{"id":53510,"date":"2022-09-23T18:09:02","date_gmt":"2022-09-23T22:09:02","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53510"},"modified":"2025-03-21T14:18:06","modified_gmt":"2025-03-21T18:18:06","slug":"trulicity-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/trulicity-alternatives\/","title":{"rendered":"Trulicity alternatives: What can I take instead of Trulicity?"},"content":{"rendered":"

Weighing the advantages and disadvantages of <\/span>Trulicity<\/span><\/a> (dulaglutide) can be challenging for those who might be looking to switch to a different medication. On the positive side, Trulicity effectively lowers blood sugar by mimicking the effects of a hormone called glucagon-like peptide 1 (GLP-1). It also has some attractive side benefits, namely weight loss and a reduced risk of cardiovascular events like heart attacks and strokes.<\/span><\/p>\n

Although many people may find the once-weekly injection convenient, others may be turned off by the idea of an injection. In addition, some people may find the drug\u2019s <\/span>common side effects<\/span><\/a>, particularly nausea, intolerable, with the potential monetary costs being enough to bring many users to the brink of changing to an alternative.\u00a0<\/span><\/p>\n

What can I take in place of <\/span>Trulicity<\/span>?<\/span><\/h2>\n

If you’re looking for alternatives to Trulicity, other <\/span>GLP-1 receptor agonists<\/span><\/a> may work for you. Like Trulicity, these medications help control blood sugar by increasing insulin production and reducing glucagon release, which lowers blood sugar levels. They also slow digestion, making you feel full more quickly, which can help with weight loss and reduce the risk of low blood sugar. If you’re experiencing side effects with Trulicity or if your <\/span>insurance does not cover it<\/span><\/a>, trying a different GLP-1 medication could still be a good option.<\/span><\/p>\n

There are also other effective classes of medications for Type 2 diabetes if you want to explore other treatment options beyond GLP-1 agents. For example, <\/span>sodium-glucose cotransporter 2 (SGLT2) inhibitors<\/span><\/a> offer benefits for heart and kidney health, while dipeptidyl peptidase-4 (DPP-4) inhibitors are generally effective and well tolerated. In addition, generic versions of <\/span>sulfonylureas<\/span><\/a>, <\/span>biguanides<\/span><\/a>, <\/span>alpha-glucosidase inhibitors<\/span><\/a>, and <\/span>thiazolidinediones<\/span><\/a> can be effective while helping you save money.\u00a0<\/span><\/p>\n

