{"id":54920,"date":"2022-11-04T23:02:02","date_gmt":"2022-11-05T03:02:02","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=54920"},"modified":"2024-10-25T11:04:04","modified_gmt":"2024-10-25T15:04:04","slug":"olanzapine-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/olanzapine-alternatives\/","title":{"rendered":"Olanzapine alternatives: What can I take instead of olanzapine?"},"content":{"rendered":"<p><a href=\"https:\/\/www.singlecare.com\/prescription\/olanzapine\/what-is\"><span style=\"font-weight: 400;\">Olanzapine<\/span><\/a><span style=\"font-weight: 400;\"> may serve as a pivotal piece of your <\/span><span style=\"font-weight: 400;\">mental health<\/span><span style=\"font-weight: 400;\"> maintenance. By influencing the action of brain neurotransmitters, namely <\/span><span style=\"font-weight: 400;\">dopamine<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">serotonin<\/span><span style=\"font-weight: 400;\">, it can halt <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/schizophrenia-treatment-and-medications\"><span style=\"font-weight: 400;\">schizophrenia<\/span><span style=\"font-weight: 400;\">&rsquo;s <\/span><span style=\"font-weight: 400;\">psychotic symptoms<\/span><\/a><span style=\"font-weight: 400;\">, like hallucinations, paranoia, and delusions, and <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/bipolar-disorder-treatment-and-medications\"><span style=\"font-weight: 400;\">bipolar disorder<\/span><span style=\"font-weight: 400;\">&rsquo;s manic and depressive symptoms<\/span><\/a><span style=\"font-weight: 400;\">. Thereafter, <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> is often continued long-term for prevention of these problems. Your enthusiasm for its extensive benefits may be justifiably tempered by experiences with <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\">. The <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> bothering you could be <\/span><span style=\"font-weight: 400;\">weight gain<\/span><span style=\"font-weight: 400;\">, diabetes, high <\/span><span style=\"font-weight: 400;\">cholesterol<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">dry mouth<\/span><span style=\"font-weight: 400;\">, <\/span><span style=\"font-weight: 400;\">constipation<\/span><span style=\"font-weight: 400;\">, low blood pressure, or others. If you find yourself in this situation with <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">, a thoughtful, cautious approach is needed to analyze the risks and benefits of the medication. Gather information and see your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> for <\/span><span style=\"font-weight: 400;\">medical advice<\/span><span style=\"font-weight: 400;\"> before making any changes. Information on alternatives to <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> will be covered for you here.<\/span><\/p>\n<h2 id=\"what-can-i-take-in-place-of-olanzapine\"><span style=\"font-weight: 400;\">What can I take in place of <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Olanzapine<\/span><span style=\"font-weight: 400;\"> is better known by its brand name, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa\/what-is\"><span style=\"font-weight: 400;\">Zyprexa<\/span><\/a><span style=\"font-weight: 400;\">. The drug is considered an <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">antipsychotic<\/span><\/a><span style=\"font-weight: 400;\">, more specifically a <\/span><span style=\"font-weight: 400;\">second-generation<\/span><span style=\"font-weight: 400;\"> antipsychotic or <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/atypical-antipsychotics\"><span style=\"font-weight: 400;\">atypical antipsychotic<\/span><\/a><span style=\"font-weight: 400;\">. This class has a number of members, each with its own unique characteristics. Just because <\/span><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> does not work out for you does not mean that another <\/span><span style=\"font-weight: 400;\">second-generation<\/span><span style=\"font-weight: 400;\"> antipsychotic will not.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Differences between them include <\/span><span style=\"font-weight: 400;\">side effect<\/span><span style=\"font-weight: 400;\"> risk and drug interaction rates, so a switch to another member of the class could make sense for mood stabilization in <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><span style=\"font-weight: 400;\"> or for <\/span><span style=\"font-weight: 400;\">psychosis<\/span><span style=\"font-weight: 400;\"> in <\/span><span style=\"font-weight: 400;\">schizophrenia<\/span><span style=\"font-weight: 400;\"> and <\/span><span style=\"font-weight: 400;\">schizoaffective disorders<\/span><span style=\"font-weight: 400;\">. If not, other <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/mood-stabilizers\"><span style=\"font-weight: 400;\">mood stabilizer<\/span><\/a><span style=\"font-weight: 400;\"> options for bipolar are available. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/lithium-carbonate-er\/what-is\"><span style=\"font-weight: 400;\">Lithium<\/span><\/a><span style=\"font-weight: 400;\"> and antiepileptic drugs (seizure controllers) can be effective for bipolar control. While more limited options exist for <\/span><span style=\"font-weight: 400;\">schizophrenia<\/span><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/typical-antipsychotics\"><span style=\"font-weight: 400;\">first-generation <\/span><span style=\"font-weight: 400;\">antipsychotic drugs<\/span><\/a><span style=\"font-weight: 400;\"> are an alternative.&nbsp;<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"compare-olanzapine-alternatives\"><span class=\"title\">Compare olanzapine alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder mania or mixed or acute depressive, acute treatment-resistant major depressive disorder<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5 to 20 mg once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa\"><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> Relprevv (<\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">150 to 300 mg intramuscular (IM) injection every 2 weeks or 150 to 405 mg IM injection every 4 weeks<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa-relprevv\"><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> Relprevv coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> Zydis (<\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder mania or mixed or acute depressive, acute treatment-resistant major depressive disorder<\/span><\/td>\n<td><span style=\"font-weight: 400;\">5 to 20 mg orally disintegrating tablet (ODT) once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/zyprexa-zydis\"><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> Zydis coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Seroquel (<\/span><span style=\"font-weight: 400;\">quetiapine<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder mania or acute depressive<\/span><\/td>\n<td><span style=\"font-weight: 400;\">100 to 400 mg twice daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/seroquel\"><span style=\"font-weight: 400;\">Seroquel coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Seroquel XR (<\/span><span style=\"font-weight: 400;\">quetiapine<\/span><span style=\"font-weight: 400;\"> extended-release)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder mania or mixed or acute depressive<\/span><\/td>\n<td><span style=\"font-weight: 400;\">300 to 800 mg once daily&nbsp;<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/seroquel-xr\"><span style=\"font-weight: 400;\">Seroquel XR coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Abilify<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">aripiprazole<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder mania or mixed, major depressive disorder adjunct to <\/span><span style=\"font-weight: 400;\">antidepressants<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2 to 15 mg once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/abilify\"><span style=\"font-weight: 400;\">Abilify<\/span><span style=\"font-weight: 400;\"> coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Risperdal (<\/span><span style=\"font-weight: 400;\">risperidone<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder acute mania or mixed<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 to 6 mg once daily or divided into two doses<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/risperdal\"><span style=\"font-weight: 400;\">Risperdal coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Latuda (lurasidone)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder acute depressive<\/span><\/td>\n<td><span style=\"font-weight: 400;\">20 to 160 mg once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/latuda\"><span style=\"font-weight: 400;\">Latuda coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Geodon (<\/span><span style=\"font-weight: 400;\">ziprasidone<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><span style=\"font-weight: 400;\">, bipolar 1 disorder mania or mixed<\/span><\/td>\n<td><span style=\"font-weight: 400;\">20 to 80 mg twice daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/geodon\"><span style=\"font-weight: 400;\">Geodon coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Clozaril<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">clozapine<\/span><span style=\"font-weight: 400;\">)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Schizophrenia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">150 to 300 mg twice daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/clozaril\"><span style=\"font-weight: 400;\">Clozaril<\/span><span style=\"font-weight: 400;\"> coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Haloperidol<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Psychosis<\/span><span style=\"font-weight: 400;\">, Tourette syndrome<\/span><\/td>\n<td><span style=\"font-weight: 400;\">0.5 to 5 mg two to three times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/haloperidol\"><span style=\"font-weight: 400;\">Haloperidol<\/span><span style=\"font-weight: 400;\"> coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Lithobid (<\/span><span style=\"font-weight: 