{"id":55656,"date":"2022-12-14T08:42:13","date_gmt":"2022-12-14T13:42:13","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=55656"},"modified":"2024-10-25T11:00:56","modified_gmt":"2024-10-25T15:00:56","slug":"bevespi-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/bevespi-alternatives\/","title":{"rendered":"Bevespi alternatives: What can I take instead of Bevespi?"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Bevespi Aerosphere is an inhaled brand-name prescription drug product used in the maintenance treatment of <\/span><a href=\"https:\/\/www.singlecare.com\/conditions\/copd-treatment-and-medications\"><span style=\"font-weight: 400;\">chronic obstructive pulmonary disease (COPD)<\/span><\/a><span style=\"font-weight: 400;\">. It is the combination of two drugs, glycopyrrolate, a long-acting muscarinic antagonist (LAMA), and formoterol fumarate, a long-acting beta-agonist (LABA). Although they work via their own distinct mechanisms, LAMAs and LABAs ultimately lead to bronchodilation, or an opening and broadening of the airways. Bevespi is not approved by the Food and Drug Administration (FDA) for the treatment of asthma.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Effective treatment of COPD is an important factor to many. In the United States alone, COPD is estimated to affect <\/span><span style=\"font-weight: 400;\">. It is the fourth leading cause of disability in the United States according to the Centers for Disease Control and Prevention (CDC), and this has effects on society as a whole including the workforce and healthcare system.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">So what is COPD? COPD is comprised of two conditions, and most people who have COPD display symptoms of both to some varying extent. The first condition is emphysema. Your lungs have many air sacs, and the functionality of them is to contract and expand to move air. The walls of the sacs need to be &ldquo;stretchy&rdquo; and healthy in order for this to occur. In emphysema, these sac walls become damaged, and they can no longer contract and expand effectively to move air efficiently. The second condition of COPD is chronic bronchitis. This is characterized by constant irritation and inflammation of the lining of the airways. The presence of thick mucus makes it hard to move air in and through the airways.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There is no cure for COPD. It can prevent even the most basic of life functions like walking, cooking, or bathing. Fortunately, the <\/span><a href=\"https:\/\/www.singlecare.com\/blog\/emphysema-vs-copd\/\"><span style=\"font-weight: 400;\">symptoms of COPD<\/span><\/a><span style=\"font-weight: 400;\"> can often be managed with medications like Bevespi and allow people to live relatively normal lives with COPD along with other healthy lifestyle changes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The manufacturer of <\/span><a href=\"https:\/\/dailymed.nlm.nih.gov\/dailymed\/drugInfo.cfm?setid=ae02436e-9528-490e-a844-0c0f6f2843f9\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Bevespi<\/span><\/a><span style=\"font-weight: 400;\">, AstraZeneca, trialed the combination of glycopyrrolate and formoterol after evaluating the results of each drug on COPD symptoms alone. Bevespi consistently provided better results measured by forced expiratory volume (FEV) as compared to each drug component used alone or as compared to a placebo. Patients on Bevespi also had to use short-acting rescue bronchodilator inhalers like albuterol less frequently.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are some patients for whom Bevespi may not be the ideal choice. Though COPD doesn&rsquo;t typically affect children, Bevespi is not indicated for children or women who are pregnant or breastfeeding. Bevespi should be used cautiously in those with impaired kidney or liver function. Glycopyrrolate is an anticholinergic drug, and this means that there are patients with some conditions where glycopyrrolate should be avoided or used cautiously. These include those with narrow-angle glaucoma, hyperthyroidism, seizure disorder, urinary retention, or chronic urinary tract infections. Formoterol and glycopyrrolate can have negative effects on pre-existing cardiovascular conditions as well, and those should be monitored closely if your doctor chooses to try Bevespi.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Price is always a consideration as well. The manufacturer of Bevespi does offer a savings card, however, the price of Bevespi before insurance approaches $500 per month, and this may make Bevespi unattainable for many. If you are concerned that Bevespi isn&rsquo;t the best choice for you, keep reading. There are other treatment options to discuss with your doctor.<\/span><\/p>\n<h2 id=\"what-can-i-take-in-place-of-bevespi\"><span style=\"font-weight: 400;\">What can I take in place of Bevespi?