{"id":53196,"date":"2022-08-23T08:43:33","date_gmt":"2022-08-23T12:43:33","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53196"},"modified":"2024-11-13T18:30:33","modified_gmt":"2024-11-13T23:30:33","slug":"risperidone-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/risperidone-side-effects\/","title":{"rendered":"Risperidone side effects and how to avoid them"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#common-risperidone-side-effects\">Common risperidone side effects<\/a>\u00a0| <a href=\"#serious-side-effects\">Serious side effects<\/a> | <a href=\"#weight-gain\">Weight gain<\/a> | <a href=\"#gynecomastia\">Gynecomastia<\/a> | <a href=\"#tardive-dyskinesia\">Tardive dyskinesia<\/a> | <a href=\"#sexual-dysfunction\">Sexual dysfunction<\/a> | <a href=\"#side-effects-timeline\">Side effects timeline<\/a> | <a href=\"#contraindications\">Contraindications<\/a> | <a href=\"#warnings\">Warnings<\/a> | <a href=\"#interactions\">Interactions<\/a> | <a href=\"#how-to-avoid-side-effects\">How to avoid side effects<\/a> | <a href=\"#how-to-treat-side-effects\">How to treat side effects<\/a><\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/risperidone\"><span style=\"font-weight: 400;\">Risperidone<\/span><\/a><span style=\"font-weight: 400;\"> is a generic prescription drug used to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/schizophrenia-treatment-and-medications\"><span style=\"font-weight: 400;\">schizophrenia<\/span><\/a><span style=\"font-weight: 400;\"> and manic episodes due to <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/bipolar-disorder-treatment-and-medications\"><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/a><span style=\"font-weight: 400;\">. The Food and Drug Administration (FDA) has also approved risperidone to treat irritability in children and adolescents with autism. Many people, however, are more familiar with risperidone\u2019s brand-name version, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/risperdal\"><span style=\"font-weight: 400;\">Risperdal<\/span><\/a><span style=\"font-weight: 400;\">. Risperidone belongs to a family of <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">antipsychotic medications<\/span><\/a><span style=\"font-weight: 400;\"> called <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/atypical-antipsychotics\"><span style=\"font-weight: 400;\">atypical antipsychotics<\/span><\/a><span style=\"font-weight: 400;\">. Antipsychotics work by blocking dopamine, a neurotransmitter that is responsible for many of the symptoms of schizophrenia and mania. Atypical antipsychotics, though, are less likely to cause some severe side effects than the first generation of antipsychotics. Risperidone does, however, have side effects, and many people taking the drug may experience one or more of them.<\/span><\/p>\n<h2 id=\"common-risperidone-side-effects\"><span style=\"font-weight: 400;\">Common side effects of risperidone<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most common side effect of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/risperidone\/what-is\"><span style=\"font-weight: 400;\">risperidone<\/span><\/a><span style=\"font-weight: 400;\"> is drowsiness, affecting as many as <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Risperidone-risperidone-3120.8240\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">3 in 5 people<\/span><\/a><span style=\"font-weight: 400;\"> taking the drug. Risperidone\u2019s <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/119805\/risperidone\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">most common side effects<\/span><\/a><span style=\"font-weight: 400;\"> are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drowsiness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Increased appetite<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Insomnia<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Parkinsonism (Parkinson\u2019s disease symptoms: tremor, slowness, muscle stiffness, difficulty balancing)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cough<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Anxiety<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Runny nose<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood sugar<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tremor<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Restlessness and compulsive movements<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated prolactin levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acid indigestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal congestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Excess salivation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Frequent nighttime urination<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinary incontinence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elevated fats and cholesterol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Involuntary muscle contractions or tightness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dry mouth<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Upper respiratory infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cold symptoms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Throat pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back or muscle pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breast development in men<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sensitivity to sunlight<\/span><\/li>\n<\/ul>\n<h2 id=\"serious-side-effects\"><span style=\"font-weight: 400;\">Serious side effects of risperidone<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most serious side effects of risperidone are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Extrapyramidal symptoms (drug-induced involuntary movements and muscle contractions)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High fat and cholesterol levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suicidal thoughts\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sudden drop in blood pressure when standing (orthostatic hypotension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fainting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chest pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Painful or prolonged erections (<\/span><a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/priapism\/symptoms-causes\/syc-20352005\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">priapism<\/span><\/a><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Body temperature dysregulation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart rate changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low white blood cell