{"id":54851,"date":"2022-10-27T21:02:01","date_gmt":"2022-10-28T01:02:01","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=54851"},"modified":"2025-02-19T16:15:28","modified_gmt":"2025-02-19T21:15:28","slug":"rybelsus-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/rybelsus-side-effects\/","title":{"rendered":"Rybelsus side effects and how to avoid them"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/rybelsus\"><span style=\"font-weight: 400;\">Rybelsus<\/span><\/a><span style=\"font-weight: 400;\"> is a brand-name <\/span><span style=\"font-weight: 400;\">prescription drug<\/span><span style=\"font-weight: 400;\"> that, along with diet and exercise, helps to control <\/span><span style=\"font-weight: 400;\">high blood sugar<\/span><span style=\"font-weight: 400;\"> in people with <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/type-2-diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Type 2 diabetes mellitus<\/span><\/a><span style=\"font-weight: 400;\">. Its active ingredient, <\/span><span style=\"font-weight: 400;\">semaglutide<\/span><span style=\"font-weight: 400;\">, belongs to a family of diabetes drugs called <\/span><span style=\"font-weight: 400;\">glucagon-like peptide-1<\/span> <span style=\"font-weight: 400;\">receptor agonists,<\/span><span style=\"font-weight: 400;\"> known as <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/glp-1-agonists\/\"><span style=\"font-weight: 400;\">GLP-1<\/span><span style=\"font-weight: 400;\"> agonists<\/span><\/a><span style=\"font-weight: 400;\">. These drugs <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=27f15fac-7d98-4114-a2ec-92494a91da98\"><span style=\"font-weight: 400;\">increase the body\u2019s production of insulin and decrease the body\u2019s production of <\/span><span style=\"font-weight: 400;\">glucose<\/span><\/a><span style=\"font-weight: 400;\"> when blood sugar goes up after a meal. <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is taken orally once daily as a tablet. However, <\/span><span style=\"font-weight: 400;\">semaglutide<\/span><span style=\"font-weight: 400;\"> is also administered as a brand-name injection called <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic-0-25-or-0-5-mg-dose\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\">, also used to treat <\/span><span style=\"font-weight: 400;\">Type 2 diabetes<\/span><span style=\"font-weight: 400;\">, or <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/wegovy\"><span style=\"font-weight: 400;\">Wegovy<\/span><\/a><span style=\"font-weight: 400;\">, used for <\/span><span style=\"font-weight: 400;\">weight loss<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Side effects<\/span><span style=\"font-weight: 400;\"> are commonly experienced, and some can be serious, so <\/span><span style=\"font-weight: 400;\">GLP-1<\/span><span style=\"font-weight: 400;\"> agonists come with some safety warnings from the <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>RELATED: <\/b><a href=\"https:\/\/www.singlecare.com\/prescription\/rybelsus\/what-is\"><b>What is <\/b><b>Rybelsus<\/b><b>?<\/b><\/a><\/p>\n<h2 id=\"common-side-effects-of-rybelsus\"><span style=\"font-weight: 400;\">Common side effects of Rybelsus<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><span style=\"font-weight: 400;\">common side effects of Rybelsus<\/span><span style=\"font-weight: 400;\"> are digestive system problems: nausea, <\/span><span style=\"font-weight: 400;\">stomach pain<\/span><span style=\"font-weight: 400;\">, and diarrhea. Based on <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=27f15fac-7d98-4114-a2ec-92494a91da98\"><span style=\"font-weight: 400;\">clinical trials<\/span><\/a><span style=\"font-weight: 400;\">, the most <\/span><span style=\"font-weight: 400;\">common side effects<\/span><span style=\"font-weight: 400;\"> in order are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Loss of appetite<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Constipation<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Other less commonly experienced <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> include:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal distension\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Belching\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gas\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Acid reflux or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/gerd-treatment-and-medications\"><span style=\"font-weight: 400;\">GERD<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/gastritis-treatment-and-medications\"><span style=\"font-weight: 400;\">Gastritis<\/span><\/a><\/li>\n<\/ul>\n<h2 id=\"serious-side-effects-of-rybelsus\"><span style=\"font-weight: 400;\">Serious side effects of Rybelsus<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/890805\/Rybelsus\/Adverse-Reactions\"><span style=\"font-weight: 400;\">serious side effects<\/span><\/a><span style=\"font-weight: 400;\"> of Rybelsus<\/span><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thyroid tumors<\/span><span style=\"font-weight: 400;\"> or cancer<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney damage<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Worsening