{"id":53499,"date":"2022-09-13T10:12:42","date_gmt":"2022-09-13T14:12:42","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53499"},"modified":"2025-08-14T18:03:11","modified_gmt":"2025-08-14T22:03:11","slug":"clonazepam-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/clonazepam-alternatives\/","title":{"rendered":"5 clonazepam alternatives and how to switch your Rx"},"content":{"rendered":"

Clonazepam<\/span><\/a> (<\/span>brand name<\/span> Klonopin<\/span>) is a common medication used to help treat <\/span>panic attacks<\/span> and certain types of seizure disorders. <\/span>Clonazepam<\/span> belongs to the class of medications called <\/span>benzodiazepines<\/span>. <\/span>Benzodiazepines<\/span><\/a> work by increasing the effectiveness of the <\/span>neurotransmitter<\/span> gamma-aminobutyric acid<\/span> (<\/span>GABA<\/span>), a chemical messenger in the brain, which controls the excitability of neurons. These medications decrease the excitability of neurons, leading to a calming effect on the central nervous system. <\/span>Clonazepam<\/span> is also used <\/span>off-label<\/span><\/a> (for a non-<\/span>FDA<\/span>-approved use) to treat other conditions such as <\/span>anxiety<\/span><\/a>, <\/span>restless legs syndrome<\/span><\/a>, and <\/span>insomnia<\/span><\/a>. <\/span>Clonazepam<\/span><\/a> is available as an oral tablet and an oral disintegrating tablet, which can be useful for people who have difficulty swallowing pills.\u00a0<\/span><\/p>\n

Potential drawbacks of clonazepam<\/span><\/h2>\n

While an effective treatment for some people, <\/span>clonazepam<\/span> may not be the best and safest option for everyone. <\/span>Benzodiazepines<\/span>, like <\/span>clonazepam<\/span>, have serious risks if used with <\/span>opioids<\/span><\/a>, which may lead to extreme <\/span>sedation<\/span>, respiratory depression, coma, and death. Because of these risks, the use of <\/span>benzodiazepines<\/span> and <\/span>opioids<\/span> together should be avoided\u2014or carefully monitored, if they must be used together. Additionally, <\/span>benzodiazepines<\/span> can be <\/span>habit-forming<\/span> and carry risks of abuse, misuse, and addiction. Abuse and misuse of <\/span>benzodiazepines<\/span> (sometimes referred to as <\/span>benzos<\/span>) can often involve the use of doses greater than the maximum recommended dosage and commonly involve the use of other medications, alcohol, or illicit substances. Abuse and misuse are associated with an increased frequency of serious adverse outcomes, including respiratory depression, overdose, or death. As a result, <\/span>benzodiazepines<\/span> are classified as <\/span>controlled medications<\/span><\/a>, specifically as Schedule IV by the DEA (Drug Enforcement Administration).<\/span><\/p>\n

RELATED: <\/b>Preventing teen prescription misuse<\/b><\/a><\/p>\n

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Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t

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What can I take in place of <\/span>clonazepam<\/span>?<\/span><\/h2>\n

There are other options available to treat <\/span>panic attacks<\/span> and related anxiety conditions that do not improve with <\/span>clonazepam<\/span>. When considering alternative <\/span>prescription medication<\/span>, it\u2019s important to consider the specific condition being treated and the potential for abuse, which may include a history of drug misuse or abuse, alcohol dependence, or a history of placement in treatment programs. For panic disorder or other related anxiety conditions, there are several classes of medications that could be used as alternatives, including other <\/span>benzodiazepines<\/span>, selective serotonin reuptake <\/span>inhibitors<\/span> (<\/span>SSRIs<\/span><\/a>), or serotonin-norepinephrine reuptake <\/span>inhibitors<\/span> (<\/span>SNRIs<\/span><\/a>). These <\/span>treatment options<\/span> may be more suitable for certain individuals.<\/span><\/p>\n

RELATED: <\/b>Clonazepam<\/b> side effects<\/b> and how to avoid them<\/b><\/a><\/p>\n

