{"id":55536,"date":"2022-12-02T09:30:06","date_gmt":"2022-12-02T14:30:06","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=55536"},"modified":"2026-03-10T14:50:53","modified_gmt":"2026-03-10T18:50:53","slug":"amoxicillin-and-alcohol","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/amoxicillin-and-alcohol\/","title":{"rendered":"Do amoxicillin and alcohol mix?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">If you come down with a bacterial infection, like strep throat, you may be prescribed an antibiotic such as amoxicillin. Treatment with amoxicillin typically lasts for several days, so you might be wondering whether combining amoxicillin and alcohol is safe, especially if the treatment course falls on a weekend or special occasion when you might be offered a cocktail or a glass of wine.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But can you drink on amoxicillin? Fortunately, it\u2019s less likely than other medications to have a severe interaction with alcohol. For the most part, combining alcohol and amoxicillin should not cause any problems as long as you drink in moderation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, the low risk of problems while combining alcohol and amoxicillin is not absolute. The side effects of amoxicillin and alcohol can overlap, which could lead to nausea or an upset stomach. In addition, heavy alcohol use can weaken the immune system and delay healing, the opposite of what your body needs to fight off an infection. Continue reading to learn more about what happens when you mix amoxicillin and alcohol.\u00a0<\/span><\/p>\n\t\t<div id=\"coupon-cta\" class=\"coupon-cta master-template\">\n\t\t\t<p id=\"headline\">Save up to 80% on Amoxicillin with SingleCare<\/p>\n\t\t\t<p id=\"subheadline\">Different pharmacies offer different prices for the same medication. SingleCare helps find the best price for you.<\/p>\n\t\t\t<div class=\"details-wrap\">\n\t\t\t\t<div class=\"details\">\n\t\t\t\t\tAmoxicillin 500 mg (21 Capsules)\t\t\t\t<\/div>\n\t\t\t\t<div class=\"address\">\n\t\t\t\t\t23666 - Hampton, VA\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"api-response\">\n\t\t\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart-nbh-market.svg\" alt=\"Walmart Neighborhood Market\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.22<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/amoxicillin#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/amoxicillin#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"coupon\">\n\t\t\t<div class=\"logo\">\n\t\t\t<img decoding=\"async\" src=\"https:\/\/images.singlecare.com\/content\/images\/pharmacy\/logo-color-walmart.svg\" alt=\"Walmart Pharmacy\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"price\">\n\t\t\t\t<div class=\"price-number\">\n\t\t\t\t\t$3.22<br\/>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"price-signup\">\n\t\t\t\t\t<span class=\"info-icon\">i<\/span>\n\t\t\t\t\tPrice with <a href=\"https:\/\/www.singlecare.com\/prescription\/amoxicillin#blog-cta\">signup<\/a>\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t\t<div class=\"couponbtn\">\n\t\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/amoxicillin#blog-cta\">Get free coupon<\/a>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t<a target=\"_blank\" href=\"https:\/\/www.singlecare.com\/prescription\/amoxicillin#blog-cta\" class=\"coupon-see-all-btn\">See Amoxicillin prices at all pharmacies<\/a>\n\t\t<\/div>\n\n\t\t\n<h2 id=\"what-is-amoxicillin\"><span style=\"font-weight: 400;\">What is amoxicillin?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Amoxicillin, known by different brand names like Amoxil, Moxatag, and Trimax, belongs to the<\/span> <a href=\"https:\/\/www.singlecare.com\/drug-classes\/penicillins\"><span style=\"font-weight: 400;\">penicillin<\/span><\/a><span style=\"font-weight: 400;\"> family of antibiotics. Introduced in 1974, it is FDA approved for treating bacterial infections of the ear, nose, throat, lower respiratory tract, urinary tract, and skin. Available in various forms, including regular tablets, chewable tablets, and oral suspensions, it is usually taken every 8 to 12 hours for up to 10 days or longer. The dosage and duration of treatment depend on the infection being treated. Amoxicillin is not effective against viral or fungal infections.\u00a0<\/span><\/p>\n<h3 id=\"amoxicillin-side-effects\"><span style=\"font-weight: 400;\">Amoxicillin side effects<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Amoxicillin may cause <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/amoxicillin-side-effects\/\"><span style=\"font-weight: 400;\">mild to severe side effects<\/span><\/a><span style=\"font-weight: 400;\">. In most cases, the side effects of amoxicillin are mild and temporary.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Common side effects of amoxicillin include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rash<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Headache<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stomach pain<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diarrhea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nausea<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vomiting<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Serious side effects of amoxicillin include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.singlecare.com\/conditions\/clostridium-difficile-treatment-and-medications\"><span style=\"font-weight: 400;\">Clostridioides difficile-associated diarrhea<\/span><\/a><span style=\"font-weight: 400;\">, which can cause severe abdominal pain or cramping.