400;\">lithium<\/span><span style=\"font-weight: 400;\"> extended-release)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Bipolar 1 disorder maintenance and acute mania<\/span><\/td>\n<td><span style=\"font-weight: 400;\">300 to 600 mg two to three times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lithobid\"><span style=\"font-weight: 400;\">Lithobid coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Depakote (valproic acid)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Bipolar disorder<\/span><span style=\"font-weight: 400;\"> acute mania, complex partial seizures, absence seizures, migraine headache prophylaxis<\/span><\/td>\n<td><span style=\"font-weight: 400;\">250 to 500 mg twice daily for <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/depakote\"><span style=\"font-weight: 400;\">Depakote coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Depakote ER (divalproex extended-release)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Bipolar disorder<\/span><span style=\"font-weight: 400;\"> acute mania, complex partial seizures, absence seizures, migraine headache prophylaxis<\/span><\/td>\n<td><span style=\"font-weight: 400;\">25 to 60 mg per kg of body weight once daily for <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/depakote-er\"><span style=\"font-weight: 400;\">Depakote ER coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Tegretol (carbamazepine)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Bipolar disorder<\/span><span style=\"font-weight: 400;\"> (<\/span><a href=\"https:\/\/www.singlecare.com\/blog\/off-label-prescription-drugs\/\"><span style=\"font-weight: 400;\">off-label<\/span><\/a><span style=\"font-weight: 400;\">), seizure disorder, trigeminal neuralgia<\/span><\/td>\n<td><span style=\"font-weight: 400;\">800 to 1200 mg per day divided into two to four doses for <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/tegretol\"><span style=\"font-weight: 400;\">Tegretol coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Lamictal (lamotrigine)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Bipolar 1 disorder maintenance, seizures<\/span><\/td>\n<td><span style=\"font-weight: 400;\">100 to 200 mg once daily for <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/lamictal\"><span style=\"font-weight: 400;\">Lamictal coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 id=\"other-alternatives-to-olanzapine\"><span style=\"font-weight: 400;\">Other alternatives to <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/abilify-maintena\"><span style=\"font-weight: 400;\">Abilify<\/span><span style=\"font-weight: 400;\"> Maintena<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">aripiprazole<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/abilify-mycite-starter-kit\"><span style=\"font-weight: 400;\">Abilify<\/span><span style=\"font-weight: 400;\"> MyCite<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">aripiprazole<\/span><span style=\"font-weight: 400;\">)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/risperdal-consta\"><span style=\"font-weight: 400;\">Risperdal Consta<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">risperidone<\/span><span style=\"font-weight: 400;\">)&nbsp;<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/saphris\"><span style=\"font-weight: 400;\">Saphris<\/span><\/a><span style=\"font-weight: 400;\"> (asenapine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/rexulti\"><span style=\"font-weight: 400;\">Rexulti<\/span><\/a><span style=\"font-weight: 400;\"> (brexpiprazole)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/vraylar\"><span style=\"font-weight: 400;\">Vraylar<\/span><\/a><span style=\"font-weight: 400;\"> (cariprazine)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/fanapt\"><span style=\"font-weight: 400;\">Fanapt<\/span><\/a><span style=\"font-weight: 400;\"> (iloperidone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/caplyta\"><span style=\"font-weight: 400;\">Caplyta<\/span><\/a><span style=\"font-weight: 400;\"> (lumateperone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/invega\"><span style=\"font-weight: 400;\">Invega<\/span><\/a><span style=\"font-weight: 400;\"> (paliperidone extended release)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/invega-sustenna\"><span style=\"font-weight: 400;\">Invega Sustenna<\/span><\/a><span style=\"font-weight: 400;\"> (paliperidone palmitate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/invega-trinza\"><span style=\"font-weight: 400;\">Invega Trinza<\/span><\/a><span style=\"font-weight: 400;\"> (paliperidone palmitate)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/loxapine-succinate\"><span style=\"font-weight: 400;\">Loxapine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/chlorpromazine-hcl\"><span style=\"font-weight: 400;\">Chlorpromazine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/perphenazine\"><span style=\"font-weight: 400;\">Perphenazine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/fluphenazine-hcl\"><span style=\"font-weight: 400;\">Fluphenazine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/thioridazine-hcl\"><span style=\"font-weight: 