{"id":54868,"date":"2022-10-28T09:00:24","date_gmt":"2022-10-28T13:00:24","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=54868"},"modified":"2026-01-23T11:24:32","modified_gmt":"2026-01-23T16:24:32","slug":"budesonide-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/budesonide-side-effects\/","title":{"rendered":"Budesonide side effects and how to avoid them"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/budesonide\"><span style=\"font-weight: 400;\">Budesonide<\/span><\/a><span style=\"font-weight: 400;\"> is a generic prescription <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">corticosteroid<\/span><\/a><span style=\"font-weight: 400;\">. As a pill, budesonide is used to treat <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/crohns-disease-treatment-and-medications\"><span style=\"font-weight: 400;\">Crohn\u2019s disease<\/span><\/a><span style=\"font-weight: 400;\"> or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/ulcerative-colitis-treatment-and-medications\"><span style=\"font-weight: 400;\">ulcerative colitis<\/span><\/a><span style=\"font-weight: 400;\">. Rectal foam is an alternative to pills for people with ulcerative colitis located near the anus. Budesonide inhalant provides <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/asthma-treatment-and-medications\"><span style=\"font-weight: 400;\">asthma<\/span><\/a><span style=\"font-weight: 400;\"> maintenance treatment for young children, helping to reduce the frequency and severity of asthma attacks. Budesonide is frequently combined with other medications in a single inhaler to help keep airways open in adults with asthma, emphysema, or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/bronchitis-treatment-and-medications\"><span style=\"font-weight: 400;\">chronic bronchitis<\/span><\/a><span style=\"font-weight: 400;\">. Finally, as a prescription or over-the-counter nasal spray, budesonide helps relieve nasal symptoms of seasonal allergies such as runny nose. For some, budesonide can be prescribed in a brand-name version like <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/uceris\"><span style=\"font-weight: 400;\">Uceris<\/span><\/a><span style=\"font-weight: 400;\"> (tablet or rectal foam), <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/pulmicort\"><span style=\"font-weight: 400;\">Pulmicort<\/span><\/a><span style=\"font-weight: 400;\"> (inhalant), or Rhinocort (nasal spray). As a corticosteroid, budesonide reduces swelling in the colon, lungs, or nose by blocking the immune system. It has many of the standard side effects typical of corticosteroids, though budesonide inhalants, nasal spray, or rectal foam are less likely to cause problems.<\/span><\/p>\n<p><span data-sheets-root=\"1\" data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:6849,&quot;3&quot;:{&quot;1&quot;:0},&quot;9&quot;:1,&quot;10&quot;:2,&quot;12&quot;:0,&quot;14&quot;:{&quot;1&quot;:2,&quot;2&quot;:0},&quot;15&quot;:&quot;Arial&quot;}\" data-sheets-formula=\"=CONCATENATE(R[0]C[-2],R[0]C[-3],R[0]C[-1])\"><\/span><\/p>\n<h2 id=\"common-side-effects-of-budesonide\"><span style=\"font-weight: 400;\">Common side effects of budesonide<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Based on <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=0659420e-e376-4b90-98bf-71af41c18676\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">clinical trials<\/span><\/a><span style=\"font-weight: 400;\">, the most common side effect of <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/budesonide\/what-is\"><span style=\"font-weight: 400;\">budesonide<\/span><\/a><span style=\"font-weight: 400;\"> capsules or tablets is headache followed by:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Respiratory infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypercorticism (Cushing syndrome)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Back pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Indigestion<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dizziness<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Flatulence<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fatigue<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Abdominal distension<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mood changes<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Since inhaled budesonide is applied topically to the lung\u2019s surface, less budesonide enters the bloodstream than when taken as a pill. Side effects, then, are less commonly experienced. The <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=e8ef9489-83a2-4817-b21c-ea3fecd8c8dd\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">most common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of inhaled budesonide are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Respiratory infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stuffy nose<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ear infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coughing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Viral infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Digestive system problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Yeast infection (oral thrush)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Conjunctivitis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skin rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Budesonide nasal spray is also less likely to cause side effects which mainly affect the nose, sinuses, and throat. The <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=32a7d4c3-6192-956d-a4e9-e38d309fac2a\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">most common side effects<\/span><\/a><span style=\"font-weight: 400;\"> of budesonide nasal spray are:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nosebleed<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sore throat<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Airway closure (bronchospasm)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Coughing<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal irritation<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Budesonide aerosol rectal foam is also a topical treatment. In this case, it is applied topically to the first 15 inches or so of the colon near the rectum. The most common side effect is a drop in the body\u2019s cortisol levels. The only other significant side effects are suppression of the adrenal gland (adrenal insufficiency) and nausea.