counts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Neuroleptic malignant syndrome (NMS)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions<\/span><\/li>\n<\/ul>\n<h3 id=\"weight-gain\"><span style=\"font-weight: 400;\">Weight gain<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Weight gain is a common problem with risperidone as it is with many atypical antipsychotics. As many as <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Risperidone-risperidone-3120.8240\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">1 in 3<\/span><\/a><span style=\"font-weight: 400;\"> patients report weight gain as a side effect. <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=e90c886c-132a-4df6-8604-cfe5ffa49d5b#LINK_c3230e9f-518f-4b29-b38e-9f0c412f7066\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">In controlled trials<\/span><\/a><span style=\"font-weight: 400;\">, people taking risperidone showed an average weight gain of nine pounds after six months and 11 pounds after 12 months of use\u00a0<\/span><\/p>\n<h3 id=\"gynecomastia\"><span style=\"font-weight: 400;\">Gynecomastia<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Risperidone can increase prolactin levels in the body, more than other antipsychotics. Hyperprolactinemia may have <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537331\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">several effects<\/span><\/a><span style=\"font-weight: 400;\"> on men, including impotence, erectile dysfunction, decreased sex drive, and breast development (gynecomastia). The exact incidence of gynecomastia due to risperidone is unknown, but it is a delayed side effect that requires weeks or months of treatment to manifest. Breast development is a cosmetic concern but not a health risk. Both sexes, however, are at risk for osteoporosis if prolactin levels stay high for a long time.<\/span><\/p>\n<h3 id=\"tardive-dyskinesia\"><span style=\"font-weight: 400;\">Tardive dyskinesia<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tardive dyskinesia and other involuntary muscle movements (called extrapyramidal symptoms or EPS) are a concern with antipsychotics. Consisting of one or more involuntary movements such as tongue rolling, grimacing, lip smacking, and body movements, tardive dyskinesia causes approximately <\/span><a href=\"https:\/\/www.janssenlabels.com\/package-insert\/product-monograph\/prescribing-information\/RISPERDAL-pi.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">3% of risperidone patients to quit the drug<\/span><\/a><span style=\"font-weight: 400;\">. The incidence, however, <\/span><a href=\"https:\/\/www.pdr.net\/drug-summary\/Risperidone-risperidone-3120.8240#3\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">could be as high as 5%<\/span><\/a><span style=\"font-weight: 400;\">. Tardive dyskinesia is typically associated with dosage and duration of treatment but can occur early. Once tardive dyskinesia is a problem, the only solution is to stop the drug. Some people may see improvement a few months after the drug is discontinued, but it could be a lifelong condition in others.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Mental Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h3 id=\"sexual-dysfunction\"><span style=\"font-weight: 400;\">Sexual dysfunction<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Because risperidone increases prolactin levels, men and women may see a decline in sex hormones. For women, this will affect libido, arousal, and vaginal dryness. For men, this may lead to decreased libido, impotence, and ejaculation problems. One large study determined <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3623530\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">the incidence<\/span><\/a><span style=\"font-weight: 400;\"> of decreased sexual interest to be 60% among both men and women taking risperidone for a year. Sexual dysfunction was reported by 46% of those patients, making risperidone the antipsychotic most likely to produce sexual dysfunction. If sexual function is a problem, healthcare providers will usually start by reducing the dose or switching to another antipsychotic. In some cases, they may prescribe other medications such as erectile dysfunction drugs to help resolve the problem.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Risperidone side effects in females vs. males<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">In general, there are no significant differences in side effects between men and women taking risperidone. Elderly women may be more at risk for tardive dyskinesia, and at <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7751687\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">least one study<\/span><\/a><span style=\"font-weight: 400;\"> showed a greater incidence of skin problems in women taking risperidone. That being said, risperidone can increase prolactin levels in the body. Although hyperprolactinemia is not more likely in one sex versus another, this one side effect causes different problems in men and women. Women will experience menstrual problems, vaginal dryness, arousal problems, and milky discharge from their breasts. Men with too much prolactin may experience impotence, ejaculation problems, fertility problems, and enlarged breasts.\u00a0<\/span><\/p>\n<h2 id=\"side-effects-timeline\"><span style=\"font-weight: 400;\">How soon do risperidone side effects start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Risperidone can start showing side effects after the first dose. It takes about one hour after taking a dose for the medicine to hit its peak levels. Many common side effects such as sleepiness and headache could appear during that time. Some side effects, particularly the most serious side effects, may require days, weeks, or months to become a problem.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How long do risperidone side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most people will experience some side effects when taking risperidone. Some will improve over time, but many side effects are related to the duration of treatment. The longer the medicine is taken, the more side effects it will have. However, most of the common side effects will improve when the medication is discontinued. Some, like neuroleptic malignant syndrome, may require treatment to get better. Unfortunately, many risperidone side effects may be long-term or lifelong conditions such as tardive dyskinesia and diabetes.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What are the long-term side effects of risperidone?