{"id":53147,"date":"2022-08-17T10:24:30","date_gmt":"2022-08-17T14:24:30","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53147"},"modified":"2025-12-05T15:25:40","modified_gmt":"2025-12-05T20:25:40","slug":"hydrochlorothiazide-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/hydrochlorothiazide-side-effects\/","title":{"rendered":"What to expect on hydrochlorothiazide"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Hydrochlorothiazide (HCTZ<\/span><span style=\"font-weight: 400;\">) is a generic drug prescribed to lower <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">blood pressure<\/span><\/a><span style=\"font-weight: 400;\">. It is also used to reduce swelling of the legs due to <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/congestive-heart-failure-treatment-and-medications\"><span style=\"font-weight: 400;\">congestive heart failure<\/span><\/a><span style=\"font-weight: 400;\">, ascites, or treatment with corticosteroids or estrogen. As a <\/span><span style=\"font-weight: 400;\">thiazide diuretic<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">water pill<\/span><span style=\"font-weight: 400;\">), <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> increases the elimination of water and salt in the urine. This helps to decrease blood pressure. Many of <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">\u2019s <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> are due to its <\/span><span style=\"font-weight: 400;\">diuretic<\/span><span style=\"font-weight: 400;\"> effects. Some <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> are avoidable, some can be minimized, and others may require medical intervention.<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Hydrochlorothiazide with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tHydrochlorothiazide 25 mg (30 Tablets)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$4.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$4.00<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/hydrochlorothiazide#blog-cta\" class=\"coupon-see-all-btn\">See Hydrochlorothiazide prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"common-side-effects-of-hydrochlorothiazide\"><span style=\"font-weight: 400;\">Common side effects of hydrochlorothiazide<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><span style=\"font-weight: 400;\">common side effect of hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> is <\/span><span style=\"font-weight: 400;\">low potassium levels<\/span><span style=\"font-weight: 400;\">, a direct effect of the drug\u2019s <\/span><span style=\"font-weight: 400;\">diuretic<\/span><span style=\"font-weight: 400;\"> effects. Anywhere from <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Microzide-hydrochlorothiazide-2130.1099\"><span style=\"font-weight: 400;\">one-third to half<\/span><\/a><span style=\"font-weight: 400;\"> of people taking <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> will eventually develop low <\/span><span style=\"font-weight: 400;\">potassium<\/span><span style=\"font-weight: 400;\"> levels (as indicated on a blood lab report). Many of the other <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> are also related to the body\u2019s increased elimination of water and electrolytes:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low <\/span><span style=\"font-weight: 400;\">potassium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low sodium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low magnesium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated <\/span><span style=\"font-weight: 400;\">calcium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low chloride<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated <\/span><span style=\"font-weight: 400;\">blood sugar<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated <\/span><span style=\"font-weight: 400;\">cholesterol<\/span><span style=\"font-weight: 400;\"> and fat levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated uric acid levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Orthostatic hypotension (dizziness and vertigo when standing)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hair loss<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<\/ul>\n<h2 id=\"serious-hctz-side-effects\"><span style=\"font-weight: 400;\">Serious HCTZ side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide\u2019s most <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dangerously <\/span><span style=\"font-weight: 400;\">low potassium levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Electrolyte imbalance<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sun sensitivity<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abnormal heartbeats<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/pancreatitis-treatment-and-medications\"><span style=\"font-weight: 400;\">Inflamed pancreas<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin cancer<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney <\/span><span style=\"font-weight: 400;\">dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anemia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low white blood cell counts (which decreases the body\u2019s ability to fight infection)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low platelet levels (which can cause easy bruising or bleeding)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Angle-closure <\/span><span style=\"font-weight: 400;\">glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Worsening of lupus<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe <\/span><span style=\"font-weight: 400;\">allergic reactions <\/span><span style=\"font-weight: 400;\">or serious skin reactions<\/span><\/li>\n<\/ul>\n<h3 id=\"weight-changes\"><span style=\"font-weight: 400;\">Weight changes<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> eliminates more water from the body than usual, which can lead to a decrease in body weight. That\u2019s nice to see on a bathroom scale, but it isn\u2019t fat or muscle weight. It\u2019s water weight. When <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> is stopped, the water weight will probably return in short order.