<\/span><\/p>\n<h2 id=\"serious-side-effects-of-budesonide\"><span style=\"font-weight: 400;\">Serious side effects of budesonide<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The most <\/span><a href=\"https:\/\/online.epocrates.com\/drugs\/259905\/budesonide\/Adverse-Reactions\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">serious side effects<\/span><\/a><span style=\"font-weight: 400;\"> of oral budesonide include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High fluid pressure in the brain (intracranial hypertension)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood sugar\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal obstruction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suppression of the adrenal gland<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypercorticism (Cushing syndrome)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Suppression of the immune system<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma (high pressure in the eye)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cataracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Growth suppression of children<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Withdrawal symptoms<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reaction<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The most serious side effects of inhaled budesonide include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Psychiatric disorders<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypercorticism<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cataracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Growth suppression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The most serious side effects of budesonide nasal spray include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cataracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Growth suppression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions<\/span><\/li>\n<\/ul>\n<h3 id=\"budesonide-and-hypercorticism\"><span style=\"font-weight: 400;\">Budesonide and hypercorticism<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The most common side effect of the chronic use of budesonide is hypercorticism, also called <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/cushing-syndrome-treatment-and-medications\"><span style=\"font-weight: 400;\">Cushing syndrome<\/span><\/a><span style=\"font-weight: 400;\">. Steroids like budesonide imitate a hormone in the body called cortisol. Hypercorticism simply means \u201ctoo much cortisol.\u201d The incidence is highest in people taking budesonide orally since more of the drug enters the bloodstream. However, even when taken as an inhalant or nasal spray, some budesonide does get into the bloodstream. Over time, the excess corticosteroids\u2014too much cortisol, that is\u2014change the body and the way it works. These changes include acne, easy bruising, swollen face (or \u201cmoon face\u201d), unwanted hair growth, stretch marks, and fat buildup at the back of the neck (buffalo hump). Weight gain and muscle weakness can also result from the prolonged use of corticosteroids. Most of these effects will improve once the corticosteroid treatment ends, but some could be long-lasting.<\/span><\/p>\n<h2 id=\"how-soon-do-budesonide-side-effects-start\"><span style=\"font-weight: 400;\">How soon do budesonide side effects start?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Many of the most common side effects of budesonide start early in treatment, sometimes after the first dose. These include headache, dizziness, digestive system problems, and mood changes. Some of the most serious side effects are delayed side effects, but an allergic reaction can happen within minutes of the first dose. Many serious side effects, however, are due to the prolonged use of budesonide or other steroids.\u00a0<\/span><\/p>\n<h2 id=\"how-long-do-budesonide-side-effects-last\"><span style=\"font-weight: 400;\">How long do budesonide side effects last?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Mild side effects might improve over time, but it\u2019s not guaranteed. Some will last as long as the drug is taken. Others, such as loss of bone density, weight gain, acne, cataracts, and glaucoma could worsen the longer budesonide is taken. Additionally, infections due to immune suppression may keep happening over and over again as long as the drug is being taken.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Most side effects will improve when budesonide is discontinued. It takes a while, however, to stop taking budesonide. To prevent withdrawal, a steadily decreasing dose must be taken over several weeks. By the time the tapering is finished, many mild side effects will have gotten better. Some more serious side effects, like cataracts or osteoporosis, are longer-term problems that may require medical treatment.<\/span><\/p>\n<h2 id=\"what-are-the-long-term-side-effects-of-budesonide\"><span style=\"font-weight: 400;\">What are the long-term side effects of budesonide?