{"id":53159,"date":"2022-08-15T10:30:40","date_gmt":"2022-08-15T14:30:40","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53159"},"modified":"2022-08-15T10:30:40","modified_gmt":"2022-08-15T14:30:40","slug":"ibuprofen-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/ibuprofen-side-effects\/","title":{"rendered":"Ibuprofen side effects and how to avoid them"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#common-ibuprofen-side-effects\"> Common ibuprofen side effects<\/a> | <a href=\"#serious-side-effects\">Serious side effects <\/a><\/span><span style=\"font-weight: 400;\">| <a href=\"#high-blood-pressure\">High blood pressure<\/a> | <a href=\"#acute-kidney-injury\">Acute kidney injury<\/a> | <a href=\"#stomach-ulcers\">Stomach ulcers<\/a> | <a href=\"#side-effects-timeline\">Side effects timeline<\/a><\/span><span style=\"font-weight: 400;\"> | <a href=\"#contraindications\">Contraindications<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a><\/span><span style=\"font-weight: 400;\"> | <a href=\"#how-to-treat-side-effects\">How to treat side effects<\/a><\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/ibuprofen\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><\/a><span style=\"font-weight: 400;\"> is a common <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span> <a href=\"https:\/\/www.singlecare.com\/drug-classes\/analgesics\"><span style=\"font-weight: 400;\">pain reliever<\/span><\/a><span style=\"font-weight: 400;\"> and fever reducer that is safe for most adults, children, and infants to use for <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=844c1047-9de5-4f47-b7cc-efb1928c21d8\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">mild to <\/span><span style=\"font-weight: 400;\">moderate pain<\/span><span style=\"font-weight: 400;\"> or fever<\/span><\/a><span style=\"font-weight: 400;\">. Widely available as a generic, <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is also instantly recognizable under the <\/span><span style=\"font-weight: 400;\">brand names<\/span> <a href=\"https:\/\/www.singlecare.com\/prescription\/advil\"><span style=\"font-weight: 400;\">Advil<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/motrin-ib\"><span style=\"font-weight: 400;\">Motrin<\/span><\/a><span style=\"font-weight: 400;\">. Healthcare providers may prescribe high-dose <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">\u2014called <\/span><span style=\"font-weight: 400;\">IBU<\/span><span style=\"font-weight: 400;\">\u2014for juvenile <\/span><span style=\"font-weight: 400;\">rheumatoid arthritis<\/span><span style=\"font-weight: 400;\">, osteoarthritis, and <\/span><span style=\"font-weight: 400;\">menstrual cramps<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> belongs to a family of drugs called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nsaids\"><span style=\"font-weight: 400;\">nonsteroidal anti-inflammatory drugs<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\">). These drugs block inflammation at the source by preventing the production of substances called prostaglandins, the chemicals responsible for swelling. <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> are very effective but can have unwanted <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\">. Knowing what to expect can help keep problems at arms-length.<\/span><\/p>\n<h2 id=\"common-ibuprofen-side-effects\"><span style=\"font-weight: 400;\">Common side effects of ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Digestive system problems are by far the most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> people experience when taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. Here are the most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/23305\/ibuprofen\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\"> in <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Ibuprofen-Tablets-ibuprofen-2618\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">order of incidence<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heartburn<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gassiness and flatulence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ringing in the ears<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Changes in potassium levels<\/span><\/li>\n<\/ul>\n<h2 id=\"serious-side-effects\"><span style=\"font-weight: 400;\">Serious side effects of ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Even though <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> can be purchased without a prescription, it can have serious and even life-threatening <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">, particularly if it\u2019s overused. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anemia<\/span><span style=\"font-weight: 400;\"> and other blood disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prolonged bleeding or easy bruising<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding, <\/span><span style=\"font-weight: 400;\">ulcers<\/span><span style=\"font-weight: 400;\">, or perforations in the stomach or intestines<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/pancreatitis-treatment-and-medications\"><span style=\"font-weight: 400;\">Swelling of the pancreas<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood clots<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Congestive <\/span><span style=\"font-weight: 400;\">heart failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver poisoning, liver damage, or liver failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney poisoning, kidney damage, or kidney failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/asthma-treatment-and-medications\"><span style=\"font-weight: 400;\">Asthma attacks<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eye damage or visual impairment<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hearing loss\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe and potentially life-threatening <\/span><span style=\"font-weight: 400;\">allergic reactions<\/span><span style=\"font-weight: 400;\"> such as anaphylaxis, drug reactions, or severe skin reactions<\/span><\/li>\n<\/ul>\n<h3 id=\"high-blood-pressure\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Like all <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> can worsen hypertension. However, less than one percent of people taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> will see a clinically