url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/08\/fluoxetine-alternatives.png","type":"image\/png"}],"author":"Marquissa Beverly, DPM","twitter_card":"summary_large_image","twitter_creator":"@SingleCare","twitter_site":"@SingleCare","twitter_misc":{"Written by":"Marquissa Beverly, DPM","Est. reading time":"8 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#article","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/"},"author":{"name":"Christie Falzone","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/5ff7c7bb5ce0c66a6962ecf7c8d7941e"},"headline":"Fluoxetine alternatives for depression and anxiety","datePublished":"2022-08-10T19:43:34+00:00","dateModified":"2026-01-05T19:39:20+00:00","mainEntityOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/"},"wordCount":1664,"publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/08\/fluoxetine-alternatives.png","keywords":["Anxiety","Depression","Mental health"],"articleSection":["Drug Info"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/","url":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/","name":"Explore effective alternatives to fluoxetine for depression and anxiety","isPartOf":{"@id":"https:\/\/www.singlecare.com\/blog\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#primaryimage"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#primaryimage"},"thumbnailUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/08\/fluoxetine-alternatives.png","datePublished":"2022-08-10T19:43:34+00:00","dateModified":"2026-01-05T19:39:20+00:00","description":"Celexa, duloxetine, Lexapro, Paxil, and Zoloft are some fluoxetine alternatives. Get the full list here, including SSRI cost-saving options.","breadcrumb":{"@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#primaryimage","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/08\/fluoxetine-alternatives.png","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/08\/fluoxetine-alternatives.png","width":1920,"height":1080,"caption":"Hand holding Rx pills: What can I take instead of fluoxetine?"},{"@type":"BreadcrumbList","@id":"https:\/\/www.singlecare.com\/blog\/fluoxetine-alternatives\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.singlecare.com\/blog\/"},{"@type":"ListItem","position":2,"name":"Fluoxetine alternatives for depression and anxiety"}]},{"@type":"WebSite","@id":"https:\/\/www.singlecare.com\/blog\/#website","url":"https:\/\/www.singlecare.com\/blog\/","name":"The Checkup, a health blog by SingleCare","description":"Read the latest in prescription, wellness, and healthcare news","publisher":{"@id":"https:\/\/www.singlecare.com\/blog\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.singlecare.com\/blog\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.singlecare.com\/blog\/#organization","name":"SingleCare","url":"https:\/\/www.singlecare.com\/blog\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/","url":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","contentUrl":"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2020\/01\/placeholderimage-1.jpg","width":1200,"height":630,"caption":"SingleCare"},"image":{"@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/singlecare","https:\/\/x.com\/SingleCare","https:\/\/www.instagram.com\/singlecare\/?hl=en","https:\/\/www.linkedin.com\/company\/singlecare\/","https:\/\/www.youtube.com\/channel\/UCd9kiPIjCQw95-2BHCYePKA"]},{"@type":"Person","@id":"https:\/\/www.singlecare.com\/blog\/#\/schema\/person\/5ff7c7bb5ce0c66a6962ecf7c8d7941e","name":"Christie Falzone","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=gf47683752158743086d9c95bc1ebdaa7","url":"https:\/\/secure.gravatar.com\/avatar\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/2e99585820d49affcf442acba86e464b68d836bf071db26829d667da12209555?s=96&d=mm&r=g","caption":"Christie Falzone"},"description":"Christie Falzone recently graduated summa cum laude from Old Dominion University in Norfolk, Virginia, with a bachelor\u2019s degree in professional writing. During her time in college, she developed a passion for helping children and volunteers as a Court Appointed Special Advocate on behalf of foster youth.","url":"https:\/\/www.singlecare.com\/blog\/author\/cfalzone\/"}]}},"_links":{"self":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/53078","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/users\/133"}],"replies":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/comments?post=53078"}],"version-history":[{"count":0,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/posts\/53078\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media\/53084"}],"wp:attachment":[{"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/media?parent=53078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/categories?post=53078"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/tags?post=53078"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.singlecare.com\/blog\/wp-json\/wp\/v2\/coauthors?post=53078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}