{"id":54374,"date":"2022-10-05T09:30:20","date_gmt":"2022-10-05T13:30:20","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=54374"},"modified":"2022-11-18T15:03:45","modified_gmt":"2022-11-18T20:03:45","slug":"phentermine-and-caffeine","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/phentermine-and-caffeine\/","title":{"rendered":"Is it safe to mix phentermine and caffeine?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you are someone who takes phentermine for weight management, you might be wondering if it\u2019s okay to have a cup of coffee every now and then. How about tea, soda, or other forms of caffeine? After all, phentermine is a<\/span>\u00a0<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fphar.2016.00105\/full\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">stimulant<\/span><\/a><span style=\"font-weight: 400;\"> and can have some of the same<\/span> <a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682187.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> as caffeine, such as rapid heartbeat and jitteriness. Is it possible that combining phentermine and coffee will have some unpleasant\u2014or even harmful\u2014side effects?<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Let\u2019s take a look at what happens when you mix phentermine and caffeine, and whether you can drink caffeine while taking <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/phentermine-hcl\"><span style=\"font-weight: 400;\">phentermine<\/span><\/a><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">What is phentermine?<\/span><\/h2>\n<p><a href=\"https:\/\/www.singlecare.com\/prescription\/phentermine-hcl\/what-is\"><span style=\"font-weight: 400;\">Phentermine<\/span><\/a><span style=\"font-weight: 400;\"> is a medication that can suppress your appetite. It\u2019s often used to help overweight or obese people who are having trouble losing weight. The medication is usually combined with other weight loss strategies such as calorie reduction and exercise. If you\u2019re wondering how much caffeine is in phentermine, the answer is zero. Phentermine doesn\u2019t have caffeine in it, but like caffeine, it\u2019s a stimulant, and has many of the same side effects as caffeine.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/blog\/phentermine-for-weight-loss\/\"><b>Is phentermine for weight loss safe?<\/b><\/a><\/p>\n<h2><span style=\"font-weight: 400;\">Do phentermine and caffeine interact?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There is little published data out there to answer questions like, \u201cCan you drink coffee with phentermine?\u201d But in theory, phentermine and caffeine could interact with each other, says<\/span> <a href=\"https:\/\/www.linkedin.com\/in\/laura-purdy-md\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Laura Purdy<\/span><\/a><span style=\"font-weight: 400;\">, MD, a board-certified family medicine physician.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The reason for this, Dr. Purdy says, is because both phentermine and caffeine stimulate the nervous system, and if combined together, you could potentially experience intense side effects. \u201cI would expect that someone who is using phentermine and also chooses to take caffeine will have a very high blood pressure and heart rate, likely palpitations, have trouble with sleeping, and will likely have racing thoughts and a dry mouth,\u201d Dr. Purdy explains.<\/span><\/p>\n<h3><span style=\"font-weight: 400;\">Does caffeine interact with topiramate?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Phentermine is often combined with <\/span><span style=\"font-weight: 400;\">topiramate to maximize effects in people looking to lose weight. In 2012, the FDA approved a combination drug called Qsymia, which contains phentermine and topiramate, to be used as an appetite suppressant. As such, if you are taking topiramate along with <\/span><span style=\"font-weight: 400;\">phentermine,<\/span><span style=\"font-weight: 400;\"> you may be wondering if you can consume caffeine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">According to Erika Gray, Pharm.D., chief medical officer and co-founder of<\/span> <a href=\"http:\/\/toolboxgenomics.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Toolbox Genomics<\/span><\/a><span style=\"font-weight: 400;\">, there is some<\/span> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29414557\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">research indicating<\/span><\/a><span style=\"font-weight: 400;\"> caffeine interacts with topiramate by making it less effective. \u201cThis is especially problematic if you take topiramate for seizures,\u201d she says. (Topamax, a single-ingredient drug that contains the active ingredient topiramate, is used to treat certain types of seizures.) However, she notes that there isn\u2019t any research showing that caffeine decreases the effectiveness of topiramate when it comes to appetite suppression.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">How much caffeine can you have with phentermine?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are no set rules about how much caffeine you can consume with phentermine, says Dr. Purdy. Still, she recommends using precautions. \u201cI would really advise that people drastically cut back, and they probably won\u2019t even feel like they need caffeine when they are taking phentermine,\u201d she explains.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It&#8217;s also important to remember that not all caffeine sources have the same amount of caffeine in them. \u201cA Starbucks quadruple espresso has much more caffeine than a cup of green tea,\u201d says Dr. Purdy. It\u2019s possible there is a dose dependent impact when it comes to mixing phentermine and caffeine. \u201cThe more that you take, the more symptoms of caffeine excess or stimulant excess the person may have,\u201d she explains.<\/span><b>\u00a0<\/b><\/p>\n<h2><span style=\"font-weight: 400;\">How does caffeine affect people on appetite suppressants?<\/span><b>\u00a0<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Phentermine isn\u2019t the only stimulant appetite suppressant medication out there. The FDA has approved other stimulant medications for weight management,<\/span> <a href=\"https:\/\/www.niddk.nih.gov\/health-information\/weight-management\/prescription-medications-treat-overweight-obesity\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">such as<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/diethylpropion-hcl\"><span style=\"font-weight: 400;\">Diethylpropion<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/phendimetrazine-tartrate\"><span style=\"font-weight: 400;\">Phendimetrazine<\/span><\/a><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Appetite suppressants are meant to be used along with exercise and diet to help you lose weight, explains<\/span> <a href=\"https:\/\/mdmercy.com\/find-a-doctor\/sabrina-barata-md\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Sabrina Barata<\/span><\/a><span style=\"font-weight: 400;\">, MD, a primary care doctor at Mercy Personal Physicians at Lutherville in Maryland. \u201cThey help you suppress your appetite by stimulating your central nervous system and therefore reducing your appetite,\u201d she says. \u201cThese medications essentially function as a stimulant.