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many of risperidone\u2019s side effects are due to long-term use. Involuntary muscle movements, weight gain, metabolic problems, heart problems, and osteoporosis are all problems that occur when the drug is taken continuously over months or years. Some of them may continue to be problems even after the drug is stopped.\u00a0<\/span><\/p>\n<h2 id=\"contraindications\"><span style=\"font-weight: 400;\">Risperidone contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Risperidone is contraindicated in people who are allergic to risperidone or a similar drug called <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/invega\"><span style=\"font-weight: 400;\">Invega<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paliperidone-er\"><span style=\"font-weight: 400;\">paliperidone<\/span><\/a><span style=\"font-weight: 400;\">).<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Pregnancy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Taken during the third trimester, risperidone may cause involuntary muscle movements or withdrawal in a newborn. There is no expected risk for birth defects or miscarriage, but healthcare professionals are advised to weigh the pros and cons when prescribing risperidone to pregnant women.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Breastfeeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Risperidone is present in breast milk. Though the risk to a nursing infant has not been studied, there have been reports of breastfed infants who are sleepy, jittery, or have involuntary muscle movements when the mother is on risperidone. If risperidone is used while breastfeeding, the baby should be monitored for problems.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Risperidone is used cautiously in older adults and elderly patients because of the increased risk of falls, injuries, and heart problems. Because of potential hazards, risperidone is not used to treat psychosis in people with dementia. Healthcare providers usually start seniors at a low dose and regularly monitor them for blood pressure, heart problems, and other critical indicators during therapy.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Risperidone is approved for use in adolescents with bipolar disorder and children and adolescents with autism. However, children are vulnerable to experiencing aggression and suicidal thoughts, so their behavior will have to be monitored. Excess weight gain is also a risk, so body weight will have to be monitored.<\/span><\/p>\n<h2 id=\"warnings\"><span style=\"font-weight: 400;\">Risperidone warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">All antipsychotics have risks, so there are a few cautions in using risperidone.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Black box warning<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Risperidone\u2019s drug information includes a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\"> that risperidone increases the risk of death when given to elderly patients with dementia.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Cautions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Certain medical conditions might be worsened by risperidone, or they may increase the likelihood and severity of side effects. These include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low sodium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Parkinson\u2019s or similar neurological disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cardiovascular diseases such as heart attack, heart failure, or heart rhythm problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cerebrovascular diseases such as stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure, low blood volume, or dehydration<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A history of blood problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Problems with swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Phenylketonuria (for people taking orally disintegrating tablets)<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">Body temperature\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Antipsychotics like risperidone interfere with the body\u2019s ability to regulate its internal temperature, so people taking the drug are at risk of both hyperthermia and hypothermia, but hyperthermia is the more likely hazard. People taking risperidone should be cautious about hot and cold ambient temperatures and avoid strenuous exercise.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Risperidone is not considered a drug likely to be abused or to cause physical dependence. It may, however, cause withdrawal when abruptly discontinued. The prescribing healthcare provider will use a steadily decreasing dose when the drug needs to be stopped.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Get medical help or call a poison helpline when too much risperidone has been taken. An overdose will primarily amplify risperidone\u2019s side effects such as drowsiness, sleepiness, low blood pressure, racing heartbeats, and involuntary movements such as twitching.<\/span><\/p>\n<h2 id=\"interactions\"><span style=\"font-weight: 400;\">Risperidone interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some of risperidone\u2019s problems are due to drug interactions, so healthcare providers and patients should be cautious about combining risperidone with:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Other antipsychotic drugs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Central nervous system depressants such as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/sleep-aids-guide\/\"><span style=\"font-weight: 400;\">sedatives<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/barbiturates\/\"><span style=\"font-weight: 400;\">barbiturates<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/anxiolytics\/\"><span style=\"font-weight: 400;\">anxiety medications<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/opioids\/\"><span style=\"font-weight: 400;\">opioids<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/muscle-relaxants\/\"><span style=\"font-weight: 400;\">muscle relaxants<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/benzodiazepines\/\"><span style=\"font-weight: 400;\">benzodiazepines<\/span><\/a><span style=\"font-weight: 400;\">, marijuana, and alcohol<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood pressure medications<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs that block the ability of the body to break down risperidone such as selective serotonin reuptake inhibitors (<\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">SSRIs<\/span><\/a><span style=\"font-weight: 400;\"> like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/paroxetine-hcl\"><span style=\"font-weight: 400;\">paroxetine<\/span><\/a><span