Top 5 <\/span>clonazepam<\/span> alternatives<\/span><\/h2>\n

The following are some of the most common alternatives to <\/span>clonazepam<\/span>.<\/span><\/p>\n

2. <\/span>Valium<\/span> (<\/span>diazepam<\/span>)<\/span><\/h3>\n

RELATED: <\/b>Klonopin<\/b> vs. <\/b>Valium<\/b>: Differences, similarities, and which is better for you<\/b><\/a><\/p>\n

3. Prozac (fluoxetine)\u00a0<\/span><\/h3>\n

Antidepressants are often a <\/span>first-choice treatment<\/span><\/a> not only for depression, but also for anxiety. <\/span>Fluoxetine<\/span><\/a> is a selective serotonin reuptake <\/span>inhibitor<\/span> (<\/span>SSRI<\/span>) that is used to manage major depressive disorder (<\/span>depression<\/span><\/a>), <\/span>obsessive-compulsive disorder<\/span><\/a> (OCD), <\/span>panic disorder<\/span>, and <\/span>bulimia nervosa<\/span><\/a>. Unlike <\/span>benzodiazepines<\/span>, <\/span>SSRIs<\/span> are not associated with tolerance or <\/span>physical dependence<\/span>. <\/span>Side effects<\/span> of fluoxetine include anxiety, agitation, insomnia, tremors, nausea, anorexia, headache, and sexual problems. It\u2019s important for new users of <\/span>SSRIs<\/span> to know it may take up to <\/span>six weeks<\/span><\/a> for the medication to reach its full effects, versus the faster response seen with <\/span>benzodiazepines<\/span>. Fluoxetine is available in several <\/span>dosage<\/span><\/a> strengths as tablets, capsules, delayed-release capsules, and liquid.<\/span><\/p>\n

4. Paxil (paroxetine)\u00a0<\/span><\/h3>\n

Paroxetine<\/span><\/a> is an <\/span>SSRI<\/span> that is used to manage conditions such as generalized <\/span>anxiety disorder<\/span>, depression, OCD, <\/span>panic disorder<\/span>, and social <\/span>anxiety disorder<\/span>. Unlike <\/span>benzodiazepines<\/span>, <\/span>SSRIs<\/span> are not associated with tolerance or <\/span>physical dependence<\/span>. <\/span>Common side effects<\/span> of paroxetine include nausea, weakness, insomnia, dizziness, <\/span>sleepiness<\/span>, diarrhea or constipation, dry mouth, and yawning. As with Prozac, it may take several weeks for paroxetine to reach its full effects. Paroxetine is available as capsules, tablets, extended-release tablets, and liquid.<\/span><\/p>\n

5. Effexor XR (venlafaxine extended-release)\u00a0<\/span><\/h3>\n

Venlafaxine extended-release<\/span><\/a> (ER) is a serotonin-norepinephrine reuptake <\/span>inhibitor<\/span> (SNRI) that is used to manage generalized <\/span>anxiety disorder<\/span>, depression, <\/span>panic disorder<\/span>, and social <\/span>anxiety disorder<\/span>. Unlike <\/span>benzodiazepines<\/span>, SNRIs are not associated with tolerance or <\/span>physical dependence<\/span>. <\/span>Common side effects<\/span> of venlafaxine ER include nausea, <\/span>sleepiness<\/span>, dry mouth, sweating, sexual problems, appetite loss, and constipation. As an antidepressant, it may take several weeks to reach its full effects. Venlafaxine ER is available in capsule form and is typically taken once daily.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Compare clonazepam alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nDrug class<\/b><\/td>\nUses<\/b><\/td>\nCoupons<\/b><\/td>\n<\/tr>\n
Klonopin<\/strong><\/p>\n

(clonazepam)<\/strong><\/td>\n

Benzodiazepine\u00a0<\/span><\/td>\n–<\/span>Panic disorder<\/span><\/p>\n

-Seizure disorder<\/span><\/td>\n

Klonopin<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Xanax<\/strong><\/p>\n

