{"id":53923,"date":"2022-10-06T00:23:13","date_gmt":"2022-10-06T04:23:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=53923"},"modified":"2024-11-13T17:11:33","modified_gmt":"2024-11-13T22:11:33","slug":"lamotrigine-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/lamotrigine-alternatives\/","title":{"rendered":"Lamotrigine alternatives: What can I take instead of lamotrigine?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\"><a href=\"#compare-lamotrigine-alternatives\"> Compare lamotrigine alternatives<\/a> | <a href=\"#lithium\">Lithium<\/a> | <a href=\"#depakote\">Depakote<\/a> | <a href=\"#tegretol\">Tegretol<\/a> | <a href=\"#seroquel\">Seroquel<\/a> | <a href=\"#keppra\">Keppra<\/a> | <a href=\"#natural-alternatives\">Natural alternatives<\/a> | <a href=\"#how-to-switch-meds\">How to switch meds<\/a><\/span><\/p>\n<p><span style=\"font-weight: 400;\">Anyone can feel reluctant to change medication for their bipolar disorder or seizures. Those two conditions are frightening to experience, and altering the treatment plan could make you susceptible to a relapse of seizures or mental health problems. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lamotrigine\/what-is\"><span style=\"font-weight: 400;\">Lamotrigine<\/span><\/a><span style=\"font-weight: 400;\">, the generic form of brand name <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lamictal\/what-is\"><span style=\"font-weight: 400;\">Lamictal<\/span><\/a><span style=\"font-weight: 400;\">, has Food and Drug Administration (FDA) approval for maintenance treatment of both bipolar I disorder and prevention of seizures. Although many find Lamictal helpful, you may not and could rightfully be considering a switch to a different drug. Lamictal may simply be ineffective, prompting you to want something better, or it could be causing you unacceptable side effects. But even if your reason for looking into an alternative is justified, it is crucial to understand the options in detail and take your ideas to a healthcare provider before making any changes. Those details are exactly what we will cover.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What can I take in place of lamotrigine?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Lamotrigine is categorized as an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/anticonvulsants\"><span style=\"font-weight: 400;\">anticonvulsant<\/span><\/a><span style=\"font-weight: 400;\">, a drug used to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/epilepsy-treatment-and-medications\"><span style=\"font-weight: 400;\">epilepsy<\/span><\/a><span style=\"font-weight: 400;\">. Anticonvulsants or antiepileptic drugs are a broad category with various mechanisms for blocking the repetitive firing of neurons (brain cells) that causes seizures. If Lamictal is not the right choice for you, there are a number of alternatives to look into. Most are not overly expensive, but a <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare discount card<\/span><\/a><span style=\"font-weight: 400;\"> may still be advisable to help reduce the cost.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Treatment of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/bipolar-disorder-treatment-and-medications\"><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/a><span style=\"font-weight: 400;\"> often incorporates a <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/mood-stabilizers\"><span style=\"font-weight: 400;\">mood stabilize<\/span><\/a><span style=\"font-weight: 400;\">r as a core element. Certain anticonvulsants, including Lamictal, can function as mood stabilizers. Changing to a different anticonvulsant or a different type of mood stabilizer could be options for you. Aside from mood stabilizers, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">antipsychotic drugs<\/span><\/a><span style=\"font-weight: 400;\"> are another category that is effective for bipolar disorder and may be a worthy substitute for Lamictal. Comparing your options will hopefully help you find the right one.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/news\/bipolar-disorder-statistics\/\"><b>Bipolar disorder statistics 2022<\/b><\/a><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"compare-lamotrigine-alternatives\"><span class=\"title\">Compare lamotrigine alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td>Lamictal (lamotrigine)<\/td>\n<td>Bipolar I disorder maintenance, partial or generalized seizures<\/td>\n<td>100 to 400 mg daily divided into one or two doses<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lamictal\">Lamictal coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Lamictal XR (lamotrigine extended-release)<\/td>\n<td>Partial or generalized seizures<\/td>\n<td>200 to 600 mg once daily dependent on clinical scenario<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lamictal-xr\">Lamictal XR coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Lithium<\/td>\n<td>Bipolar I disorder maintenance or acute mania<\/td>\n<td>600 to 1800 mg daily divided into two or three doses<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lithium-carbonate\">Lithium coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Depakote (divalproex sodium)<\/td>\n<td>Bipolar disorder acute mania, partial or absence seizures, migraine headache prophylaxis<\/td>\n<td>250 to 500 mg three times daily for mania, 30 to 60 mg per kg of body weight per day and divided into two or three doses for seizures, 250 to 500 mg twice daily for migraines<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/depakote\">Depakote coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Depakote ER (divalproex extended-release)<\/td>\n<td>Bipolar disorder acute mania, partial or absence seizures, migraine headache prophylaxis<\/td>\n<td>25 to 60 mg per kg of body weight per day taken once daily for mania, 30 to 60 mg per kg of body weight per day taken once daily for seizures, 500 to 1000 mg once daily for migraines<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/depakote-er\">Depakote ER coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Seroquel (quetiapine)<\/td>\n<td>Bipolar I disorder mania, bipolar I disorder depression, schizophrenia<\/td>\n<td>200 to 400 mg twice daily for mania, 300 mg once daily for bipolar depression, 150 to 750 mg daily divided into two or three doses for schizophrenia<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/seroquel\">Seroquel coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Seroquel XR (quetiapine extended-release)<\/td>\n<td>Bipolar I disorder mania, bipolar I disorder depression, major depressive disorder adjunct, schizophrenia<\/td>\n<td>400 to 800 mg once daily for mania or schizophrenia, 300 mg once daily for bipolar depression, 150 to 300 mg once daily for major depression adjunct<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/seroquel-xr\">Seroquel XR coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Abilify (aripiprazole)<\/td>\n<td>Bipolar I disorder mania, major depressive disorder adjunct, schizophrenia<\/td>\n<td>15 to 30 mg once daily for mania, 10 to 15 mg once daily for schizophrenia, 2 to 15mg once daily for major depression adjunct<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/abilify\">Abilify coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Zyprexa (olanzapine)<\/td>\n<td>Bipolar I disorder mania, bipolar I disorder depression, schizophrenia, treatment resistant major depressive disorder adjunct<\/td>\n<td>5 to 20 mg once daily for mania, bipolar depression, or treatment resistant depression adjunct; 10 mg once daily for schizophrenia<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa\">Zyprexa coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Risperdal (risperidone)<\/td>\n<td>Bipolar I disorder mania, schizophrenia<\/td>\n<td>1 to 6 mg daily divided into one or two doses<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/risperdal\">Risperdal coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Latuda (lurasidone)<\/td>\n<td>Bipolar I disorder depression, schizophrenia<\/td>\n<td>20 to 120 mg once daily for bipolar depression, 40 to 160 mg once daily for schizophrenia<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/latuda\">Latuda coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Tegretol (carbamazepine)<\/td>\n<td>Seizure disorder, trigeminal neuralgia, bipolar disorder (<a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\">off-label<\/a>)<\/td>\n<td>800 to 1200 mg daily divided into two to four doses for seizures or bipolar, 200 to 400 mg twice daily for trigeminal neuralgia<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/tegretol\">Tegretol coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Tegretol XR (carbamazepine extended-release)<\/td>\n<td>Seizure disorder, trigeminal neuralgia<\/td>\n<td>400 to 600 mg twice daily for seizures, 200 to 400 mg twice daily for trigeminal neuralgia<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/tegretol-xr\">Tegretol XR coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Topamax (topiramate)<\/td>\n<td>Partial or generalized seizures, migraine headache prophylaxis<\/td>\n<td>200 mg twice daily for seizures, 50 mg twice daily for migraine prophylaxis<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/topamax\">Topamax coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Trokendi XR (topiramate extended-release)<\/td>\n<td>Partial or generalized seizures, migraine headache prophylaxis<\/td>\n<td>200 to 400 mg once daily for seizures, 100 mg once daily for migraine prophylaxis<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/trokendi-xr\">Trokendi XR coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Vimpat (lacosamide)<\/td>\n<td>Partial or generalized seizures<\/td>\n<td>100 to 200 mg twice daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/vimpat\">Vimpat