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Again, the problem here is that caffeine is also a stimulant, which is why caffeine should be taken with caution anytime you are on a stimulant appetite suppressant, says Dr. Barata. \u201cYou should discuss with your doctor prior to initiation of any appetite suppressant in regards to any dietary modifications and caffeine use,\u201d she recommends.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Any excessive caffeine use can lead to increased heart rate and elevated blood pressure, and people with medical conditions like thyroid disease, heart disease, glaucoma, and a history of seizures may be most vulnerable to these effects, Dr. Barata adds.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Note: There are other medications used for weight loss, such as <a href=\"https:\/\/www.singlecare.com\/blog\/contrave-vs-phentermine\/\">Contrave (naltrexone\/bupropion)<\/a>, Wegovy (semaglutide), or Saxenda (liraglutide). These drugs work differently than phentermine and are not stimulants. However, Contrave and caffeine can interact, increasing the risk of high blood pressure.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Best practices for taking phentermine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">For best results, you should follow the specific instructions for the type of phentermine you are taking.<\/span> <a href=\"https:\/\/medlineplus.gov\/druginfo\/meds\/a682187.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Phentermine<\/span><\/a> <span style=\"font-weight: 400;\">is often taken as a single dose first thing in the morning. It also may be taken as several doses throughout the day, usually about 30 minutes before a meal. Because side effects of phentermine include wakefulness and insomnia, it\u2019s recommended that you take phentermine in the morning, and not at bedtime.<\/span><b>\u00a0<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Anytime you are taking a new medication, you should discuss with your healthcare provider how it may interact with substances like caffeine, along with any other substances, foods, medications (Rx or OTC), or vitamins you may be consuming.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When it comes to phentermine, there aren\u2019t any foods or vitamins that are known to have harmful side effects, explains Dr. Gray. But she says it\u2019s always sensible to be cautious around substances like alcohol. \u201cI always exercise extreme caution with my patients who consume alcohol and any medications\u2014phentermine is no exception,\u201d Dr. Gray offers.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Barata says that your healthcare provider may have specific recommendations about what foods to consume while on phentermine as you aim to reach your goal of losing weight in a safe and steady manner. \u201cYour doctor may mention to avoid certain foods in regards to your diet meal plan while on phentermine to avoid changes in your blood sugar level, which may affect your overall weight loss, excessive fat storage, and therefore decreasing effectiveness of phentermine,\u201d she says.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For example, simple carbohydrates and sugary, processed foods may be advised against, because of how they may affect your sugar levels, Dr. Barata says. It should also be noted that constipation is a common side effect of phentermine, so you should be sure to increase your fiber intake while taking it, as well as drink plenty of water. If you become seriously constipated, talk to your healthcare provider about using stool softeners, Dr. Barata recommends.<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The recommendations about what to consume and what not to consume while taking phentermine will vary from one person to another, based on their medical history, and nutritional needs. If you have any further questions about mixing phentermine with caffeine\u2014or any other dietary considerations while taking this medication\u2014be sure to reach out to your healthcare provider.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you are someone who takes phentermine for weight management, you might be wondering if it\u2019s okay to have a cup of coffee every now and then. How about tea, soda, or other forms of caffeine? After all, phentermine is a\u00a0stimulant and can have some of the same side effects as caffeine, such as rapid [&hellip;]<\/p>\n","protected":false},"author":94,"featured_media":54189,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[788,8905],"coauthors":[20899],"class_list":["post-54374","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-drug-safety","tag-seasonal","franchise-the-jolt","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Is it safe to mix phentermine and caffeine?<\/title>\n<meta name=\"description\" content=\"Caffeine may increase the side effects of phentermine but there are no known interactions. Learn how to safely consume caffeine with phentermine.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/phentermine-and-caffeine\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Do caffeine and phentermine mix?\" \/>\n<meta property=\"og:description\" content=\"There may be side effects of combining these 2 stimulants\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.singlecare.com\/blog\/phentermine-and-caffeine\/\" \/>\n<meta property=\"og:site_name\" content=\"The Checkup\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/singlecare\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-05T13:30:20+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-18T20:03:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/09\/Blog_100522_phentermine_caffeine_mix.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1080\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Wendy Wisner\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Do caffeine and phentermine mix?\" \/>\n<meta name=\"twitter:description\" content=\"There may be side effects of combining these 2 stimulants\" \/>\n<meta name=\"twitter:creator\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:site\" content=\"@SingleCare\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Wendy Wisner\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/\"},\"author\":{\"name\":\"Mariusz Labedzki\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#\\\/schema\\\/person\\\/232380d21234706e6360acfa9c895934\"},\"headline\":\"Is it safe to mix phentermine and caffeine?\",\"datePublished\":\"2022-10-05T13:30:20+00:00\",\"dateModified\":\"2022-11-18T20:03:45+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/\"},\"wordCount\":1194,\"publisher\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/Blog_100522_phentermine_caffeine_mix.png\",\"keywords\":[\"Drug safety\",\"Seasonal\"],\"articleSection\":[\"Drug Info\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/\",\"name\":\"Is it safe to mix phentermine and caffeine?\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/phentermine-and-caffeine\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/wp-content\\\/uploads\\\/2022\\\/09\\\/Blog_100522_phentermine_caffeine_mix.png\",\"datePublished\":\"2022-10-05T13:30:20+00:00\",\"dateModified\":\"2022-11-18T20:03:45+00:00\",\"description\":\"Caffeine may increase the side effects of phentermine but there are no known interactions. 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