of <\/span><span style=\"font-weight: 400;\">kidney failure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swollen <\/span><span style=\"font-weight: 400;\">pancreas<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swollen gallbladder<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gallstones<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetic retinopathy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Serious allergic reactions<\/span><\/li>\n<\/ul>\n<h3 id=\"rybelsus-and-weight-loss\"><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">weight loss<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Weight loss<\/span><span style=\"font-weight: 400;\"> is not listed as a <\/span><span style=\"font-weight: 400;\">side effect<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">. This is because weight loss is considered to be a benefit in the treatment of diabetes. <\/span><a href=\"https:\/\/www.rybelsus.com\/why-rybelsus\/rybelsus-results.html\"><span style=\"font-weight: 400;\">In a six-month study<\/span><\/a><span style=\"font-weight: 400;\">, people taking <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> lost an average of eight pounds. In a <\/span><a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2032183\"><span style=\"font-weight: 400;\">68-week study<\/span><\/a><span style=\"font-weight: 400;\"> of people receiving high-dose <\/span><span style=\"font-weight: 400;\">semaglutide<\/span><span style=\"font-weight: 400;\">, participants lost an average of 34 pounds, or 15% of their body weight. <\/span><span style=\"font-weight: 400;\">GLP-1<\/span><span style=\"font-weight: 400;\"> agonists like <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> slow down stomach emptying, so people don\u2019t need to eat as much to feel full. For this reason, drugs like <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/ozempic-0-25-or-0-5-mg-dose\/what-is\"><span style=\"font-weight: 400;\">Ozempic<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">metformin<\/span><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/victoza\"><span style=\"font-weight: 400;\">Victoza<\/span><\/a><span style=\"font-weight: 400;\"> are currently making headlines as <\/span><span style=\"font-weight: 400;\">weight loss<\/span><span style=\"font-weight: 400;\"> medications. However, changes in diet and exercise are an important component of losing weight with <\/span><span style=\"font-weight: 400;\">semaglutide<\/span><span style=\"font-weight: 400;\">, so it\u2019s less likely to happen without these changes. If weight goes down unintentionally while taking <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">, get nutritional or <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> from the prescriber.<\/span><\/p>\n<h3 id=\"rybelsus-and-vision-loss\"><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> and vision loss<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Semaglutide<\/span> <a href=\"https:\/\/www.pharmacytimes.com\/view\/semaglutide-carries-potential-risk-of-worsening-diabetic-retinopathy\"><span style=\"font-weight: 400;\">increases the risk<\/span><\/a><span style=\"font-weight: 400;\"> of worsening existing <\/span><span style=\"font-weight: 400;\">diabetic retinopathy<\/span><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/diabetic-retinopathy\/\"><span style=\"font-weight: 400;\">Diabetic retinopathy<\/span><\/a><span style=\"font-weight: 400;\"> is a disease of the blood vessels that provide oxygen and nutrients to the part of the eye responsible for vision. As a result, parts of the retina begin to die, and vision gets progressively worse. <\/span><span style=\"font-weight: 400;\">Semaglutide<\/span><span style=\"font-weight: 400;\"> seems to be more likely to cause retina problems than other <\/span><span style=\"font-weight: 400;\">GLP-1<\/span><span style=\"font-weight: 400;\"> agonists. No matter what drug is being taken, though, vision changes should always be immediately reported to the prescribing <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\t\t<div class=\"singlecare-dynamic-newsletter-wrapper sin-newsletter-wrapper\">\n\t\t\t<span class=\"heading\">Get our diabetes newsletter<\/span>\n\t\t\t<form class=\"form-wrapper\" data-newsletter-form=\"1\" data-subsource=\"Diabetes Newsletter\">\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<label for=\"dynamic-email\">Email<\/label>\n\t\t\t\t\t<input type=\"email\" id=\"dynamic-email\" class=\"email\" required>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"input-wrapper\">\n\t\t\t\t\t<input class=\"submit-form-btn\" type=\"submit\" value=\"Click to sign up\">\n\t\t\t\t<\/div>\n\t\t\t<\/form>\n\t\t\t<p class=\"success-message\" aria-live=\"polite\"><\/p>\n\t\t<\/div>\n\t<\/span><\/p>\n<h2 id=\"how-soon-do-rybelsus-side-effects-start\"><span style=\"font-weight: 400;\">How soon do <\/span><span style=\"font-weight: 400;\">Rybelsus side effects<\/span><span style=\"font-weight: 400;\"> start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Most of the mild <\/span><span style=\"font-weight: 400;\">side effects of Rybelsus<\/span> <a href=\"https:\/\/www.pdr.net\/drug-summary\/Rybelsus-semaglutide-24383\"><span style=\"font-weight: 400;\">begin early in treatment<\/span><\/a><span style=\"font-weight: 400;\">, particularly gastrointestinal complaints, such as <\/span><span style=\"font-weight: 400;\">stomach pain<\/span><span style=\"font-weight: 400;\">, nausea, diarrhea, and acid indigestion. However, a severe allergic reaction could happen quickly after taking the first dose. If this happens, seek medical attention immediately. More <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\"> will usually take some time to develop.