coupons<\/a><\/td>\n<\/tr>\n<tr>\n<td>Keppra (levetiracetam)<\/td>\n<td>Partial or generalized seizures<\/td>\n<td>500 to 1500 mg twice daily<\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/keppra\">Keppra coupons<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3><span style=\"font-weight: 400;\">Other alternatives to lamotrigine<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/haloperidol\"><span style=\"font-weight: 400;\">Haloperidol<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/geodon\"><span style=\"font-weight: 400;\">Geodon<\/span><\/a><span style=\"font-weight: 400;\"> (ziprasidone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/clozaril\"><span style=\"font-weight: 400;\">Clozaril<\/span><\/a><span style=\"font-weight: 400;\"> (clozapine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/fycompa\"><span style=\"font-weight: 400;\">Fycompa<\/span><\/a><span style=\"font-weight: 400;\"> (perampanel)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/mysoline\"><span style=\"font-weight: 400;\">Mysoline<\/span><\/a><span style=\"font-weight: 400;\"> (primidone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/phenobarbital\"><span style=\"font-weight: 400;\">Phenobarbital<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/klonopin\"><span style=\"font-weight: 400;\">Klonopin<\/span><\/a><span style=\"font-weight: 400;\"> (clonazepam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/onfi\"><span style=\"font-weight: 400;\">Onfi<\/span><\/a><span style=\"font-weight: 400;\"> (clobazam)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/felbatol\"><span style=\"font-weight: 400;\">Felbatol<\/span><\/a><span style=\"font-weight: 400;\"> (felbamate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/xcopri\"><span style=\"font-weight: 400;\">Xcompri<\/span><\/a><span style=\"font-weight: 400;\"> (cenobamate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/trileptal\"><span style=\"font-weight: 400;\">Trileptal<\/span><\/a><span style=\"font-weight: 400;\"> (oxcarbazepine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/valproic-acid\"><span style=\"font-weight: 400;\">Valproic acid<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/valproate-sodium\"><span style=\"font-weight: 400;\">Valproate<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/neurontin\"><span style=\"font-weight: 400;\">Neurontin<\/span><\/a><span style=\"font-weight: 400;\"> (gabapentin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/dilantin\"><span style=\"font-weight: 400;\">Dilantin<\/span><\/a><span style=\"font-weight: 400;\"> (phenytoin)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/keppra-xr\"><span style=\"font-weight: 400;\">Keppra XR<\/span><\/a><span style=\"font-weight: 400;\"> (levetiracetam extended release)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/briviact\"><span style=\"font-weight: 400;\">Briviact<\/span><\/a><span style=\"font-weight: 400;\"> (brivaracetam)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our mental health newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Mental Health Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Top 5 lamotrigine alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most common alternatives to lamotrigine.<\/span><\/p>\n<h3 id=\"lithium\"><span style=\"font-weight: 400;\">1. Lithium<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/lithium-carbonate\/what-is\"><span style=\"font-weight: 400;\">Lithium<\/span><\/a><span style=\"font-weight: 400;\"> is a long-standing, well-studied mood stabilizer for bipolar disorder. How exactly it works remains a mystery, but its efficacy is undeniable. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17547586\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Clinical trials<\/span><\/a><span style=\"font-weight: 400;\"> have shown that lithium and Lamictal are equally good at reducing the overall risk of relapse, although lithium seems a bit better at lowering risk of mania recurrence. If Lamictal is not working for you, lithium is certainly an alternative to be aware of.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Unfortunately, lithium has a multitude of side effects which make it less tolerable than the effects of Lamictal in <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20712749\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">studies<\/span><\/a><span style=\"font-weight: 400;\">. Potential adverse effects of lithium on kidney, thyroid, and parathyroid function can be problematic, as can untoward symptoms like diarrhea, nausea, tremor, and weight gain. Toxic effects of lithium are experienced at drug levels not much higher than those required for effectiveness. Accordingly, lithium drug levels are monitored with bloodwork to help avoid toxicity. When done right, lithium therapy can be a good choice, but the prospect of serious side effects and drug monitoring may keep you looking for other options.