significant rise in blood pressure. People being treated for hypertension are particularly at risk, so they should monitor their blood pressure when taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"acute-kidney-injury\"><span style=\"font-weight: 400;\">Acute kidney injury<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">All <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> can be toxic to the kidneys, including shelf-bought <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. The incidence has not been determined, but those most at risk include people with existing <\/span><span style=\"font-weight: 400;\">kidney disease<\/span><span style=\"font-weight: 400;\">, older patients, and anyone taking other drugs that can poison the kidneys. The best advice is to talk to a primary healthcare provider who can give <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> about whether <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> are safe to take.\u00a0<\/span><\/p>\n<h3 id=\"stomach-ulcers\"><span style=\"font-weight: 400;\">Stomach <\/span><span style=\"font-weight: 400;\">ulcers<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> work by preventing the body from making prostaglandins. This helps prevent swelling, but prostaglandins also protect the stomach lining from the burning acid splashing around inside. No surprise, then, that <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> complaints are common with <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. If prostaglandins are blocked for too long, the stomach acid will wear away the stomach lining and create sores (<\/span><span style=\"font-weight: 400;\">ulcers<\/span><span style=\"font-weight: 400;\">). <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/ulcer-treatment-and-medications\"><span style=\"font-weight: 400;\">Peptic <\/span><span style=\"font-weight: 400;\">ulcers<\/span><\/a><span style=\"font-weight: 400;\"> occur in less than one percent of people taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">, but people who have this problem are most likely taking too much <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"side-effects-timeline\"><span style=\"font-weight: 400;\">How soon do <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span> <span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many of the most <\/span><span style=\"font-weight: 400;\">common side effects of ibuprofen<\/span><span style=\"font-weight: 400;\"> can start as early as the first dose. These include minor <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> issues, rash, itching, and headache. Some <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> may require taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> for a while, like ringing in the ears, <\/span><span style=\"font-weight: 400;\">constipation<\/span><span style=\"font-weight: 400;\">, and liver problems. Other <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">, especially the more serious ones, usually require chronic use of <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> to become a problem.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How long do <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span> <span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span> <span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> clear up when a person stops taking the medicine. <\/span><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> has a short half-life of about 2 hours, so a dose is undetectable in about 10 to 12 hours. That\u2019s about the time it takes for <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">-induced problems like stomach ache, nausea, indigestion, rash, headache, and other mild issues to clear up.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What are the long-term <\/span><span style=\"font-weight: 400;\">side effects of ibuprofen<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ibuprofen,<\/span><span style=\"font-weight: 400;\"> like other <\/span><span style=\"font-weight: 400;\">NSAIDs,<\/span><span style=\"font-weight: 400;\"> is not intended for constant use. Some of the most <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\"> other than <\/span><span style=\"font-weight: 400;\">allergic reactions<\/span><span style=\"font-weight: 400;\"> are primarily experienced in people who overuse <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Side effects<\/span><span style=\"font-weight: 400;\"> due to overdosing or chronic overuse of <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> usually take longer to get better after the drug has been stopped. These include <\/span><span style=\"font-weight: 400;\">anemia<\/span><span style=\"font-weight: 400;\">, blood disorders, and serious <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> issues. The most severe <\/span><span style=\"font-weight: 400;\">adverse effects,<\/span><span style=\"font-weight: 400;\"> such as <\/span><span style=\"font-weight: 400;\">heart attack<\/span><span style=\"font-weight: 400;\">, stroke, and GI perforation, could have long-term or lifelong consequences. Some effects, like kidney damage or liver damage, may be permanent.<\/span><\/p>\n<h2 id=\"contraindications\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> should never be taken by anyone with the following health conditions:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Known allergies to <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> or other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of aspirin-induced or <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\">-induced asthma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of aspirin-induced or <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\">-induced <\/span><span style=\"font-weight: 400;\">hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aspirin-exacerbated respiratory disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe <\/span><span style=\"font-weight: 400;\">kidney disease<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> and other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> should not be taken immediately before or after coronary artery bypass graft (CABG) surgery.