<\/span><\/p>\n<h2 id=\"how-long-do-rybelsus-side-effects-last\"><span style=\"font-weight: 400;\">How long do <\/span><span style=\"font-weight: 400;\">Rybelsus side effects<\/span><span style=\"font-weight: 400;\"> last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some of the mild <\/span><span style=\"font-weight: 400;\">side effects of Rybelsus<\/span><span style=\"font-weight: 400;\"> may improve as the body adapts to the drug. If they don\u2019t, stopping the drug should improve them. Unfortunately, <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is a long-acting drug with a half-life of a week, so <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> could last two or more weeks after the last dose is taken.\u00a0<\/span><\/p>\n<h2 id=\"what-are-the-long-term-side-effects-of-rybelsus\"><span style=\"font-weight: 400;\">What are the long-term <\/span><span style=\"font-weight: 400;\">side effects of Rybelsus<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is intended for long-term therapy. No adverse effects specifically due to long-term use of <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> have been identified.<\/span><\/p>\n<h2 id=\"rybelsus-contraindications\"><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is never prescribed to people with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A personal or family history of <\/span><span style=\"font-weight: 400;\">medullary thyroid carcinoma<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">MTC<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Multiple endocrine neoplasia syndrome type<\/span><span style=\"font-weight: 400;\"> 2 (MEN2)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any history of an allergic reaction to <\/span><span style=\"font-weight: 400;\">semaglutide<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is inappropriate for people with <\/span><span style=\"font-weight: 400;\">Type 1 diabetes<\/span><span style=\"font-weight: 400;\"> or for those who suffer from <\/span><span style=\"font-weight: 400;\">diabetic ketoacidosis<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"pregnancy\"><span style=\"font-weight: 400;\">Pregnancy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">There is no evidence to determine if <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is safe to take during pregnancy. <\/span><span style=\"font-weight: 400;\">Animal studies<\/span><span style=\"font-weight: 400;\"> suggest it may cause birth defects or even the death of the fetus. Using <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> during pregnancy will be a decision that a woman and her <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> should make based on weighing its benefits and risks. Women who are attempting to get pregnant should stop taking <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> at least two months before the planned pregnancy. Others should use birth control.<\/span><\/p>\n<h3 id=\"breastfeeding\"><span style=\"font-weight: 400;\">Breastfeeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Healthcare providers<\/span><span style=\"font-weight: 400;\"> do not know if <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is present in human <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/alcohol-medications-when-breastfeeding\/\"><span style=\"font-weight: 400;\">breast milk<\/span><\/a><span style=\"font-weight: 400;\"> or if it affects a nursing infant. However, it is present in animal <\/span><span style=\"font-weight: 400;\">breast milk<\/span><span style=\"font-weight: 400;\"> and, theoretically, could cause problems in an infant. <\/span><span style=\"font-weight: 400;\">Healthcare providers<\/span><span style=\"font-weight: 400;\"> are advised to find other treatment options or ask the nursing mother to stop <\/span><span style=\"font-weight: 400;\">breastfeeding<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"children\"><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\"> has not approved <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> for use in anyone younger than 18 years of age.<\/span><\/p>\n<h3 id=\"seniors\"><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">In clinical trials, there was no difference in the effectiveness or <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> in people 65 years and older when compared to those younger than 65 years of age. However, seniors are more likely to experience <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/normal-blood-glucose-levels\/\"><span style=\"font-weight: 400;\">low blood sugar<\/span><\/a><span style=\"font-weight: 400;\"> in general, so <\/span><span style=\"font-weight: 400;\">healthcare providers<\/span><span style=\"font-weight: 400;\"> are advised to monitor them more carefully when prescribing any <\/span><span style=\"font-weight: 400;\">diabetes medication<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"rybelsus-warnings\"><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is very effective at controlling <\/span><span style=\"font-weight: 400;\">glucose<\/span><span style=\"font-weight: 400;\"> levels. It is not, however, free from problems, so prescribers may need to be cautious in certain situations.