<\/span><\/p>\n<h3 id=\"electrolyte-imbalance\"><span style=\"font-weight: 400;\">Electrolyte imbalance<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Electrolyte imbalances<\/span><span style=\"font-weight: 400;\"> are a common and may be a <\/span><span style=\"font-weight: 400;\">serious side effect of hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">. The drug can deplete the body of one or more electrolytes including sodium, <\/span><span style=\"font-weight: 400;\">potassium<\/span><span style=\"font-weight: 400;\">, magnesium, and chloride. It can also increase <\/span><span style=\"font-weight: 400;\">calcium<\/span><span style=\"font-weight: 400;\"> levels. The effects seem to be dose-related. While the incidence of electrolyte problems has not been determined, they are common enough that people taking <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> need to be periodically tested for electrolyte levels, particularly <\/span><span style=\"font-weight: 400;\">potassium with a common blood test<\/span><span style=\"font-weight: 400;\">. People taking <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> should know the signs of electrolyte depletion, particular hypokalemia, or low <\/span><span style=\"font-weight: 400;\">potassium<\/span><span style=\"font-weight: 400;\">, such as weakness, fatigue, muscle cramps, and constipation. Contact a <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\"> if any of these symptoms are noticed.<\/span><\/p>\n<h3 id=\"sun-sensitivity\"><span style=\"font-weight: 400;\">Sun sensitivity<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide is associated with an increased risk of certain skin cancers. The medication causes sun sensitivity. Patients who take hydrochlorothiazide should visit their dermatologist on a regular basis for skin cancer screenings. Also, people who take this drug should avoid tanning beds, and avoid the sun when possible. When in the sun, it is important to wear protective clothing and apply and reapply sunscreen (of at least SPF 30) frequently.<\/span><\/p>\n<h3 id=\"severe-allergic-or-skin-reactions\"><span style=\"font-weight: 400;\">Severe allergic or skin reactions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In rare cases, a serious allergic or skin reaction may occur. These reactions can be life-threatening or cause death. If you notice any of the following symptoms, get emergency medical help right away. Symptoms of a serious allergic reaction can include <\/span><span style=\"font-weight: 400;\">hives<\/span><span style=\"font-weight: 400;\">, difficulty breathing, or swelling of the face, lips, tongue, or throat. Symptoms of a serious skin reaction may include sore throat, fever, burning eyes, red or purple rash, or blistering or peeling skin.\u00a0<\/span><\/p>\n<h3 id=\"chest-pain\"><span style=\"font-weight: 400;\">Chest pain<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> has not been associated with causing or worsening <\/span><span style=\"font-weight: 400;\">chest pain<\/span><span style=\"font-weight: 400;\">. However, it is frequently combined with other blood pressure drugs that may worsen <\/span><span style=\"font-weight: 400;\">chest pain<\/span><span style=\"font-weight: 400;\">. When taking more than one <\/span><span style=\"font-weight: 400;\">prescription drug<\/span><span style=\"font-weight: 400;\">, it\u2019s sometimes difficult to determine which drug is responsible for individual <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Chest pain<\/span><span style=\"font-weight: 400;\"> is a potentially serious symptom, so make sure to tell the prescribing <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider.<\/span><\/p>\n<h3 id=\"joint-pain\"><span style=\"font-weight: 400;\">Joint pain\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Joint pain is not a <\/span><span style=\"font-weight: 400;\">side effect of hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">. However, the drug can worsen some types of existing joint diseases. Because <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> reduces the fluid volume of blood, it results in a percentage increase of other substances in the blood like uric acid. If uric acid levels get high enough, the excess crystallizes in the joints. This can cause or worsen <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/gout-treatment-and-medications\"><span style=\"font-weight: 400;\">gout<\/span><\/a><span style=\"font-weight: 400;\">, an arthritic condition due to uric acid crystals building up in the joints. How often <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> contributes to gout flare-ups is <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Microzide-hydrochlorothiazide-2130.1099\"><span style=\"font-weight: 400;\">unknown<\/span><\/a><span style=\"font-weight: 400;\">, but the joint pain is certainly painful and sometimes debilitating.