{"id":56196,"date":"2023-01-04T16:14:00","date_gmt":"2023-01-04T21:14:00","guid":{"rendered":"https:\/\/www.singlecare.com\/blog\/?p=56196"},"modified":"2026-05-05T15:34:50","modified_gmt":"2026-05-05T19:34:50","slug":"cephalexin-alternatives","status":"publish","type":"post","link":"https:\/\/www.singlecare.com\/blog\/cephalexin-alternatives\/","title":{"rendered":"Cephalexin alternatives: What can I take instead of cephalexin?"},"content":{"rendered":"

Cephalexin<\/span><\/a> is a broad-spectrum <\/span>cephalosporin antibiotic<\/span><\/a> commonly used to treat a wide variety of bacterial infections, including skin infections, respiratory tract infections, ear infections, and others. Like many <\/span>antibiotics<\/span><\/a>, it can have intolerable or even hazardous side effects, including allergic reactions. When there\u2019s a problem, clinicians have a variety of other antibiotics they can use.\u00a0<\/span><\/p>\n

RELATED: <\/b>Common antibiotics & coupons<\/b><\/a><\/p>\n

What can I take in place of cephalexin?<\/span><\/h2>\n

Not all medications work for everyone. Luckily, there are several different antibiotic options available to treat bacterial infections if cephalexin does not prove effective or if unwanted side effects occur. Antibiotics, however, are not perfectly interchangeable. Some are more appropriate for certain types of infections than others. Preexisting medical conditions, including allergies, may also limit a healthcare provider\u2019s antibiotic choices.<\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n

\u00a0 \u00a0Cephalexin alternatives cost comparison<\/span><\/h3>\n<\/th>\n<\/tr>\n<\/thead>\n

Drug name<\/b><\/td>\nPrice without insurance<\/b><\/td>\nSingleCare price<\/b><\/td>\nSavings options<\/b><\/td>\n<\/tr>\n
Cephalexin<\/b><\/td>\n$45 per 28, 500 mg capsules of generic cephalexin<\/span><\/td>\n$9 per 28, 500 mg capsules of generic cephalexin at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Augmentin<\/b> (<\/b>amoxicillin<\/b>-clavulanic acid)<\/b><\/td>\n$768 per 1, 125\u201331.25 mg\/5 mL, 100 mL bottle<\/span><\/td>\n$11 per 20, 875\u2013125 mg tablets of generic Augmentin at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Amoxicillin<\/b><\/td>\n$19 per 21, 500 mg capsules of generic amoxicillin<\/span><\/td>\n$3 per 21, 500 mg capsules of generic amoxicillin at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Bactrim DS (sulfamethoxazole-trimethoprim)<\/b><\/td>\n$49 per 14, 800\u2013160 mg tablets<\/span><\/td>\n$3 per 14, 800\u2013160 mg tablets of generic Bactrim DS at Kroger<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Ciprofloxacin<\/b><\/td>\n$62 per 14, 500 mg tablets of generic ciprofloxacin<\/span><\/td>\n$8 per 14, 500 mg tablets of generic ciprofloxacin at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Doxycycline\u00a0<\/b><\/td>\n$98 for 14, 100 mg capsules of generic doxycycline<\/span><\/td>\n$8 for 14, 100 mg capsules of generic doxycycline at Walmart<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n
Erythromycin<\/b><\/td>\n$126 per 6, 500 mg tablets of generic erythromycin<\/span><\/td>\n$26 per 6, 500 mg tablets of generic erythromycin at CVS Pharmacy<\/span><\/td>\nSee latest prices<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Top 5 cephalexin alternatives<\/span><\/h2>\n

The following are some of the most common alternatives to cephalexin.<\/span><\/p>\n

1. Augmentin (amoxicillin\/clavulanate)<\/span><\/h3>\n

Augmentin<\/span><\/a> is a combination antibiotic that includes amoxicillin (a <\/span>penicillin antibiotic<\/span><\/a>) and clavulanate potassium (a beta-lactamase inhibitor). It is safe for use in adults and children, including infants and newborns. However, people with a penicillin allergy cannot safely take amoxicillin. Augmentin is capable of treating a variety of bacterial infections, such as Streptococcus (Strep) or Staphylococcus (Staph) aureus infections of the skin, ears, respiratory tract, and urinary tract.\u00a0<\/span><\/p>\n

Common Augmentin side effects<\/span><\/a> include diarrhea, nausea, rash, itching, vomiting, and vaginitis (irritation of the vagina or vulva). People with a history of liver problems while taking Augmentin or allergic reactions to Augmentin, any of its ingredients, or similar drugs should avoid using Augmentin.\u00a0<\/span><\/p>\n

Augmentin can also make birth control less effective, so an alternative for birth control will need to be discussed with your healthcare provider.\u00a0<\/span><\/p>\n

2. Bactrim (sulfamethoxazole\/trimethoprim)<\/span><\/h3>\n

Bactrim<\/span><\/a> is a brand-name <\/span>sulfonamide<\/span><\/a> antibiotic that contains sulfamethoxazole and trimethoprim, but it is available as a generic medication. It is approved for use in adults and children as young as 2 months old. Doses are administered as a tablet, oral suspension, or injection. Sulfamethoxazole\/trimethoprim can treat a variety of conditions, such as ear infections, Pneumocystis jirovecii pneumonia, traveler\u2019s diarrhea, <\/span>bronchitis<\/span><\/a> flare-ups, and <\/span>urinary tract infections<\/span><\/a>.\u00a0<\/span><\/p>\n

The most <\/span>common side effects<\/span><\/a> are digestive system complaints, like nausea, vomiting, and appetite loss, and allergic reactions, such as skin rash or hives. Allergies are a serious issue. People who have had an allergic reaction to sulfa drugs can\u2019t take Bactrim. Anyone who has an allergic reaction while taking the drug should stop taking doses and contact the prescriber.<\/span><\/p>\n