<\/span><\/p>\n<h3 id=\"black-box-warning\"><span style=\"font-weight: 400;\">Black box warning<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The <\/span><span style=\"font-weight: 400;\">FDA<\/span><span style=\"font-weight: 400;\"> has attached a <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/black-box-warning\/\"><span style=\"font-weight: 400;\">black box warning<\/span><\/a><span style=\"font-weight: 400;\"> to <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> about the risk of <\/span><span style=\"font-weight: 400;\">thyroid cancer<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is prohibited in people with a personal or family history of <\/span><span style=\"font-weight: 400;\">thyroid<\/span><span style=\"font-weight: 400;\"> C-cell tumors or those who have multiple endocrine neoplasia type 2, a hereditary condition that causes tumors on the <\/span><span style=\"font-weight: 400;\">thyroid<\/span><span style=\"font-weight: 400;\">, parathyroid, and adrenal glands.\u00a0<\/span><\/p>\n<h3 id=\"cautions\"><span style=\"font-weight: 400;\">Cautions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid some serious adverse effects caused by <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">healthcare providers<\/span><span style=\"font-weight: 400;\"> will use it cautiously in people with:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Symptoms of <\/span><span style=\"font-weight: 400;\">thyroid cancer<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney disease<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/pancreatitis-treatment-and-medications\"><span style=\"font-weight: 400;\">Pancreatitis<\/span><\/a><span style=\"font-weight: 400;\"> or a history of <\/span><span style=\"font-weight: 400;\">pancreatitis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetic retinopathy<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dehydration<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Because <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> may harm a fetus, <\/span><span style=\"font-weight: 400;\">healthcare providers<\/span><span style=\"font-weight: 400;\"> may advise women of reproductive age to use birth control when taking this drug.<\/span><\/p>\n<h3 id=\"abuse-and-dependence\"><span style=\"font-weight: 400;\">Abuse and dependence<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drug abuse, dependence, and withdrawal are not associated with <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"overdose\"><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Call a poison control center or get immediate medical treatment if an overdose is suspected. <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is typically prescribed in a 3 mg, 7 mg, or 14 <\/span><span style=\"font-weight: 400;\">mg dose<\/span><span style=\"font-weight: 400;\">.The most obvious symptoms of an overdose are nausea and vomiting, but the most concerning symptom is <\/span><span style=\"font-weight: 400;\">low blood sugar<\/span><span style=\"font-weight: 400;\">. Observation may be required for several days after an overdose because of the medication\u2019s long half-life.<\/span><\/p>\n<h2 id=\"rybelsus-interactions\"><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> has an extremely large number of possible <\/span><span style=\"font-weight: 400;\">drug interactions<\/span><span style=\"font-weight: 400;\">, though most have not been studied. First, <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> slows down stomach emptying, so other medications may stay in the stomach longer. In many cases, this means that people will have slower eliminations of other oral medicines that they take, making <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> more likely. <\/span><span style=\"font-weight: 400;\">Healthcare providers<\/span><span style=\"font-weight: 400;\"> are urged to get a full medication list, including over-the-counter (OTC) medications, and advise people of possible side effect risks with other <\/span><span style=\"font-weight: 400;\">oral medications<\/span><span style=\"font-weight: 400;\">. It is important to make sure to take <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> as instructed. It should be taken on an empty stomach, 30 minutes before any other food or medications.