{"id":53209,"date":"2022-08-16T15:22:25","date_gmt":"2022-08-16T19:22:25","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53209"},"modified":"2022-08-16T16:43:06","modified_gmt":"2022-08-16T20:43:06","slug":"nuedexta-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/nuedexta-alternatives\/","title":{"rendered":"Nuedexta alternatives: What can I take instead of Nuedexta?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#compare-nuedexta-alternatives\"> Compare Nuedexta alternatives<\/a> | <a href=\"#tricyclic-antidepressants\">Tricyclic antidepressants<\/a> | <a href=\"#selective-serotonin-reuptake-inhibitors\">Selective serotonin reuptake inhibitors<\/a> | <a href=\"#other-antidepressants\">Other antidepressants<\/a> | <a href=\"#dopaminergic-agents\">Dopaminergic agents<\/a> | <a href=\"#lamictal\">Lamictal<\/a> | <a href=\"#natural-alternatives\">Natural alternatives<\/a> | <a href=\"#how-to-switch-meds\">How to switch meds<\/a><\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/nuedexta\/what-is\"><span style=\"font-weight: 400;\">Nuedexta<\/span><\/a><span style=\"font-weight: 400;\"> is a prescription drug used to treat pseudobulbar affect (PBA) in adults. PBA is a neurological condition that can cause uncontrollable laughing or crying episodes. Certain conditions, such as <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/alzheimers-treatment-and-medications\"><span style=\"font-weight: 400;\">Alzheimer\u2019s disease<\/span><\/a><span style=\"font-weight: 400;\">, multiple sclerosis, and Parkinson\u2019s disease, are often linked to the development of PBA.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Nuedexta is a brand-name drug that contains a combination of dextromethorphan hydrobromide and quinidine sulfate. Dextromethorphan is commonly used as an antitussive or cough suppressant, while quinidine is classified as an antiarrhythmic drug. Although the exact way in which it works is unknown, Nuedexta is the only FDA-approved drug used to reduce PBA episodes.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Nuedexta is an effective drug for PBA but is only available as a brand-name drug. Without a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/are-generic-drugs-as-good-as-brand-name-medicines\/\"><span style=\"font-weight: 400;\">generic version<\/span><\/a><span style=\"font-weight: 400;\">, Nuedexta can be expensive. Some people may also have trouble swallowing Nuedexta capsules or experience intolerable side effects from the drug. For these reasons, some healthcare providers and patients may be looking for a Nuedexta alternative.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Continue reading to learn more about Nuedexta alternatives.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What can I take in place of Nuedexta?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some people might think they can take the active ingredients of Nuedexta separately. Delsym (dextromethorphan polistirex) is an available drug that contains dextromethorphan. However, Delsym contains dextromethorphan surrounded by an edible plastic called polistirex. The dextromethorphan in Delsym is quickly converted to dextrorphan, a metabolite of dextromethorphan that has <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antitussives\"><span style=\"font-weight: 400;\">antitussive effects<\/span><\/a><span style=\"font-weight: 400;\"> and is not as effective for PBA as the dextromethorphan in Nuedexta. Quinidine is available as a separate oral tablet; however, quinidine tablets are only available in 200 mg or 300 mg strength, which is higher than the 10 mg strength of quinidine in Nuedexta.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are no other FDA-approved drugs to treat PBA. However, some drugs may be prescribed for <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label use<\/span><\/a><span style=\"font-weight: 400;\"> in which a healthcare provider can prescribe a drug for an unapproved condition.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3849173\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Alternative Nuedexta treatment options<\/span><\/a><span style=\"font-weight: 400;\"> include<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/tricyclic-antidepressants\/\"><span style=\"font-weight: 400;\"> tricyclic antidepressants<\/span><\/a><span style=\"font-weight: 400;\">, such as Elavil (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/amitriptyline-hcl\"><span style=\"font-weight: 400;\">amitriptyline<\/span><\/a><span style=\"font-weight: 400;\">) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/pamelor\/what-is\"><span style=\"font-weight: 400;\">Pamelor<\/span><\/a><span style=\"font-weight: 400;\"> (nortriptyline), and selective serotonin reuptake inhibitors (SSRIs), such as <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/celexa\/what-is\"><span style=\"font-weight: 400;\">Celexa<\/span><\/a><span style=\"font-weight: 400;\"> (citalopram), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\/what-is\"><span style=\"font-weight: 400;\">Zoloft<\/span><\/a><span style=\"font-weight: 400;\"> (sertraline), and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/prozac\/what-is\"><span style=\"font-weight: 400;\">Prozac<\/span><\/a><span style=\"font-weight: 400;\"> (fluoxetine). Antidepressants used to treat PBA are often prescribed at a lower dose than they normally would be prescribed for depression. They may have different costs, side effects, formulations, and dosages from