<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There are other treatment options if Bevespi isn&rsquo;t the right one for you. These include other single drug and combination drug inhalers as well as oral medications. Generally speaking, drugs used in COPD are aimed to either open the airways, decrease mucus production, decrease airway inflammation, or decrease systemic inflammation. This isn&rsquo;t intended to be medical advice. Your doctor or healthcare provider can evaluate your specific symptoms to determine which treatment options are most appropriate for you.<\/span><\/p>\n<table class=\" singlecare-table\">\n<thead>\n<tr>\n<th>\n<h2 id=\"compare-bevespi-alternatives\"><span class=\"title\">Compare Bevespi alternatives<\/span><\/h2>\n<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr class=\"header-row\">\n<td><b>Drug name<\/b><\/td>\n<td><b>Uses<\/b><\/td>\n<td><b>Dosage<\/b><\/td>\n<td><b>Savings options<\/b><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Bevespi (glycopyrrolate\/ formoterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">COPD maintenance treatment<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2 puffs (9\/ 4.8 mcg each) twice daily in the morning and evening<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/bevespi-aerosphere\"><span style=\"font-weight: 400;\">Bevespi coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Symbicort (budesonide\/ formoterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Asthma maintenance treatment, Chronic obstructive pulmonary disease (COPD)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2 puffs (80\/4.5 or 160\/4.5 mcg) inhaled by mouth twice daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/symbicort\"><span style=\"font-weight: 400;\">Symbicort coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Breo Ellipta (fluticasone\/ vilanterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Asthma maintenance treatment, Chronic obstructive pulmonary disease (COPD)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 inhalation (100\/25 mcg) by mouth once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/breo-ellipta\"><span style=\"font-weight: 400;\">Breo Ellipta coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Anoro Ellipta (umeclidinium\/ vilanterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">COPD maintenance treatment<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 actuation (62.5\/25 mcg) by mouth once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/anoro-ellipta\"><span style=\"font-weight: 400;\">Anoro coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Spiriva Handihaler (tiotropium)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">COPD maintenance treatment<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2 inhalations (18 mcg) once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/spiriva-handihaler\"><span style=\"font-weight: 400;\">Spiriva coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Advair Diskus (fluticasone\/ salmeterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Asthma maintenance treatment, Chronic obstructive pulmonary disease (COPD)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 inhalation (250\/50 mcg) twice daily in the morning and evening<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/advair-diskus\"><span style=\"font-weight: 400;\">Advair Diskus coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Incruse Ellipta (umeclidinium)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">COPD maintenance treatment<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 actuation (62.5 mcg) by mouth once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/incruse-ellipta\"><span style=\"font-weight: 400;\">Incruse Ellipta coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Trelegy Ellipta (fluticasone\/ umeclidinium\/ vilanterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Asthma maintenance treatment, Chronic obstructive pulmonary disease (COPD)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">1 inhalation (100\/62.5\/25 mcg) by mouth once daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/trelegy-ellipta\"><span style=\"font-weight: 400;\">Trelegy Ellipta coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Mucomyst (acetylcysteine)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">COPD adjunct treatment, mucus thinning<\/span><\/td>\n<td><span style=\"font-weight: 400;\">3 to 5 ml of the 20% solution nebulized 3-4 times daily<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/acetylcysteine\"><span style=\"font-weight: 400;\">Mucomyst coupons<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td><span style=\"font-weight: 400;\">Ventolin\/ Proventil (albuterol)<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Asthma exacerbation, bronchospasm<\/span><\/td>\n<td><span style=\"font-weight: 400;\">2 puffs (90 mcg each) every 4-6 hours<\/span><\/td>\n<td><a class=\"cta-button\" href=\"https:\/\/www.singlecare.com\/prescription\/ventolin-hfa\"><span style=\"font-weight: 