(alprazolam<\/strong>)<\/strong>\u00a0<\/span><\/td>\n

Benzodiazepine<\/span><\/td>\n-Generalized <\/span>anxiety disorder<\/span><\/p>\n

–<\/span>Panic disorder<\/span><\/td>\n

Xanax<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Valium<\/strong><\/p>\n

(diazepam)\u00a0<\/strong><\/td>\n

Benzodiazepine<\/span><\/td>\n-Alcohol withdrawal<\/span><\/p>\n

–<\/span>Anxiety disorder<\/span><\/p>\n

-Muscle spasm<\/span><\/p>\n

-Procedural <\/span>sedation<\/span><\/p>\n

-Seizure disorder<\/span><\/td>\n

Valium coupons<\/span><\/a>\u00a0<\/span><\/td>\n<\/tr>\n
Prozac<\/strong><\/p>\n

(fluoxetine)<\/strong>\u00a0<\/span><\/td>\n

SSRI\u00a0<\/span><\/td>\n-Major depressive disorder<\/span><\/p>\n

-Obsessive-compulsive disorder\u00a0<\/span><\/p>\n

–<\/span>Panic disorder<\/span><\/p>\n

-Bulimia nervosa<\/span><\/td>\n

Prozac coupons<\/span><\/a><\/td>\n<\/tr>\n
Ativan<\/strong><\/p>\n

(lorazepam<\/strong>)<\/strong>\u00a0<\/span><\/td>\n

Benzodiazepine<\/span><\/td>\n–<\/span>Anxiety disorder<\/span><\/p>\n

-Insomnia<\/span><\/p>\n

-Status epilepticus<\/span><\/td>\n

Ativan<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Paxil<\/strong><\/p>\n

(paroxetine)<\/strong>\u00a0<\/span><\/td>\n

SSRI<\/span><\/td>\n-Generalized <\/span>anxiety disorder<\/span><\/p>\n

-Major depressive disorder<\/span><\/p>\n

-Obsessive-compulsive disorder<\/span><\/p>\n

–<\/span>Panic disorder<\/span><\/p>\n

-Social <\/span>anxiety disorder<\/span><\/td>\n

Paxil coupons<\/span><\/a><\/td>\n<\/tr>\n
Zoloft<\/strong><\/p>\n

(sertraline)\u00a0<\/strong><\/td>\n

SSRI<\/span><\/td>\n-Major depressive disorder<\/span><\/p>\n

-Obsessive-compulsive disorder<\/span><\/p>\n

–<\/span>Panic disorder<\/span><\/p>\n

-Post-traumatic stress disorder<\/span><\/p>\n

-Premenstrual dysphoric disorder<\/span><\/p>\n

-Social <\/span>anxiety disorder<\/span><\/td>\n

Zoloft coupons<\/span><\/a><\/td>\n<\/tr>\n
Effexor XR<\/strong><\/p>\n

(venlafaxine extended release)<\/strong>\u00a0<\/span><\/td>\n

SNRI<\/span><\/td>\n-Generalized <\/span>anxiety disorder<\/span><\/p>\n

-Major depressive disorder<\/span><\/p>\n

–<\/span>Panic disorder<\/span><\/p>\n

-Social <\/span>anxiety disorder<\/span><\/td>\n

Effexor XR coupons<\/span><\/a><\/td>\n<\/tr>\n
Buspirone\u00a0<\/strong><\/td>\nAnxiolytic\u00a0<\/span><\/td>\n-Generalized anxiety disorder<\/span><\/td>\nBuspirone coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Some of the medications listed may also be used for seizures, but this article focuses on their use for anxiety and panic disorder.<\/span><\/i><\/h5>\n

Natural alternatives to <\/span>clonazepam<\/span><\/h2>\n

Alternative remedies for <\/span>clonazepam<\/span> include therapy, lifestyle changes, and diet modifications to help improve mood and overall well-being. Some of these remedies include regular exercise, cognitive behavioral therapy, and avoiding triggers.<\/span><\/p>\n