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/lithium-side-effects\/\"><b>Lithium side effects and how to avoid them<\/b><\/a><\/p>\n<h3 id=\"depakote\"><span style=\"font-weight: 400;\">2. Depakote<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Divalproex sodium is the generic form of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/depakote\/what-is\"><span style=\"font-weight: 400;\">Depakote<\/span><\/a><span style=\"font-weight: 400;\"> and is chemically similar to valproate and valproic acid. Depakote shares both seizure and bipolar treatment indications with lamotrigine. They both are anticonvulsants that are effective in preventing seizures in epilepsy and mood stabilizers that are effective for preventing mood swings in bipolar disorder. Extended-release formulations are available for both, if the convenience of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/depakote\/dosage\"><span style=\"font-weight: 400;\">once-daily dosing<\/span><\/a><span style=\"font-weight: 400;\"> is important. <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24132760\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Depakote<\/span><\/a><span style=\"font-weight: 400;\"> and Lamictal can each match lithium for efficacy and surpass it for tolerability.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Given all the similarities, the reason to consider changing from Lamictal to Depakote is the difference in side effects and potential allergic reactions. Either can make you nauseous, dizzy, tremulous, or cause blurred vision, but there are serious toxicities that each is notorious for. Lamotrigine has a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\"> from the FDA for the potential to cause the life-threatening skin rash condition Stevens Johnson syndrome and others like it. It can also provoke substantial adverse effects on the heart. In comparison, the black box warning on <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/divalproex-sodium\/what-is\"><span style=\"font-weight: 400;\">Divalproex<\/span><\/a><span style=\"font-weight: 400;\"> is regarding the potential for hepatotoxicity, including fatal liver failure, and pancreatitis, an attack of pancreas inflammation. It can trigger dangerous drops in blood cell counts as well. A pre-existing medical condition or bad initial experience with Lamictal could sway you toward Depakote.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/depakote-side-effects\/\"><b>Depakote side effects and how to avoid them<\/b><\/a><\/p>\n<h3 id=\"tegretol\"><span style=\"font-weight: 400;\">3. Tegretol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Another anticonvulsant\/mood stabilizer with a potential for life threatening rashes, blood cell count disturbances, and liver effects, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/tegretol\/what-is\"><span style=\"font-weight: 400;\">Tegretol<\/span><\/a><span style=\"font-weight: 400;\"> does not immediately distinguish itself from Lamictal and Depakote. Like them, it has a generic form and extended-release product too. Sometimes the reason to change may simply be to try to find something that works better. While <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/carbamazepine\/what-is\"><span style=\"font-weight: 400;\">carbamazepine<\/span><\/a><span style=\"font-weight: 400;\">, the generic form of Tegretol, is a <\/span><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/epi.12074\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">common first-line option<\/span><\/a><span style=\"font-weight: 400;\"> for epilepsy, it is not usually an early choice for bipolar disorder. A reason to hesitate regarding carbamazepine is the large list of meds that interact with it. The search for the right medication must take into account your list of prescription drugs and over-the-counter medications to evaluate for drug interactions.<\/span><\/p>\n<h3 id=\"seroquel\"><span style=\"font-weight: 400;\">4. Seroquel<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/seroquel\/what-is\"><span style=\"font-weight: 400;\">Seroquel<\/span><\/a><span style=\"font-weight: 400;\"> (quetiapine) is solely an alternative to Lamictal for those with bipolar mood disorder. It is not an anticonvulsant. Quetiapine is a second generation or <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/atypical-antipsychotics\"><span style=\"font-weight: 400;\">atypical antipsychotic<\/span><\/a><span style=\"font-weight: 400;\">, but it is a popular mood stabilizer for those with bipolar. The popularity likely stems from its ability to treat both manic episodes and depressive symptoms of bipolar. Limitations that you should be aware of are its propensity to cause tiredness and weight gain.