400;\">Thioridazine<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/prochlorperazine-maleate\"><span style=\"font-weight: 400;\">Prochlorperazine maleate<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/prescription\/thiothixene\"><span style=\"font-weight: 400;\">Thiothixene<\/span><\/a><\/li>\n<\/ul>\n<h2 id=\"top-5-olanzapine-alternatives\"><span style=\"font-weight: 400;\">Top 5 <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most common alternatives to <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"1-seroquel\"><span style=\"font-weight: 400;\">1. Seroquel<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The compelling advantage of <\/span><span style=\"font-weight: 400;\">second-generation<\/span> <a href=\"https:\/\/www.singlecare.com\/drug-classes\/antipsychotics\"><span style=\"font-weight: 400;\">antipsychotics<\/span><\/a><span style=\"font-weight: 400;\"> compared to their predecessors is the considerably lower risk of tremor, rigidity, <\/span><span style=\"font-weight: 400;\">akathisia<\/span><span style=\"font-weight: 400;\"> (restlessness), and trouble swallowing. This array of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> is termed <\/span><span style=\"font-weight: 400;\">extrapyramidal symptoms<\/span><span style=\"font-weight: 400;\"> (EPS) or <\/span><span style=\"font-weight: 400;\">parkinsonism<\/span><span style=\"font-weight: 400;\"> for its similarity to Parkison&rsquo;s disease. Similarly, <\/span><span style=\"font-weight: 400;\">second-generation<\/span><span style=\"font-weight: 400;\"> antipsychotics have a much lower incidence of the <\/span><span style=\"font-weight: 400;\">adverse effect<\/span><span style=\"font-weight: 400;\"> called <\/span><span style=\"font-weight: 400;\">tardive dyskinesia<\/span><span style=\"font-weight: 400;\"> (TD), typified by abnormal movements like lip smacking, tongue thrusting, extremity writhing, and facial grimacing. Although all members of the class have less EPS and TD than first-generation antipsychotics, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/seroquel\/what-is\"><span style=\"font-weight: 400;\">Seroquel<\/span><\/a><span style=\"font-weight: 400;\"> may be a better option than <\/span><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\"> for those at highest risk of movement-related <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/seroquel-side-effects\/\"><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\">. If you are having <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\"> on your movement, then a change could be sensible.<\/span><\/p>\n<h3 id=\"2-abilify\"><span style=\"font-weight: 400;\">2. <\/span><span style=\"font-weight: 400;\">Abilify<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The most troublesome constellation of <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> of <\/span><span style=\"font-weight: 400;\">second-generation<\/span><span style=\"font-weight: 400;\"> antipsychotics is related to metabolic consequences. <\/span><span style=\"font-weight: 400;\">Weight gain<\/span><span style=\"font-weight: 400;\">, diabetes, and elevated <\/span><span style=\"font-weight: 400;\">cholesterol<\/span><span style=\"font-weight: 400;\"> can all be <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/abilify-side-effects\/\"><span style=\"font-weight: 400;\">experienced<\/span><\/a><span style=\"font-weight: 400;\">. The risk is large enough that <\/span><a href=\"https:\/\/diabetesjournals.org\/care\/article\/27\/2\/596\/28450\/Consensus-Development-Conference-on-Antipsychotic\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">regular monitoring<\/span><\/a><span style=\"font-weight: 400;\"> is recommended during treatment. Warnings about <\/span><span style=\"font-weight: 400;\">sedation<\/span><span style=\"font-weight: 400;\"> or <\/span><span style=\"font-weight: 400;\">sleepiness<\/span><span style=\"font-weight: 400;\"> are also necessary with <\/span><span style=\"font-weight: 400;\">antipsychotic medication<\/span><span style=\"font-weight: 400;\">. If you have problems with adverse metabolic effects or <\/span><span style=\"font-weight: 400;\">sedation<\/span><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/abilify\/what-is\"><span style=\"font-weight: 400;\">Abilify<\/span><\/a><span style=\"font-weight: 400;\"> has been <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19821375\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">found to have a lower incidence of these <\/span><span style=\"font-weight: 400;\">side effects<\/span><\/a><span style=\"font-weight: 400;\"> than <\/span><span style=\"font-weight: 400;\">Zyprexa<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"3-geodon\"><span style=\"font-weight: 400;\">3. Geodon<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Sexual <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> can also plaque users of antipsychotics. The effects can involve loss of libido, less arousal, and difficulty with orgasm. While any of the drug class members can be problematic in this way, about half of <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> users experienced sexual <\/span><span style=\"font-weight: 400;\">side effects<\/span><span style=\"font-weight: 400;\"> compared to only a quarter of <\/span><span style=\"font-weight: 400;\">ziprasidone<\/span><span style=\"font-weight: 400;\"> users in a study. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/geodon\/what-is\"><span style=\"font-weight: 400;\">Geodon<\/span><\/a><span style=\"font-weight: 400;\"> is the brand name of <\/span><span style=\"font-weight: 400;\">ziprasidone<\/span><span style=\"font-weight: 400;\">. It is no guarantee that <\/span><span style=\"font-weight: 400;\">sexual dysfunction<\/span><span style=\"font-weight: 400;\"> symptoms would resolve with a change to Geodon, but it may be worth considering.<\/span><\/p>\n<h3 id=\"4-latuda\"><span style=\"font-weight: 400;\">4. Latuda<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Cardiovascular risks are another concern for those taking antipsychotics. A change to electrical impulse conduction in the heart called QT prolongation can occur, and it is associated with dangerous, even fatal, heart rhythm problems. The likelihood of this <\/span><span style=\"font-weight: 400;\">serious side effect<\/span><span style=\"font-weight: 400;\"> is low overall but is significant for those with heart problems or taking other medications that affect the QT interval of cardiac conduction. A <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> professional can help assess your risk of QT prolongation. Besides this heart rhythm issue, <\/span><span style=\"font-weight: 400;\">second-generation<\/span><span style=\"font-weight: 400;\"> antipsychotics can also provoke drops in blood pressure upon standing up, a condition called <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/low-blood-pressure\/\"><span style=\"font-weight: 400;\">orthostatic hypotension<\/span><\/a><span style=\"font-weight: 400;\">. Conversely, one&rsquo;s heart rate can jump up with position changes during drug therapy. The obvious concern is a risk of syncope (passing out) and falling with these blood pressure or heart rate changes. <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2013\/200603lbls10s11.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Latuda<\/span><\/a><span style=\"font-weight: 400;\"> seems to have less risk of these different cardiovascular effects than <\/span><a href=\"https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2009\/020592s051,021086s030,021253s036lbl.pdf\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Zyprexa<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<h3 id=\"5-depakote\"><span style=\"font-weight: 400;\">5. Depakote<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">To this point, the discussion has focused on <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\"> as a reason to potentially seek an alternative to <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">. Efficacy could be the problem instead. If you are taking <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> for maintenance of <\/span><span style=\"font-weight: 400;\">bipolar disorder<\/span><span style=\"font-weight: 400;\">, you are probably doing so because it helped to get you controlled initially. Typically, whichever mood stabilizer drug helped to achieve control is the one to be continued. In the situation in which it stops working, finding another option may be necessary. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/depakote\/what-is\"><span style=\"font-weight: 400;\">Depakote<\/span><\/a><span style=\"font-weight: 400;\"> is a common choice in this situation, although it should not be used if there is a chance of pregnancy, due to its <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\"> on the fetus.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In <\/span><span style=\"font-weight: 400;\">treatment of schizophrenia<\/span><span style=\"font-weight: 400;\">, the second-generative antipsychotics all have similar effectiveness, but <\/span><span style=\"font-weight: 400;\">clozaril<\/span><span style=\"font-weight: 400;\"> has been found in <\/span><span style=\"font-weight: 400;\">clinical trials<\/span><span style=\"font-weight: 400;\"> to be <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27388573\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">effective when other options have failed<\/span><\/a><span style=\"font-weight: 400;\">. <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/clozaril\/what-is\"><span style=\"font-weight: 400;\">Clozaril<\/span><span style=\"font-weight: 400;\">&rsquo;s<\/span><\/a><span style=\"font-weight: 400;\"> association with heart problems, blood cell disorders, and seizures has led to warnings about its use and keeps it from being a popular choice.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Finding an alternative when <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> is letting you down in terms of effectiveness will likely involve an in depth discussion with the prescribing provider. Each medication has its own unique advantages, pitfalls, and potential effects on <\/span><span style=\"font-weight: 400;\">quality of life<\/span><span style=\"font-weight: 400;\">.