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Many drugs affect <\/span><span style=\"font-weight: 400;\">glucose<\/span><span style=\"font-weight: 400;\"> levels in the blood, such as salicylates (<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aspirin\"><span style=\"font-weight: 400;\">aspirin<\/span><\/a><span style=\"font-weight: 400;\">), <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">corticosteroids<\/span><\/a><span style=\"font-weight: 400;\">, some types of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">blood pressure<\/span><\/a><span style=\"font-weight: 400;\"> drugs, and many more. These reduce the effectiveness of diabetes drugs, including <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">Healthcare providers<\/span><span style=\"font-weight: 400;\"> should be aware of these drugs and they may have to perform more blood sugar tests to make sure there isn\u2019t a problem.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finally, <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> is more likely to cause <\/span><span style=\"font-weight: 400;\">low blood sugar<\/span><span style=\"font-weight: 400;\"> in people who are also taking drugs that, like <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">, increase the body\u2019s production of insulin. These drugs are called insulin secretagogues and include <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/sulfonylureas\"><span style=\"font-weight: 400;\">sulfonylureas<\/span><\/a><span style=\"font-weight: 400;\">, like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/glipizide\"><span style=\"font-weight: 400;\">glipizide<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/meglitinides\"><span style=\"font-weight: 400;\">meglitinides<\/span><\/a><span style=\"font-weight: 400;\">, like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/repaglinide\"><span style=\"font-weight: 400;\">repaglinide<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h2 id=\"how-to-avoid-rybelsus-side-effects\"><span style=\"font-weight: 400;\">How to avoid <\/span><span style=\"font-weight: 400;\">Rybelsus side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Rybelsus side effects<\/span><span style=\"font-weight: 400;\"> are fairly minor, but most involve digestive system troubles. Even these, however, can be avoided. More importantly, a few simple measures can reduce the risk of <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"1-give-the-prescriber-a-complete-medical-history\"><span style=\"font-weight: 400;\">1. Give the prescriber a complete medical history<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To help prevent <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\">, the prescriber will need to not only know all current <\/span><span style=\"font-weight: 400;\">medical conditions,<\/span><span style=\"font-weight: 400;\"> but also a history of some conditions, including those in family members. <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=27f15fac-7d98-4114-a2ec-92494a91da98\"><span style=\"font-weight: 400;\">Make sure to tell the prescriber about<\/span><\/a><span style=\"font-weight: 400;\">:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any personal or family history of <\/span><span style=\"font-weight: 400;\">thyroid cancer<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pancreas<\/span><span style=\"font-weight: 400;\"> problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gallbladder problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Eye problems associated with diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy or plans to become pregnant<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breastfeeding<\/span><span style=\"font-weight: 400;\"> or plans to <\/span><span style=\"font-weight: 400;\">breastfeed<\/span><\/li>\n<\/ul>\n<h3 id=\"2-share-a-complete-list-of-drugs-being-taken-with-the-prescriber\"><span style=\"font-weight: 400;\">2. Share a complete list of drugs being taken with the prescriber<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drug interactions<\/span><span style=\"font-weight: 400;\"> are another potential source of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\">, so make sure the prescriber has a complete picture of all <\/span><span style=\"font-weight: 400;\">prescription drugs<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">OTC<\/span><span style=\"font-weight: 400;\"> medications, and <\/span><span style=\"font-weight: 400;\">supplements<\/span><span style=\"font-weight: 400;\"> being taken.<\/span><\/p>\n<h3 id=\"3-take-rybelsus-as-directed\"><span style=\"font-weight: 400;\">3. Take <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> as directed<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Another sure way to avoid <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> is to simply follow the directions when taking <\/span><span style=\"font-weight: 400;\">doses of Rybelsus<\/span><span style=\"font-weight: 400;\">. Take it on an <\/span><span style=\"font-weight: 400;\">empty stomach<\/span><span style=\"font-weight: 400;\"> when first waking up. Do not eat anything or take any other medications for 30 minutes. Swallow the <\/span><span style=\"font-weight: 400;\">tablet whole, making sure not to<\/span><span style=\"font-weight: 400;\"> crush or chew it. Do not take it with more than four ounces of water.