Some medications combine two different classes into one pill, which may be helpful if you\u2019re on different medications for diabetes. Various types of insulin are also available for managing both <\/span>Type 1 and Type 2 diabetes<\/span><\/a>. Therefore, it may be worth comparing these options to find the best fit for your needs.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Compare Trulicity alternatives<\/span><\/th>\n<\/tr>\n<\/thead>\n
Drug name<\/b><\/td>\nUses<\/b><\/td>\nDosage<\/b><\/td>\nCoupons<\/b><\/td>\n<\/tr>\n
Trulicity<\/span> (<\/span>dulaglutide<\/span>)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, <\/span>cardiovascular<\/span> event risk reduction in those with <\/span>Type 2 diabetes<\/span> and <\/span>heart<\/span> disease or multiple <\/span>risk factors<\/span><\/td>\n0.75 to 4.5 mg <\/span>subcutaneous<\/span> (under the skin) injection once weekly<\/span><\/td>\nTrulicity<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Ozempic<\/span> (<\/span>semaglutide<\/span>)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, <\/span>cardiovascular<\/span> event risk reduction in those with <\/span>Type 2 diabetes<\/span> and <\/span>heart<\/span> disease, risk reduction of worsening kidney disease, kidney failure, and death in people with Type 2 diabetes and kidney disease<\/span><\/td>\n0.25 to 1 mg <\/span>subcutaneous<\/span> injection once weekly<\/span><\/td>\nOzempic<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Rybelsus<\/span> (<\/span>semaglutide<\/span>)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n3 to 14 mg once daily<\/span><\/td>\nRybelsus<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Victoza<\/span> (<\/span>liraglutide<\/span>)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, <\/span>cardiovascular<\/span> event risk reduction in those with <\/span>Type 2 diabetes<\/span> and <\/span>heart<\/span> disease<\/span><\/td>\n0.6 to 1.8 mg <\/span>subcutaneous<\/span> injection once daily<\/span><\/td>\nVictoza<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Mounjaro (tirzepatide)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n2.5 to 15 mg <\/span>subcutaneous<\/span> injection once weekly<\/span><\/td>\nMounjaro coupons<\/span><\/a><\/td>\n<\/tr>\n
Farxiga<\/span> (dapagliflozin)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, heart failure risk reduction in <\/span>Type 2 diabetes mellitus<\/span> with <\/span>heart disease<\/span> or multiple <\/span>cardiovascular<\/span> risk factors<\/span>, heart failure risk reduction in those with reduced cardiac ejection fractions, heart failure and kidney disease progression risk reduction in those with chronic kidney disease<\/span><\/td>\n5 to 10 mg once daily<\/span><\/td>\nFarxiga<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Jardiance<\/span> (<\/span>empagliflozin<\/span>)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, <\/span>cardiovascular<\/span> event risk reduction in people with <\/span>Type 2 diabetes and heart disease<\/span>, heart failure risk reduction in those with reduced cardiac ejection fractions<\/span><\/td>\n10 25 mg once daily<\/span><\/td>\nJardiance<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Invokana (canagliflozin)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, <\/span>cardiovascular<\/span> event risk reduction in <\/span>Type 2 diabetes mellitus<\/span> with <\/span>heart<\/span> disease, kidney disease progression risk reduction, and <\/span>cardiovascular<\/span> event risk reduction in those with <\/span>Type 2 diabetes mellitus<\/span> and diabetic kidney disease with albuminuria >300 mg\/day<\/span><\/td>\n100 to 300 mg once daily<\/span><\/td>\nInvokana coupons<\/span><\/a><\/td>\n<\/tr>\n
Glucotrol (glipizide)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n5 to 40 mg daily in two divided doses<\/span><\/td>\nGlipizide<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Amaryl (glimepiride)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n1 to 8 mg once daily<\/span><\/td>\nAmaryl coupons<\/span><\/a><\/td>\n<\/tr>\n
Prandin (repaglinide)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n0.5 to 4 mg before meals up to four times daily<\/span><\/td>\nRepaglinide coupons<\/span><\/a><\/td>\n<\/tr>\n
Glucophage (metformin)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n500 mg twice daily or 850 mg once daily<\/span><\/td>\nMetformin<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Januvia<\/span> (sitagliptin)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n100 mg once daily<\/span><\/td>\nJanuvia<\/span> coupons<\/span><\/a><\/td>\n<\/tr>\n
Actos (<\/span>pioglitazone<\/span>)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n15 to 45 mg once daily<\/span><\/td>\nActos coupons<\/span><\/a><\/td>\n<\/tr>\n
Lantus Solostar (insulin glargine)<\/span><\/td>\nType 2 diabetes mellitus<\/span>, <\/span>Type 1 diabetes<\/span> mellitus<\/span><\/td>\nIndividualized dose injected <\/span>subcutaneously<\/span> once daily<\/span><\/td>\nLantus Solostar coupons<\/span><\/a><\/td>\n<\/tr>\n
Xigduo XR (dapagliflozin\/metformin)<\/span><\/td>\nType 2 diabetes mellitus<\/span><\/td>\n5\/500 mg to 10\/2000 mg once daily<\/span><\/td>\nXigduo XR coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Other alternatives to <\/span>Trulicity<\/span><\/h3>\n