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Severe allergic reactions (hives, swelling of the face, and trouble breathing)\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kidney inflammation or liver injury<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blood disorders, such as anemia or low platelet counts<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Seizures<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Not everyone experiences side effects while taking amoxicillin. However, it\u2019s important to seek medical help if serious side effects develop or worsen.<\/span><\/p>\n<h2 id=\"can-you-mix-amoxicillin-and-alcohol\"><span style=\"font-weight: 400;\">Can you mix amoxicillin and alcohol?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">When considering whether you can drink alcohol while taking amoxicillin, the answer is nuanced. You likely won\u2019t have to avoid drinking alcohol completely while taking amoxicillin. As long as you stick to low to moderate alcohol consumption (two drinks or fewer per day for men and one drink or fewer per day for women), the risk of serious side effects is low.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In general, drinking a glass of red wine with dinner shouldn\u2019t be a problem. However, if you\u2019re planning on drinking several glasses, you might be in trouble.\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-635566\" src=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/12\/Embed_030626_amoxicillin.png\" alt=\"A chart showing the safety of combining amoxicillin and alcohol\" width=\"1920\" height=\"900\" srcset=\"https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/12\/Embed_030626_amoxicillin.png 1920w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/12\/Embed_030626_amoxicillin-300x141.png 300w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/12\/Embed_030626_amoxicillin-1024x480.png 1024w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/12\/Embed_030626_amoxicillin-768x360.png 768w, https:\/\/www.singlecare.com\/blog\/wp-content\/uploads\/2022\/12\/Embed_030626_amoxicillin-1536x720.png 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \/><\/p>\n<h3 id=\"problems-with-drinking-alcohol-with-an-infection\"><span style=\"font-weight: 400;\">Problems with drinking alcohol with an infection<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Although alcohol does not directly interact with amoxicillin, alcohol can have other effects on the body that can be detrimental during an infection. Here are the main drawbacks of mixing amoxicillin and alcohol:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Increased side effects:<\/b><span style=\"font-weight: 400;\"> Binge drinking can worsen nausea, headache, and an upset stomach, common side effects of mixing the amoxicillin antibiotic with alcohol. Additionally, if you have a fever or dehydration, alcohol can worsen these symptoms.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Increased liver or kidney stress: <\/b><span style=\"font-weight: 400;\">Both alcohol and amoxicillin are processed by the liver and kidneys, leading to potential stress on these organs.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Risk of missed doses:<\/b><span style=\"font-weight: 400;\"> Alcohol may impair your ability to stick to your prescribed schedule.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Immune system effects:<\/b><span style=\"font-weight: 400;\"> Alcohol can weaken the immune response, making recovery more challenging<\/span><span style=\"font-weight: 400;\">. <\/span><span style=\"font-weight: 400;\">People who have been diagnosed with alcohol use disorder or alcohol addiction may have a harder time fighting infections<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Dehydration:<\/b><span style=\"font-weight: 400;\"> Alcohol can act as <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6761819\/\"><span style=\"font-weight: 400;\">a diuretic<\/span><\/a><span style=\"font-weight: 400;\">, which can cause the body to get rid of fluids quickly, potentially causing dehydration. Drinking lots of fluids and staying hydrated are essential parts of self-care when dealing with an illness or infection.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Healthcare professionals will generally recommend you avoid alcohol while you\u2019re sick to avoid these effects and help your body get much-needed rest to fight an infection.\u00a0<\/span><\/p>\n<h2 id=\"amoxicillin-and-alcohol-interaction\"><span style=\"font-weight: 400;\">Amoxicillin and alcohol interaction<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There is no mention of an amoxicillin and alcohol interaction in the FDA drug label for amoxicillin. Mixing amoxicillin and alcohol is not known to cause a severe reaction. In addition, alcohol will not directly affect how well amoxicillin works.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In some cases, you may be prescribed <\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/augmentin\"><span style=\"font-weight: 400;\">Augmentin<\/span><\/a><span style=\"font-weight: 400;\">, which is a combination of amoxicillin and another drug called clavulanate. The risks of drinking alcohol with amoxicillin are similar to Augmentin<\/span><a href=\"https:\/\/www.singlecare.com\/prescription\/augmentin\"><span style=\"font-weight: 400;\">, which <\/span><\/a><span style=\"font-weight: 400;\">is not known to interact with alcohol.<\/span><\/p>\n<h3 id=\"antibiotics-interactions-with-alcohol\"><span style=\"font-weight: 400;\">Antibiotics interactions with alcohol<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Other antibiotics are more likely than amoxicillin to interact with alcohol. For example, <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/metronidazole-and-alcohol\/\"><span style=\"font-weight: 400;\">mixing Flagyl (metronidazole) with alcohol<\/span><\/a><span style=\"font-weight: 400;\"> can lead to a disulfiram-like reaction that can cause flushing, nausea, headache, rapid heart rate, and increased blood pressure. Tindamax (tinidazole) and Bactrim (sulfamethoxazole\/trimethoprim) are other antibiotics that can lead to a disulfiram-like reaction when mixed with alcohol.