Nuedexta. <\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"compare-nuedexta-alternatives\"><span class=\"title\">Compare Nuedexta alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage (for PBA)<\/b><\/td>\n<td><b>Coupons<\/b><\/td>\n<\/tr>\n<tr>\n<td>Nuedexta (dextromethorphan\/quinidine)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Pseudobulbar affect (PBA)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">20 mg\/10 mg daily for 7 days, and then 20 mg\/10 mg every 12 hours<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/nuedexta\">Nuedexta coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Elavil<\/p>\n<p>(amitriptyline)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Depression<\/li>\n<li aria-level=\"1\">Pseudobulbar affect (PBA) (off-label use)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">10 to 75 mg daily<\/li>\n<li aria-level=\"1\">Dosage may vary depending on the treated condition, the response to treatment, and other factors<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/amitriptyline-hcl\">Amitriptyline coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Pamelor<\/p>\n<p>(nortriptyline)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Depression<\/li>\n<li aria-level=\"1\">Pseudobulbar affect (PBA) (off-label use)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">10 to 25 mg daily<\/li>\n<li aria-level=\"1\">Dosage may vary depending on the treated condition, the response to treatment, and other factors<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/pamelor\">Pamelor coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Celexa<\/p>\n<p>(citalopram)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Depression<\/li>\n<li aria-level=\"1\">Pseudobulbar affect (PBA) (off-label use)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">5 to 40 mg daily<\/li>\n<li aria-level=\"1\">Dosage may vary depending on the treated condition, the response to treatment, and other factors<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/celexa\">Celexa coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Zoloft<\/p>\n<p>(sertraline)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Depression<\/li>\n<li aria-level=\"1\">Obsessive compulsive disorder (OCD)<\/li>\n<li aria-level=\"1\">Panic disorder<\/li>\n<li aria-level=\"1\">Post-traumatic stress disorder (PTSD)<\/li>\n<li aria-level=\"1\">Social anxiety disorder (SAD)<\/li>\n<li aria-level=\"1\">Premenstrual dysphoric disorder (PMDD)<\/li>\n<li aria-level=\"1\">Pseudobulbar affect (PBA) (off-label use)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">50 to 100 mg daily<\/li>\n<li aria-level=\"1\">Dosage may vary depending on the treated condition, the response to treatment, and other factors<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zoloft\">Zoloft coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Prozac<\/p>\n<p>(fluoxetine<\/p>\n<p>)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Depression<\/li>\n<li aria-level=\"1\">Obsessive compulsive disorder (OCD)<\/li>\n<li aria-level=\"1\">Bulimia nervosa<\/li>\n<li aria-level=\"1\">Depressive episodes of bipolar disorder<\/li>\n<li aria-level=\"1\">Pseudobulbar affect (PBA) (off-label use)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">20 mg daily<\/li>\n<li aria-level=\"1\">Dosage may vary depending on the treated condition, the response to treatment, and other factors<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/prozac\">Prozac coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Lexapro<\/p>\n<p>(escitalopram)<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">Depression<\/li>\n<li aria-level=\"1\">Generalized anxiety disorder (GAD)<\/li>\n<li aria-level=\"1\">Pseudobulbar affect (PBA) (off-label use)<\/li>\n<\/ul>\n<\/td>\n<td>\n<ul>\n<li aria-level=\"1\">5 to 20 mg daily<\/li>\n<li aria-level=\"1\">Dosage may vary depending on the treated condition, the response to treatment, and other factors<\/li>\n<\/ul>\n<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lexapro\">Lexapro coupons<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400;\">Other alternatives to Nuedexta<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tofranil (imipramine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gocovri (amantadine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sinemet (carbidopa\/levodopa)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lamictal (lamotrigine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Remeron (mirtazapine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Edronax (reboxetine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Effexor (venlafaxine)<\/span><\/li>\n<\/ul>\n<h2><span style=\"font-weight: 400;\">Top 5 Nuedexta alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most common alternatives to Nuedexta.<\/span><\/p>\n<h3 id=\"tricyclic-antidepressants\"><span style=\"font-weight: 400;\">1. Tricyclic antidepressants (TCAs) such as Elavil (amitriptyline), Pamelor (nortriptyline), and Tofranil (imipramine)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tricyclic antidepressants (TCAs) act on different neurotransmitters in the <\/span><a href=\"https:\/\/www.ajmc.com\/view\/pharmacotherapeutic-management-of-pseudobulbar-affect\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">central nervous system (CNS)<\/span><\/a><span style=\"font-weight: 400;\">. They mainly work by increasing serotonin and norepinephrine levels and blocking the action of acetylcholine. These drugs are approved to treat symptoms of depression. However, they may be prescribed off-label at lower doses for PBA. Some people may prefer to take a TCA due to the availability of low-cost, generic versions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although lower doses of TCAs may cause fewer side effects than high doses used for depression, side effects can still occur. Side effects of TCAs include dry mouth, constipation, blurred vision, and urinary retention.