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Some of the most serious side effects of budesonide result from prolonged use of budesonide or other corticosteroids. These include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hypercorticism<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Adrenal gland dysfunction<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Immune system suppression<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cataracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/osteoporosis-treatment-and-medications\"><span style=\"font-weight: 400;\">Osteoporosis<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Growth suppression<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">People taking budesonide as a maintenance or long-term treatment for irritable bowel disease (IBD), asthma, or <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/copd-treatment-and-medications\"><span style=\"font-weight: 400;\">COPD<\/span><\/a><span style=\"font-weight: 400;\">, should discuss the long-term consequences with the prescriber.<\/span><\/p>\n<h2 id=\"budesonide-contraindications\"><span style=\"font-weight: 400;\">Budesonide contraindications<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Oral budesonide can never be taken by people with severe liver disease or allergies to budesonide or other corticosteroids.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Budesonide inhalants or nasal sprays are also never prescribed to people with budesonide or corticosteroid allergies. It is not appropriate to use budesonide inhalers to treat an asthma attack.<\/span><\/p>\n<h3 id=\"pregnancy\"><span style=\"font-weight: 400;\">Pregnancy<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">When taken as a tablet or capsule during pregnancy, budesonide could cause birth defects or worse, especially during the first trimester. Oral budesonide is not prohibited during pregnancy, but the risks to the fetus will have to be weighed against the benefits of taking the drug.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There is not enough information to determine if inhaled budesonide or nasal spray is safe to take during pregnancy. Again, risks and benefits will have to be weighed against each other.<\/span><\/p>\n<h3 id=\"breastfeeding\"><span style=\"font-weight: 400;\">Breastfeeding<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Budesonide is present in human breast milk but in small amounts. Healthcare professionals consider oral, inhaled, and nasal budesonide to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK501215\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">be acceptably safe<\/span><\/a><span style=\"font-weight: 400;\"> in breastfeeding mothers.<\/span><\/p>\n<h3 id=\"children\"><span style=\"font-weight: 400;\">Children<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Inhaled budesonide is FDA approved for use in children from the ages of 12 months to 8 years old. However, individual brand-name products may be approved for different age ranges. Budesonide capsules and tablets can be taken by children as young as 8 years old. The nasal spray can be used by children as young as 6 years old. The biggest worry is the effects of oral, inhaled, or nasal budesonide on a child\u2019s growth, particularly when used for a prolonged time. Growth\u2014both height and weight\u2014should be monitored carefully when a child is taking budesonide.<\/span><\/p>\n<h3 id=\"seniors\"><span style=\"font-weight: 400;\">Seniors<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Dosage reductions are not required in people older than 65. However, healthcare providers will try to start with lower doses.\u00a0<\/span><\/p>\n<h2 id=\"budesonide-warnings\"><span style=\"font-weight: 400;\">Budesonide warnings<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">All corticosteroids can cause problems due to pre-existing conditions, overuse, or overdose. Budesonide is no exception, though it\u2019s generally less worrisome when taken as an inhalant or nasal spray.<\/span><\/p>\n<h3 id=\"cautions\"><span style=\"font-weight: 400;\">Cautions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Many of budesonide\u2019s side effects can exacerbate existing medical conditions. Budesonide isn\u2019t necessarily prohibited, but it may require dose adjustments or careful monitoring by a healthcare professional. These conditions include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Weakened immune system<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/diabetes-treatment-and-medications\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/a><span style=\"font-weight: 400;\"> (or a family history of diabetes)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/blood-pressure-treatment-and-medications\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High pressure in the eye<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High fluid pressure in the skull<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Active infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Active chickenpox, shingles, or measles infections or exposure to measles or varicella<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A past <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/tuberculosis-treatment-and-medications\"><span style=\"font-weight: 400;\">tuberculosis<\/span><\/a><span style=\"font-weight: 400;\"> infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Malnutrition<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cataracts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/glaucoma-treatment-and-medications\"><span style=\"font-weight: 400;\">Glaucoma<\/span><\/a><span style=\"font-weight: 400;\"> (or a family history of glaucoma)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gastrointestinal perforation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/ulcer-treatment-and-medications\"><span style=\"font-weight: 400;\">Ulcers<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nasal trauma, surgery, sores, or perforation<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/myasthenia-gravis-treatment-and-medications\"><span style=\"font-weight: 400;\">Myasthenia gravis<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/epilepsy-treatment-and-medications\"><span style=\"font-weight: 400;\">Seizure disorders<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cushing\u2019s syndrome<\/span><\/li>\n<\/ul>\n<h3 id=\"abuse\"><span style=\"font-weight: 400;\">Abuse<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Budesonide is not associated with drug abuse.