\u00a0<\/span><\/p>\n<h3 id=\"4-do-not-take-a-missed-dose\"><span style=\"font-weight: 400;\">4. Do not take a <\/span><span style=\"font-weight: 400;\">missed dose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">It\u2019s important not to take too much <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> because it lasts in the body for several weeks. If a dose is missed, do not take the <\/span><span style=\"font-weight: 400;\">missed dose if it has been more than 12 hours since the time it was supposed to be taken<\/span><span style=\"font-weight: 400;\">. Take the next dose as scheduled.<\/span><\/p>\n<h3 id=\"5-read-the-medication-guide\"><span style=\"font-weight: 400;\">5. Read the <\/span><span style=\"font-weight: 400;\">medication guide<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Before taking the first <\/span><span style=\"font-weight: 400;\">dose of Rybelsus<\/span><span style=\"font-weight: 400;\">, read the <\/span><span style=\"font-weight: 400;\">drug information<\/span><span style=\"font-weight: 400;\"> included in the <\/span><span style=\"font-weight: 400;\">medication guide<\/span><span style=\"font-weight: 400;\"> in order to become familiar with the <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> and what to do in case problems arise.<\/span><\/p>\n<h3 id=\"6-eat-modestly\"><span style=\"font-weight: 400;\">6. Eat modestly<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Nausea is the most common complaint in people taking <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">. Meal size may need to be reduced. If nausea is a problem, eat plain foods in small amounts. Avoid lying down after eating.<\/span><\/p>\n<h3 id=\"7-eat-healthily\"><span style=\"font-weight: 400;\">7. Eat healthily<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To help prevent gallbladder problems, eat smaller meals several times per day. Try to remove fat from the diet while still eating <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/diabetes-diet\/\"><span style=\"font-weight: 400;\">foods that are appropriate for diabetes<\/span><\/a><span style=\"font-weight: 400;\">. Fatty fish is okay, but try to eat lean meat.<\/span><\/p>\n<h3 id=\"8-regularly-check-blood-sugar-levels\"><span style=\"font-weight: 400;\">8. Regularly check <\/span><span style=\"font-weight: 400;\">blood sugar levels<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid <\/span><span style=\"font-weight: 400;\">hypoglycemia<\/span><span style=\"font-weight: 400;\">, regularly check <\/span><span style=\"font-weight: 400;\">blood sugar levels<\/span><span style=\"font-weight: 400;\">, especially if <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/insulins\"><span style=\"font-weight: 400;\">insulin<\/span><\/a><span style=\"font-weight: 400;\"> or other drugs that <\/span><span style=\"font-weight: 400;\">lower blood sugar<\/span><span style=\"font-weight: 400;\"> are being taken.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects-of-rybelsus\"><span style=\"font-weight: 400;\">How to treat <\/span><span style=\"font-weight: 400;\">side effects of Rybelsus<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">As with many drugs, the mild <\/span><span style=\"font-weight: 400;\">side effects of Rybelsus<\/span><span style=\"font-weight: 400;\"> can be handled at home unless they get severe. In severe cases\u2014or in cases with <\/span><span style=\"font-weight: 400;\">serious side effects<\/span><span style=\"font-weight: 400;\">\u2014medical help may be needed.<\/span><\/p>\n<h3 id=\"nausea-and-vomiting\"><span style=\"font-weight: 400;\">Nausea and vomiting<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If nausea or vomiting occurs, drink plenty of fluids in small sips to avoid dehydration. If vomiting is severe or doesn\u2019t go away, get medical help.<\/span><\/p>\n<h3 id=\"headaches\"><span style=\"font-weight: 400;\">Headaches<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drinking fluids and resting can help with a headache. Get <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> from the prescriber before using <\/span><span style=\"font-weight: 400;\">OTC<\/span><span style=\"font-weight: 400;\"> pain relievers. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/acetaminophen\"><span style=\"font-weight: 400;\">Acetaminophen<\/span><\/a><span style=\"font-weight: 400;\"> may be okay, but <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/aspirin\/what-is\"><span style=\"font-weight: 400;\">aspirin<\/span><\/a><span style=\"font-weight: 400;\"> could raise blood sugar a bit. If headaches are very bad or don\u2019t go away, inform the prescribing <\/span><span style=\"font-weight: 400;\">healthcare professional<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span><\/p>\n<h3 id=\"vision-problems\"><span style=\"font-weight: 400;\">Vision problems<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Immediately contact the prescriber if vision changes or deteriorates.