400;\">Ventolin coupons<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 id=\"other-alternatives-to-bevespi\"><span style=\"font-weight: 400;\">Other alternatives to Bevespi<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Advair HFA (fluticasone\/ salmeterol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dulera (mometasone\/ formoterol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Breztri (budesonide\/ glycopyrrolate\/ formoterol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Spiriva Respimat (tiotropium)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Striverdi Respimat (olodaterol)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decadron (dexamethasone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Atrovent (ipratropium)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Medrol (methylprednisolone)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Combivent (albuterol\/ ipratropium)<\/span><\/li>\n<\/ul>\n<h2 id=\"top-5-bevespi-alternatives\"><span style=\"font-weight: 400;\">Top 5 Bevespi alternatives<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">The following are some of the most common alternatives to Bevespi.<\/span><\/p>\n<h3 id=\"1-inhaled-long-acting-beta-2-adrenergic-agonists-laba-and-inhaled-corticosteroid-ics-combinations\"><span style=\"font-weight: 400;\">1. Inhaled long-acting beta 2 adrenergic agonists (LABA) and inhaled corticosteroid (ICS) combinations<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The combination of a LABA drug and a corticosteroid provides bronchodilation effects of the LABA with the anti-inflammatory effects of the corticosteroid. <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/corticosteroids\"><span style=\"font-weight: 400;\">Corticosteroids<\/span><\/a><span style=\"font-weight: 400;\"> can raise blood sugar, and therefore this type of drug combination should be used cautiously in diabetic patients. This drug combination should not be initiated if the patient&#8217;s status is rapidly declining. This is not considered to be life-saving treatment or a rescue inhaler, however, it can be helpful in more minor exacerbations of COPD symptoms and is best utilized as maintenance therapy. This combination is a good option if a LAMA anticholinergic is not a good choice for you.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples: Advair Diskus, Dulera, Symbicort, Breo Ellipta<\/span><\/p>\n<h3 id=\"2-inhaled-long-acting-beta-2-adrenergic-agonists-laba-long-acting-muscarinic-antagonist-lama-and-inhaled-corticosteroid-ics-combinations\"><span style=\"font-weight: 400;\">2. Inhaled long-acting beta 2 adrenergic agonists (LABA), long-acting muscarinic antagonist (LAMA), and inhaled corticosteroid (ICS) combinations<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">This combination of all three categories is often referred to as &ldquo;triple therapy&rdquo; combining two types of bronchodilators and the anti-inflammatory effects of the ICS. This is an appropriate choice when the response to one or two of the drugs is not adequate. Using a combination inhaler improves compliance for patients and makes dosing less cumbersome for them. It may potentially save the patient some out-of-pocket expenses depending on their insurance coverage by reducing to one copay.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples: Trelegy Ellipta, Breztri<\/span><\/p>\n<h3 id=\"3-inhaled-long-acting-muscarinic-antagonist-lama\"><span style=\"font-weight: 400;\">3. Inhaled long-acting muscarinic antagonist (LAMA)<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Daily administration of an inhaled <\/span><a href=\"https:\/\/www.singlecare.com\/drug-classes\/muscarinic-antagonists\"><span style=\"font-weight: 400;\">LAMA<\/span><\/a><span style=\"font-weight: 400;\"> provides bronchodilatory effects which for many are adequate to control COPD symptoms and improve breathing. Spiriva Handihaler (tiotropium) is an inhaler device that utilizes capsules that contain a powder that is aerosolized by the inhaler device. It is important not to swallow the capsule whole. The capsules for the handihaler contain lactose and therefore those with a lactose allergy or hypersensitivity shouldn&rsquo;t use the handihaler. The Spiriva Respimat does not use lactose-containing capsules, and those are safe.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples: Spiriva Handihaler, Spiriva Respimat<\/span><\/p>\n<h3 id=\"4-oral-corticosteroids\"><span style=\"font-weight: 400;\">4. Oral corticosteroids<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Inflammation in COPD patients is unfortunately not just isolated to the lungs. There is inflammation linked to the cardiovascular system and other major organs which affects the quality of life. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2645327\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">Oral corticosteroid treatment<\/span><\/a><span style=\"font-weight: 400;\"> in COPD patients has been shown to improve lung function, shorten hospitalizations, and improve the shortness of breath that COPD patients experience. Unfortunately, long-term oral corticosteroid treatment is also linked to an increased risk of adverse effects such as hyperglycemia, hypertension (high blood pressure), and osteoporosis. Generally, if a COPD patient is considered stable and generally well-controlled on other treatments, oral corticosteroids would not be the best choice. However, for a patient with frequent relapses who is struggling to gain control of their severe COPD symptoms and carry on with normal daily functions of living, a longer-term regimen of oral corticosteroids may be a valid choice to regain control.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples: Medrol, Decadron&nbsp;<\/span><\/p>\n<h3 id=\"5-inhaled-short-acting-muscarinic-antagonist\"><span style=\"font-weight: 400;\">5. Inhaled short-acting muscarinic antagonist<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Ipratropium can be administered via oral inhaler or nebulizer and is an effective way to reverse bronchospasm associated with COPD. It is short-acting, and for many would only be appropriate as part of an acute treatment or rescue treatment plan. However, for patients with early stage, mild, stable, COPD, a short-acting muscarinic antagonist alone can provide effective control. It would not be appropriate for someone with more advanced disease.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Examples: Atrovent (ipratropium)<\/span><\/p>\n<h2 id=\"natural-alternatives-to-bevespi\"><span style=\"font-weight: 400;\">Natural alternatives to Bevespi<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">There really are no natural treatments for COPD, and there is no cure. The most effective non-medication approach you can do is live a healthy lifestyle that prevents the onset of COPD or decreases the symptoms if you already have COPD. This includes eating a diet of high-value nutrition, avoiding smoke and tobacco, and avoiding areas of high air pollution. Even sprays like bug spray or sunscreen are bad for your lungs if you constantly expose yourself to them. Maintaining a good amount of consistent physical activity is so important. It is very difficult to become active once COPD has set in.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There are other lifetime considerations of your health you should monitor. Maintain a healthy weight. Vaccinate yourself against preventable diseases, especially those which can affect your airways like influenza, pneumonia, and now coronavirus.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once you have COPD, you can not get rid of it. You can only manage it through healthy living and medications. Protect your lungs and your overall health with good choices your entire life.<\/span><\/p>\n<h2 id=\"how-to-switch-to-a-bevespi-alternative\"><span style=\"font-weight: 400;\">How to switch to a Bevespi alternative<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">If you or someone you know suffers from COPD, but are unsure that Bevespi is the best treatment option for you, speak with your healthcare provider. There are many more treatment options available that may be more appropriate for you or suit your price range better. The worst thing you can do is not do anything to treat your COPD. Never stop Bevespi Aerosphere or any COPD treatment without first seeking advice from your doctor. This could lead to sudden breathing problems and worsening of symptoms which could be severe or fatal. Work with your doctor or <\/span><a href=\"https:\/\/www.singlecare.com\/pharmacy-near-me\"><span style=\"font-weight: 400;\">pharmacist<\/span><\/a><span style=\"font-weight: 400;\"> to find a treatment option that is appropriate and <\/span><a href=\"https:\/\/www.singlecare.com\/browse-prescriptions\"><span style=\"font-weight: 400;\">affordable for you<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bevespi Aerosphere is an inhaled brand-name prescription drug product used in the maintenance treatment of chronic obstructive pulmonary disease (COPD). It is the combination of two drugs, glycopyrrolate, a long-acting muscarinic antagonist (LAMA), and formoterol fumarate, a long-acting beta-agonist (LABA). Although they work via their own distinct mechanisms, LAMAs and LABAs ultimately lead to bronchodilation, [&hellip;]<\/p>\n","protected":false},"author":133,"featured_media":55660,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[10965,790],"coauthors":[10437],"class_list":["post-55656","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-asthma","tag-chronic-disease","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Top Bevespi alternatives and how to switch your Rx | SingleCare<\/title>\n<meta name=\"description\" content=\"LABA and ICS combinations, LAMA, and inhaled short-acting muscarinic antagonists are some Bevespi alternatives. 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