\u00a0<\/span><\/p>\n<h3 id=\"dependence-and-withdrawal\"><span style=\"font-weight: 400;\">Dependence and withdrawal<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Like all corticosteroids, budesonide reduces or suppresses the body\u2019s natural production of the hormone cortisol. This disrupts an entire complex of hormone production in the body. For this reason, the sudden discontinuation of budesonide or any other corticosteroid can produce unpleasant side effects like tiredness, weakness, muscle pain, nausea, headaches, dizziness, blurred vision, loss of appetite, weight loss, and other problems. When it\u2019s time to stop taking budesonide, the doses should be tapered gradually.<\/span><\/p>\n<h3 id=\"overdose\"><span style=\"font-weight: 400;\">Overdose<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">If too much budesonide is taken at one time, call a poison control center or get medical attention.\u00a0<\/span><\/p>\n<h2 id=\"budesonide-interactions\"><span style=\"font-weight: 400;\">Budesonide interactions<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Budesonide has many different and powerful effects on the body, so it interacts with a number of prescription drugs, over-the-counter medications, and even dietary supplements. The list is very long, but the most important are:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Live vaccines. <\/b><span style=\"font-weight: 400;\">Budesonide is prohibited in anyone getting a live vaccine. Budesonide suppresses the immune systems, so vaccines containing weakened bacteria or viruses could potentially blow up into active and life-threatening infections.<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Vaccines. <\/b><span style=\"font-weight: 400;\">Other vaccines are safe, but because budesonide weakens the immune system, they\u2019re less effective.<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Immune suppressants.<\/b><span style=\"font-weight: 400;\"> Combining budesonide with immune suppressants weakens the immune system even further, leaving people more vulnerable to infections.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Other corticosteroids.<\/b><span style=\"font-weight: 400;\"> Taking more than one corticosteroid increases the risk for side effects, particularly adrenal gland problems.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Drugs and foods that block the body\u2019s metabolism of budesonide. <\/b><span style=\"font-weight: 400;\">Some substances tie up the liver enzyme that breaks down budesonide. As a result, budesonide builds up in the blood, increasing the risk for side effects. Healthcare providers are aware of these drugs and will adjust doses accordingly. Grapefruit and grapefruit juice are also in this category, so they should be avoided when taking budesonide.<\/span><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Desmopressin. <\/b><span style=\"font-weight: 400;\">Used to treat frequent urination or bedwetting, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/desmopressin-acetate\"><span style=\"font-weight: 400;\">desmopressin<\/span><\/a><span style=\"font-weight: 400;\"> should never be combined with budesonide because of the risk of low blood sodium. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/mifepristone\"><span style=\"font-weight: 400;\">Mifepristone<\/span><\/a><span style=\"font-weight: 400;\"> is also contraindicated in anyone taking budesonide.<\/span><\/li>\n<\/ul>\n<h2 id=\"how-to-avoid-budesonide-side-effects\"><span style=\"font-weight: 400;\">How to avoid budesonide side effects<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Adverse effects are a fact of life when taking corticosteroids, but they\u2019re not entirely unavoidable. Here are a few tips to keep budesonide side effects at arm\u2019s length.\u00a0<\/span><\/p>\n<h3 id=\"1-follow-instructions\"><span style=\"font-weight: 400;\">1. Follow instructions<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The first and best rule is to take budesonide exactly as instructed. Don\u2019t take too much. Don\u2019t take doses too frequently. If taking over-the-counter nasal spray, read the drug information carefully and follow all its directions.<\/span><\/p>\n<h3 id=\"2-tell-the-prescriber-about-all-medical-conditions-and-medications\"><span style=\"font-weight: 400;\">2. Tell the prescriber about all medical conditions and medications<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Some of budesonide\u2019s most serious side effects involve making existing medical conditions worse. The prescriber should have a complete medical history that includes:\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any active infection<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Any past infection with tuberculosis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Exposure to measles or chickenpox<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A weakened immune system<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach ulcers<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High blood pressure<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diabetes<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thyroid problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Osteoporosis or low bone mineral density<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Myasthenia gravis<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Liver problems<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pregnancy or pregnancy plans<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breastfeeding or any plans to breastfeed<\/span><\/li>\n<\/ul>\n<h3 id=\"3-tell-the-prescriber-about-all-medications-being-taken\"><span style=\"font-weight: 400;\">3. Tell the prescriber about all medications being taken<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drug interactions are another common source of trouble when taking budesonide, so make sure the prescriber has a complete picture of all drugs and supplements being taken. When seeing any other healthcare provider, tell them about budesonide before they prescribe another drug.