\u00a0<\/span><\/p>\n<h3 id=\"selective-serotonin-reuptake-inhibitors\"><span style=\"font-weight: 400;\">2. Selective serotonin reuptake inhibitors (SSRIs) such as Celexa (citalopram), Prozac (fluoxetine), and Zoloft (sertraline)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/drug-classes\/ssris\"><span style=\"font-weight: 400;\">Selective serotonin reuptake inhibitors (SSRIs)<\/span><\/a><span style=\"font-weight: 400;\"> work by increasing levels of serotonin in the brain. They\u2019re FDA approved to treat major depressive disorder, although some may also treat other mental health conditions, such as anxiety or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/ocd-treatment-and-medications\"><span style=\"font-weight: 400;\">OCD<\/span><\/a><span style=\"font-weight: 400;\">. A healthcare provider may prescribe an SSRI at low doses to reduce the frequency and severity of PBA episodes. SSRIs are widely available in brand and generic versions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">SSRIs generally have less severe side effects than older antidepressants, such as TCAs. Common side effects may include headache, dry mouth, insomnia, and sexual dysfunction.\u00a0<\/span><\/p>\n<h3 id=\"other-antidepressants\"><span style=\"font-weight: 400;\">3. Other antidepressants such as Remeron (mirtazapine) and Effexor (venlafaxine)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Other antidepressants may be prescribed off-label to treat PBA, including Remeron (mirtazapine) and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/effexor-xr\"><span style=\"font-weight: 400;\">Effexor<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/venlafaxine-hcl\"><span style=\"font-weight: 400;\">venlafaxine<\/span><\/a><span style=\"font-weight: 400;\">). Mirtazapine is an atypical antidepressant that helps balance norepinephrine and serotonin levels in the brain. Venlafaxine is a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/snris\"><span style=\"font-weight: 400;\">serotonin and norepinephrine reuptake inhibitor (SNRI)<\/span><\/a><span style=\"font-weight: 400;\"> that also helps balance norepinephrine and serotonin levels. These antidepressants are approved to treat depression but may be used off-label for PBA. Drowsiness and other CNS side effects are possible with many antidepressants.\u00a0<\/span><\/p>\n<h3 id=\"dopaminergic-agents\"><span style=\"font-weight: 400;\">4. Dopaminergic agents such as Senemet (carbidopa\/levodopa) and Gocovri (amantadine)\u00a0<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Dopaminergic agents have had lower response rates in people with PBA, but they may still be viable Nuedexta alternatives in some people. Glutamate is a neurotransmitter that binds to NMDA receptors and is believed to play a role in the development of emotional affect. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/amantadine-hcl\"><span style=\"font-weight: 400;\">Amantadine<\/span><\/a><span style=\"font-weight: 400;\"> is an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/nmda-receptor-antagonists\"><span style=\"font-weight: 400;\">NMDA receptor antagonist<\/span><\/a><span style=\"font-weight: 400;\"> that reduces the activity of glutamate. Carbidopa and levodopa influence dopamine activity in the brain. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/6477219\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Small-scale clinical trials<\/span><\/a><span style=\"font-weight: 400;\"> have shown that these dopaminergic agents may be effective in decreasing PBA episodes.\u00a0<\/span><\/p>\n<h3 id=\"lamictal\"><span style=\"font-weight: 400;\">5. Lamictal (lamotrigine)<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/lamictal\"><span style=\"font-weight: 400;\">Lamictal<\/span><\/a><span style=\"font-weight: 400;\"> is a brand-name drug also known by its generic name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lamotrigine\"><span style=\"font-weight: 400;\">lamotrigine<\/span><\/a><span style=\"font-weight: 400;\">. It works as an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticonvulsants\"><span style=\"font-weight: 400;\">anticonvulsant<\/span><\/a><span style=\"font-weight: 400;\"> that reduces the actions of glutamate and aspartate, which are excitatory neurotransmitters. Lamictal is available as a generic drug. Side effects may include headaches, drowsiness, and dizziness.\u00a0<\/span><\/p>\n<h2 id=\"natural-alternatives\"><span style=\"font-weight: 400;\">Natural alternatives to Nuedexta<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are no approved natural remedies or supplements that can treat PBA. However, your healthcare provider may recommend coping strategies in addition to a prescription medication. A combination of medications and coping strategies may help make PBA easier to live with.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Relaxation methods<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Relaxation methods, such as yoga, meditation, and deep breathing, may help alleviate a PBA episode. Yoga involves relaxing the body through a number of slow and controlled movements. Meditation can involve different practices, such as focusing on the breath or getting more in touch with the body. Practicing slow, deep breathing can also help calm the mind and body during an episode.