Both high-intensity exercise and consistent low-intensity exercise can have a <\/span>positive impact on brain function<\/span><\/a>, improving how people feel. High-intensity exercise releases the body’s feel-good chemicals called endorphins, while low-intensity exercise promotes the release of proteins that cause nerve cells to grow and make new connections.<\/span><\/p>\n

RELATED: <\/b>7 health conditions that exercise prevents<\/b><\/a><\/p>\n

Often, <\/span>panic attacks<\/span> and anxiety are associated with sudden symptoms, and the <\/span>3-3-3 rule<\/span><\/a> may be beneficial. This tactic involves looking around and naming three things one sees, naming three sounds one hears, and moving three body parts, such as an ankle, finger, or arm. <\/span>Cognitive behavioral therapy<\/span><\/a> can be used in <\/span>mental health<\/span> conditions like depression, anxiety, substance use, and phobias. This form of therapy can help identify the thinking patterns that cause distress, manage overwhelming emotions, and reduce unhelpful behaviors.<\/span><\/p>\n

Diet modifications can be made to help prevent future <\/span>panic attacks<\/span>. According to the <\/span>American Addiction Centers<\/span><\/a>, alcohol use can cause new-onset anxiety and worsen pre-existing anxiety symptoms. Many individuals will use alcohol as an unhealthy coping tool to reduce <\/span>symptoms of anxiety<\/span>. Additionally, caffeine use may be associated with increased anxiety. The American Psychiatric Association recognizes <\/span>Caffeine-Induced <\/span>Anxiety Disorder<\/span><\/a> as a condition that involves the symptoms of either <\/span>panic attacks<\/span> or anxiety due to the consumption of caffeine. Avoiding or limiting alcohol and caffeine consumption may lessen <\/span>symptoms of anxiety<\/span>.<\/span><\/p>\n

RELATED: <\/b>Can caffeine cause anxiety?<\/b><\/a> | <\/b>5 ways to boost your mental health<\/b><\/a><\/p>\n

How to switch to a <\/span>clonazepam<\/span> alternative<\/span><\/h2>\n

1. Discuss all health conditions with a <\/span>healthcare provider<\/span><\/h3>\n

Before switching from <\/span>clonazepam<\/span> to an alternative, it\u2019s important to let your prescribing healthcare provider know about all of your health conditions. <\/span>SSRIs<\/span> and SNRIs such as fluoxetine, paroxetine, and venlafaxine may cause side effects such as sexual problems or insomnia. With a full review of an individual\u2019s health history, prescribers can make the most appropriate medication recommendations, so it is best to seek <\/span>medical advice<\/span> prior to changing medication therapy.<\/span><\/p>\n

2. Do not suddenly stop taking <\/span>clonazepam<\/span><\/h3>\n

Withdrawal syndrome can appear after <\/span>short-term<\/span> and <\/span>long-term use<\/span> of <\/span>clonazepam,<\/span> and the severity can depend on the dose, duration of the treatment, and the length of the taper period. <\/span>Withdrawal symptoms<\/span> may include sleep disturbance, irritability, increased tension and anxiety, <\/span>panic attacks<\/span>, hand tremor, sweating, difficulty in concentration, nausea, some weight loss, palpitations, headache, and muscular pain and stiffness. Abruptly stopping <\/span>clonazepam<\/span> may cause status epilepticus (a seizure requiring immediate medical attention).<\/span><\/p>\n

3. Discuss all prescription and <\/span>over-the-counter<\/span> medications with a <\/span>healthcare provider<\/span><\/h3>\n

Alternatives to <\/span>clonazepam<\/span> may have serious drug interactions when used with other <\/span>prescription drugs<\/span> and <\/span>over-the-counter<\/span> medications<\/span> or <\/span>supplements<\/span>. <\/span>Benzodiazepines<\/span> like <\/span>alprazolam<\/span>, <\/span>diazepam<\/span>, and <\/span>lorazepam<\/span> have serious risks if taken with <\/span>opioid pain medicines<\/span>. Using <\/span>benzodiazepines<\/span> with <\/span>opioids<\/span> can cause extreme <\/span>sedation<\/span>, respiratory depression, coma, and death.<\/span><\/p>\n