<\/span><\/p>\n<h3 id=\"hair-loss\"><span style=\"font-weight: 400;\">Hair loss\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Thinning hair is a <\/span><span style=\"font-weight: 400;\">side effect<\/span><span style=\"font-weight: 400;\"> of <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/thiazide-diuretics\"><span style=\"font-weight: 400;\">thiazide diuretics<\/span><\/a><span style=\"font-weight: 400;\">. The hair loss won\u2019t happen all at once as it does with some drugs, such as cancer drugs. Instead, it will take <\/span><a href=\"https:\/\/link.springer.com\/article\/10.2165\/00002018-199410040-00005\"><span style=\"font-weight: 400;\">a few months<\/span><\/a><span style=\"font-weight: 400;\">. The incidence is unknown, but remember that <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> is typically used with other blood pressure drugs. One type of blood pressure drug, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/beta-blockers\"><span style=\"font-weight: 400;\">beta blockers<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/7631289\/\"><span style=\"font-weight: 400;\">are also associated<\/span><\/a><span style=\"font-weight: 400;\"> with hair loss and hair thinning. The good news is that drug-induced hair loss is usually reversible once the offending drug has been stopped.\u00a0<\/span><\/p>\n<h2 id=\"hydrochlorothiazide-side-effects-by-dosage\"><span style=\"font-weight: 400;\">Hydrochlorothiazide side effects by dosage<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide is usually dosed once daily or sometimes twice daily. Increased daily dosage of hydrochlorothiazide can increase the risk of electrolyte disturbances and dehydration. When given for hypertension, HCTZ doses are rarely above 50 mg a day. However, when used for the treatment of swelling of extremities, HCTZ doses may be as high as 100 mg per day, which increases the risk of side effects.<\/span><\/p>\n<h2 id=\"how-soon-do-hydrochlorothiazide-side-effects-start\"><span style=\"font-weight: 400;\">How soon do <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span> <span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">\u2019s <\/span><span style=\"font-weight: 400;\">diuretic<\/span><span style=\"font-weight: 400;\"> effects begin within an hour or two of taking the capsule or tablet and peak in one to five hours. Some <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> may occur during this time, including diarrhea, nausea, and vomiting. <\/span><span style=\"font-weight: 400;\">Allergic reactions<\/span><span style=\"font-weight: 400;\">, however, can occur very rapidly, even after taking the first dose. Many other <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> are delayed and could take days, weeks, or months to manifest.<\/span><\/p>\n<h2 id=\"how-long-do-hydrochlorothiazide-side-effects-last\"><span style=\"font-weight: 400;\">How long do <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span> <span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The body will adapt to <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">, so some <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> may lessen over time as you get used to the medicine. Those that don\u2019t will mostly resolve after the drug has been stopped, particularly the most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\">. Even hair loss is often reversible when caused by drugs like <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2 id=\"what-are-the-long-term-side-effects-of-hydrochlorothiazide\"><span style=\"font-weight: 400;\">What are the long-term <\/span><span style=\"font-weight: 400;\">side effects of hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most of <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">\u2019s <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> will get better after the drug has been stopped. Some conditions may require time to improve, such as <\/span><span style=\"font-weight: 400;\">allergic reactions<\/span><span style=\"font-weight: 400;\"> or gout. Some <\/span><span style=\"font-weight: 400;\">side effects,<\/span><span style=\"font-weight: 400;\"> such as <\/span><span style=\"font-weight: 400;\">skin cancer<\/span><span style=\"font-weight: 400;\"> or kidney damage, may have long-term or lifelong consequences.<\/span><\/p>\n<h2 id=\"hydrochlorothiazide-contraindications\"><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">You should not take hydrochlorothiazide if you have:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems or can\u2019t make urine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">An allergy to hydrochlorothiazide or sulfa drugs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A newborn with jaundice (if breastfeeding)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Use caution or talk to your provider if you\u2019re pregnant, breastfeeding, or taking other medications.<\/span><\/p>\n<h2 id=\"hydrochlorothiazide-warnings\"><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Like all <\/span><span style=\"font-weight: 400;\">diuretics<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> may cause problems due to pre-existing health conditions or other underlying issues.