Bactrim can interact with several other drugs, such as warfarin, certain diabetes medications, and diuretics (water pills). It is important to tell your healthcare provider about all the drugs you take before you start Bactrim.\u00a0<\/span><\/p>\n

3. Cipro (ciprofloxacin)<\/span><\/h3>\n

Ciprofloxacin<\/span><\/a> is a <\/span>fluoroquinolone antibiotic<\/span><\/a> used in adults for a variety of infections, including gastrointestinal infections, kidney infections, and bone infections. It usually isn\u2019t used in children unless it is needed to treat more serious infections such as anthrax or the plague. It can be prescribed as a tablet, oral suspension, or injection.<\/span><\/p>\n

Serious <\/span>side effects<\/span><\/a> are associated with the use of ciprofloxacin, such as severe allergic reactions, seizures, psychosis, <\/span>depression<\/span><\/a>, suicidality, liver damage, <\/span>peripheral neuropathy<\/span><\/a>, and tendon rupture. Some of these side effects may not be reversible. This is usually why this antibiotic is not a first-line therapy.\u00a0<\/span><\/p>\n

4. Doxycycline<\/span><\/h3>\n

Doxycycline<\/span><\/a> is a <\/span>tetracycline antibiotic<\/span><\/a> that can be used in place of cephalexin when needed. There are several brand-name versions, like <\/span>Oracea<\/span><\/a> and <\/span>Doryx<\/span><\/a>, but most have specialized formulations or are used for particular infections. Indications for its use include gastrointestinal diseases, <\/span>urinary tract infections<\/span><\/a>, respiratory infections, sexually transmitted infections, and bacterial skin infections. <\/span>Acne<\/span><\/a> is one of the most common reasons doctors prescribe doxycycline. It can be administered orally or by injection.\u00a0<\/span><\/p>\n

Some <\/span>adverse reactions<\/span><\/a> when using this antibiotic include nausea, vomiting, diarrhea, vaginal itching and discharge, headache, abdominal pain, candidiasis, skin\/tissue hyperpigmentation, and permanent\/temporary tooth discoloration. Doxycycline cannot be used while pregnant or breastfeeding. It should be used cautiously with birth control, antacids, laxatives, or vitamin supplements.\u00a0<\/span><\/p>\n

5. Erythromycin<\/span><\/h3>\n

Erythromycin<\/span><\/a> is a generic <\/span>macrolide antibiotic<\/span><\/a>, though it can be purchased as a brand-name drug. Erythromycin has been approved to treat a variety of bacterial infections, such as respiratory tract infections, skin infections, chlamydia infections, pelvic inflammatory disease, and syphilis. Erythromycin is an oral antibiotic taken as a tablet, capsule, or oral suspension.<\/span><\/p>\n

Side effects associated with its use include nausea, vomiting, abdominal pain, diarrhea, and anorexia. More serious adverse effects include liver damage, hearing loss, and seizures. Because of potential problems, patients with known liver disease and those with low potassium or magnesium, will need to be monitored when taking this drug.\u00a0<\/span><\/p>\n

Natural alternatives to cephalexin<\/span><\/h2>\n

There are natural bacteria-fighting remedies, many of which can be purchased over the counter. Because natural antibiotics have not been fully studied, though, it is best to discuss using these alternatives with your healthcare provider. They may want to monitor the bacterial infection closely to ensure it is healing properly. For some bacterial infections, natural treatments may not be a suitable substitute for prescription antibiotics.\u00a0<\/span><\/p>\n

As an add-on treatment, however, natural alternatives could help. There are several <\/span>naturally occurring compounds<\/span><\/a> that have been shown to slow or arrest bacterial infections. Most can be purchased over the counter, such as honey, garlic, oregano, thyme, and turmeric.\u00a0<\/span><\/p>\n

Raw honey has been around for centuries. There has been research that shows it is effective for healing wounds and drawing out infection. Honey can be applied directly to the infected site or ingested.\u00a0<\/span><\/p>\n

Apple cider vinegar<\/span><\/a> is another natural remedy known for its antimicrobial properties. Research shows that it may fight against minor Candida albicans, E. coli, and Staphylococcus aureus infections.\u00a0<\/span><\/p>\n

RELATED: <\/b>Why you should take probiotics with antibiotics<\/b><\/a><\/p>\n

How to switch to a cephalexin alternative<\/span><\/h2>\n

Abruptly stopping antibiotics, such as <\/span>cephalexin<\/span><\/a>, without proper guidance from your healthcare provider may cause the infection to return or cause the symptoms to get worse. Before you <\/span>discontinue<\/span><\/a> your cephalexin, get proper medical advice and instructions from your healthcare provider. Another antibiotic will likely need to be substituted. If this is the case, <\/span>SingleCare coupons<\/span><\/a> may help with purchasing your new antibiotic at a lower cost.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Cephalexin is a broad-spectrum cephalosporin antibiotic commonly used to treat a wide variety of bacterial infections, including skin infections, respiratory tract infections, ear infections, and others. Like many antibiotics, it can have intolerable or even hazardous side effects, including allergic reactions. When there\u2019s a problem, clinicians have a variety of other antibiotics they can use.\u00a0 […]<\/p>\n","protected":false},"author":133,"featured_media":56202,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4589],"tags":[715],"coauthors":[20627],"class_list":["post-56196","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-drug-info","tag-antibiotics","wpautop"],"acf":[],"yoast_head":"\nTop cephalexin alternatives and how to switch your Rx<\/title>\n<meta name=\"description\" content=\"Augmentin, Bactrim, Cipro, doxycycline, and erythromycin are some cephalexin alternatives. 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