{"id":55032,"date":"2022-11-11T13:23:27","date_gmt":"2022-11-11T18:23:27","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=55032"},"modified":"2025-10-17T16:58:00","modified_gmt":"2025-10-17T20:58:00","slug":"desvenlafaxine-side-effects","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/desvenlafaxine-side-effects\/","title":{"rendered":"Desvenlafaxine side effects and how to avoid them"},"content":{"rendered":"

Desvenlafaxine<\/span><\/a> is a generic prescription <\/span>antidepressant<\/span><\/a> used to treat <\/span>major depressive disorder<\/span><\/a> (<\/span>MDD<\/span>) in adults. It has some off-label uses, as well: relieving nerve pain and, in menopausal women who cannot take estrogen, reducing hot flashes. <\/span>Desvenlafaxine<\/span> is closely related to another <\/span>antidepressant<\/span>, <\/span>Effexor<\/span><\/a> (<\/span>venlafaxine<\/span><\/a>). Like <\/span>venlafaxine<\/span>, <\/span>desvenlafaxine<\/span> is a <\/span>serotonin-norepinephrine reuptake inhibitor<\/span> (<\/span>SNRI<\/span><\/a>). By prolonging the duration of these two chemicals in the brain, <\/span>desvenlafaxine<\/span> helps increase activity in the part of the brain responsible for mood control.\u00a0<\/span><\/p>\n

Desvenlafaxine<\/span><\/a> and its <\/span>brand-name<\/span> versions <\/span>Pristiq<\/span><\/a> and <\/span>Khedezla<\/span> are all taken as <\/span>extended-release tablets<\/span>. They have many of the same <\/span>side effects<\/span> as other <\/span>antidepressants<\/span>, with one major difference: there are <\/span>fewer <\/span>drug interactions<\/span><\/a> to worry about when taking <\/span>desvenlafaxine<\/span>.<\/span><\/p>\n

Common side effects of desvenlafaxine<\/span><\/h2>\n

Nausea is the most <\/span>common side effect of <\/span>desvenlafaxine<\/span><\/a>. <\/span>In order of prevalence<\/span><\/a>, the most <\/span>common side effects of desvenlafaxine<\/span> are:<\/span><\/p>\n