4. Start and continue to monitor <\/span>panic attack<\/span> symptoms<\/span><\/h3>\n

For people with <\/span>panic attacks<\/span>, it\u2019s important to find a <\/span>mental health<\/span> provider for managing symptoms and establishing a treatment plan. Treatment plans may include <\/span>anti-anxiety medication<\/span> and alternative remedies, including therapy. When looking for a place to start, there is an online resource provided by the <\/span>Substance Abuse and <\/span>Mental Health<\/span> Services Administration (SAMHSA)<\/span><\/a> that can help locate <\/span>mental health<\/span> treatment facilities and programs.\u00a0<\/span><\/p>\n

If clonazepam was originally prescribed for a seizure condition, consult your healthcare provider about other treatment options.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Clonazepam (brand name Klonopin) is a common medication used to help treat panic attacks and certain types of seizure disorders. Clonazepam belongs to the class of medications called benzodiazepines. Benzodiazepines work by increasing the effectiveness of the neurotransmitter gamma-aminobutyric acid (GABA), a chemical messenger in the brain, which controls the excitability of neurons. These medications […]<\/p>\n","protected":false},"author":133,"featured_media":53501,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[9777,451,450,4350],"coauthors":[20732],"class_list":["post-53499","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-anxiety","tag-depression","tag-mental-health","tag-prescription-savings","wpautop"],"acf":[],"yoast_head":"\nClonazepam alternatives and how to switch your Rx | SingleCare<\/title>\n<meta name=\"description\" content=\"Xanax, Valium, Prozac, Paxil, and Effexor XR are some clonazepam alternatives. 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Diazepam<\/span><\/a> is a <\/span>benzodiazepine<\/span> that is used to manage <\/span>anxiety disorders<\/span>, muscle spasms, procedural <\/span>sedation<\/span>, and seizure disorders, among other uses. Similar to <\/span>clonazepam and alprazolam<\/span>, <\/span>diazepam may cause<\/span> sedation<\/span>, <\/span>drowsiness<\/span>, fatigue, psychomotor <\/span>impairment<\/span>, and problems with memory and concentration. As similar medications, the <\/span>prescribing<\/span> preference between the two drugs may be determined by provider experience and the individual\u2019s response to treatment with one over the other. <\/span>Diazepam<\/span> is available in a variety of dosage forms, including tablets, oral solution, intramuscular injection, and rectal gel (used for seizures). Diazepam is one of the <\/span>longer-acting benzodiazepines<\/span><\/a>\u2014its effects can last up to 12 hours.<\/span><\/p>\n

1. <\/span>Xanax<\/span> (<\/span>alprazolam<\/span>)\u00a0<\/span><\/h3>\n

Alprazolam<\/span><\/a> is a <\/span>benzodiazepine<\/span> that is used to manage generalized <\/span>anxiety disorder<\/span> and <\/span>panic disorder in adults<\/span>. Similar to <\/span>clonazepam<\/span>, <\/span>alprazolam<\/span> can cause <\/span>sedation<\/span>, <\/span>drowsiness<\/span>, fatigue, psychomotor <\/span>impairment<\/span>, and problems with memory and concentration. As similar medications, the <\/span>prescribing<\/span> preference between the two drugs may be determined by provider experience and the individual\u2019s response to treatment with one over the other. <\/span>Alprazolam<\/span> is available in a variety of <\/span>dosage<\/span><\/a> forms, including tablets, extended-release tablets, orally disintegrating tablets, and oral solution (liquid). Alprazolam works quickly and wears off faster than other benzodiazepines, which is helpful for symptom relief\u2014but also makes it more likely to be misused or abused.<\/span><\/p>\n

RELATED: <\/b>Klonopin vs. Xanax: Differences, similarities, and which is better for you<\/b><\/a><\/p>\n