&nbsp;<\/span><\/p>\n<h2 id=\"natural-alternatives-to-olanzapine\"><span style=\"font-weight: 400;\">Natural alternatives to <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Even natural options can have <\/span><span style=\"font-weight: 400;\">adverse effects<\/span><span style=\"font-weight: 400;\">, but regardless, there are many who gravitate toward these types of alternatives. Evidence to support <\/span><span style=\"font-weight: 400;\">dietary<\/span> <span style=\"font-weight: 400;\">supplement<\/span><span style=\"font-weight: 400;\"> use for <\/span><span style=\"font-weight: 400;\">psychosis<\/span><span style=\"font-weight: 400;\"> is not robust, but as an add-on to <\/span><span style=\"font-weight: 400;\">antipsychotic medication<\/span><span style=\"font-weight: 400;\">, there are options that may be helpful. There is some supportive data for <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5794244\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">adjunctive use of glycine, sarcosine, <\/span><i><span style=\"font-weight: 400;\">N<\/span><\/i><span style=\"font-weight: 400;\">-acetylcysteine, ginkgo biloba, estradiol, and vitamin B6 for <\/span><span style=\"font-weight: 400;\">psychosis<\/span><\/a><span style=\"font-weight: 400;\">. Adjunctive use means they are used in addition to prescription antipsychotics. In addition, a healthy <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/the-best-diet-for-mental-health\/\"><span style=\"font-weight: 400;\">diet <\/span><\/a><span style=\"font-weight: 400;\">may help. For example, a <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2248201\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">reduction in refined sugars and an increase in omega-3 fatty acids<\/span><\/a><span style=\"font-weight: 400;\"> are measures that seem beneficial.<\/span><\/p>\n<h2 id=\"how-to-switch-to-an-olanzapine-alternative\"><span style=\"font-weight: 400;\">How to switch to an <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Taking a new <\/span><span style=\"font-weight: 400;\">dietary<\/span> <span style=\"font-weight: 400;\">supplement<\/span><span style=\"font-weight: 400;\"> or over-the-counter medication, changing one of your prescription drugs, and contemplating a new prescription alternative are all actions with substantial risk potential. Accordingly, they should only be done with the guidance of a <\/span><span style=\"font-weight: 400;\">healthcare<\/span><span style=\"font-weight: 400;\"> professional. If cost is a main concern in seeking an alternative treatment, <\/span><a href=\"https:\/\/www.singlecare.com\/prescription-discount-card\"><span style=\"font-weight: 400;\">SingleCare<\/span><\/a><span style=\"font-weight: 400;\"> can help. The information that you now have about alternatives to <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\"> can be brought up when you have your appointment. Collectively, you and your <\/span><span style=\"font-weight: 400;\">healthcare provider<\/span><span style=\"font-weight: 400;\"> can decide on how to move forward with or without <\/span><span style=\"font-weight: 400;\">olanzapine<\/span><span style=\"font-weight: 400;\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Olanzapine may serve as a pivotal piece of your mental health maintenance. By influencing the action of brain neurotransmitters, namely dopamine and serotonin, it can halt schizophrenia&rsquo;s psychotic symptoms, like hallucinations, paranoia, and delusions, and bipolar disorder&rsquo;s manic and depressive symptoms. Thereafter, olanzapine is often continued long-term for prevention of these problems. Your enthusiasm for [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":54942,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[450],"coauthors":[20732],"class_list":["post-54920","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-mental-health","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top olanzapine alternatives and how to switch your Rx | SingleCare<\/title>\n<meta name=\"description\" content=\"Seroquel, Abilify, Geodon, Latuda, and Depakote are some olanzapine alternatives. Get the full list here, including natural remedies to manage psychosis.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.singlecare.com\/blog\/olanzapine-alternatives\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Olanzapine alternatives: What can I take instead of olanzapine?\" \/>\n<meta property=\"og:description\" content=\"Seroquel, Abilify, Geodon, Latuda, and Depakote are some olanzapine alternatives. 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During her time in college, she developed a passion for helping children and volunteers as a Court Appointed Special Advocate on behalf of foster youth.\",\"url\":\"https:\\\/\\\/www.singlecare.com\\\/blog\\\/author\\\/cfalzone\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Top olanzapine alternatives and how to switch your Rx | SingleCare","description":"Seroquel, Abilify, Geodon, Latuda, and Depakote are some olanzapine alternatives. 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