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Pregnancy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> and other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> should be avoided in the third trimester to prevent possible serious health issues in newborns. Because <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> can also cause problems with amniotic fluid and the fetus\u2019s kidneys, <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> use is discouraged between weeks 20 and 29 of a pregnancy. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/acetaminophen\"><span style=\"font-weight: 400;\">Acetaminophen<\/span><\/a><span style=\"font-weight: 400;\"> is the preferred <\/span><span style=\"font-weight: 400;\">pain relief<\/span><span style=\"font-weight: 400;\"> medication and fever reducer for pregnant women.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Breastfeeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> is considered a preferred pain reliever in women who are nursing. Very little of it shows up in breast milk, and no problems have been reported in nursing infants.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> is <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">-approved for use in children as young as 6 months. Dosing will be determined by weight, so make sure to purchase the age-appropriate format for infants or children before giving a dose.<\/span><\/p>\n<h2 id=\"warnings\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Although sold <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> like <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> are powerful medications that affect many systems in the body. They should be used cautiously and judiciously rather than just pulled from the shelf and swallowed. Here are some potential problems.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Black box warning<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Every <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> package includes a black box warning from the <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\"> cautioning users that the drug could cause <\/span><span style=\"font-weight: 400;\">blood clots<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> bleeding, <\/span><span style=\"font-weight: 400;\">ulcers<\/span><span style=\"font-weight: 400;\">, and <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> perforation. <\/span><span style=\"font-weight: 400;\">Blood clots<\/span><span style=\"font-weight: 400;\"> can be serious enough to cause life-threatening <\/span><span style=\"font-weight: 400;\">cardiovascular<\/span><span style=\"font-weight: 400;\"> problems, including <\/span><span style=\"font-weight: 400;\">heart attack<\/span><span style=\"font-weight: 400;\"> and stroke.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Cautions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Pre-existing medical conditions could be worsened when taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. This doesn\u2019t mean <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is dangerous, but people with these conditions should use the lowest possible dose and pay attention to any problems that may arise. These conditions include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart problems including <\/span><span style=\"font-weight: 400;\">heart failure<\/span><span style=\"font-weight: 400;\"> or any recent <\/span><span style=\"font-weight: 400;\">heart attack<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Risk factors<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">heart disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Digestive system problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bleeding disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fluid retention<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dehydration<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Women trying to conceive<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> may cause fertility problems in women, so <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> and other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> are best avoided when trying to get pregnant<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Seniors and debilitated patients have an <\/span><span style=\"font-weight: 400;\">increased risk<\/span><span style=\"font-weight: 400;\"> for severe <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\"> when <\/span><span style=\"font-weight: 400;\">using ibuprofen<\/span><span style=\"font-weight: 400;\">, particularly serious <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> problems and kidney dysfunction. Some elderly patients may need to avoid <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> altogether. Others should only take the lowest possible dose for the shortest period.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> is not associated with drug abuse, dependence, or withdrawal.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overuse<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> constantly or in high doses raises the risk of <\/span><span style=\"font-weight: 400;\">serious side effects,<\/span><span style=\"font-weight: 400;\"> including <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> problems, bleeding, <\/span><span style=\"font-weight: 400;\">blood clots<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">heart attack<\/span><span style=\"font-weight: 400;\">, and stroke. Always use the lowest possible dose for the shortest period of time.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Taking too much <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is a potentially serious problem. It can cause significant bleeding issues and even end in a coma. Call a poison helpline or get <\/span><span style=\"font-weight: 400;\">medical attention<\/span><span style=\"font-weight: 400;\"> if too much <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is taken. Symptoms of an <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> overdose include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood in the stools (black, tarry, or bloody stools)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coughing up blood or <\/span><span style=\"font-weight: 400;\">blood clots<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Slow or shallow breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fainting<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The maximum daily dose of <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> for adults is 1,200 mg per day for nonprescription <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. However, people prescribed <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> (or <\/span><span style=\"font-weight: 400;\">IBU<\/span><span style=\"font-weight: 400;\">) are given prescriptions for up to 3,200 mg per day. That does not mean that it\u2019s safe to take 3,200 mg of store-bought <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> in a day! It\u2019s not unless under the supervision of a doctor or other <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"interactions\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">To avoid problems, particularly <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> complaints, bleeding problems, or kidney issues, exercise caution in combining <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> (especially ketorolac, which is contraindicated for use with <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Salicylates (aspirin-like drugs)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">blood pressure medications<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diuretics<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">SSRIs<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticoagulants\"><span style=\"font-weight: 400;\">Blood thinners<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">Corticosteroids<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/drug-classes\/aminoglycosides\"><span style=\"font-weight: 400;\">Aminoglycoside antibiotics<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> has a slight effect on blood pressure, so it may add to the blood pressure raising effects of other drugs, such as stimulants, <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/migraine-treatment-and-medications\"><span style=\"font-weight: 400;\">migraine drugs<\/span><\/a><span style=\"font-weight: 400;\">, and others. If blood pressure is a problem, then make sure to monitor blood pressure when adding <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> to other drugs.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Healthcare providers do not advise people to avoid certain foods when taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. Though not dangerous, some dietary <\/span><span style=\"font-weight: 400;\">supplements<\/span><span style=\"font-weight: 400;\"> affect bleeding, like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/garlic-oil\"><span style=\"font-weight: 400;\">garlic oil<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/krill-oil\"><span style=\"font-weight: 400;\">krill oil<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/omega-3\"><span style=\"font-weight: 400;\">omega-3<\/span><\/a><span style=\"font-weight: 400;\"> fatty acids. If bleeding and bruising are a problem, consider taking a break from these <\/span><span style=\"font-weight: 400;\">supplements<\/span><span style=\"font-weight: 400;\"> when taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both smoking and drinking raise the risk of <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> causing <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> issues, including bleeding and <\/span><span style=\"font-weight: 400;\">ulcers<\/span><span style=\"font-weight: 400;\">, so it may be a good idea to cut back. It\u2019s okay to drink moderately, but avoid drinking to excess.<\/span><\/p>\n<h2 id=\"how-to-avoid-side-effects\"><span style=\"font-weight: 400;\">How to avoid <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span> <span style=\"font-weight: 400;\">side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As an <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span><span style=\"font-weight: 400;\"> medication, <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is generally safe for people to take as directed. Most will experience no or only very minor <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">. Here\u2019s some advice to ward off some of the more unpleasant <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">:<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">1. Take <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Follow all the instructions on the package or package insert. Don\u2019t take extra medicine. Make sure to understand the minimum amount of time that has to pass between doses.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">2. Avoid other <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Combining more than one <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\">\u2014a drug class that includes <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aspirin\"><span style=\"font-weight: 400;\">aspirin<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/naproxen\"><span style=\"font-weight: 400;\">naproxen<\/span><\/a><span style=\"font-weight: 400;\">\u2014will increase the risk of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">, including the more serious ones like bleeding. Don\u2019t take more than one <\/span><span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\"> at a time. It\u2019s tricky, though, because some <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span><span style=\"font-weight: 400;\"> combination drugs, like cold and flu medicine, may contain aspirin or <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">. Always read the ingredients on combination drugs before using them.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3. Don\u2019t keep taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> long-term<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Most of <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">\u2019s worst <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> are a result of using the drug too much. If pain is so bad that it requires continual doses of <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">, get <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> from a <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\"> about alternative treatments.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Take <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> with food<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid <\/span><span style=\"font-weight: 400;\">stomach pain<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">heartburn<\/span><span style=\"font-weight: 400;\">, eat a snack or meal before taking an <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> dose.