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/seroquel-side-effects\/\"><b>Seroquel side effects and how to avoid them<\/b><\/a><\/p>\n<h3 id=\"keppra\"><span style=\"font-weight: 400;\">5. Keppra<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If you are searching for an alternative to Lamictal for epilepsy control rather than bipolar, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/keppra\/what-is\"><span style=\"font-weight: 400;\">Keppra<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/levetiracetam\/what-is\"><span style=\"font-weight: 400;\">levetiracetam<\/span><\/a><span style=\"font-weight: 400;\">) is worth a look. Levetiracetam\u2019s efficacy and tolerability leads many who start it to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2117408\/\"><span style=\"font-weight: 400;\">stick with it<\/span><\/a><span style=\"font-weight: 400;\">. Other attractive features are the lack of a FDA black box warning and a relative paucity of contraindications and drug interactions compared to lamotrigine. Before choosing Keppra, you should review the <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15304598\/\"><span style=\"font-weight: 400;\">common side effects<\/span><\/a><span style=\"font-weight: 400;\">, including sedation and mood disturbance. Caution when starting any of these drugs is advisable, because excessive tiredness could cause impairment with driving and other tasks.<\/span><\/p>\n<h2 id=\"natural-alternatives\"><span style=\"font-weight: 400;\">Natural alternatives to lamotrigine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Facing warning labels, serious side effects, drug interactions, and contraindications could have you fearful of just about any medication. For that reason, many folks turn to natural alternatives. However, just because something is considered natural does not mean it is safe. Many supplements have not been adequately tested either. A <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24353094\/\"><span style=\"font-weight: 400;\">review of supplements for bipolar depression<\/span><\/a><span style=\"font-weight: 400;\"> reached the conclusion that there is not enough evidence to support any particular one, but it also pointed out that natural options can have potential, as evidenced by the mood stabilizer lithium being a natural mineral.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Cannabidiol (CBD) garners a lot of attention as a potential, natural remedy for bipolar and seizure disorders. Only weak evidence exists for use in bipolar treatment, according to a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7819291\/\"><span style=\"font-weight: 400;\">2020 review<\/span><\/a><span style=\"font-weight: 400;\">. Likewise, a <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33347884\/\"><span style=\"font-weight: 400;\">review<\/span><\/a><span style=\"font-weight: 400;\"> indicated that the use of CBD for certain seizure disorders is backed by clinical trials, but numerous questions remain about its safety and effectiveness.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/the-best-diet-for-mental-health\/\"><b>The best diet for mental health<\/b><\/a><b> | <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/depression-caused-by-physical-illness\/\"><b>Physical activity and mental health<\/b><\/a><\/p>\n<h2 id=\"how-to-switch-meds\"><span style=\"font-weight: 400;\">How to switch to a lamotrigine alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The gravity of a decision about seizure or bipolar treatment can seem overwhelming. Hopefully, gathering information has helped to put you on the right track in the decision-making process. The next step is to discuss the matter with the prescribing healthcare professional. If the effects of lamotrigine have you considering discontinuation, be prepared to explain why you are dissatisfied and what you are looking for in a substitute, including any of the options noted above. Your pharmacist can be another great resource for medical advice. When a decision is made, your entire healthcare team should be on the same page.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Compare lamotrigine alternatives | Lithium | Depakote | Tegretol | Seroquel | Keppra | Natural alternatives | How to switch meds Anyone can feel reluctant to change medication for their bipolar disorder or seizures. Those two conditions are frightening to experience, and altering the treatment plan could make you susceptible to a relapse of seizures [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":53927,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[451,450,20802],"coauthors":[20732],"class_list":["post-53923","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-depression","tag-mental-health","tag-seizures","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top lamotrigine alternatives and how to switch your Rx | SingleCare<\/title>\n<meta name=\"description\" content=\"Lithium, Depakote, Tegretol, Seroquel, and Keppra are some lamotrigine alternatives.\" 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