style=\"font-weight: 400;\">) and azole <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antifungals\"><span style=\"font-weight: 400;\">antifungal<\/span><\/a><span style=\"font-weight: 400;\"> drugs<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs that speed up the body\u2019s metabolism of risperidone and decrease its effectiveness such as <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/h2-antagonists\"><span style=\"font-weight: 400;\">H2 blockers<\/span><\/a><span style=\"font-weight: 400;\"> and some anticonvulsants like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/carbamazepine\"><span style=\"font-weight: 400;\">carbamazepine<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/phenytoin-sodium\"><span style=\"font-weight: 400;\">phenytoin<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-avoid-side-effects\"><span style=\"font-weight: 400;\">How to avoid risperidone side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Unfortunately, most people will encounter one or more side effects when taking risperidone. Some are avoidable, but many others can be minimized by following a few simple rules.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">1. Give the healthcare provider a complete medical history<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The surest way to prevent some of the most serious side effects of risperidone is to give the prescriber a complete medical history, including family history, personal history, and all prescription drugs, over-the-counter drugs, and dietary supplements being taken. Some are more important than others such as:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes or a family history of diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Heart problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stroke<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low white blood cell counts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Low sodium<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Problems with swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy or pregnancy plans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breastfeeding or plans to breastfeed<\/span><\/li>\n<\/ul>\n<h3><span style=\"font-weight: 400;\">2. Take risperidone as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Follow the instructions given by the prescriber or written on the prescription label. Do not take more or less of the medicine. If a dose of risperidone is missed, take it when remembered. However, if it\u2019s almost time for the next dose, skip the missed dose and take the next dose as scheduled.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">3. Keep all appointments<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The prescribing healthcare provider will monitor for potentially serious side effects and may perform blood tests, ECGs, or other tests. Keep these appointments and always tell the prescriber about any problems.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">4. Eat a healthy diet<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Eating a healthy diet can help prevent or minimize weight gain. A low-fat and reduced carbohydrate diet could help stave off some of the metabolic adverse effects such as diabetes, high cholesterol, or high triglycerides. Ask the prescriber or a nutritionist for a recommended diet.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">5. Don\u2019t drink alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Combining risperidone with alcohol, marijuana, sleeping pills, or other sleep-inducing drugs will amplify risperidone side effects such as drowsiness, lightheadedness, and dizziness. All of these raise the risk of falls, injuries, and accidents.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">6. Be cautious about driving and other risky activities<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Many of risperidone\u2019s side effects raise the risk of potentially life-threatening accidents or injuries when driving, operating machinery, engaging in sports, or other risky activities. Try to avoid these activities until the effects of the drug on alertness and judgment are fully understood.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects\"><span style=\"font-weight: 400;\">How to treat side effects of risperidone<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Because risperidone is so likely to cause side effects, most people will need to learn how to manage them. Here are some tips.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Drowsiness and dizziness<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">When sleepiness or dizziness attacks, sit down and stay seated until the problem passes. Stay seated until the attack passes.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Fainting and lightheadedness<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some people taking risperidone may feel like they\u2019re going to black out whenever they stand up. Again, the best solution is to sit down and stay seated until lightheadedness passes. Then stand up slowly and move slowly to prevent it from happening again.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Dry mouth<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Chewing sugarless gum, sucking on sugarless candy, or just sipping water can help. If the problem is too hard to live with, ask the prescribing healthcare provider for medical advice.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Sexual dysfunction<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If risperidone is causing problems with sex, talk to the prescribing healthcare provider. There may be options like reducing the dose or switching to another antipsychotic.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Common risperidone side effects\u00a0| Serious side effects | Weight gain | Gynecomastia | Tardive dyskinesia | Sexual dysfunction | Side effects timeline | Contraindications | Warnings | Interactions | How to avoid side effects | How to treat side effects Risperidone is a generic prescription drug used to treat schizophrenia and manic episodes due to [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":53207,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[12752,450],"coauthors":[8861],"class_list":["post-53196","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-medication-side-effects","tag-mental-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Risperidone side effects and how to avoid them | SingleCare<\/title>\n<meta name=\"description\" content=\"Weight gain, gynecomastia, and sexual dysfunction are common risperidone side effects. 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