<\/span><\/p>\n<h3 id=\"4-avoid-grapefruit-and-grapefruit-juice\"><span style=\"font-weight: 400;\">4. Avoid grapefruit and grapefruit juice<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Do not eat grapefruits or drink grapefruit juice throughout the duration of budesonide treatment. Grapefruit could increase the risk and severity of budesonide side effects.<\/span><\/p>\n<h3 id=\"5-take-calcium-and-vitamin-d-supplements\"><span style=\"font-weight: 400;\">5. Take calcium and vitamin D supplements<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid bone loss during prolonged budesonide treatment, take calcium and vitamin D supplements or eat foods rich in these two bone-healthy nutrients.<\/span><\/p>\n<h3 id=\"6-avoid-infections\"><span style=\"font-weight: 400;\">6. Avoid infections<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Because budesonide weakens the immune system, take precautions to avoid getting an infection. Try to avoid people who are sick. Wear a face covering and keep your distance when in public.<\/span><\/p>\n<h3 id=\"7-rinse-out-the-mouth-after-taking-a-puff-of-budesonide-inhalant\"><span style=\"font-weight: 400;\">7. Rinse out the mouth after taking a puff of budesonide inhalant<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To prevent yeast infections of the mouth, rinse out the mouth with water and spit it out shortly after taking a puff of budesonide.\u00a0<\/span><\/p>\n<h3 id=\"8-do-not-stop-taking-budesonide\"><span style=\"font-weight: 400;\">8. Do not stop taking budesonide<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To avoid withdrawal symptoms, do not stop taking budesonide until talking to the prescriber.<\/span><\/p>\n<h2 id=\"how-to-treat-side-effects-of-budesonide\"><span style=\"font-weight: 400;\">How to treat side effects of budesonide<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If they do happen, some side effects can be handled at home. Others, however, may require medical attention.<\/span><\/p>\n<h3 id=\"infection\"><span style=\"font-weight: 400;\">Infection<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Contact the prescriber if signs of an infection are noticed. It may be nothing, but because budesonide weakens the immune system, a healthcare professional should be aware of the infection.<\/span><\/p>\n<h3 id=\"digestive-system-problems\"><span style=\"font-weight: 400;\">Digestive system problems<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Contact the prescriber if there\u2019s any evidence of gastrointestinal problems such as stomach pain, black and tarry stools, bloody stools, vomiting, or blood in the vomit.<\/span><\/p>\n<h3 id=\"hypercorticism\"><span style=\"font-weight: 400;\">Hypercorticism<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Tell the prescribing healthcare provider if problems emerge due to taking too much budesonide for too long including acne, unwanted hair growth, changes in the face\u2019s shape, unexplained stretch marks on the skin, and easy bruising. The prescriber may need to adjust the dose.<\/span><\/p>\n<h2 id=\"sources\"><span style=\"font-weight: 400;\">Sources<\/span><\/h2>\n<ul>\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK501215\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide<\/span><\/a><span style=\"font-weight: 400;\">, Drugs and Lactation Database<\/span><\/li>\n<li><a href=\"https:\/\/online.epocrates.com\/drugs\/259901\/budesonide\/Adult-Dosing\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide<\/span><\/a><span style=\"font-weight: 400;\">, Epocrates<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=2c2ce3a8-7125-4ee0-afae-73a9cac8fd31\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide capsule prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/www.pdr.net\/drug-summary\/Uceris-Rectal-Foam-budesonide-3646\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide drug summary<\/span><\/a><span style=\"font-weight: 400;\">, Prescriber\u2019s Digital Reference<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=e8ef9489-83a2-4817-b21c-ea3fecd8c8dd\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide inhalation prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/online.epocrates.com\/drugs\/115701\/budesonide-inhaled\/Adult-Dosing\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide inhaled<\/span><\/a><span style=\"font-weight: 400;\">, Epocrates\u00a0<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=32a7d4c3-6192-956d-a4e9-e38d309fac2a\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Budesonide nasal prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<li><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=230e4596-2a9b-4d55-b0a0-0cabbcff5289\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Uceris budesonide aerosol foam prescribing information<\/span><\/a><span style=\"font-weight: 400;\">, U.S. National Library of Medicine<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Budesonide is a generic prescription corticosteroid. As a pill, budesonide is used to treat Crohn\u2019s disease or ulcerative colitis. Rectal foam is an alternative to pills for people with ulcerative colitis located near the anus. Budesonide inhalant provides asthma maintenance treatment for young children, helping to reduce the frequency and severity of asthma attacks. Budesonide [&hellip;]<\/p>\n","protected":false},"author":15,"featured_media":54870,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[790,12752],"coauthors":[8861],"class_list":["post-54868","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-chronic-disease","tag-medication-side-effects","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Budesonide side effects and how to avoid them | SingleCare<\/title>\n<meta name=\"description\" content=\"Hypercorticism is a common budesonide side effect. 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