{"id":55053,"date":"2022-11-09T09:30:27","date_gmt":"2022-11-09T14:30:27","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=55053"},"modified":"2025-09-30T17:40:28","modified_gmt":"2025-09-30T21:40:28","slug":"hydroxyzine-and-caffeine","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/hydroxyzine-and-caffeine\/","title":{"rendered":"Is it safe to mix hydroxyzine and caffeine?"},"content":{"rendered":"

You might have been prescribed <\/span>hydroxyzine<\/span><\/a> because you had an allergic reaction\u2014or even to <\/span>manage anxiety symptoms<\/span><\/a>. One of its side effects is drowsiness. Naturally, you are wondering, \u201cCan I drink coffee while taking hydroxyzine?\u201d It\u2019s a common question, especially if you need to take this medication during daytime hours.<\/span><\/p>\n

\u201cHydroxyzine is an interesting drug because it can be prescribed for a variety of different uses,\u201d says Frank J. Contacessa, MD, an internist at <\/span>MDVIP<\/span> in Palm Beach Gardens, Florida. \u201cIt can be used to treat nausea and vomiting, anxiety, and insomnia, as well as allergic conditions like chronic itching and rashes.\u201d<\/span><\/p>\n\t\t

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Do hydroxyzine and caffeine interact?<\/span><\/h2>\n

According to the experts, there are no harmful hydroxyzine interactions with caffeine. \u201cThere is no significant interaction between hydroxyzine and caffeine,\u201d says <\/span>Brandon Cometti<\/span>, MD, a dermatologist at Roswell Skin Center in New Mexico. \u201cHydroxyzine is a sedating antihistamine, so it can make you drowsy, while caffeine is a stimulant, so it can make you more alert. The effects may cancel each other out a bit, but there are no harmful interactions.\u201d<\/span><\/p>\n

How much caffeine can you have with hydroxyzine?<\/span><\/h3>\n

Even though there isn\u2019t a limit to the amount of caffeine you can have with hydroxyzine, taking too much caffeine can be harmful. \u201cThere is no specific limit,\u201d Dr. Cometti says. \u201cYou can drink your normal amount of caffeine. In general, it is best to limit caffeine to less than about 400 mg a day\u2014that’s equal to about four 8 oz cups of brewed coffee [or five shots of espresso].\u201d<\/span><\/p>\n

Can I drink coffee while taking hydroxyzine?<\/span><\/h2>\n

\u201cIt is not harmful for people to drink coffee while taking antihistamines for allergies,\u201d Dr. Cometti says. In fact, caffeine could help counteract the sedating effects of antihistamines, according to Dr. Cometti.<\/span><\/p>\n

Some people even choose to drink caffeine to help them feel less drowsy. \u201cIt\u2019s safe to take hydroxyzine and drink coffee or take meds that contain caffeine. In fact, some people prefer drinking coffee after taking hydroxyzine because the former is a stimulant that can alleviate drowsiness caused by hydroxyzine,\u201d says <\/span>Po-Chang Hsu<\/span><\/a>, MD, a medical content expert for Sleeping Ocean.<\/span><\/p>\n

Because there is no harmful interaction between hydroxyzine and caffeine, it\u2019s okay to mix hydroxyzine and coffee in many cases. \u201cIt is perfectly fine to drink coffee while taking hydroxyzine,\u201d Dr. Cometti says. \u201cIf you are taking hydroxyzine for allergies and need to stay more awake and alert, coffee or caffeine may help a bit.\u201d<\/span><\/p>\n

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