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Distraction<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Focusing on something else can help distract the mind during an episode. Working on a puzzle, journaling what\u2019s happening in the environment, visualizing a specific memory, or counting backward from 100 can also help keep the mind busy enough to stop an episode in its tracks.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Moving away from the cause<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Sometimes the best way to handle an episode is to remove yourself from the situation causing the episode. Take a break by going to a different room or walking outside. During severe episodes, removing yourself can be difficult. However, it\u2019s still an option.\u00a0<\/span><\/p>\n<h2 id=\"how-to-switch-meds\"><span style=\"font-weight: 400;\">How to switch to a Nuedexta alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">It can take time for Nuedexta to work. A healthcare provider may recommend waiting up to <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2019\/021879s014lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">around 90 days<\/span><\/a><span style=\"font-weight: 400;\"> for Nuedexta to start providing maximum benefits. Nuedexta may not work the same for everyone. If Nuedexta hasn\u2019t reduced or improved PBA episodes or has caused unwanted side effects, it may be a good time to talk to a healthcare provider about switching medications.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Switching to a Nuedexta alternative<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Switching to a Nuedexta alternative will depend on <\/span><a href=\"https:\/\/www.nationalmssociety.org\/NationalMSSociety\/media\/MSNationalFiles\/Brochures\/Clinical-Bulletin-Pseudobulbar.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">different factors<\/span><\/a><span style=\"font-weight: 400;\">, such as how long the current treatment with Nuedexta has been, side effects experienced from the drug, and the medication Nuedexta is being switched to. Nuedexta is not known to cause withdrawal symptoms that are common with other medications used for mental health conditions, such as antidepressants and antipsychotics. The only cases of withdrawal from dextromethorphan have been reported with the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/cough-syrup-addiction-abuse\/\"><span style=\"font-weight: 400;\">abuse or misuse of dextromethorphan syrup<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In many cases, Nuedexta can be discontinued immediately, and another drug can be started. However, the process for switching medications will be facilitated by the prescribing healthcare provider. To prevent adverse effects, a healthcare provider may recommend tapering or gradually lowering the dose of Nuedexta over time.\u00a0<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Switching between Nuedexta alternatives<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Switching between Nuedexta alternatives can also involve different processes. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/switching-antidepressants\/\"><span style=\"font-weight: 400;\">Switching between different antidepressants<\/span><\/a><span style=\"font-weight: 400;\"> may involve tapering the dose of the original drug or discontinuing the drug and directly switching to a different medication.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The treatment of pseudobulbar affect is possible through various medications. The best treatment option for you can vary based on the cost of the drug, current medical conditions, and potential side effects and drug interactions. Always discuss with a healthcare provider your current health condition and other drugs you\u2019re taking, including prescription drugs, over-the-counter medicine, and herbal supplements, before taking a new medication.\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Compare Nuedexta alternatives | Tricyclic antidepressants | Selective serotonin reuptake inhibitors | Other antidepressants | Dopaminergic agents | Lamictal | Natural alternatives | How to switch meds Nuedexta is a prescription drug used to treat pseudobulbar affect (PBA) in adults. PBA is a neurological condition that can cause uncontrollable laughing or crying episodes. Certain conditions, [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":53212,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[15103,4350],"coauthors":[8669],"class_list":["post-53209","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-pricing","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top Nuedexta alternatives and how to switch your Rx | SingleCare<\/title>\n<meta name=\"description\" content=\"Tricyclic antidepressants, SSRIs, dopaminergic agents, and Lamictal are some Nuedexta alternatives. Get the full list here.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/nuedexta-alternatives\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Nuedexta alternatives: What can I take instead of Nuedexta?\" \/>\n<meta property=\"og:description\" content=\"Tricyclic antidepressants, SSRIs, dopaminergic agents, and Lamictal are some Nuedexta alternatives. 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