<\/span><\/p>\n<h3 id=\"cautions\"><span style=\"font-weight: 400;\">Cautions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> can cause problems in people with certain <\/span><span style=\"font-weight: 400;\">medical conditions<\/span><span style=\"font-weight: 400;\">. In some cases, <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> may worsen conditions such as gout or trigger a recurrence, like pancreatitis. These medical or physical conditions include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Electrolyte problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dehydration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of gout<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of pancreatitis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver or kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Irregular heartbeats<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/lupus-treatment-and-medications\"><span style=\"font-weight: 400;\">Lupus<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Additionally, <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> may cause issues in older patients, including low sodium levels and falls. Finally, the risk for non-melanoma <\/span><span style=\"font-weight: 400;\">skin cancer<\/span><span style=\"font-weight: 400;\"> goes up when taking <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">, a risk that is greatest for caucasian patients.<\/span><\/p>\n<h3 id=\"abuse-and-dependence\"><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> is not associated with drug abuse, dependence, or withdrawal.<\/span><\/p>\n<h3 id=\"overdose\"><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> overdose can cause a hazardous depletion of electrolytes, so immediate medical care is needed if an overdose is suspected. The symptoms of an overdose may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Muscle pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><span style=\"font-weight: 400;\">\/thirst<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The maximum dosage will depend on age and the condition being treated. The <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Microzide-hydrochlorothiazide-2130#6\"><span style=\"font-weight: 400;\">maximum adult dose<\/span><\/a><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">hypertension<\/span><span style=\"font-weight: 400;\"> is 50 mg per day; for <\/span><span style=\"font-weight: 400;\">fluid retention<\/span><span style=\"font-weight: 400;\">, the maximum daily dose is 100 mg.<\/span><\/p>\n<h3 id=\"recalls\"><span style=\"font-weight: 400;\">Recalls<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> recalls are rare and limited to quality issues at individual manufacturing centers.<\/span><\/p>\n<h2 id=\"hydrochlorothiazide-interactions\"><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">People <\/span><span style=\"font-weight: 400;\">using hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> often take other drugs. Some of these can be risky when taken with <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other <\/span><b>blood pressure medications<\/b><span style=\"font-weight: 400;\">, though commonly prescribed with <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\">, increase the risk of <\/span><span style=\"font-weight: 400;\">low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Corticosteroids<\/b><span style=\"font-weight: 400;\"> such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prednisone\"><span style=\"font-weight: 400;\">prednisone<\/span><\/a><span style=\"font-weight: 400;\"> increase the risk of electrolyte loss when taking <\/span><span style=\"font-weight: 400;\">thiazide diuretics<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Bile resins<\/b><span style=\"font-weight: 400;\"> (such as cholestyramine) can make it harder for the body to absorb <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Antidiabetic drugs<\/b><span style=\"font-weight: 400;\"> may be less effective because <\/span><span style=\"font-weight: 400;\">thiazide diuretics<\/span><span style=\"font-weight: 400;\"> can increase <\/span><span style=\"font-weight: 400;\">blood sugar<\/span><span style=\"font-weight: 400;\"> levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nonsteroidal anti-inflammatory drugs<\/b><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/a><span style=\"font-weight: 400;\">) such as aspirin, <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">, and <\/span><span style=\"font-weight: 400;\">naproxen<\/span><span style=\"font-weight: 400;\"> may reduce the effectiveness of <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> and increase the risk of kidney damage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some drugs, like <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/aminoglycosides\"><b>aminoglycoside antibiotics<\/b><\/a> <span style=\"font-weight: 400;\">and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lithium-carbonate\"><b>lithium<\/b><\/a><span style=\"font-weight: 400;\">, can damage the kidneys; they are more likely to damage the kidneys when taken with a <\/span><span style=\"font-weight: 400;\">diuretic<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Barbiturates<\/b><span style=\"font-weight: 400;\">, <\/span><b>sedatives<\/b><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/opioids\"><b>opioids<\/b><\/a><span style=\"font-weight: 400;\"> increase the risk of orthostatic hypotension and, as a result, may increase the risks of accidents, fainting, and falls<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Stimulants <\/b><span style=\"font-weight: 400;\">(such as Adderall) can increase blood pressure, which may decrease <\/span><span style=\"font-weight: 400;\">the<\/span><span style=\"font-weight: 400;\"> effectiveness of hydrochlorothiazide in lowering blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/marplan\"><b>Marplan<\/b><\/a><b> (isocarboxazid)<\/b><span style=\"font-weight: 400;\">, an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antidepressants\"><span style=\"font-weight: 400;\">antidepressant<\/span><\/a><span style=\"font-weight: 400;\"> in the monoamine oxidase inhibitor (MAOI) drug class, is never given with drugs that lower blood pressure, because the combination could cause a dangerous drop in blood pressure. Other medications in the MAOI class can have the same effect and should not be taken with hydrochlorothiazide<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Foods and drinks to avoid when taking hydrochlorothiazide include alcohol, excessive amounts of caffeine, and <\/span><span style=\"font-weight: 400;\">diuretic<\/span><span style=\"font-weight: 400;\"> herbs like dandelion, hibiscus, or green tea.\u00a0<\/span><\/p>\n<h2 id=\"how-to-avoid-hydrochlorothiazide-side-effects\"><span style=\"font-weight: 400;\">How to avoid <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span> <span style=\"font-weight: 400;\">side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Diuretics<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> often involve unwanted <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\">, but they are important tools in fighting <\/span><span style=\"font-weight: 400;\">high blood pressure<\/span><span style=\"font-weight: 400;\">. A few guidelines can help both to minimize <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> and maximize the drug\u2019s benefits.\u00a0<\/span><\/p>\n<h3 id=\"1-take-hydrochlorothiazide-as-directed\"><span style=\"font-weight: 400;\">1. Take <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Follow all directions provided by the prescriber or printed on the prescription label. The standard dose is 12.5\u201350 mg per day for <\/span><span style=\"font-weight: 400;\">hypertension<\/span><span style=\"font-weight: 400;\"> and 25\u2013100 mg daily for <\/span><span style=\"font-weight: 400;\">edema<\/span><span style=\"font-weight: 400;\">. Generally, it is best to take hydrochlorothiazide in the morning. This is because it makes you urinate, and taking it at night may disrupt your sleep.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">What if you miss a dose of hydrochlorothiazide? If a dose is missed, take it as soon as you remember. However, if it\u2019s almost time for the <\/span><span style=\"font-weight: 400;\">next dose<\/span><span style=\"font-weight: 400;\">, skip the <\/span><span style=\"font-weight: 400;\">missed dose and continue with your regular schedule<\/span><span style=\"font-weight: 400;\">. Take the next scheduled dose at the regular time. Do not double the dose to try to make up for a missed dose.\u00a0<\/span><\/p>\n<h3 id=\"2-give-the-prescriber-a-complete-medical-history\"><span style=\"font-weight: 400;\">2. Give the prescriber a complete medical history<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The most worrisome <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> involve worsening existing <\/span><span style=\"font-weight: 400;\">medical conditions<\/span><span style=\"font-weight: 400;\">, so make sure the prescribing <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider has an entire medical history, especially:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gout<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low <\/span><span style=\"font-weight: 400;\">potassium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High <\/span><span style=\"font-weight: 400;\">calcium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Narrow angles in the eyes or a history of <\/span><span style=\"font-weight: 400;\">glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizure disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart rate<\/span><span style=\"font-weight: 400;\"> problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any upcoming parathyroid tests<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy, anticipated pregnancy, or <\/span><span style=\"font-weight: 400;\">breastfeeding<\/span><\/li>\n<\/ul>\n<h3 id=\"3-give-the-prescriber-a-list-of-all-drugs-being-taken\"><span style=\"font-weight: 400;\">3. Give the prescriber a list of all drugs being taken<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drug interactions<\/span><span style=\"font-weight: 400;\"> are another significant source of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">, so make sure the prescribing <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider has a complete picture of the <\/span><span style=\"font-weight: 400;\">prescription drugs<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span><span style=\"font-weight: 400;\"> medications, and vitamins or dietary <\/span><span style=\"font-weight: 400;\">supplements<\/span><span style=\"font-weight: 400;\"> being taken, particularly:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood pressure medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">Corticosteroids<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bile resins such as <\/span><span style=\"font-weight: 400;\">cholestyramine<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">colestipol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lithium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NSAIDs<\/span><\/li>\n<\/ul>\n<h3 id=\"4-do-not-miss-follow-up-appointments-or-lab-tests\"><span style=\"font-weight: 400;\">4. Do not miss follow-up appointments or lab tests<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Staying safe on <\/span><span style=\"font-weight: 400;\">diuretics<\/span><span style=\"font-weight: 400;\"> may require follow-up visits and tests. In this way, <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> can be corrected before they become hazardous.