\u00a0<\/span><\/p>\n<p><a href=\"https:\/\/www.singlecare.com\/blog\/alcohol-with-antibiotics\/\"><span style=\"font-weight: 400;\">Some antibiotics<\/span><\/a><span style=\"font-weight: 400;\"> can cause other problems when mixed with alcohol. For example, mixing an antibiotic called Nydrazid (isoniazid) with alcohol may increase the risk of liver damage. Chronic, heavy alcohol use can <\/span><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7038249\/\"><span style=\"font-weight: 400;\">reduce the effectiveness<\/span><\/a><span style=\"font-weight: 400;\"> of some antibiotics, such as Vibramycin (doxycycline).\u00a0<\/span><\/p>\n<h2 id=\"how-to-take-amoxicillin-safely\"><span style=\"font-weight: 400;\">How to take amoxicillin safely<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Amoxicillin, like <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/how-do-antibiotics-work\/\"><span style=\"font-weight: 400;\">other antibiotics<\/span><\/a><span style=\"font-weight: 400;\">, can only do its job if it\u2019s being taken correctly and safely. There are some ways to ensure you\u2019re getting the most out of your treatment and avoiding potential side effects.\u00a0<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Take amoxicillin as prescribed. <\/b><span style=\"font-weight: 400;\">Taking a higher dose than normal may increase the risk of side effects. If you need help remembering to take scheduled doses, set an alarm or reminder. While amoxicillin can be taken with or without food, some people experience fewer gastrointestinal side effects when taking it with a meal.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tell your healthcare provider about any medical conditions you have or medications you\u2019re taking.<\/b><span style=\"font-weight: 400;\"> Make sure to tell your provider about any health conditions, such as kidney or liver problems. You should also tell them about other medications you\u2019re taking, including prescription drugs, over-the-counter medicine, and herbal supplements, as possible drug interactions may occur.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Don\u2019t stop taking amoxicillin without talking to a healthcare provider.<\/b><span style=\"font-weight: 400;\"> Abruptly stopping amoxicillin may cause the infection to come back and also lead to <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/finish-antibiotics\/\"><span style=\"font-weight: 400;\">antibiotic resistance<\/span><\/a><span style=\"font-weight: 400;\">, which may require a different antibiotic and a longer treatment duration.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tell your healthcare provider about any side effects that concern you.<\/b><span style=\"font-weight: 400;\"> If you experience unusual stomach pain or other side effects after taking amoxicillin, especially after drinking alcohol, talk to your healthcare provider.\u00a0<\/span><\/li>\n<\/ul>\n<h3 id=\"when-to-consult-a-healthcare-provider\"><span style=\"font-weight: 400;\">When to consult a healthcare provider<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Seek medical advice from a healthcare provider before starting treatment with amoxicillin. A healthcare provider can help guide you on the best way to take your medication to avoid potential side effects and drug interactions.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Seek immediate medical attention if you experience signs or symptoms of an allergic reaction while taking amoxicillin. You should consult a healthcare provider if you experience severe diarrhea that is painful, bloody, or does not seem to go away or get better. You should also consult a healthcare provider if you experience severe nausea and vomiting, particularly if they occur after drinking alcohol with amoxicillin. You may be recommended other treatment options if amoxicillin isn\u2019t right for you.\u00a0<\/span><\/p>\n<h2 id=\"bottom-line\"><span style=\"font-weight: 400;\">Bottom line<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you\u2019re asking yourself if you can take amoxicillin while drinking alcohol, the safest approach is to abstain or limit your alcohol intake significantly. Alcohol shouldn\u2019t affect how amoxicillin works to fight a bacterial infection.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Still, drinking any amount of alcohol may increase certain side effects of amoxicillin, such as nausea and vomiting. Increased alcohol use can also affect the body\u2019s ability to fight an infection and recover.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you come down with a bacterial infection, like strep throat, you may be prescribed an antibiotic such as amoxicillin. Treatment with amoxicillin typically lasts for several days, so you might be wondering whether combining amoxicillin and alcohol is safe, especially if the treatment course falls on a weekend or special occasion when you might [&hellip;]<\/p>\n","protected":false},"author":135,"featured_media":55373,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[8742,715,788],"coauthors":[8669],"class_list":["post-55536","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-alcohol-interactions","tag-antibiotics","tag-drug-safety","franchise-the-mix-up","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Can you take amoxicillin and drink alcohol?<\/title>\n<meta name=\"description\" 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