<\/span><\/p>\n<h3 id=\"low-blood-sugar\"><span style=\"font-weight: 400;\">Low blood sugar<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If blood sugar gets too low, follow the instructions given by the prescriber. These instructions may include drinking juice, taking <\/span><span style=\"font-weight: 400;\">glucose<\/span><span style=\"font-weight: 400;\"> tablets, or eating sugary candy. <\/span><span style=\"font-weight: 400;\">Symptoms of low blood sugar<\/span><span style=\"font-weight: 400;\"> include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lightheadedness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Confusion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blurred vision<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast heartbeat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood changes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Jitteriness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Feeling hungry<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakness<\/span><\/li>\n<\/ul>\n<h3 id=\"pancreatitis\"><span style=\"font-weight: 400;\">Pancreatitis<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">A swollen <\/span><span style=\"font-weight: 400;\">pancreas<\/span><span style=\"font-weight: 400;\"> is a <\/span><span style=\"font-weight: 400;\">possible side effect<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\">. Immediately report any severe abdominal pain to the prescriber. Nausea is another possible symptom.<\/span><\/p>\n<h3 id=\"gallbladder-problems\"><span style=\"font-weight: 400;\">Gallbladder problems<\/span><\/h3>\n<p><a href=\"https:\/\/www.singlecare.com\/conditions\/gallstones-treatment-and-medications\"><span style=\"font-weight: 400;\">Gallstones<\/span><\/a><span style=\"font-weight: 400;\"> and gall bladder swelling are <\/span><span style=\"font-weight: 400;\">possible side effects of Rybelsus<\/span><span style=\"font-weight: 400;\">. They are both serious problems, so any symptoms of gallbladder problems should be immediately reported to the prescriber. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fever<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pale stools<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yellowing of the skin or eyes<\/span><\/li>\n<\/ul>\n<h3 id=\"thyroid-problems\"><span style=\"font-weight: 400;\">Thyroid<\/span><span style=\"font-weight: 400;\"> problems<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Immediately contact the prescriber if signs of a <\/span><span style=\"font-weight: 400;\">thyroid tumor<\/span><span style=\"font-weight: 400;\"> are noticed, such as:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A lump or swelling in the neck<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shortness of breath<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble swallowing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hoarseness<\/span><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<\/ul>\n<h3 id=\"kidney-problems\"><span style=\"font-weight: 400;\">Kidney problems<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Rybelsus<\/span><span style=\"font-weight: 400;\"> can cause kidney function to deteriorate, so contact the prescribing <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> if any of these symptoms of <\/span><span style=\"font-weight: 400;\">kidney problems<\/span><span style=\"font-weight: 400;\"> are noticed:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Urinating less frequently<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decreased urine levels<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tiredness<\/span><\/li>\n<\/ul>\n<h3 id=\"allergic-reactions\"><span style=\"font-weight: 400;\">Allergic reactions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Stop taking the medicine and get medical help at any sign of an allergic reaction, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Swelling of the face, mouth, lips, or throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Trouble breathing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Itching<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hives<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fast heartbeat<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Rybelsus is a brand-name prescription drug that, along with diet and exercise, helps to control high blood sugar in people with Type 2 diabetes mellitus. Its active ingredient, semaglutide, belongs to a family of diabetes drugs called glucagon-like peptide-1 receptor agonists, known as GLP-1 agonists. These drugs increase the body\u2019s production of insulin and decrease [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":54854,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10298,21067,12752],"coauthors":[8861],"class_list":["post-54851","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-diabetes","tag-glp-1-drugs","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Rybelsus side effects and safety precautions you should know<\/title>\n<meta name=\"description\" content=\"Learn how Rybelsus, a GLP-1 agonist for Type 2 diabetes, helps manage blood sugar levels, potential side effects, and safety precautions. Understand who should avoid using Rybelsus and how it compares to other treatments.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/rybelsus-side-effects\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Rybelsus side effects and how to avoid them\" \/>\n<meta property=\"og:description\" content=\"Learn how Rybelsus, a GLP-1 agonist for Type 2 diabetes, helps manage blood sugar levels, potential side effects, and safety precautions. 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