\u00a0<\/span><\/p>\n<h3 id=\"5-drink-plenty-of-fluids\"><span style=\"font-weight: 400;\">5. Drink plenty of fluids<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid dehydration, drink plenty of clear (not salty) fluids throughout the day. Avoid going outside if it\u2019s hot. If <\/span><span style=\"font-weight: 400;\">hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> is being used to treat <\/span><span style=\"font-weight: 400;\">fluid retention<\/span><span style=\"font-weight: 400;\">, follow the fluid restrictions given by the prescribing <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> provider.<\/span><\/p>\n<h3 id=\"6-avoid-laxatives\"><span style=\"font-weight: 400;\">6. Avoid laxatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Laxatives can cause dehydration. The risk is even greater when taking <\/span><span style=\"font-weight: 400;\">diuretics<\/span><span style=\"font-weight: 400;\">. The best advice is not to use laxatives casually when taking <\/span><span style=\"font-weight: 400;\">diuretics<\/span><span style=\"font-weight: 400;\">. If <\/span><span style=\"font-weight: 400;\">constipation<\/span><span style=\"font-weight: 400;\"> is a problem, consult a healthcare provider for the most suitable treatment.<\/span><\/p>\n<h3 id=\"7-skip-the-calcium-supplements\"><span style=\"font-weight: 400;\">7. Skip the <\/span><span style=\"font-weight: 400;\">calcium<\/span> <span style=\"font-weight: 400;\">supplements<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> can increase <\/span><span style=\"font-weight: 400;\">calcium<\/span><span style=\"font-weight: 400;\"> levels in the body. If you are taking <\/span><span style=\"font-weight: 400;\">calcium<\/span><span style=\"font-weight: 400;\"> or vitamin D <\/span><span style=\"font-weight: 400;\">supplements<\/span><span style=\"font-weight: 400;\">, discuss with your prescriber whether to continue them.<\/span><\/p>\n<h3 id=\"8-avoid-taking-a-late-dose\"><span style=\"font-weight: 400;\">8. Avoid taking a late dose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> can be taken at any time of day, but if taken late, it could interfere with sleep by requiring frequent trips to the bathroom. Most people prefer to take hydrochlorothiazide in the morning.<\/span><\/p>\n<h3 id=\"9-use-sunblock\"><span style=\"font-weight: 400;\">9. Use sunblock<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Hydrochlorothiazide<\/span><span style=\"font-weight: 400;\"> increases the risk of developing non-melanoma <\/span><span style=\"font-weight: 400;\">skin cancer<\/span><span style=\"font-weight: 400;\">. That risk approximately triples for people with fair skin. Avoid the sun. If it\u2019s unavoidable, use a high SPF sunscreen and reapply it frequently, especially when swimming and\/or sweating.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects-of-hydrochlorothiazide\"><span style=\"font-weight: 400;\">How to treat <\/span><span style=\"font-weight: 400;\">side effects of hydrochlorothiazide<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you notice any of these symptoms, here&#8217;s what to do:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Dizziness:<\/b><span style=\"font-weight: 400;\"> Sit or lie down immediately. Stand up slowly.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Dehydration:<\/b><span style=\"font-weight: 400;\"> Sip water or electrolyte drinks and call your provider.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Electrolyte issues:<\/b><span style=\"font-weight: 400;\"> Be aware of muscle cramps, fatigue, or irregular heartbeats. Contact a provider.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Vision changes or eye pain:<\/b><span style=\"font-weight: 400;\"> Get emergency help immediately.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Allergic reactions:<\/b><span style=\"font-weight: 400;\"> Seek emergency care for swelling, hives, or skin blistering<\/span><\/li>\n<\/ul>\n<h2 id=\"when-to-see-your-healthcare-provider-about-hctz-side-effects\"><span style=\"font-weight: 400;\">When to see your healthcare provider about HCTZ side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Symptoms that require immediate medical attention include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe cramping during the day or that wakes you at night<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Hydrochlorothiazide (HCTZ) is a generic drug prescribed to lower blood pressure. It is also used to reduce swelling of the legs due to congestive heart failure, ascites, or treatment with corticosteroids or estrogen. As a thiazide diuretic (water pill), hydrochlorothiazide increases the elimination of water and salt in the urine. This helps to decrease blood [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":53153,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[737,12752],"coauthors":[8861],"class_list":["post-53147","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-heart-health","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>What to expect on hydrochlorothiazide<\/title>\n<meta name=\"description\" content=\"Weight changes, electrolyte imbalance, and sun sensitivity are common hydrochlorothiazide side effects. 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