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">5. Avoid smoking and alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drinking alcohol and smoking increase the risk for <\/span><span style=\"font-weight: 400;\">gastrointestinal<\/span><span style=\"font-weight: 400;\"> problems, including bleeding and stomach <\/span><span style=\"font-weight: 400;\">ulcers<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">6. Always ask about using <\/span><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> with new prescriptions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ibuprofen<\/span><span style=\"font-weight: 400;\"> has some <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\"> that can worsen the <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of both drugs. When getting a new prescription, ask the prescriber or pharmacist whether it\u2019s okay to <\/span><span style=\"font-weight: 400;\">use ibuprofen<\/span><span style=\"font-weight: 400;\"> or some other <\/span><span style=\"font-weight: 400;\">over-the-counter<\/span> <span style=\"font-weight: 400;\">NSAID<\/span><span style=\"font-weight: 400;\">. This can help prevent being hit with unexpected, but preventable problems.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">7. Use extra caution when administering <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> to a child<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If dosing a child, follow the dosing instructions very carefully. It\u2019s easy to overdose a young child or infant. Only use the product formulation specific to the child\u2019s age. Consult the dosing chart each time a dose is administered. If it\u2019s in liquid form, shake it well before drawing out a dose. If not, the child might get too much <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> in the last doses drawn from the bottle. Use the measuring device or oral syringe that comes with the medicine, not kitchen tools. Stop giving the medicine when the child feels better.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects\"><span style=\"font-weight: 400;\">How to treat <\/span><span style=\"font-weight: 400;\">side effects of ibuprofen<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">While most people will have few or no problems with <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\">, that doesn\u2019t mean they won\u2019t happen. When they do, here are ways to handle them.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Stomach pain<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If <\/span><span style=\"font-weight: 400;\">stomach upset<\/span><span style=\"font-weight: 400;\"> or pain is a problem, take an antacid before each dose. If that doesn\u2019t help, get <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> from a healthcare provider.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Nausea<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> is causing queasiness, eat simple and plain foods when taking the drug.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Stomach bleeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Stop taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> and get medical help if there\u2019s bleeding in the digestive system. It can only be spotted through its symptoms:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bloody, black, or <\/span><span style=\"font-weight: 400;\">tarry stools<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting up blood or <\/span><span style=\"font-weight: 400;\">blood clots<\/span><span style=\"font-weight: 400;\"> (\u201ccoffee grounds\u201d)<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Kidney problems<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">NSAIDs<\/span><span style=\"font-weight: 400;\"> can cause problems with <\/span><span style=\"font-weight: 400;\">kidney function<\/span><span style=\"font-weight: 400;\">. The signs are not obvious, so stop taking <\/span><span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> and get immediate <\/span><span style=\"font-weight: 400;\">medical attention<\/span><span style=\"font-weight: 400;\"> in the event of any of these symptoms:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased or no ability to urinate<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Painful urination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling in the extremities, particularly the feet and ankles<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tiredness<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Sources<\/span><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=24731405-219c-79b4-ecf0-7d5fbfda94ba\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">IBU<\/span> <span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> tablets drug information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/online.epocrates.com\/drugs\/23301\/ibuprofen\/Adult-Dosing\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><\/a><span style=\"font-weight: 400;\">, Epocrates<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.pdr.net\/drug-summary\/Ibuprofen-Tablets-ibuprofen-2618\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Ibuprofen<\/span><\/a><span style=\"font-weight: 400;\">, Prescriber\u2019s Digital Reference<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=844c1047-9de5-4f47-b7cc-efb1928c21d8\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">IBU<\/span> <span style=\"font-weight: 400;\">ibuprofen<\/span><span style=\"font-weight: 400;\"> tablets prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Common ibuprofen side effects | Serious side effects | High blood pressure | Acute kidney injury | Stomach ulcers | Side effects timeline | Contraindications | Warnings | Interactions | How to avoid side effects | How to treat side effects Ibuprofen is a common over-the-counter pain reliever and fever reducer that is safe for [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":53161,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12752,808],"coauthors":[8861],"class_list":["post-53159","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-medication-side-effects","tag-pain-management","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Ibuprofen side effects and how to avoid them | SingleCare<\/title>\n<meta name=\"description\" content=\"High blood pressure, acute kidney injury, and stomach ulcers are common ibuprofen side effects. 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